--- title: 'Clinical Trial Assistant at Lyell Immunopharma' canonical: 'https://feeny.ai/job/clinical-trial-assistant-lyell-immunopharma-seattle-washington-ckqmfv5rgrs3' type: 'job' last_seen: '2026-09-06' --- # Clinical Trial Assistant at Lyell Immunopharma - **Company:** Lyell Immunopharma - **Location:** Seattle Washington, United States - **Posted:** 2026-09-04 - **Last confirmed live:** 2026-09-06 - **Apply:** https://job-boards.greenhouse.io/lyellimmunopharma/jobs/7986540003 ## Job description Using living cells to treat – and sometimes even cure – cancer is one of the most dramatic advances in modern medicine. Patients with hematologic malignancies have been successfully treated with cell therapies. However, these profound results have not yet been achieved in patients with solid tumors, representing approximately 90% of all cancers. At Lyell, our goal is to change that. We are a clinical-stage T-cell reprogramming company advancing a diverse pipeline of cell therapies for solid tumors based on our innovative technologies. We were founded by cell therapy pioneers whose decades of research elevated the broader understanding of T-cell biology and its interaction with cancer. In our quest to defeat solid tumors, we have built a fully integrated company capable of discovering new technologies, translating science into therapies, manufacturing cell therapy products, and clinically evaluating them in patients. Our culture is based on Science, Respect, Collaboration, and Courage and reflects who we are, the environment we create, and our mission's urgency. The incumbent will support the execution of assigned clinical study tasks. ## KEY ROLE AND RESPONSIBILITIES: - Conducts trial support activities as assigned, escalates issues and recommends solutions to address concerns. - Supports drafting of study plans, process documents and creates forms as needed for efficient trial execution; collaborates and seeks feedback from broader study team stakeholders to improve/optimize recommendations - Collects and collates data from CRO/vendors, as assigned by Manager, Clinical Trials or Associate, Clinical Trials Management, reports data to stakeholders as needed, raises any issues to study lead quickly for timely resolution - Tracks inputs and deliverables day-to-day in partnership with the Clinical Operations team; identifies ways to improve the way we track study progress, reaches out to cross-functional partners for follow up and pull through. - Becomes subject matter expert in trial master file (TMF) requirements and conducts TMF review, reporting findings. Works with CRO and other vendors to support TMF maintenance by providing study documents when TMF resides with vendor. - Learns and applies ICH GCP guidelines; stays current with evolving expectations and applies new protocols as required - Tracks study expenses, as directed, tracks vendor or site invoices, routes invoices for ## PREFERRED EDUCATION: - BSc with a minimum of 7 years' experience - MSc with a minimum of 4 years' experience ## PREFERRED EXPERIENCE: - Entry-level support experience of clinical studies with some Life Sciences industry experience - Demonstrated experience with field/site monitoring, and/or sponsor in-house, and/or Oncology drug development - Proven experience supporting clinical studies for early phase and start-ups successfully treated with cell therapies. However, these profound results have not yet been achieved in patients with solid tumors, representing approximately 90% of all cancers. At Lyell, our goal is to change that. We are a clinical-stage T-cell reprogramming company advancing a diverse pipeline of cell therapies for solid tumors based on our innovative technologies. We were founded by cell therapy pioneers whose decades of research elevated the broader understanding of T-cell biology and its interaction with cancer. In our quest to defeat solid tumors, we have built a fully integrated company capable of discovering new technologies, translating science into therapies, manufacturing cell therapy products, and clinically evaluating them in patients. Our culture is based on Science, Respect, Collaboration, and Courage and reflects who we are, the environment we create, and our mission's urgency. The incumbent will support the execution of assigned clinical study tasks. ## KEY ROLE AND RESPONSIBILITIES: - Conducts trial support activities as assigned, escalates issues and recommends solutions to address concerns. - Supports drafting of study plans, process documents and creates forms as needed for efficient trial execution; collaborates and seeks feedback from broader study team stakeholders to improve/optimize recommendations - Collects and collates data from CRO/vendors, as assigned by Manager, Clinical Trials or Associate, Clinical Trials Management, reports data to stakeholders as needed, raises any issues to study lead quickly for timely resolution - Tracks inputs and deliverables day-to-day in partnership with the Clinical Operations team; identifies ways to improve the way we track study progress, reaches out to cross-functional partners for follow up and pull through. - Becomes subject matter expert in trial master file (TMF) requirements and conducts TMF review, reporting findings. Works with CRO and other vendors to support TMF maintenance by providing study documents when TMF resides with vendor. - Learns and applies ICH GCP guidelines; stays current with evolving expectations and applies new protocols as required - Tracks study expenses, as directed, tracks vendor or site invoices, routes invoices for ## PREFERRED EDUCATION: - BSc with a minimum of 7 years' experience - MSc with a minimum of 4 years' experience ## PREFERRED EXPERIENCE: - Entry-level support experience of clinical studies with some Life Sciences industry experience - Demonstrated experience with field/site monitoring, and/or sponsor in-house, and/or Oncology drug development - Proven experience supporting clinical studies for early phase and start-ups ## KNOWLEDGE, SKILLS AND ABILITIES: - Ability to continually develop an understanding of cross functional study delivery, CRO and other external vendor scope to deliver successful trial outcomes - Ability to operate effectively in cross-functional, multi-disciplinary teams - Demonstrated understanding of FDA regulations and ICH GCP guideline with an ability to successfully apply these to studies to drive effective, efficient and timely strategies The salary range for this position is $43.27 to $50.00 hourly, with the opportunity to earn an annual bonus. The salary range is an estimate, and the actual salary may vary based on Lyell’s compensation practices and an applicant’s qualifications and experience. Employees are also eligible to participate in Lyell’s Equity Incentive Plan. At Lyell, we believe that highest performing teams include people from a wide variety of backgrounds and experiences who respectfully challenge each other. We are committed to building an open, diverse and inclusive culture for all employees. Lyell is proud to be an equal opportunity employer and does not discriminate on the basis of race, color, citizenship status, national origin, ancestry, sex, sexual orientation, age, religion, creed, physical or mental disability, medical condition, marital status, veteran status or any other characteristics protected under applicable federal, state and local laws. We’ve learned from experience that some of the best people don’t always match our requirements perfectly - if you’re interested and think you could fit, please don’t hesitate to apply. ## About Lyell Immunopharma ## Company Overview - **One-liner**: Lyell Immunopharma is a clinical-stage biotechnology company advancing next-generation CAR T-cell therapies designed to deliver durable remissions for patients with cancer. - **Entity Type**: Public (ticker not explicitly confirmed in provided sources; investor relations page indicates public reporting) - **Headquarters**: South San Francisco, California, United States - **Founded**: Not publicly available from provided sources - **Founders**: Rick Klausner, M.D. (Founder & Chairman), Crystal Mackall, M.D. (Founder), Stan Riddell, M.D. (Founder) ## Core Business - **Primary industry**: Biotechnology – Cell Therapy / Oncology - **Target customers**: B2B (healthcare providers, clinical trial sites, and patients seeking one-time cell therapies) - **Mission / purpose**: “To fully realize the curative potential of cell therapy for patients with cancer” – advancing next-generation CAR T cells that provide potent, long-lasting responses in both hematologic malignancies and solid tumors. ## Products & Services - **Ronde-Cel (LYL797)**: A next-generation CAR T-cell product candidate targeting ROR1 in solid tumors; currently presenting clinical and translational data at conferences like ASH 2025. - **Other pipeline candidates**: Multiple undisclosed product candidates for hematologic malignancies and solid tumors, designed with novel CAR constructs, T-cell exhaustion‑resistance technologies, and proprietary manufacturing protocols. ## Market Standing - **Valuation / Market Cap**: Not publicly available from provided sources - **Key Metric**: Clinical-stage; no approved product yet. Most recent disclosed financing is a $50 million tranche of equity private placement (closed April 2026). - **Notable Investors / Partners**: Not explicitly listed in provided data; investors likely include those from private placements and institutional holders (details not available). - **Growth Signals**: - Clinical progress with Ronde-Cel in solid tumors - State-of-the-art manufacturing facility in Bothell, WA, approved for clinical and commercial production - Active pipeline across hematologic and solid tumor indications - Establishment of three West Coast hubs (South San Francisco HQ, Seattle, Bothell) ## Competitive Advantages - **Proprietary T-cell biology**: Pioneering approaches to prevent T-cell exhaustion, enabling longer‑lived and more potent cancer killing. - **End‑to‑end control**: Own and operate a dedicated manufacturing facility, ensuring supply chain control and product quality. - **Founding by cell‑therapy pioneers**: Founders (Klausner, Mackall, Riddell) are leaders in the field, providing deep scientific expertise. ## Strategic Focus - **Pipeline advancement**: Progress next‑generation CAR T candidates through clinical trials, aiming to improve outcomes over first‑generation CAR T therapies. - **Solid tumor expansion**: Aggressively develop therapies for solid tumors where current cell therapies have limited efficacy. - **Manufacturing scale‑up**: Leverage internal manufacturing to accelerate development and eventual commercialization. ## Why Work Here - **Culture**: Described as “grounded in science, infused with courage, and powered by respect and collaboration.” Employees report feeling welcomed and able to contribute, with diverse perspectives valued. - **Work model**: Hybrid – in‑office collaboration days and weekly lunches; offices in South San Francisco, Seattle (South Lake Union), and Bothell. - **Benefits**: - Comprehensive medical, dental, vision (up to 100% premium for employees, 85% for dependents) - Employee Stock Purchase Plan (ESPP) with 15% discount - 401(k) matching - FSA/HSA options - Company‑sponsored life insurance, short‑ and long‑term disability - Paid vacation and sick time - Commuter benefit - Wellness program (mental health, physical fitness, financial wellness) ## Sources 1. [Lyell.com – Company Overview](https://www.lyell.com/) 2. [Lyell.com – Careers](https://www.lyell.com/careers/) 3. [Lyell.com – Job Openings](https://www.lyell.com/careers/job-openings/) 4. [Lyell.com – Investor Relations](https://ir.lyell.com/investor-relations) 5. [Lyell.com – Leadership](https://www.lyell.com/about/leadership/) ## Other roles at Lyell Immunopharma - [Director, Medical Writing](https://feeny.ai/job/director-medical-writing-lyell-immunopharma-united-states-vhfy2mbbyfy2) — United States - [Associate Director, FP&A](https://feeny.ai/job/associate-director-fp-a-lyell-immunopharma-south-san-francisco-california-xv34y6x78vjv) — South San Francisco California, United States - [Associate Director, Clinical Development Program Management](https://feeny.ai/job/associate-director-clinical-development-program-management-lyell-immunopharma-p0yy7kq7ngdh) — South San Francisco California, United States - [Senior Manager, Clinical Site Budgets and Outsourcing - contract position](https://feeny.ai/job/senior-manager-clinical-site-budgets-and-outsourcing-contract-position-lyell-se4hdrf04a9b) — United States - [Director or Senior Director, Investor Relations and Corporate Communications](https://feeny.ai/job/director-or-senior-director-investor-relations-and-corporate-communications-e9h5mes0s5ce) — United States - [Director, Regulatory Affairs](https://feeny.ai/job/director-regulatory-affairs-lyell-immunopharma-seattle-washington-79r3gcjrr7eh) — Seattle Washington, United States / South San Francisco California, United States - [Associate Director, CMC Regulatory](https://feeny.ai/job/associate-director-cmc-regulatory-lyell-immunopharma-seattle-washington-ase0cen8tsjf) — Seattle Washington, United States - [Director, Clinical Science](https://feeny.ai/job/director-clinical-science-lyell-immunopharma-united-states-8qzzt8p94g0x) — United States - [Director, Medical Affairs Operations](https://feeny.ai/job/director-medical-affairs-operations-lyell-immunopharma-united-states-2yw8q0bfn11t) — United States - [Principal, Quality Assurance](https://feeny.ai/job/principal-quality-assurance-lyell-immunopharma-bothell-washington-2n68z54b0gcx) — Bothell Washington, United States