---
title: 'Associate Medical Director/Medical Director at Iambic Therapeutics, Inc'
canonical: 'https://feeny.ai/job/associate-medical-director-medical-director-iambic-therapeutics-inc-united-nrtdmj0ywpmb'
type: 'job'
last_seen: '2026-09-16'
---

# Associate Medical Director/Medical Director at Iambic Therapeutics, Inc

- **Company:** Iambic Therapeutics, Inc
- **Location:** United States
- **Employment:** full-time
- **Work type:** remote
- **Posted:** 2026-09-10
- **Last confirmed live:** 2026-09-16
- **Apply:** https://jobs.ashbyhq.com/iambic-therapeutics/9b157470-f64e-4416-ad7f-4b68b9db77b1

## Job description

## JOB SUMMARY

Iambic Therapeutics is seeking an Associate Medical Director or Medical Director to join its growing Clinical Development team. This position will be responsible for study execution and oversight of a clinical program currently in phase 1, as well as supporting pipeline programs that are in the preparation phase for IND submission. In addition to providing medical oversight for the phase 1 clinical trial, ensuring patient safety, regulatory compliance and scientific integrity, this individual will also contribute to the clinical program strategy and execution.

## KEY RESPONSIBILITIES

- Serve as the medical monitor for assigned clinical trials, providing medical and scientific expertise throughout the study lifecycle.
- Work closely with other functional areas within Research and Development (clinical operations, regulatory sciences, data management, biostatistics, clinical pharmacology, nonclinical) to facilitate the execution of clinical trials and ensure that high standards of study conduct are met
- Ensure participant safety by reviewing adverse events (AEs), serious adverse events (SAEs) and protocol deviations collaborate with pharmacovigilance to assess safety signals across the study
- Provide guidance on patient eligibility and protocol adherence
- Contribute to preparation of study-related documents including study protocols and amendments, Investigator Brochures (IBs), informed consent forms (ICFs), and clinical study reports (CSRs)
- Review and interpret clinical trial data, ensuring accuracy and consistency in the safety, efficacy and other data
- Support interactions with regulatory agencies, including preparation of documents for submission and participation at regulatory meetings
- Establish strategic partnerships with KOLs, centers of excellence, and patient advocacy organizations
- Develop content for advisory board meetings
- Prepare abstracts and presentations for scientific symposia and manuscripts for publication in high impact peer reviewed journals
- Keep up to date on standard of care and experimental therapies in relevant clinical areas through familiarity with literature, attendance at meetings, conventions and professional associations

## QUALIFICATIONS

- MD or PharmD with clinical oncology experience as well as experience in biotech/pharma oncology drug development is preferred. PhD with a minimum of 3 years of biotech or pharmaceutical experience in oncology drug development.
- Experience as a medical monitor on a clinical trial, including patient eligibility review, site interaction to oversee protocol adherence, protocol deviation review, clinical data review and cleaning activities, coding
- Experience in executing on clinical studies, including interactions with regulatory agencies
- Excellent written and verbal communication skills
- Ability to work effectively in cross functional teams with internal and external partners
- Excellent organizational and time management skills with strong attention to detail, and proven ability to handle multiple tasks efficiently and effectively.
- Creative problem-solving skills with proven ability to act in a proactive manner

## ABOUT IAMBIC THERAPEUTICS

Iambic is a clinical-stage life-science and technology company developing novel medicines using its AI-driven discovery and development platform. Based in San Diego and founded in 2020, Iambic has assembled a world-class team that unites pioneering AI experts and experienced drug hunters. The Iambic platform has demonstrated delivery of new drug candidates to human clinical trials with unprecedented speed and across multiple target classes and mechanisms of action. Iambic is advancing a pipeline of potential best-in-class and first-in-class clinical assets, both internally and in partnership, to address urgent unmet patient need. Learn more about the Iambic team, platform, pipeline, and partnerships at [iambic.ai](http://iambic.ai).

## MISSION & CORE VALUES

Our mission is to deliver better medicines through innovations in AI-based discovery technologies. The culture and work at Iambic Therapeutics are profoundly strengthened by the diversity of our people and our differences in background, culture, national origin, religion, sexual orientation, and life experiences. We are committed to building an inclusive environment where a diverse group of talented humans work together to discover therapeutics and create technologies.

## PAY AND BENEFITS

We offer industry leading competitive pay, company paid healthcare, flexible spending accounts, voluntary life insurance, 401K matching, and uncapped vacation to our team. We are in a brand-new state-of-the art facility in beautiful San Diego with an onsite gym, dining, and easy access to great places to live and play.

## About Iambic Therapeutics, Inc

## Company Overview

- **One-liner**: Iambic Therapeutics is a clinical‑stage biotechnology company that uses an AI‑driven platform to discover and develop novel small‑molecule medicines for oncology and other diseases.  
- **Entity Type**: Private (late‑stage venture‑backed)  
- **Headquarters**: San Diego, California, United States  
- **Founded**: 2020  
- **Founders**: Not explicitly named in available sources; leadership includes a Co‑Founder & CEO and a Co‑Founder & CTO.  

## Core Business

- **Primary industries**: Biotechnology, AI‑powered drug discovery, oncology therapeutics  
- **Target customers**: B2B partnerships with pharmaceutical companies (e.g., Bayer) and, ultimately, patients through a wholly‑owned pipeline of clinical‑stage candidates  
- **Mission**: *“Better technology for better medicines”* – using machine learning and automation to transform the creation of new therapeutics  

## Products & Services

- **Enchant Platform**: A multi‑modal transformer AI that breaks down data barriers between preclinical and clinical R&D, enabling rapid molecular design.  
- **NeuralPLexer**: A co‑folding AI technology that predicts protein‑ligand structures to guide drug design.  
- **Automated High‑Throughput Experimentation**: AI‑driven robotics that generate new biological data from novel molecular designs on a weekly cadence.  
- **IAM1363** (HER2 inhibitor): A highly selective, brain‑penetrant tyrosine kinase inhibitor for HER2‑driven cancers; currently in Phase 1b clinical studies.  
- **IAM‑C1** (CDK2/4 dual inhibitor): A potential first‑in‑class selective inhibitor for HR+/HER2‑ metastatic breast cancer (preclinical).  
- **IAM‑K1** (KIF18A inhibitor): A potential best‑in‑class allosteric inhibitor for triple‑negative breast cancer, ovarian cancer, and other solid tumors (preclinical).  
- **Undisclosed programs**: Additional wholly‑owned candidates across multiple target classes and mechanisms.  

## Market Standing

- **Valuation**: Not publicly disclosed  
- **Key Metric**: **Total funding** – $330.8 M (including a $100 M Series B in Oct 2023, a $50 M Series B extension in Apr 2024 led by EXOR N.V. and Mubadala Capital, and a $127.8 M venture round in Nov 2025)  
- **Notable Investors/Partners**: EXOR N.V., Mubadala Capital, Nexus Venture, Bayer (collaboration in AI drug discovery), and a Scientific Advisory Board including Nobel Laureate Frances Arnold (Caltech)  
- **Growth Signals**:  
  - Headcount of **117** (64.5 % year‑over‑year growth)  
  - Active job postings: **18** (+200 % quarterly, +50 % yearly)  
  - Pipeline advanced from program launch to IND in **2 years** (vs. 6‑year industry average for IAM1363)  
  - Broad platform applicability demonstrated across orthosteric, allosteric, and protein‑protein interaction modalities  

## Competitive Advantages

- **Speed**: AI‑driven platform can deliver development candidates to clinical trials in roughly one‑third the industry average time.  
- **Selectivity & Differentiated Profiles**: IAM1363 shows > 5000‑fold selectivity against EGFR, avoiding EGFR‑driven toxicity; IAM‑C1 targets CDK2/4 with a novel selectivity profile.  
- **Broad Platform Applicability**: Platform has produced leads across diverse protein classes and mechanisms (orthosteric, allosteric, PPI modulators).  
- **Integration of AI and Drug Hunting**: Tightly integrated team of AI experts and seasoned drug hunters, with a culture of “audacity” that tackles hard chemistry problems.  

## Strategic Focus

- Advancing the clinical pipeline: IAM1363 Phase 1b, preparing IAM‑C1 and IAM‑K1 for IND‑enabling studies.  
- Expanding platform partnerships (e.g., Bayer collaboration).  
- Scaling the organization: actively hiring in ML science, computational chemistry, medicinal chemistry, and clinical operations.  
- Exploring new therapeutic areas and target classes through the Enchant and NeuralPLexer technologies.  

## Why Work Here

- **Culture**: Values of **Respect**, **Collaboration**, and **Audacity** – cross‑functional teamwork with resilience and optimism; a flat, high‑trust environment.  
- **Work Model**: Based in La Jolla/San Diego, CA; the company emphasizes on‑site collaboration for drug‑discovery and lab‑based roles; remote/hybrid policy not explicitly stated.  
- **Team Growth**: Rapidly scaling (headcount +64 % YoY) with a strong pipeline of open roles in ML, computational chemistry, drug product development, and clinical operations.  
- **Cutting‑Edge Work**: Opportunity to work at the intersection of frontier AI (large multimodal models, agentic data pipelines) and real‑world drug discovery that reaches patients.  
- **Leadership & Mentorship**: Advisory board includes Nobel laureate and former NVIDIA AI director; close integration of AI and biology.  

## Sources

1. [iambic.ai](https://www.iambic.ai/) – Homepage, platform, and corporate overview  
2. [iambic.ai/about](https://www.iambic.ai/about) – Leadership, advisory board, investors  
3. [iambic.ai/pipeline](https://www.iambic.ai/pipeline) – Pipeline details (IAM1363, IAM‑C1, IAM‑K1)  
4. [iambic.ai/careers](https://www.iambic.ai/careers) – Careers page, values, open positions  
5. [linkedin.com/company/iambic-ai](https://www.linkedin.com/company/iambic-ai) – Company stats (headcount 117, $3.4M revenue, $330.8M funding, funding rounds, employee growth)

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