--- title: 'Associate Director, Facilities and Engineering at Replimune' canonical: 'https://feeny.ai/job/associate-director-facilities-and-engineering-replimune-milton-park-66qfyefd78es' type: 'job' last_seen: '2026-10-14' --- # Associate Director, Facilities and Engineering at Replimune - **Company:** Replimune - **Location:** Milton Park - **Employment:** full-time - **Work type:** onsite - **Posted:** 2026-10-02 - **Last confirmed live:** 2026-10-14 - **Apply:** https://jobs.ashbyhq.com/replimune/39b51c02-31e2-4111-93d2-ddcd266dab6d ## Job description ## Overview Replimune’s mission is to revolutionize cancer treatment with therapies designed to activate a powerful and durable full-body anti-tumor response, boldly transforming cancer care because patient’s lives depend on it. At Replimune, we live by our values: United: We Collaborate for a Common Goal. Audacious: We Are Bold. Dedicated: We Give Our Full Commitment. Candid: We Are Honest With Each Other. People are at the center of everything we do, and when it comes to our employees, we make it personal. With a deep sense of purpose, a strong and evolving culture, a competitive and forward-looking total rewards program, everyone at Replimune has a unique opportunity to impact on the lives of patients, caregivers and themselves. Join us, as we reshape the future. Summary of job description: The Associate Director, Facilities and Engineering is responsible for the routine management of the Facilities Department at the Milton Park site. The Facilities Department is responsible for ensuring all equipment and utilities are operating as required to support domestic, cGMP and general laboratory operations. The Department manages all building systems (e.g., Monitoring systems, security, alarms and HVAC), coordinates further third party / remote support e.g., Site cleaning, I.T, telephone, data management. This position is based in our Milton Park location and typically has a 5-day on-site expectation. Key responsibilities: - Responsible for supervision and organization of the Facilities Department, consisting of Facilities Engineering, Maintenance and Calibration. - Responsible for operation and maintenance of all utilities and systems required to support general operations, including associated cGMP documentation as required. - Responsible for the maintenance and calibration of all equipment and systems, coordinating works to agreed schedules. - Close liaison with Framingham Facilities Senior Manager/management to align Facilities practices, processes and insights across Framingham and Milton Park sites - Maintenance of Facilities documentation systems, including, equipment files, calibration files, etc. in a cGMP compliant manner. - Ensure functional input into cGMP investigations, CAPA’s and Change Controls driving delivery in line with Site QMS targets. - Ensure the function is always cGMP Audit ready. Support Facilities function in audits as an SME. - Coordinate, oversee and review work performed by external or third-party contractors including project management and the issue of work permits. - Responsible for waste management including chemical and biological waste, trade effluent and in particular documenting the safe disposal of waste containing, or potentially containing, GMO’s or live viral material. Completion of duty of care audits for waste management. - Support site Health and Safety (IOSH Managing Safely or NEBOSH NGC trained). Serve as Facility Emergency Coordinator / Safety Contact. - Manage the site call out team, out of hours response and business continuity plan. - Maintaining Facilities KPIs and SLA’s - Responsibility for line management and development of the Facilities team - Provide input into facilities budget planning and OPEX. Other responsibilities - Deputise for Director as required (during absences or representation at meetings) - Serve as Replimune liaison / contact with the landlord, local authorities, utilities, and general service providers etc. - Act as a key contact for coordination of general site communications and support for the Social Committee activities. - Define and manage projects, assisting Engineering contractors with design, installation, and modification of equipment / utilities with review and approval of any project documentation and reports. - Represent Facilities at inter-departmental meetings and interact with external vendors, as necessary. - Other tasks as assigned. Educational requirements: - A BA or BSc in Engineering, Science, or equivalent related discipline. Experience and skill requirement: - Minimum 4 years building management experience in a relevant work (cGMP experience preferred) environment. - Minimum 1-year demonstrable experience in line management and development of individuals and teams - Field experience in building management systems, HVAC, refrigeration, plumbing. Experience of managing electrical safety including periodic inspection, PAT testing and Lockout/Tagout procedures, Health and Safety and acting as Fire Safety Manager - cGMP training and documentation experience - Experience with biological and chemical waste management - Experience with Asset management software (Blue Mountain or similar). - Demonstrated experience operating in highly cross-functional environments; ability to build relationships at all levels across the organization. - Good communication and organization skills - Computer literacy (MS Word, MS Excel, Outlook, etc.). ## About Replimune Replimune Group, Inc., headquartered in Woburn, MA, was founded in 2015 with the mission to transform cancer treatment by pioneering the development of a novel portfolio of oncolytic immunotherapies. Replimune’s proprietary RPx platform is based on a potent HSV-1 backbone intended to maximize immunogenic cell death and the induction of a systemic anti-tumor immune response. The RPx platform is designed to have a unique dual local and systemic activity consisting of direct selective virus-mediated killing of the tumor resulting in the release of tumor derived antigens and altering of the tumor microenvironment to ignite a strong and durable systemic response. The RPx product candidates are expected to be synergistic with most established and experimental cancer treatment modalities, leading to the versatility to be developed alone or combined with a variety of other treatment options. For more information, please visit [www.replimune.com](http://www.replimune.com). We are an Equal Opportunity Employer. ## About Replimune ## Company Overview - **One-liner**: Replimune is a clinical-stage biotech company focused on revolutionizing cancer treatment with a new class of oncolytic immunotherapies intended to activate a powerful and durable full-body anti-tumor response. - **Entity Type**: Public (ticker not explicitly provided in search results, but company is publicly traded) - **Headquarters**: Framingham, Massachusetts, USA (with additional locations in Woburn, MA and Oxfordshire, UK) - **Founded**: 2015 - **Founders**: Robert Coffin, Ph.D. (Founder and Chief Scientist) ## Core Business - **Primary industry**: Biotechnology – oncology, oncolytic immunotherapy - **Target customers**: B2B (pharmaceutical partners) and ultimately patients through healthcare providers - **Mission**: To ignite a systemic immune response to cancer and reshape the future of cancer care ## Products & Services - **RPx Platform**: Proprietary, next-generation HSV-1-based oncolytic immunotherapy platform that powers all pipeline candidates. - **RP1**: Investigational oncolytic immunotherapy for advanced melanoma (IGNYTE trial, PDUFA date April 10, 2026) and non-melanoma skin cancers; also being studied as monotherapy in organ transplant patients with skin cancer (ARTACUS trial). - **RP2**: Investigational oncolytic immunotherapy for metastatic uveal melanoma (Phase 2/3 RP2-202 trial) and hepatocellular carcinoma (Phase 2 in combination with atezolizumab/bevacizumab). ## Market Standing - **Valuation/Market Cap**: Not publicly available in provided sources - **Key Metric**: Clinical-stage; no approved products yet. Key regulatory milestone: FDA action date for RP1 in advanced melanoma on April 10, 2026. - **Notable Partners**: Bristol-Myers Squibb (supply of nivolumab), Roche (supply of atezolizumab and bevacizumab) – Replimune retains full commercial rights. - **Growth Signals**: Completed enrollment in IGNYTE trial; confirmatory IGNYTE-3 trial underway; own 63,000 sq ft U.S. manufacturing facility in Woburn, MA enabling global commercial supply; broad pipeline across multiple solid tumor indications. ## Competitive Advantages - **Strong IP position**: Wholly-owned, unencumbered RPx platform with broad patent protection. - **In-house manufacturing**: Dedicated U.S. facility for commercial-scale production, reducing reliance on contract manufacturers. - **First-mover potential**: Poised to be one of the first oncolytic immunotherapies to reach the market if RP1 gains FDA approval. - **Full rights retained**: All partnership agreements allow Replimune to keep full commercial rights to its therapies. ## Strategic Focus - Advancing RP1 toward FDA approval in advanced melanoma (April 2026 PDUFA date) - Expanding pipeline into additional indications (uveal melanoma, hepatocellular carcinoma, non-melanoma skin cancers) - Building out commercial infrastructure and manufacturing capabilities - Exploring combination therapies with checkpoint inhibitors (nivolumab, atezolizumab) ## Why Work Here - **Culture**: Cross-functional, collaborative, values-driven environment. Employee survey results show 92% proud to work at Replimune, 88% feel they make a positive difference, 78% would recommend the company. - **Flexibility**: Hybrid and remote work options available depending on role; home office and mobile phone stipend provided. - **Compensation**: New hire equity grants, generous annual bonus plans, retirement plans with substantial company match (100% vested from day one). - **Benefits**: Medical, dental, and vision insurance 100% paid by the company. - **Locations**: U.S. (Woburn, MA and Framingham, MA) and UK (Oxfordshire) – opportunities to work across both sites. ## Sources 1. [Replimune Homepage](https://www.replimune.com/) 2. [Replimune Careers](https://www.replimune.com/careers) 3. [Replimune About Us](https://www.replimune.com/about-us) 4. [Replimune Team](https://www.replimune.com/team) 5. [Replimune Pipeline](https://www.replimune.com/pipeline) ## Other roles at Replimune - [Associate Director, Process Development](https://feeny.ai/job/associate-director-process-development-replimune-milton-park-pz1973yzc4jf) — Milton Park - [Senior Engineer, Technical Operations](https://feeny.ai/job/senior-engineer-technical-operations-replimune-framingham-hbhptbrvyq18) — Framingham, MA - [Senior Associate, Clinical Supply Chain](https://feeny.ai/job/senior-associate-clinical-supply-chain-replimune-framingham-0g0qt53fy3ma) — Framingham, MA - [Director, Data Analytics and Reporting](https://feeny.ai/job/director-data-analytics-and-reporting-replimune-woburn-ex67n99bnkky) — Woburn, MA - [Validation Engineer II](https://feeny.ai/job/validation-engineer-ii-replimune-framingham-g9ccc3qravmk) — Framingham, MA - [Senior Quality Control Analyst](https://feeny.ai/job/senior-quality-control-analyst-replimune-milton-park-fem77bn1grad) — Milton Park - [Quality Control Analyst I](https://feeny.ai/job/quality-control-analyst-i-replimune-milton-park-gsyw4st58cnw) — Milton Park - [QC Microbiology Technician](https://feeny.ai/job/qc-microbiology-technician-replimune-framingham-nxknzm2vk893) — Framingham, MA - [Senior Quality Control, Microbiology Analyst](https://feeny.ai/job/senior-quality-control-microbiology-analyst-replimune-framingham-vpvxm0nj5h9a) — Framingham, MA - [Director, Medical Publications and Scientific Communication](https://feeny.ai/job/director-medical-publications-and-scientific-communication-replimune-woburn-2x89896ezvf6) — Woburn, MA