--- title: 'Associate Director, Clinical Supply Management (UK/EU) at Summit Therapeutics' canonical: 'https://feeny.ai/job/associate-director-clinical-supply-management-uk-eu-summit-therapeutics-oxford-4hve8zj7pay9' type: 'job' last_seen: '2026-10-16' --- # Associate Director, Clinical Supply Management (UK/EU) at Summit Therapeutics - **Company:** Summit Therapeutics - **Location:** Oxford UK Zug Switzerland Dublin, Ireland - **Compensation:** $83k–$98k - **Posted:** 2026-10-15 - **Last confirmed live:** 2026-10-16 - **Apply:** https://job-boards.greenhouse.io/summittherapeutics/jobs/4451559009 ## Job description About Summit: Summit Therapeutics Inc. is a biopharmaceutical oncology company with a mission focused on improving quality of life, increasing potential duration of life, and resolving serious unmet medical needs. At Summit, we believe in building a team of world class professionals who are passionate about this mission, and it is our people who drive this mission to reality. Summit’s core values include integrity, passion for excellence, purposeful urgency, collaboration, and our commitment to people. Our employees are truly the heart and soul of our culture, and they are invaluable in shaping our journey toward excellence. Summit’s team is inspired to touch and help change lives through Summit’s clinical studies in the field of oncology. Summit has multiple global Phase 3 clinical studies, including: Non-small Cell Lung Cancer (NSCLC) - HARMONi: Phase 3 clinical study which was intended to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who were previously treated with a 3rd generation EGFR TKI. - HARMONi-3: Phase 3 clinical study which is intended to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC. - HARMONi-7: Phase 3 clinical study which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC. Colorectal Cancer (CRC) - HARMONi-GI3: Phase 3 clinical study intended to evaluate ivonescimab in combination with chemotherapy compared with bevacizumab plus chemotherapy. Ivonescimab is an investigational therapy not presently approved by any regulatory authority other than China’s National Medical Products Administration (NMPA). Summit is headquartered in Miami, Florida, and has additional offices in California, New Jersey, the UK, and Ireland. Job Title: Sr. Medical Science Liaison Location: Oxford, UK or Zug, Switzerland or Dublin, Ireland Overview of Role: The Associate Director, Clinical Supply Management supports the Senior Director in leading the full scope of global clinical supply chain responsibilities. The role translates functional strategy into disciplined execution across demand and supply planning, inventory management, packaging and labelling, distribution, returns and destruction, cross-border compliance, and GxP operations. Acting as a key delegate for the Senior Director, the (Associate) Director provides a layer of management for direct reports, establishes clear priorities and performance expectations, develops team capability, and drives operational excellence through standardized processes, meaningful metrics, proactive risk management, and continuous improvement. The role partners closely with Clinical Operations, Commercial, CMC, Quality, Regulatory, Finance, Legal, Procurement, Medical Affairs and Program Management, and oversees external partners including Contract Development and Manufacturing Organizations (CDMOs), IXRS providers and specialist service providers. Role and Responsibilities: - Supports the Senior Director in developing functional strategy, operating plans, budgets, governance and performance objectives across global clinical supply chain activities - Leads day-to-day execution for new and ongoing studies and products, ensuring robust forecasting, supply planning, schedule adherence, inventory optimization, global logistics and sustained GxP compliance - Serves as a delegate for the Senior Director in cross-functional forums, governance meetings, supplier reviews and issue escalation, providing clear recommendations and ensuring timely follow-through. - Manages and develops direct reports, translating functional priorities into individual objectives, balancing workloads, coaching performance, supporting career development and ensuring appropriate succession and capability plans. - Creates an effective management layer by coordinating team activities, reinforcing accountability, removing operational barriers and escalating material risks or decisions to the Senior Director. - Overseeing the Clinical Supply Management (CSM) team, the Associate Director interprets complex clinical protocols, development plans and commercial demand forecasts, working with CMC and internal and external partners to develop packaging, labelling, supply and resupply strategies, timelines and plans. - Supports the accountability of CSM team to oversee packaging, labelling, release, distribution, resupply, returns, reconciliation and destruction activities across global locations - Develops and maintains supply project budgets, resource plans and integrated schedules, monitors performance and proactively resolves variances - Manages CDMO and service-provider activities from RFP and contracting support through routine operations, troubleshooting, invoicing and performance management using defined KPIs and service expectations - Supports IXRS selection, design, set-up, User Acceptance Testing (UAT), implementation and ongoing operational performance as required by IRT Management Team. - Drives operational excellence by defining standard work, governance routines, KPIs and dashboards; uses trend and root-cause analysis to improve service, quality, cost, compliance and team productivity - Leads continuous-improvement initiatives that streamline and harmonize processes, strengthen inspection readiness and embed sustainable ways of working - Supports regulatory submissions, audits and inspections and ensures timely management of SOPs, change controls, deviations, investigations and CAPAs within the function - Provides continuity of leadership and performs other responsibilities within the function as assigned Experience, Education and Specialized Knowledge and Skills: - BSc, MSc, engineering or pharmacy degree, or equivalent, with a minimum of 8+ years of progressive supply chain experience in a pharmaceutical, biotechnology or contract development and manufacturing organization (CDMO) environment - Demonstrated success leading complex international clinical studies and product supply chains, with broad knowledge of regulatory and GMP requirements for IMP and commercial product packaging and supply - Prior people-management experience, including setting objectives, coaching performance, developing talent, delegating effectively and managing through others - Demonstrated ability to translate strategy into executable priorities, operating rhythms, metrics and measurable team outcomes - Strong operational-excellence and continuous-improvement capability, including process standardization, KPI management, root-cause analysis and sustainable implementation of improvements - Solid understanding of IXRS design specifications, set-up and UAT, together with proficiency in clinical supply planning and forecasting tools - Strong project, budget, risk and resource-management skills, with the ability to manage multiple priorities while maintaining high-quality results - Expertise in outsourcing, supplier governance, negotiation and performance management - Experience building, scaling or improving end-to-end product supply chains and associated business processes - Ability to operate as a trusted deputy to the Director, exercise sound judgement within delegated authority and escalate issues with clear options and recommendations - Confident communicator able to influence all levels of the organization and build effective relationships with global colleagues, customers and suppliers - Able to work independently with complex global problems while fostering inclusion, collaboration, accountability and effective team leadership - Agile and resilient in a dynamic organization where priorities may change rapidly - Knowledge of the drug development process and applicable FDA, EMA and PMDA expectations, including GMP, GCP, Annex 13 and relevant clinical trial requirements - Technically proficient with industry-standard systems and tools and able to use technology, data and industry trends to improve efficiency and decision-making - Knowledgeable of and compliant with SOPs, change controls, deviations, investigations and CAPAs This is the pay for this position Pay Transparency $83,000—$97,500 USD Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation. Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit’s Talent Acquisition team at recruiting@smmttx.com to obtain prior written authorization before referring any candidates to Summit. Summit Therapeutics Inc. is an Equal Opportunity Employer and takes pride in creating and maintaining diverse environment. We do not discriminate in recruitment, hiring, training or promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. ## About Summit Therapeutics ## Company Overview - **One-liner**: Summit Therapeutics Inc. is a biopharmaceutical oncology company focused on discovering, developing, and commercializing novel bispecific antibody therapies, with its lead candidate ivonescimab targeting PD-1 and VEGF for multiple solid tumors. - **Entity Type**: Public (NASDAQ: SMMT) - **Headquarters**: Miami, Florida, USA (with additional offices in Palo Alto, CA; Princeton, NJ; Oxford, UK; and Dublin, Ireland) - **Founded**: 2003 - **Founders**: Not publicly disclosed on the company website; the company was founded in 2003. ## Core Business - **Primary industry**: Biopharmaceuticals / Oncology - **Target customers**: B2B (healthcare providers, patients, and caregivers) with a focus on resolving serious unmet medical needs in oncology - **Mission statement**: "To resolve serious, unmet medical needs for the betterment of overall human health." [smmttx.com](https://smmttx.com/company/about-us/default.aspx) ## Products & Services - **Ivonescimab (SMT112)**: A novel, potential first-in-class investigational bispecific antibody targeting both PD-1 and VEGF. It is designed to combine immunotherapy (PD-1 blockade) with anti-angiogenesis (VEGF blockade) into a single molecule. Currently being studied in several global Phase 3 clinical trials for non-small cell lung cancer (NSCLC), colorectal cancer (CRC), and head and neck squamous cell carcinoma (HNSCC). Licensed from Akeso, Inc. (HKEX: 9926.HK) for territories including the U.S., Canada, Europe, Japan, Latin America, the Middle East, and Africa. [smmttx.com](https://smmttx.com/pipeline/default.aspx) ## Market Standing - **Valuation/Market Cap**: Approximately $2.7 billion (as of recent data) [linkedin.com](https://www.linkedin.com/company/summit-therapeutics) - **Key Metric**: Annual revenue of approximately $705,000 (reported). The company is pre-commercialization and heavily investing in R&D. Total funding raised since IPO (2015) is not disclosed, but the company has a strong cash position from equity offerings. - **Notable Investors/Partners**: Akeso, Inc. (key licensing partner for ivonescimab). The company is publicly traded with institutional and retail investors. - **Growth Signals**: - Headcount grew 72.5% year-over-year to 244 employees. [linkedin.com](https://www.linkedin.com/company/summit-therapeutics) - Multiple global Phase 3 trials actively recruiting (HARMONi, HARMONi-3, HARMONi-7, HARMONi-GI3, ILLUMINE). - Over 4,000 patients have been treated with ivonescimab across all clinical trials globally. [smmttx.com](https://smmttx.com/pipeline/default.aspx) - Achieved Great Place to Work® Certification. [smmttx.com](https://smmttx.com/careers/careers-overview/default.aspx) ## Competitive Advantages - **Novel Mechanism**: Ivonescimab is a first-in-class bispecific antibody targeting both PD-1 and VEGF simultaneously, potentially offering superior efficacy and fewer side effects compared to combination therapies. - **Speed and Execution**: The company emphasizes "high-speed execution in commercialization" and has rapidly initiated multiple Phase 3 trials. - **Global Reach**: Licensed territories cover major markets (U.S., Canada, Europe, Japan, Latin America, Middle East, Africa) with a strong partner (Akeso) in the rest of the world. - **Strong Balance Sheet**: With a $2.7B market cap and public listing, the company has access to capital markets to fund its pipeline. ## Strategic Focus - **Current priorities**: Advancing ivonescimab through Phase 3 clinical trials across multiple solid tumor indications (NSCLC, CRC, HNSCC), with the goal of regulatory approval and commercialization. - **Future direction**: Expanding the pipeline into additional solid tumors and leveraging the bispecific platform for future therapies. The company is focused on becoming a leading oncology player. - **Near-term milestones**: Data readouts from ongoing Phase 3 trials, potential regulatory submissions, and building commercial infrastructure. ## Why Work Here - **Culture**: The company has achieved Great Place to Work® Certification, indicating a positive, supportive, and fulfilling work environment. Core values include Commitment to People, Integrity, Passion for Excellence, Purposeful Urgency, Accountability, and Collaboration. [smmttx.com](https://smmttx.com/careers/careers-overview/default.aspx) - **Work Environment**: Fast-paced, high-energy atmosphere focused on innovation and collaboration. The company emphasizes "making a significant difference in patients’ lives." - **Benefits (U.S.)**: - 401(k) with 6% employer match - Employee Stock Purchase Plan (ESPP) with 15% discount up to the annual federal limit - Flexible Spending Account - Commuter Benefit - Onsite lunch provided - **Benefits (U.K.)**: - Private Medical Insurance - Employee Assistance Program - Life Assurance Policy - Company Pension Contributions - ESPP - **Remote/Hybrid Policy**: Not explicitly stated, but multiple office locations suggest a hybrid or on-site presence is expected for many roles. - **Open Roles**: 25 active job postings (as of recent data) including Senior Director of Sales Operations, Clinical Scientists, Medical Science Liaisons, and Drug Product MSAT roles. [greenhouse.io](https://job-boards.greenhouse.io/summitherrapeutics) - **Headcount Growth**: 72.5% year-over-year growth signals a scaling organization with opportunities for career advancement. ## Sources 1. [smmttx.com - About Us](https://smmttx.com/company/about-us/default.aspx) 2. [smmttx.com - Investor Relations Overview](https://www.smmttx.com/overview/default.aspx) 3. [smmttx.com - Pipeline](https://smmttx.com/pipeline/default.aspx) 4. [smmttx.com - Careers Overview](https://smmttx.com/careers/careers-overview/default.aspx) 5. [linkedin.com - Summit Therapeutics Company Page](https://www.linkedin.com/company/summit-therapeutics) 6. [greenhouse.io - Summit Therapeutics Careers](https://job-boards.greenhouse.io/summitherrapeutics) ## Other roles at Summit Therapeutics - [Senior Principal Scientist](https://feeny.ai/job/senior-principal-scientist-summit-therapeutics-palo-alto-n0strqh510r6) — Palo Alto, CA - [Director, Sourcing & Procurement - R&D Clinical Operations and Supplies](https://feeny.ai/job/director-sourcing-procurement-r-d-clinical-operations-and-supplies-summit-1ctpcgpnyv4w) — United States - [Associate Director, Clinical Supply Management](https://feeny.ai/job/associate-director-clinical-supply-management-summit-therapeutics-princeton-nj-mvc6azpxcvpd) — Princeton NJ US and Palo Alto CA, United States - [Regional Marketing Director](https://feeny.ai/job/regional-marketing-director-summit-therapeutics-princeton-p443zfx10fsb) — Princeton, NJ - [Director, Clinical Scientist](https://feeny.ai/job/director-clinical-scientist-summit-therapeutics-united-states-4b7fcrb9mkfb) — United States - [Senior Medical Director](https://feeny.ai/job/senior-medical-director-summit-therapeutics-united-states-6d943xf75bpx) — United States - [Senior Director, Oncology Clinical Educators](https://feeny.ai/job/senior-director-oncology-clinical-educators-summit-therapeutics-field-8pyx53adkr7g) — Field, United States - [Director, Clinical Operations Analytics & Performance Excellence](https://feeny.ai/job/director-clinical-operations-analytics-performance-excellence-summit-wqz1bgajvnrd) - [Corporate Counsel, Clinical Contracts](https://feeny.ai/job/corporate-counsel-clinical-contracts-summit-therapeutics-united-states-kr3cyb13nj9c) — United States - [Associate Director, Medical Writing](https://feeny.ai/job/associate-director-medical-writing-summit-therapeutics-remote-gq102xpjcf7z)