--- title: 'Associate Scientist at Flagship Pioneering, Inc.' canonical: 'https://feeny.ai/job/associate-scientist-flagship-pioneering-inc-cambridge-7pz157j2yvh5' type: 'job' last_seen: '2026-09-11' --- # Associate Scientist at Flagship Pioneering, Inc. - **Company:** Flagship Pioneering, Inc. - **Location:** Cambridge, MA - **Posted:** 2026-09-08 - **Last confirmed live:** 2026-09-11 - **Apply:** https://boards.greenhouse.io/flagshippioneeringinc/jobs/8786215002?gh_jid=8786215002 ## Job description Position Summary: Quotient is seeking an Associate Scientist with experience in molecular biology, immunology and early drug discovery. This position will contribute to the translational validation of discovery platform targets in mechanistic and disease-relevant pharmacological models. The ideal candidate will be a talented, goal-oriented and highly motivated individual who will play a vital role in progressing the company’s early discovery projects in inflammatory and autoimmune diseases. They will have a strong background in developing complex immune assays with primary human cells and tissues designed to understand the molecular basis of disease states as well as drug mechanism of action.  The candidate must be comfortable working in and contributing to a diverse, highly dynamic, fast-paced and cross-functional team environment. Responsibilities: - Use insights from literature and experimental results to design, optimize and implement robust in vitro experiments to validate target mechanisms and translational relevance to human disease - Execute biochemical and cell-based assays using recombinant proteins, mammalian cell lines and primary cells to define drug mechanism of action - Utilize creativity and critical thinking skills to innovate, troubleshoot/optimize experiments and to interpret data to drive go/no go decisions - Must display attention to detail, sense of urgency and “outside the box” thinking - Work under the supervision of senior members of the team and assist in designing and implementing research protocols - Perform laboratory experiments and apply various laboratory techniques including compound screens, flow cytometry, ELISA, qPCR, Western blotting. - Conduct in vitro and ex vivo assays, such as but not limited to overexpression, knockdown, knockout on immortalized and primary cells, stimulation, and cytokine profile or functional assays - Collect, analyze and interpret scientific data accurately - Maintain precise experimental records and documentation - Contribute to the preparation of research articles, reports and presentations - Follow lab safety procedures and rules to ensure a safe working environment - Participate in regular team meetings to discuss progress, challenges, and future plans Qualifications: Essential - BS or MS in Immunology, Biochemistry, Molecular Biology, or a related discipline and 3+ years of industry experience for MS or 5+ years for BS - In depth understanding of cellular and molecular biology techniques including mammalian cell culture, transfection, CRISPR, western blots, qPCR, immunofluorescence and flow cytometry - Prior experience running cell-based compound screening assays - Prior experience in an industrial setting, and familiarity with Good Laboratory Practice (GLP) as well as proficiency in the use of Electronic Laboratory Notebooks (ELN) - Experience with experimental design and strong proficiency in assay execution, troubleshooting, data analysis, and data interpretation - Outstanding organizational and record keeping skills - Execution focused, team oriented, and highly motivated Desirable - Proficiency with RNA-seq, cloning and image analysis - Previous experience with lentiviral transductions or AAV transfection/transduction Values and Behaviors: - Encourage respectful disagreement and cultivate open-minded, ego-free interactions to continuously push each other towards excellence - Seek out diverse perspectives; practice active listening and genuine curiosity to ensure all contributions are valued, regardless of source - Recognize the impact of your behavior, language and attitudes, and strive for balanced, meaningful exchanges that enhance mutual growth and understanding in all interactions - Use a company-first mindset to guide decision-making; prioritize team over individual success - Take calculated risks and challenge convention in the quest for exceptional outcomes About Quotient: Quotient Therapeutics is a privately-held, early stage company developing breakthrough medicines informed by natural somatic genetic diversity present in patients. Through our work in somatic genomics, we are forging a new status quo for biopharma research and development across a broad pipeline of internal and partnered programs. The company was founded by Flagship Pioneering, an innovative enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Generate Biomedicines, Sana Biotechnology (SANA), Tessera Therapeutics, Evelo Biosciences (EVLO), Indigo Agriculture, Seres Therapeutics (MCRB), and Syros Pharmaceuticals (SYRS). Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com. The salary range for this role is $96,000 - $126,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Quotient Therapeutics, Inc. currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Quotient Therapeutics, Inc.'s good faith estimate as of the date of publication and may be modified in the future. Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com. ## About Flagship Pioneering, Inc. ## Company Overview - **One-liner**: Flagship Pioneering is a life sciences venture creation firm that conceives, creates, and capitalizes breakthrough bioplatform companies in biotechnology, health, and sustainability. - **Entity Type**: Private (Venture Creation Firm) - **Headquarters**: Cambridge, Massachusetts, United States - **Founded**: 2000 - **Founders**: Noubar Afeyan (Co-Founder & CEO) ## Core Business - **Primary industry/industries**: Biotechnology Research, Life Sciences Venture Creation, Company Incubation - **Target customers**: B2B / B2G – partners with academic institutions, pharma companies, and investors; also acts as an employer for scientists, entrepreneurs, and corporate builders - **Mission or purpose statement**: “To harness the 21st century's most powerful technological forces for good to deliver a better future for all.” ## Products & Services Flagship does not sell products directly; its offerings are the companies it creates and the innovation platform it operates. - **Innovation Platform**: A systematic, institutionalized process to identify “unreasonable” scientific questions, test them rigorously, and spin out independent companies that develop therapeutics, diagnostics, agricultural technologies, and more. - **Portfolio Companies**: Over 120 companies founded, including Moderna, Generate:Biomedicines, Inari Agriculture, Tessera Therapeutics, Lila Sciences, and others. Each is a separate enterprise with its own products (e.g., mRNA vaccines, gene-editing tools, AI-driven drug discovery). ## Market Standing - **Valuation/Market Cap**: Not publicly disclosed (privately held) - **Key Metric**: Annual revenue of approximately $800 million (2025/2026 estimate) and 620 employees (+9.7% YoY growth) - **Notable Investors/Partners**: Flagship is itself an investor and partner; key collaborations include AWS (to accelerate drug discovery), Harvard Medical School, Broad Institute, and multiple top-tier biopharma companies. Portfolio company Moderna is a publicly traded giant. - **Growth Signals**: 78 active job postings (+50% quarterly), recent formation of Terion (digital agriculture infrastructure) and Serif Biomedicines (modified DNA platform), and expanded presence in Europe and Asia. ## Competitive Advantages - **Unique Model**: Combines scientific exploration, company creation, and capital investment under one roof – “a way that is largely without precedent” - **Deep Talent Pool**: Exceptional network of scientist-entrepreneurs and company builders; top hires from MIT, Harvard, Biogen, Novartis, and Pfizer - **Track Record**: Over two decades of founding transformational companies (e.g., Moderna’s COVID‑19 vaccine), demonstrating repeatable innovation - **Process-Driven**: Systematic methodology for turning “what‑if” questions into patentable bioplatforms, reducing risk compared to ad‑hoc startup creation ## Strategic Focus - **Current priorities**: Expanding AI/machine learning integration across drug discovery and life sciences (highlighted by AWS collaboration); entering preemptive health and medicine; advancing sustainable agriculture and climate solutions; growing international operations (UK, Singapore, Canada, Switzerland, Japan) - **Direction for growth**: Launching new platform companies at a steady cadence (e.g., Terion, Serif in 2026); deepening expertise in computational protein design, modified DNA, and gene editing ## Why Work Here - **Culture**: “Brave and bold organization of creative-thinkers with insurgent mindsets” – emphasis on fearlessness, mentorship, and teamwork across science and business - **Work Environment**: Headquarters in Cambridge, MA with 5 US offices; roles span research, strategy, finance, and operations; hybrid/remote flexibility varies by role - **Notable Perks**: Opportunity to work on world-changing science (e.g., COVID‑19 vaccine, gene editing) alongside top scientists and company builders; strong compensation (salary range example: Sr. Associate ~$68K, ML Engineer ~$122K; overall comp rating 3.7/5) - **Engineering/Science Culture**: Heavy investment in R&D (15% of workforce in research), cutting-edge tools (Cryo‑EM, AI/ML), and a process that encourages bold leaps ## Sources 1. [flagshippioneering.com](https://www.flagshippioneering.com/) 2. [flagshippioneering.com/about](https://www.flagshippioneering.com/about) 3. [flagshippioneering.com/join](https://www.flagshippioneering.com/join) 4. [flagshippioneering.com/join/roles](https://www.flagshippioneering.com/join/roles) 5. [linkedin.com/company/flagship-pioneering](https://www.linkedin.com/company/flagship-pioneering) ## Other roles at Flagship Pioneering, Inc. - [Senior UAS Systems Integration Engineer II](https://feeny.ai/job/senior-uas-systems-integration-engineer-ii-flagship-pioneering-inc-boulder-dd2xmqp6d98b) — Boulder, CO - [Senior Director, Business Development](https://feeny.ai/job/senior-director-business-development-flagship-pioneering-inc-cambridge-3xfgq1hw148d) — Cambridge, MA - [Senior Director, Business Development](https://feeny.ai/job/senior-director-business-development-flagship-pioneering-inc-cambridge-7byprykxmhya) — Cambridge, MA - [Pioneering Medicines: Medical Director / Senior Medical Director, Clinical Development Lead](https://feeny.ai/job/pioneering-medicines-medical-director-senior-medical-director-clinical-hc21y95wvzd3) — Cambridge, MA - [Senior Scientist, Protein Engineering](https://feeny.ai/job/senior-scientist-protein-engineering-flagship-pioneering-inc-cambridge-emxcvtea75rw) — Cambridge, MA - [Lead Data Engineer](https://feeny.ai/job/lead-data-engineer-flagship-pioneering-inc-cambridge-3xtagbhybhfk) — Cambridge, MA - [Senior Scientist, Immunology](https://feeny.ai/job/senior-scientist-immunology-flagship-pioneering-inc-cambridge-zb0mwy0fw9dx) — Cambridge, MA - [Director, Clinical Operations](https://feeny.ai/job/director-clinical-operations-flagship-pioneering-inc-cambridge-yqwgt65334cb) — Cambridge, MA - [Experimental Systems Intern](https://feeny.ai/job/experimental-systems-intern-flagship-pioneering-inc-cambridge-1j3zet7f9csc) — Cambridge, MA - [Director, Legal Compliance](https://feeny.ai/job/director-legal-compliance-flagship-pioneering-inc-cambridge-160ma89s9wck) — Cambridge, MA