--- title: 'Bioanalytical Lead, London at Isomorphic Labs' canonical: 'https://feeny.ai/job/bioanalytical-lead-london-isomorphic-labs-london-9ryq2wyrask7' type: 'job' last_seen: '2026-09-08' --- # Bioanalytical Lead, London at Isomorphic Labs - **Company:** Isomorphic Labs - **Location:** London, United Kingdom - **Posted:** 2026-07-09 - **Last confirmed live:** 2026-09-08 - **Apply:** https://job-boards.greenhouse.io/isomorphiclabs/jobs/6112334004 ## Job description Isomorphic Labs is applying frontier AI to help unlock deeper scientific insights, faster breakthroughs, and life-changing medicines with an ambition to solve all disease. The future is coming. A future enabled and enriched by the incredible power of machine learning. A future in which diseases are curtailed or cured starting with better and faster drug discovery. Come and be part of an interdisciplinary team driving groundbreaking innovation and play a meaningful role in contributing towards us achieving our ambitious goals, while being a part of an inspiring and collaborative culture. The world we want tomorrow is the one we’re building today. It starts with the culture at this company. It starts with you. ## About Iso Isomorphic Labs (IsoLabs) was launched in 2021 to advance human health by building on and beyond the Nobel-winning AlphaFold system. Since then, our interdisciplinary team of drug discovery experts and machine learning specialists has built powerful new predictive and generative AI models that accelerate scientific discovery at digital speed. Our name comes from the belief that there is an underlying symmetry between biology and information science. By harnessing AI’s powerful capabilities, we can use it to model complex biological phenomena to help design novel molecules, anticipate how drugs will perform and develop innovative medicines to treat and cure some of the world’s most devastating diseases. We have built a world-leading drug design engine comprising AI models that are capable of working across multiple therapeutic areas and drug modalities. We are continually innovating on model architecture and developing cutting-edge capabilities to advance rational drug design. Every day, and with each new breakthrough, we’re getting closer to the promise of digital biology, and achieving our ambitious mission to one day solve all disease with the help of AI. ## Your mission We are seeking a highly innovative and experienced Bioanalytical Lead to bridge the gap between our predictive AI design platform and wet-lab preclinical execution. In this role, you will define the overarching bioanalytical strategy across our expanding portfolio, covering small molecules, advanced biologic formats, and Antibody-Drug Conjugates (ADCs) in both non-GLP and GLP environments. You will collaborate closely with the drug design teams, design robust bioanalytical assays, manage global Contract Research Organizations (CROs), and lead the logistical execution required to rapidly advance our candidates toward IND submission. As the Bioanalytical Lead, you will serve as the technical expert for our diverse portfolio of computationally designed therapeutic candidates. As part of the preclinical development function, this is a high-impact leadership role responsible for building the bridge between Isomorphic’s AI-driven discovery engine and the effective execution of our robust preclinical strategies, alongside safety and DMPK. The successful candidate will be forward thinking, thrive in fast-paced, agile environment and ready to embrace Iso’s AI-first mindset and challenge the status quo. With a broad range of internal and external stakeholders, candidates will be expected to have exceptional communication and influencing skills. Bioanalytical Strategy & AI Integration - Define and execute comprehensive bioanalytical strategies for small molecules, large molecules, and complex modalities (ADCs) from discovery through preclinical development covering both non-GLP and GLP environments. - Oversee the design, validation, and transfer of robust PK, PD, and immunogenicity (ADA) assays at external labs. - Collaborate with AI/machine learning scientists to integrate bioanalytical data back into predictive models, helping to continuously improve our platform's accuracy. - Lead biomarker assay strategies, utilizing both traditional approaches and AI-identified novel biomarkers to support preclinical proof-of-concept. Global CRO Management & Logistics - Select, qualify, and manage a high-performing network of global CRO partners, ensuring rigorous data quality, strict timelines, and budget alignment. - Master complex global logistics, including international sample shipments, cold-chain management, import/export compliance, and stability tracking across borders to ensure data integrity. - Serve as the primary technical point of contact for CROs, troubleshooting complex assay anomalies rapidly. Cross-Functional Leadership and Regulatory Authoring - Work seamlessly at the intersection of Drug Discovery, Translational Medicine, and Computational Biology to drive candidates into the clinic. - Author and review high-quality regulatory documents, specifically bioanalytical sections of Investigational New Drug (IND) applications and Investigator Brochures (IBs). - Represent the bioanalytical function in cross-functional project teams and during interactions with regulatory agencies (FDA, EMA, etc.). Required expertise and experience - Ph.D. in Biochemistry, Analytical Chemistry, Pharmacology, or a related scientific discipline with 5+ years of biotech/pharmaceutical industry experience; OR a B.S./M.S. with 8+ years of equivalent experience. - Proven track record of leading bioanalytical strategies across multiple modalities (must include small molecules, biologics, and ADCs). - Deep understanding of GLP and non-GLP preclinical study regulations, FDA/EMA bioanalytical method validation guidelines, and ICH guidelines. - Technical & Logistical Expertise - Extensive experience with diverse analytical platforms (e.g., LC-MS/MS, LBA, flow cytometry). - Demonstrated success in biomarker assay development and validation. - Expert knowledge of global sample shipping logistics, biosafety regulations, and maintaining chain-of-custody for precious preclinical samples. - Experience writing bioanalytical sections for successful IND submissions. ## Nice to have - Experience of generating reagent in collaboration with drug design teams - Experience of developing or using AI tools (LLM) to accelerate processes including reporting Culture and values We are guided by our shared values. It's not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it. Thoughtful Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day. Brave Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less. Determined Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we. Together Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere. Creating an extraordinary company We believe that to be successful we need a team with a range of skills and talents. We're building an environment where collaboration is fundamental, learning is shared and every employee feels supported and able to thrive. We value unique experiences, knowledge, backgrounds, and perspectives, and harness these qualities to create extraordinary impact. We are committed to equal employment opportunities regardless of sex, race, religion or belief, ethnic or national origin, disability, age, citizenship, marital, domestic or civil partnership status, sexual orientation, gender identity, pregnancy or related condition (including breastfeeding) or any other basis protected by applicable law. If you have a disability or additional need that requires accommodation, please do not hesitate to let us know. Hybrid working It’s hugely important for us to share knowledge and build strong relationships with each other, and we find it easier to do this if we spend time together in person. This is why we follow a hybrid model, and would require you to be able to come into the office 3 days a week (currently Tuesday, Wednesday, and one other day depending on which team you’re in). If you have additional needs that would prevent you from following this hybrid approach, we’d be happy to talk through these if you’re selected for an initial screening call. Please note that when you submit an application, your data will be processed in line with our [privacy policy](https://www.isomorphiclabs.com/applicant-and-candidate-privacy-policy). >> [Click to view other open roles at Isomorphic Labs](https://www.isomorphiclabs.com/work-with-us#current-job-openings) ## About Isomorphic Labs ## Company Overview - **One-liner**: Isomorphic Labs is an AI-driven drug discovery company building on AlphaFold to accelerate the design of novel therapeutics and solve disease at digital speed. - **Entity Type**: Private (Series B) - **Headquarters**: London, United Kingdom (with an office in Lausanne, Switzerland) - **Founded**: 2021 - **Founders**: Sir Demis Hassabis, PhD (CEO) ## Core Business - Primary industry/industries: Biotechnology, AI-powered Drug Discovery, Healthcare - Target customers: B2B (pharmaceutical and biotech partners such as Johnson & Johnson) - Mission or purpose statement: "To one day solve all disease with the help of AI." ## Products & Services - **Isomorphic Labs Drug Design Engine**: A suite of predictive and generative AI models that go beyond AlphaFold to model complex biological phenomena, design novel molecules, anticipate drug performance, and accelerate scientific discovery at digital speed. - **Research Collaborations**: Strategic partnerships with major pharmaceutical companies (e.g., Johnson & Johnson) to co-develop drug candidates across multiple therapeutic areas. ## Market Standing - **Valuation/Market Cap**: Not publicly disclosed (recent Series B completed in February 2025) - **Key Metric**: Total Funding — Series B investment round announced February 2025 (amount not disclosed); prior funding from Alphabet as a subsidiary - **Notable Investors/Partners**: Alphabet (parent company, including Google DeepMind and Google Cloud); Johnson & Johnson (research collaboration) - **Growth Signals**: Expansion into Lausanne, Switzerland (new office); continued hiring across AI, science, and engineering roles; building on Nobel-winning AlphaFold technology; partnerships with top-tier pharma ## Competitive Advantages - **Frontier AI Access**: Sits within the Alphabet ecosystem alongside Google DeepMind, providing unique access to cutting-edge AI research and AGI development. - **AlphaFold Foundation**: Built directly on the Nobel Prize-winning AlphaFold system, giving the company a massive head start in computational biology. - **Interdisciplinary Team**: Combines world-class drug discovery experts with machine learning specialists in a high-velocity, high-trust culture. - **Ethical Framework**: Deeply integrates responsible AI development and ethical considerations into drug discovery. ## Strategic Focus - Current priorities: Scaling the Drug Design Engine, expanding partnerships with pharma, building out the Lausanne office, and advancing multiple drug discovery programs toward clinical candidates. - Long-term direction: Realizing the promise of "digital biology" to transform how medicines are discovered and developed, with the ultimate goal of solving all disease. ## Why Work Here - **Culture**: Described as "high-velocity, high-trust" — defined by urgency, curiosity, and collaboration. Core values: Brave, Determined, Together, Thoughtful. - **Remote/Hybrid**: Hybrid working model is supported; specific policies discussed during recruitment. - **Perks**: Generous employee benefits, development opportunities, access to frontier AGI research, and a mission-driven environment focused on world-changing impact. - **Engineering Culture**: Interdisciplinary teams working at the intersection of AI, biology, and medicine; emphasis on continuous learning and innovation. - **Team**: Led by a Nobel laureate (Demis Hassabis) and staffed by leaders from DeepMind, academia, and pharma. ## Sources 1. [isomorphiclabs.com](https://www.isomorphiclabs.com/) 2. [isomorphiclabs.com/careers](https://www.isomorphiclabs.com/careers) 3. [isomorphiclabs.com/life-at-iso](https://www.isomorphiclabs.com/life-at-iso) 4. [isomorphiclabs.com/work-with-us](https://www.isomorphiclabs.com/work-with-us) 5. [isomorphiclabs.com/our-team](https://www.isomorphiclabs.com/our-team) ## Other roles at Isomorphic Labs - [Research Engineer (LLM Performance), London](https://feeny.ai/job/research-engineer-llm-performance-london-isomorphic-labs-london-28vn5v8wjp0g) — London, United Kingdom - [Team Coordinator, President Team, London](https://feeny.ai/job/team-coordinator-president-team-london-isomorphic-labs-london-9sntj7e5pjdp) — London, United Kingdom - [Research Leader (DMPK), Cambridge, MA](https://feeny.ai/job/research-leader-dmpk-cambridge-ma-isomorphic-labs-cambridge-pfx6zhwy5fj1) — Cambridge, MA - [Talent Partner (Data), London](https://feeny.ai/job/talent-partner-data-london-isomorphic-labs-london-zyewt22y3rpz) — London, United Kingdom - [Research Leader / Senior Scientist (Computational Drug Design), Cambridge, MA](https://feeny.ai/job/research-leader-senior-scientist-computational-drug-design-cambridge-ma-bb4k9g76qsc9) — Cambridge, MA - [Senior Clinical Trial Manager, Cambridge, MA](https://feeny.ai/job/senior-clinical-trial-manager-cambridge-ma-isomorphic-labs-cambridge-367f9rxca8wq) — Cambridge, MA - [Program Manager, People Team, London](https://feeny.ai/job/program-manager-people-team-london-isomorphic-labs-london-tkcwz4p4ggnp) — London, United Kingdom - [Clinical Contracts Manager, Cambridge, MA](https://feeny.ai/job/clinical-contracts-manager-cambridge-ma-isomorphic-labs-cambridge-ctd4bzcwfhn1) — Cambridge, MA - [Director, Translational Medicine, Oncology, Cambridge, MA](https://feeny.ai/job/director-translational-medicine-oncology-cambridge-ma-isomorphic-labs-cambridge-bppat880d43c) — Cambridge, MA - [Director of Nonclinical Safety, Cambridge, MA](https://feeny.ai/job/director-of-nonclinical-safety-cambridge-ma-isomorphic-labs-cambridge-x2j3qdpbc08w) — Cambridge, MA