---
title: 'Associate Director, Clinical Research & Real-World Evidence at Sequel Med Tech'
canonical: 'https://feeny.ai/job/associate-director-clinical-research-real-world-evidence-sequel-med-tech-shfg9ge3qzfw'
type: 'job'
last_seen: '2026-11-06'
---

# Associate Director, Clinical Research & Real-World Evidence at Sequel Med Tech

- **Company:** Sequel Med Tech
- **Location:** Manchester, NH
- **Compensation:** $170k–$220k
- **Employment:** full-time
- **Work type:** remote
- **Posted:** 2026-10-22
- **Last confirmed live:** 2026-11-06
- **Apply:** https://jobs.lever.co/sequel-med-tech/cd4ea1bd-ce77-443d-97cf-758b44183076

## Job description

## About Sequel

Sequel, headquartered in Manchester, New Hampshire, is a company developing the next generation of transformative drug-delivery advancements starting with diabetes. Sequel’s approach is to look at diabetes management holistically to advance systems that make living with diabetes simpler and easier for all. Sequel’s flagship product, the twiist Automated Insulin Delivery (AID) System, launched in July 2025 for people with type 1 diabetes providing them with personalized diabetes management.

Job Responsibilities and Essential Duties

- Real-World Evidence & Biostatistics: Design and support RWE studies; contribute to research questions, endpoint definitions, analysis plans, data-quality review, interpretation, and communication of results; partner effectively with internal or external statisticians and data scientists.
- Study Design & Regulatory Support: Lead the development of study protocols and study concepts for company-sponsored, collaborative, post-market, and pivotal studies, including objectives, populations, comparators, endpoints, sample-size considerations, and analysis approaches; develop clinical evidence for regulatory briefing materials, submissions, and responses.
- Clinical Research Execution: Drive study start-up and execution, including protocol and case-report-form development, vendor and investigator coordination, data review, issue resolution, analysis, and interpretation across company-sponsored studies, investigator-initiated studies, and special-population research.
- Evidence Planning: Partner with the CMO to identify evidence gaps and research priorities and drive an integrated evidence-generation plan spanning clinical studies, real-world evidence, publications, and external collaborations.
- Clinical Evidence Development: Develop  clinical evidence materials, including competitive data comparisons, dossiers, evidence summaries, and scientific narratives supporting regulatory, reimbursement, product adoption, medical education, publications, and OUS opportunities.
- Payer / Market Access: Develop clinical and economic evidence summaries supporting reimbursement, payer engagements, and market-access activities.
- Publications & Scientific Communications: Support scientific publications, abstracts, posters, congress presentations, and dissemination of clinical and real-world evidence.
- Medical Affairs Strategy: Contribute to the  execution of the Medical Affairs strategy and evidence roadmap, supporting clinical adoption, reimbursement, patient outcomes, and future growth objectives.
- Medical Education & Scientific Engagement: Serve as a scientific resource across the product portfolio; support advisory boards, congress activities, medical education programs, and engagement with healthcare professionals, investigators, and key opinion leaders.
- Medical Safety: Participate in hazard analysis reviews, adverse-event and complaint evaluations for Sequel owned product, post-market safety activities, and related investigations.

## Minimum Requirements

- Education: Advanced degree in biostatistics, epidemiology, health outcomes research, clinical research, public health, or a relevant scientific or healthcare discipline (e.g., PhD, ScD, DrPH, PharmD, MD, or MS).
- Experience: 5+ years of relevant experience in clinical research, RWE, biostatistics, epidemiology, medical device or pharmaceutical evidence generation, or a related field; a doctoral degree may substitute for a portion of professional experience.
- Experience in a regulated medical device, pharmaceutical, biotechnology, academic research, contract research, or health-data environment; direct experience supporting regulatory activities is preferred.

Required Knowledge, Skills and Abilities

- Strong knowledge of clinical study design, observational research, registry studies, and real-world evidence methods.
- Applied understanding of biostatistical principles, including endpoint selection, sample-size and power considerations, longitudinal and repeated-measures data, missing data, confounding, bias mitigation, and interpretation of clinical and real-world analyses.
- Ability to develop or critically review protocols, statistical analysis plans, tables and figures, and study reports, and to collaborate effectively with statisticians and programmers.
- Experience supporting clinical research execution, including investigator or vendor collaboration, data review, and interpretation of study findings.
- Familiarity with FDA expectations, Good Clinical Practice, and clinical evidence requirements for regulated products; medical device experience is preferred.
- Knowledge of clinical research and regulatory requirements outside the U.S., including experience supporting global or international evidence-generation activities, is preferred.
- Experience preparing abstracts, posters, manuscripts, evidence summaries, or other scientific communications.
- Knowledge of diabetes management, insulin therapy, continuous glucose monitoring, and Automated Insulin Delivery systems is preferred.
- Strong scientific writing, communication, project management, and cross-functional collaboration skills.
- Ability to work independently, manage multiple research activities, and translate evidence into clear scientific, clinical and business insights.

Sequel Med Tech provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

At Sequel, we believe that when you thrive, we thrive. That’s why our benefits package is designed to support you from day one. You’ll be automatically enrolled in our 401k plan, featuring a 6% company match and 100% immediate vesting. We’re committed to your well-being and understand the unique needs of employees and families living with diabetes, so we offer capped out-of-pocket insulin costs and GLP-1 coverage across all plans. You’ll have access to a variety of Meritain health insurance plans to suit your needs and can also take advantage of Flexible Spending Accounts (FSAs) or Health Savings Account (HSA). Our comprehensive benefits package includes vision and dental coverage, plus voluntary options such as long-term disability, accident, critical illness, hospital indemnity, and even discounts for pet care. In addition, we provide employer-paid short-term disability and life insurance for extra peace of mind.

We know the importance of taking time to rest and recharge. That’s why Sequel offers flexible PTO, generous paid holidays, and Flex Time options to help you balance work and life when you need it most. Our team enjoys a culture built on hard work, fun, and genuine support. At Sequel, you’re not just starting a job, you’re building a rewarding career and a brighter future. Join us, and let’s thrive together!

Environmental/Safety/Physical Work Conditions Ensures environmental consciousness and safe practices are exhibited in decisions Use of computer and telephone equipment and other related office accessories/devices to complete assignments May work extended hours during peak business cycles Physical requirements such as lifting specific weights Some travelling is expected

## About Sequel Med Tech

## Company Overview
- **One-liner**: Sequel Med Tech is a medical device company that develops and commercializes the twiist Automated Insulin Delivery (AID) system, the first system to directly measure the volume of insulin delivered with every microdose using sound wave technology.
- **Entity Type**: Private (Startup stage; no funding rounds publicly disclosed)
- **Headquarters**: Manchester, New Hampshire, United States
- **Founded**: 2023
- **Founders**: Alan Lotvin (CEO, Co-Founder, and Director); co-founders not publicly named

## Core Business
- Primary industry: Medical Equipment Manufacturing / Diabetes Care
- Target customers: B2B and B2C — people with diabetes, healthcare providers, payers (health plans, employers), and pharmaceutical partners
- Mission or purpose statement: To elevate the standard for drug delivery and remove barriers for accessible revolutionary insulin therapy

## Products & Services
- **[twiist Automated Insulin Delivery (AID) System]**: The company’s flagship product — a hardware/software system integrating a pump, continuous glucose monitor, and algorithms. It uses proprietary iiSure™ sound wave technology to measure actual insulin volume delivered at every microdose, offering unprecedented dose assurance. Delivered through pharmacy channels for affordability.
- **[SequelConnect™]**: An employer and health plan benefits platform designed to make medical devices more affordable and accessible for groups.

## Market Standing
- **Valuation/Market Cap**: Not publicly disclosed
- **Key Metric**: Total employees — 365 (as of Q2 2026); 16,167 LinkedIn followers (growing at +1.3% monthly)
- **Notable Investors/Partners**: Not publicly disclosed; the company works with payers, employers, and pharma partners to design and develop delivery systems
- **Growth Signals**: Founded in 2023, already a team of 365 with a flagship product launched; 96% of employees say it’s a Great Place to Work (as of 2025); actively hiring across roles (e.g., Clinical Diabetes Specialists, IT Operations, VP Commercial Excellence); workforce distributed across US, Canada, France, and Pakistan

## Competitive Advantages
- **Proprietary iiSure™ sound wave technology**: A unique moat — the only AID system that directly measures delivered insulin volume, enabling greater accuracy and confidence for patients and providers.
- **Pharmacy channel distribution**: Delivers AID systems through pharmacies, lowering barriers compared to traditional durable medical equipment (DME) channels.
- **Integrated ecosystem**: Built-in connectivity across delivery devices, algorithms, monitoring devices, and partners — not an afterthought.
- **Strong culture and talent retention**: 96% employee Great Place to Work rating, with 64% women in the workforce (Q2 2026).

## Strategic Focus
- Scaling commercial reach by hiring Clinical Diabetes Specialists across the US (e.g., Baltimore, Corpus Christi, Seattle)
- Expanding beyond type 1 diabetes into broader drug delivery applications (the company notes exploring “how precise drug delivery can support people far beyond type 1 diabetes”)
- Deepening partnerships with payers and employers to drive adoption of SequelConnect™
- Building a diverse, high-performing team with a focus on engineering, clinical outcomes, and real-world impact

## Why Work Here
- **Culture**: Described as “hard work, fun, and genuine support” with a focus on curiosity, experimentation, and transparency. Employees report high levels of accountability and compassion.
- **Hybrid/Office policy**: Hybrid model with offices in Manchester, NH and Marlborough, MA. Some roles (e.g., Clinical Diabetes Specialists) are field-based.
- **Notable perks & benefits**:
  - 6% 401k match with 100% immediate vesting
  - Capped out-of-pocket costs for insulin and GLP-1 coverage on all health plans
  - Comprehensive health insurance (Meritain), vision, dental, disability, life insurance, and pet care discounts
  - Flexible PTO plus generous paid holidays
  - Employer-paid short-term disability and life insurance
- **Hiring process**: Starts with a recruiter phone/video screen; typical timeline is 3–6 weeks; no AI used in hiring; applicants must be authorized to work in the US (no visa sponsorship currently)
- **Engineering culture**: “Approach problems with curiosity and experimentation, always pushing against traditional boundaries and norms”

## Sources
1. [sequelmedtech.com](https://www.sequelmedtech.com/)
2. [sequelmedtech.com/careers](https://www.sequelmedtech.com/careers)
3. [sequelmedtech.com/about](https://www.sequelmedtech.com/about)
4. [cbinsights.com](https://www.cbinsights.com/company/sequel-med-tech)
5. [linkedin.com/company/sequel-med-tech](https://www.linkedin.com/company/sequel-med-tech)

## Other roles at Sequel Med Tech

- [Associate Validation Engineer - Test Automation](https://feeny.ai/job/associate-validation-engineer-test-automation-sequel-med-tech-manchester-zaazcmdfn16f) — Manchester, NH
- [Clinical Diabetes Specialist - Jacksonville](https://feeny.ai/job/clinical-diabetes-specialist-jacksonville-sequel-med-tech-jacksonville-6tjn79xr7qvh) — Jacksonville, FL
- [Clinical and Medical Research Specialist](https://feeny.ai/job/clinical-and-medical-research-specialist-sequel-med-tech-marlborough-9j8xtnp0e59k) — Marlborough, MA
- [Regional Business Leader - New England](https://feeny.ai/job/regional-business-leader-new-england-sequel-med-tech-boston-smg4kyzn9td5) — Boston, MA
- [Clinical Diabetes Specialist - Los Angeles](https://feeny.ai/job/clinical-diabetes-specialist-los-angeles-sequel-med-tech-los-angeles-nwpkzf3a211q) — Los Angeles, CA
- [Senior Systems Engineer - NetSuite](https://feeny.ai/job/senior-systems-engineer-netsuite-sequel-med-tech-manchester-s76zg7rm2m2b) — Manchester, NH