--- title: 'Associate Director, Supply Chain & Logistics at Atrium Therapeutics' canonical: 'https://feeny.ai/job/associate-director-supply-chain-logistics-atrium-therapeutics-san-diego-31w7rn8e081j' type: 'job' last_seen: '2026-09-11' --- # Associate Director, Supply Chain & Logistics at Atrium Therapeutics - **Company:** Atrium Therapeutics - **Location:** San Diego, CA - **Employment:** full-time - **Work type:** remote - **Posted:** 2026-09-10 - **Last confirmed live:** 2026-09-11 - **Apply:** https://jobs.lever.co/atrium-therapeutics/ee629186-c6e5-4cf2-885a-e0058b35ed79 ## Job description Atrium is a biopharmaceutical company pioneering delivery of RNA therapeutics to the heart to transform the standard of care for people living with cardiomyopathies. Our proprietary technology leverages the targeted RNA delivery platform initially designed at Avidity, which combines the tissue selectivity of mAbs and other targeted delivery ligands with the precision of oligonucleotides. This unique combination is designed to allow selective targeting of the underlying genetic drivers of disease that were previously undruggable. Through targeted, non-viral delivery of siRNA to cardiac tissues, our approach has the potential to overcome key limitations of nonspecific viral and nanoparticle-based delivery systems, including challenges related to tissue specificity, immunogenicity, and redosing. Job Summary: Atrium Therapeutics is seeking an experienced Associate Director, Clinical Supply Chain & Logistics to manage the end-to-end planning, execution, and oversight of clinical trial material supply for Atrium's cardiomyopathy programs. This role owns clinical supply forecasting, packaging and labeling, IRT/RTSM configuration, depot vendor management and distribution, and has an expanded scope to include responsibility for shipping and logistics operations — including carrier and freight-forwarder management, import/export and customs compliance, cold-chain shipment coordination and execution for Atrium Technical Operations and other teams. The role partners closely with Clinical Operations, Quality, Technical Operation, Regulatory, and external CMO/3PL partners to ensure uninterrupted, compliant, and on-time drug supply. Level of hire (Senior Manager vs. Associate Director) will be determined based on the selected candidate's experience. Job Responsibilities: •Provide strategic direction for clinical supply strategies by translating and integrating trial designs, enrollment assumptions, manufacturing readiness and regulatory requirements into actionable clinical supply plans. •Manage IRT/RTSM vendor and lead specification gathering, user acceptance testing and IRT lifecycle throughout study duration, ensuring accurate randomization, resupply, and inventory levels across studies and sites. •Identify and mitigate clinical supply risks (e.g., expiry, demand variability, single-source dependencies) and build contingency plans to prevent trial disruptions. •Partner with Clinical Operations, CMC, Regulatory Affairs, and Quality to align clinical supply timelines with study start-up, enrollment, and closeout milestones. •Oversee and coordinate packaging, labeling (including label design and label proof development), distribution and return drug management activities with CMOs according to approved budgets and plans. •Represent Clinical Supply Chain in cross-functional Clinical Study Team, CRO and vendor meetings. •Authors pharmacy manuals and participates in reviews of other study related documentation •Serve as the primary point of accountability for shipping and logistics requests across Technical Operations, Development Sciences, Biology and Chemistry teams, including transfers of GMP and non-GMP materials (intermediates, drug substance, drug product, testing samples etc.) •Manage relationships with couriers, freight forwarders, and specialty cold-chain carriers •Own import/export compliance, including licenses, permits, customs documentation, and country-specific import requirements for material shipments. •Oversee cold-chain and temperature-controlled shipment execution, including packaging qualification, temperature excursion investigation, and corrective action. •Monitor shipment status end-to-end, coordinate with vendors on inbound/outbound logistics, proactively resolve delays or exceptions, and maintain shipment tracking and reporting for cross-functional stakeholders. •Ensure all clinical supply and logistics activities comply with GMP, GCP, and applicable import/export regulations. •Maintain inspection-ready documentation and ensure clinical supply and shipping records are filed appropriately in the eTMF/quality systems. •Support the creation and revision of SOPs related to clinical supply chain and logistics processes. •Lead or contribute to deviation, CAPA, and investigation processes related to supply or shipping issues (e.g., temperature excursions, shipment delays or damage). Education & Experience Requirements: •Bachelor's degree in life sciences, supply chain, logistics, or a related field required; advanced degree preferred. •Associate Director: typically 10+ years, of clinical supply chain experience in biotech/pharma, with direct experience in packaging, labeling, and distribution of investigational products through all stages of international clinical studies (start-up, enrollment, maintenance and close-out) •Demonstrated experience managing shipping, logistics, or distribution operations, including carrier/freight-forwarder management and import/export or customs compliance. •Experience with IRT/RTSM systems, clinical supply forecasting tools, and CMO/depot network management. •Experience in rare disease, cardiology, or genetic medicine clinical trials is a plus. •Working knowledge of GMP, GCP, and global import/export regulations relevant to clinical trial materials. •Strong vendor management, negotiation, and cross-functional collaboration skills. •Ability to manage multiple competing priorities in a fast-paced, growing biotech environment. •Excellent analytical, organizational, and written/verbal communication skills. •Comfort operating with the autonomy and hands-on scope typical of a small, growing company. •Some domestic and/or international travel may be required to support vendor, depot, or CMO site visits. •This role is based in San Diego, CA or Remote What We Provide: •The base salary range for this role is $180,500-$199,500. The final compensation will be commensurate with such factors as relevant experience, skillset, internal equity and market factors. •Atrium offers competitive compensation and benefits which include stock options & RSUs, as well as a 401(k) with an employer match. In addition, the comprehensive wellness program includes coverage for medical, dental, vision, LTD, and unlimited of time off including summer & winter breaks. •A commitment to learning and development which includes a variety of programming internally developed by and for Atrium employees, opportunities for job-specific training offered by industry, and an education reimbursement program. ## About Atrium Therapeutics ## Company Overview - **One-liner**: Atrium Therapeutics is a biopharmaceutical company pioneering the delivery of RNA therapeutics directly to the heart muscle to transform the standard of care for people living with cardiomyopathies. - **Entity Type**: Private (startup stage, not yet publicly traded; no funding rounds publicly disclosed) - **Headquarters**: San Diego, California, United States - **Founded**: 2026 - **Founders**: Not explicitly listed; the company was formed by a team of former executives from Avidity Biosciences and other biotech firms, led by CEO Kathleen Gallagher. ## Core Business - **Primary industry**: Biotechnology – RNA therapeutics for cardiovascular diseases (precision cardiology). - **Target customers**: Patients with rare cardiomyopathies (PLN cardiomyopathy, PRKAG2 syndrome), healthcare providers, and payers (B2B/B2C through drug development and eventual commercialization). - **Mission statement**: “Pioneer the delivery of RNA therapeutics to the heart to transform the standard of care for people living with cardiomyopathies.” ## Products & Services - **ATR 1072**: Development candidate for PRKAG2 syndrome (rare cardiomyopathy). Preclinical/early clinical stage. - **ATR 1086**: Development candidate for PLN (phospholamban) cardiomyopathy. Preclinical/early clinical stage. - **Undisclosed pipeline**: Two additional research-stage targets in rare cardiomyopathies. - **Technology Platform**: Proprietary RNA delivery platform based on the clinically validated AOC (Antibody-Oligonucleotide Conjugate) technology, originally designed at Avidity Biosciences. Combines the tissue selectivity of monoclonal antibodies with the precision of oligonucleotides to deliver siRNA directly to cardiac tissue, overcoming challenges with immunogenicity, cytotoxicity, and redosing limitations. ## Market Standing - **Valuation/Market Cap**: Not disclosed (private company; no public funding rounds reported). - **Key Metric**: Headcount of 41 employees (as of mid-2026), with 5.7% monthly growth; 28 employees recruited from Avidity Biosciences. - **Notable Investors/Partners**: No specific investors or partnerships disclosed publicly. The company’s “Investors” page is a placeholder. - **Growth Signals**: Founded in 2026; rapid team building with deep expertise from Avidity, Ionis, Biogen, etc.; two lead candidates in development for high‑unmet‑need cardiomyopathies; 4,200+ LinkedIn followers with +4.2% monthly growth. ## Competitive Advantages - **Proprietary cardiac RNA delivery platform** that targets heart muscle with high specificity – a key differentiator from viral and nanoparticle delivery systems. - **Clinically validated technology** originally developed at Avidity Biosciences, reducing technical risk. - **Focus on underserved rare cardiomyopathies** with no approved therapies (PLN, PRKAG2), offering potential for rapid regulatory pathways (orphan drug designation). - **Experienced leadership team** with track record in RNA therapeutics, rare disease drug development, and commercialization (Akcea, Ionis, Biogen, Avidity). ## Strategic Focus - **Advance two lead candidates** (ATR 1072, ATR 1086) through preclinical and into clinical trials. - **Expand the pipeline** with additional undisclosed targets in rare cardiomyopathies. - **Build out the organization**, particularly in translational medicine, process development, and quality assurance (as evidenced by current job postings). - **Leverage the AOC platform** to potentially address broader cardiac indications beyond the initial rare disease focus. ## Why Work Here - **Cutting‑edge science**: Opportunity to work on a novel RNA delivery platform with the potential to transform cardiology. - **Small, agile team** (~41 employees) allows for high impact and visibility across functions. - **Founding team from Avidity Biosciences** brings deep domain expertise and a proven track record in RNA therapeutics. - **Location**: Onsite roles in San Diego, California (Science Center Drive), a major biotech hub. - **Current open roles** include: - Scientist II, Translational Medicine (San Diego, onsite) - Senior Director, AOC Process Development & Manufacturing – Oligonucleotide (San Diego) - Senior Director, Head of Quality Assurance (San Diego) - Manager, Accounting (from LinkedIn) - **Culture**: The company’s website emphasizes a commitment to patients with high unmet need, a collaborative environment, and a passion for precision medicine. - **Perks**: Not explicitly stated, but typical biotech early‑stage includes equity, competitive compensation, and the chance to shape a young company’s culture. ## Sources 1. [Atrium Therapeutics - Homepage](https://atriumtherapeutics.com/) 2. [Atrium Therapeutics - About Page](https://atriumtherapeutics.com/about/) 3. [Atrium Therapeutics - Investors Page](https://investors.atriumtherapeutics.com/overview) 4. [Atrium Therapeutics - Careers Page](https://atriumtherapeutics.com/careers/) 5. [LinkedIn - Atrium Therapeutics](https://www.linkedin.com/company/atrium-therapeutics) ## Other roles at Atrium Therapeutics - [Manager, Development Sciences Operations](https://feeny.ai/job/manager-development-sciences-operations-atrium-therapeutics-san-diego-fkc4aevv610b) — San Diego, CA - [Research Associate (Contract)](https://feeny.ai/job/research-associate-contract-atrium-therapeutics-san-diego-84w1pwtnp1nq) — San Diego, CA - [Associate Director, Translational Medicine](https://feeny.ai/job/associate-director-translational-medicine-atrium-therapeutics-san-diego-ct34y2jzjtwy) — San Diego, CA