--- title: 'Accounting Operations Manager at DELFI Diagnostics, Inc.' canonical: 'https://feeny.ai/job/accounting-operations-manager-delfi-diagnostics-inc-palo-alto-2q3fjaratz5w' type: 'job' last_seen: '2026-09-12' --- # Accounting Operations Manager at DELFI Diagnostics, Inc. - **Company:** DELFI Diagnostics, Inc. - **Location:** Palo Alto, CA - **Compensation:** $140k–$175k - **Employment:** full-time - **Work type:** hybrid - **Posted:** 2026-09-09 - **Last confirmed live:** 2026-09-12 - **Apply:** https://jobs.lever.co/delfidiagnostics/dfc8cada-f1f4-4209-9a0a-5bfc0ae02a5e ## Job description DELFI Diagnostics, Inc. (DELFI Diagnostics) is developing next-generation, blood-based tests that are reliable, accessible and deliver a new way to help detect cancer. Employing advanced machine-learning methods to whole-genome sequencing data, the DELFI ("DNA EvaLuation of Fragments for early Interception") platform is built to address the highest-burden health challenges. DELFI Diagnostics prioritizes solutions that have the potential to save lives on a global scale, including for historically underserved populations. DELFI Diagnostics’ platform relies on fragmentomics – the discovery that cancer cells are more chaotic than normal cells and, when they die, leave behind tell-tale patterns and characteristics of cell-free DNA (cfDNA) fragments. FirstLook Lung, for individuals eligible for lung cancer screening, is DELFI Diagnostics’ first laboratory-developed screening test and can be part of routine blood work. FirstLook Lung uses millions of data points to reliably identify individuals who may have cancer detected through low-dose CT, including early stage disease with a negative predictive value of 99.8 percent. This test has not been cleared or approved by the FDA. In our passionate pursuit to radically improve health outcomes, we serve humanity when we: Lead with Science, Anchor in Pragmatism: We pioneer life-changing science by ensuring quality, transparency, and rigor at all times. We explore thoughtfully, experiment smartly, and deliver impact with conviction. Build With & For All: We embrace diverse backgrounds to innovate and achieve together. We are not just building a product - we aim to disrupt the path of cancer for all - no matter geography or socioeconomic class Put We over I: We are a home for high-performing people. Through teamwork, we build collective intelligence. Each of us wins when those we serve and those who serve with us--win. We show up with empathy, humility, and integrity at every step of the journey. DELFI has 1-2 designated in-office working days each week for employees who live within within 50 miles of Palo Alto, CA ## What You'll Do Procure-to-Pay (P2P) - End-to-end ownership of the P2P cycle: requisition, PO issuance, invoice matching, and payment - Manage PO and invoice issues to ensure timely resolution - Design and implement a scalable procurement process - Recommend and implement automated solutions to support P2P - Vendor onboarding, W-9/W-8 collection, ensuring valid vendor payment data, vendor master data integrity in NetSuite - Manage relationships with AP-adjacent vendors (e.g., bill pay, corporate card providers) - Monthly AP close activities: accruals, aging review, partner with FP&A to inform cash planning - Work with R&D teams to understand projected order volumes and timing - Sets re-order points and modify as the company expands - Monitor critical vendors to ensure quoted prices are reasonable, including assisting with vendor consolidation and price negotiation related to high volume and high spend items Accounts Receivable (AR) - Liaise with external vendor and internal customer experience team to reconcile AR on a monthly basis, including troubleshooting discrepancies with external vendor - Generate and send invoices using NetSuite - Liaise with internal customer experience team to ensure write-offs are recorded into NetSuite timely Expense Reports and Credit Cards - Ensure proper onboarding and offboarding - Timely approval of expenses - Provide insight and analysis to FP&A on spend - Work with vendors where needed to negotiate better prices on high spend areas General Accounting - Monthly review of financials to ensure accuracy of PO coding to general ledger accounts and departments - Journal entries and reconciliations for P2P, AR, expense report accrual, credit card accrual - Demonstrate technical accounting knowledge through leveraging understanding of developments within the business to identify accounting risks in owned accounting areas - Monthly financial reporting support, including flux explanations for P2P, AR, expense reports, credit cards NetSuite & Systems Ownership - Serve as the primary finance internal administrator for NetSuite: timely additions and removals of users, user roles/permissions, workflow configuration, workflow troubleshooting, approval routing, custom fields/forms, reporting - Own the relationship with NetSuite technical admin support: system changes, upgrades, custom workflows, automation, and troubleshooting - Manage integrations between NetSuite and adjacent systems (expense management, procurement/e-sourcing tools, banking/payment platforms, potentially LIMS-adjacent data feeds for lab spend) Policy & Controls - Own and maintain the corporate approval matrix (spend authority by role, dollar thresholds, PO vs. non-PO approval paths) - Own the expense reimbursement policy and T&E program, including corporate card administration - Design and enforce segregation-of-duties controls appropriate for a pre-IPO/pre-commercial dx company preparing for future audit and compliance scrutiny (SOX readiness, external audit support) - Maintain documentation (SOPs, process flows) for all owned processes to support internal controls and audit requests Cross-Functional & Leadership - Partner with lab operations, R&D, and clinical teams on purchasing needs specific to a dx/life sciences environment (reagents, instruments, CRO/CDMO spend, biospecimen-related purchases) - Support the Controller and CFO with ad hoc analysis on vendor spend, contract terms, and cost management opportunities - Likely people leadership: this role may have 1+ direct report(s) performing transactional P2P/AP work - Experience with improving and automating processes through system reporting improvements and AI tools ## What You'll Bring Required - 7-10+ years of progressive accounting/finance operations experience, including direct ownership of P2P and ERP systems administration - Hands-on NetSuite experience required (administrator-level configuration, not just end-user) - Experience building or scaling accounting, procurement, P2P processes in a growing company (~50-200 employees) - Strong understanding of internal controls and segregation of duties - Comfortable operating without a large team — you will be expected to build processes and solutions from the ground up without a team under you Strongly Preferred - Life sciences, diagnostics, biotech, or pharma industry experience - Experience in a pre-commercial or recently-commercial company preparing for SOX compliance or external audit scrutiny - Exposure to lab operations, CRO/CDMO vendor management, or clinical trial-related spend - Experience with P2P solutions integrated with NetSuite (e.g., NetSuite Bill Capture, Coupa, Airbase) - Experience with expense management platforms (e.g., ChromeRiver, Expensify, Navan/TripActions) integrated with NetSuite ## Nice to Have - CPA, CMA, or other relevant certification - Prior experience in a company undergoing M&A or strategic transaction diligence (given the level of financial rigor and documentation that entails) We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. ## About DELFI Diagnostics, Inc. ## Company Overview - **One-liner**: DELFI Diagnostics is a precision oncology company that uses AI and whole-genome sequencing to analyze DNA fragmentation patterns in blood for early cancer detection. - **Entity Type**: Private (Late-Stage) - **Headquarters**: Palo Alto, California, USA - **Founded**: 2019 - **Founders**: Victor Velculescu, MD, PhD (and colleagues at Johns Hopkins University) ## Core Business - Primary industry: Precision Oncology / Liquid Biopsy / Healthcare Diagnostics - Target customers: B2B (Health systems, primary care providers, pulmonologists, lung screening programs) and B2B for research (Pharmaceutical companies) - Mission: "Make cancer less deadly through widely accessible early detection" ## Products & Services - **[FirstLook™ Lung](https://delfidiagnostics.com/)**: A blood-based, AI-powered laboratory-developed test (LDT) for lung cancer screening. Designed for adults eligible under USPSTF guidelines, it uses whole-genome sequencing and machine learning to analyze cell-free DNA fragmentation patterns. It boasts a 99.8% Negative Predictive Value and is intended to be a noninvasive first step before low-dose CT (LDCT) scans. Became commercially available in October 2023. - **[DELFI-TF Treatment Monitoring](https://delfidiagnostics.com/)**: A research service for pharmaceutical companies conducting Phase 1-2 clinical trials. It provides non-invasive, real-time treatment response assessment using cell-free DNA fragmentomes, offering short turnaround times and a low-cost solution. ## Market Standing - **Valuation**: Not publicly disclosed - **Key Metric**: Total Funding of **over $325 million** - **Notable Investors/Partners**: DFJ Growth, Eli Lilly and Company, Merck Global Health Innovation Fund (equity investment announced June 2024), OrbiMed, Point72, T. Rowe Price. - **Growth Signals**: - The FirstLook Lung test is commercially available, marking a major milestone from R&D to clinical deployment. - Completed three major clinical trials (L101 validation study, CASCADE-LUNG/L201 prospective cohort study, L301/FIRSTLUNG randomized controlled trial). - Has a strong intellectual property foundation, with its core technology first published in *Nature* in 2019. - Strategic equity investment from Merck (2024) signals pharma validation and potential for partnership. ## Competitive Advantages - **Proprietary Fragmentomics Platform**: Their AI-driven computational platform analyzes genome-wide patterns of cell-free DNA fragmentation, capturing signals that conventional mutation-based liquid biopsies often miss. This provides a broader, more sensitive view of cancer biology. - **Strong Clinical Validation**: The technology is backed by peer-reviewed publications in top journals (*Nature*, *Cancer Discovery*) and multiple registered clinical trials (NCT04825834, NCT05306288, NCT06145750). - **High Clinical Utility**: The test's 99.8% Negative Predictive Value provides high confidence to rule out lung cancer, which is a powerful tool for clinicians managing screening decisions. - **Focus on Accessibility**: Designed for large-scale health system deployment with EHR integration, provider support, and a low-cost structure to make screening widely available. ## Strategic Focus - **Market Expansion**: Driving commercial adoption of FirstLook Lung within health systems, primary care, and lung screening programs across the US. - **Clinical Evidence Generation**: Continuing to generate robust clinical data through trials like CASCADE-LUNG to further validate the technology's performance and clinical utility. - **Pharma Partnerships**: Expanding the DELFI-TF treatment monitoring service to partner with more pharmaceutical companies for drug development. - **Product Pipeline**: Likely developing additional screening tests for other cancer types using the same fragmentomics platform. ## Why Work Here - **High-Impact Mission**: The company is singularly focused on "making cancer less deadly," offering employees a direct role in a potentially transformative technology. - **Culture & Values**: DELFI emphasizes three core values guiding all interactions and decisions. They actively seek to build a diverse, inclusive, and healthy workplace so employees can do their best work. - **Hybrid/Remote Flexibility**: DELFI supports hybrid and remote work options for most positions, with labs and offices in Palo Alto, CA, and Baltimore, MD. Employees receive a one-time $400 home office subsidy. - **Comprehensive Compensation**: Offers a competitive base salary, target bonus plan, and an equity program so everyone has a stake and feels ownership. - **Generous Benefits**: - Non-accrual time off (flexible PTO) and a 5-day winter break. - DELFI pays 100% of the medical premium for employee and family. - 16 weeks of paid parental leave. - 401(k) and annual merit cycle. - **Learning & Growth**: Wide-ranging learning and development programs to help employees continue to develop their skills. - **Team & Leadership**: A dynamic, passionate group of executive leaders, clinical and data scientists, engineers, and commercial team members, led by experienced experts from relevant fields. ## Sources 1. [delfidiagnostics.com](https://delfidiagnostics.com/) 2. [delfidiagnostics.com/about-us/](https://delfidiagnostics.com/about-us/) 3. [delfidiagnostics.com/about-us/careers/](https://delfidiagnostics.com/about-us/careers/) 4. [jobs.lever.co/delfidiagnostics](https://jobs.lever.co/delfidiagnostics) 5. [delfidiagnostics.com/about-us/leadership-team/](https://delfidiagnostics.com/about-us/leadership-team/) ## Other roles at DELFI Diagnostics, Inc. - [Manager Equipment Service Engineering](https://feeny.ai/job/manager-equipment-service-engineering-delfi-diagnostics-inc-palo-alto-ev10x2yvgs6c) — Palo Alto, CA - [Sr. Data Scientist, Assay Development](https://feeny.ai/job/sr-data-scientist-assay-development-delfi-diagnostics-inc-palo-alto-e021867zf5tq) — Palo Alto, CA - [Director / Senior Director, Market Access & Reimbursement](https://feeny.ai/job/director-senior-director-market-access-reimbursement-delfi-diagnostics-inc-n4z44ygzc0e5) - [Senior Clinical Laboratory Associate / Equipment Engineer (Contract)](https://feeny.ai/job/senior-clinical-laboratory-associate-equipment-engineer-contract-delfi-59t1g1rbhy4a) — Palo Alto, CA - [IVD Documentation Scientist, Manufacturing and Medical Device (Contract)](https://feeny.ai/job/ivd-documentation-scientist-manufacturing-and-medical-device-contract-delfi-zzcfhgh4mdm8) — Palo Alto, CA - [Automation Engineer I/II (Contract)](https://feeny.ai/job/automation-engineer-i-ii-contract-delfi-diagnostics-inc-palo-alto-zfxef259gcph) — Palo Alto, CA - [Senior Director, Clinical Development](https://feeny.ai/job/senior-director-clinical-development-delfi-diagnostics-inc-palo-alto-06vxbzpnzjqq) — Palo Alto, CA - [Senior Staff, Software Engineer](https://feeny.ai/job/senior-staff-software-engineer-delfi-diagnostics-inc-remote-bjpcbxmnjyd2)