--- title: 'Computational Biologist at Freenome' canonical: 'https://feeny.ai/job/computational-biologist-freenome-remote-cgja26st5bqf' type: 'job' last_seen: '2026-11-09' --- # Computational Biologist at Freenome - **Company:** Freenome - **Location:** Remote - **Work type:** remote - **Posted:** 2026-11-05 - **Last confirmed live:** 2026-11-09 - **Apply:** https://job-boards.greenhouse.io/freenome/jobs/8920182002 ## Job description About this opportunity: At Freenome, we are seeking a Computational Biologist, Assay Development to help grow the Freenome’s Computational Biology, Assay Development (CBAD) team (can be a Senior Computational Biologist role depending on experience). As part of our team, you will  apply your scientific expertise to the development of early, noninvasive tests for cancer detection. With a strong background in bioinformatics, statistics, and molecular biology, you will develop, write, and execute analysis plans and reports for the development and characterization of Freenome’s in vitro diagnostic devices and regulatory filings. You will work closely and cross-functionally with many teams, including Regulatory and Quality, Molecular Research and Development, Laboratory Operations, Biostatistics, Computational Science, and Engineering to enable the successful development of multiple molecular assays as part of Freenome’s diagnostic products. The role reports to the Director of Computational Biology. This position can be a hybrid or fully remote role. What you’ll do: - Plan and execute development experiments for Freenome’s multiomics cancer screening tests. - Partner cross-functionally with computational, development, regulatory, and quality leaders to develop and execute a regulated development strategy working toward FDA approval. - Use your quantitative skills to develop computational methods and interpret complex experimental results in order to optimize and validate innovative technology for sample collection, preparation, and detection. - Develop and execute appropriate experimental design and analysis plans for Development, Verification, and Validation studies, closely partnering with Biostatistics, Development, and Pre-Analytics teams. - Work closely with molecular and computational research teams developing Freenome’s IVD products for blood-based molecular assays including cell-free DNA, proteins, and additional biomarkers. - Impact patient lives through the development and launch of high quality cancer screening technologies Must haves: - Post-graduate degree (MS or PhD) in statistics, computational biology, bioinformatics, cancer biology, or related quantitative field. - 2-3+ years of industry experience (for Sr. Scientist level) - Experience in experimental design and analysis of high-throughput, quantitative technologies in genomics, epigenomics, transcriptomics, or proteomics (e.g. target capture with UMI, Hi-C, ATAC-seq, RNA-seq, bisulfite sequencing, microarrays, mass spec, immunoassays). - Familiarity with and ability to select and leverage bioinformatics tools for the above molecular assays. - Experience in applied statistics, such as in hypothesis testing, regression techniques, and appropriate use of simulation. - Expertise in data analysis and visualization using R (tidyverse), or Python statistical packages (Numpy, Matplotlib, Pandas), or equivalent, under version control. - Excellent oral and written communication skills to communicate to scientific and broader audiences, with keen attention to detail. - Ability to work on a cross-functional team in our highly collaborative environment, working with both computational and experimental scientists. Nice to haves: - Experience in the development of diagnostic devices in a regulated environment (PMA, 510(k), CE-IVD) preferred (for Sr. Scientist level). Benefits and additional information: The US target range of our base salary for new hires is $131,325 - $189,525. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered.  Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ [freenome.com/job-openings/](http://freenome.com/job-openings/) for additional company information. Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law. Applicants have rights under Federal Employment Laws. - https://www.dol.gov/agencies/whd/posters/fmla - https://www.dol.gov/agencies/ofccp/posters - https://www.dol.gov/agencies/whd/posters/employee-polygraph-protection-act California applicants please review the CCPA Notice at Collection here: - https://www.freenome.com/ccpa-privacy-notice-for-freenome-california-job-applicants/ #LI-Remote ## About Freenome ## Company Overview - **One-liner**: Freenome is a biotechnology company developing blood-based multi-omics tests powered by machine learning to detect cancer in its earliest, most treatable stages. - **Entity Type**: Private (Late Stage) – raised over $2B in total funding; stock symbol FRNM (NASDAQ) is associated with a related SPAC entity but the operating company remains privately held [linkedin.com] - **Headquarters**: Brisbane, California, United States - **Founded**: 2014 - **Founders**: Riley Ennis (Co-Founder and Chief Product Officer) and others [freenome.com] ## Core Business - **Primary industry**: Biotechnology / Early Cancer Detection - **Target customers**: B2B (health systems, insurers, employers) and B2C (patients via healthcare providers) - **Mission**: To create tools that empower everyone to prevent, detect, and treat their disease, starting with early cancer detection. ## Products & Services - **Freenome Multi-Omics Blood Test (Colorectal Cancer)**: A next-generation blood test that uses a multi-omics platform (cell-free DNA, methylation, proteins, etc.) combined with machine learning to detect early-stage colorectal cancer and advanced adenomas. Type: Diagnostic test (IVD) – currently under clinical validation and regulatory review [freenome.com]. ## Market Standing - **Valuation / Market Cap**: Not publicly disclosed (private). Total funding of $2.07B (LinkedIn estimate) or $1.428B (CB Insights); conflicting reports reflect different counting methods [linkedin.com], [cbinsights.com] - **Key Metric (Funding)**: Most recent round – $75M corporate round (Nov 2025) led by Roche, plus $254M venture round (Feb 2024) also led by Roche [linkedin.com] - **Notable Investors**: Perceptive Advisors, RA Capital Management, Roche Venture Fund, Kaiser Permanente, Novartis, American Cancer Society’s BrightEdge Ventures, Exact Sciences [linkedin.com], [freenome.com] - **Growth Signals**: - Blood-based test included in updated American Cancer Society colorectal cancer screening guideline - Appointed industry veteran Rob Guigley as Chief Commercial Officer (2025) - Ongoing clinical programs for multiple cancer types - Employee headcount of 304 with 22 active job postings (as of mid-2025) [linkedin.com] ## Competitive Advantages - **Multi-omics + AI platform**: Combines multiple biological signals (DNA methylation, fragmentomics, proteins) with proprietary machine learning algorithms to achieve high sensitivity and specificity for early-stage cancer. - **Strong clinical program**: Rigorous multi-site studies and partnerships with leading health systems (e.g., Kaiser Permanente). - **Deep investor backing**: Long-term support from top healthcare investors and strategic partners (Roche, Exact Sciences) provides capital and commercial pathways. - **First-mover in multi-cancer blood screening**: Focus on colorectal cancer as first indication, with potential to expand to other cancers. ## Strategic Focus - **Clinical validation & regulatory approval**: Completing pivotal studies and preparing FDA submission for colorectal cancer test. - **Commercial launch preparation**: Building commercial team (hiring Strategic Account Executives, VP Revenue Cycle Management) and establishing relationships with payers and health systems. - **Platform expansion**: Extending multi-omics technology to additional cancer types (lung, pancreatic, etc.) through research programs. ## Why Work Here - **Mission-driven culture**: Employees are motivated by the opportunity to “outpace cancer” and make a tangible impact on patient lives. Values include integrity, empathy, trust, servant leadership, and striving for greatness [freenome.com]. - **Equity ownership**: Every U.S. full-time employee receives equity packages, aligning personal success with company milestones [freenome.com/careers]. - **Competitive benefits**: Comprehensive medical plans, wellness programs, generous PTO, 12 paid holidays, annual bonus opportunities, and market-based salaries [freenome.com/careers]. - **Collaborative environment**: Cross-functional teams across clinical, scientific, and business domains; emphasis on respect and inclusion [freenome.com/careers]. - **Work model**: Likely office-based in Brisbane, CA (hybrid flexibility not explicitly stated). The company has a physical lab and office presence. - **Engineering & science culture**: Opportunity to work with state-of-the-art multi-omics data, machine learning, and clinical trial design. The team includes senior ML scientists, computational biologists, and software engineers. ## Sources 1. [freenome.com](https://www.freenome.com/) – Company overview, leadership, values, products 2. [freenome.com/careers](https://www.freenome.com/careers/) – Benefits, culture, job openings 3. [linkedin.com/company/freenome](https://www.linkedin.com/company/freenome) – Employee count, revenue estimate, funding rounds, investor list, recent hires and departures 4. [cbinsights.com/company/freenome](https://www.cbinsights.com/company/freenome) – Funding total, company description, patent activity ## Other roles at Freenome - [Staff Software Engineer](https://feeny.ai/job/staff-software-engineer-freenome-remote-68wakx1nw87x) - [Senior Staff Software Engineer](https://feeny.ai/job/senior-staff-software-engineer-freenome-remote-967fagps50tx) - [Senior Manager, Total Rewards](https://feeny.ai/job/senior-manager-total-rewards-freenome-brisbane-xzsxfrbn4zna) — Brisbane, CA - [Senior Systems Integration Engineer](https://feeny.ai/job/senior-systems-integration-engineer-freenome-brisbane-685r3d1r8b6w) — Brisbane, CA - [Senior Software Engineer, Site Reliability](https://feeny.ai/job/senior-software-engineer-site-reliability-freenome-remote-wmcdmqnnq13n) - [Postmarket Quality Manager](https://feeny.ai/job/postmarket-quality-manager-freenome-brisbane-tf35b1srzbq0) — Brisbane, CA - [Staff Technical Operations Scientist](https://feeny.ai/job/staff-technical-operations-scientist-freenome-brisbane-5xdj1a8tctn9) — Brisbane, CA - [Quality Control Specialist I (Contractor)](https://feeny.ai/job/quality-control-specialist-i-contractor-freenome-brisbane-mc4bcf1nyhjs) — Brisbane, CA - [Quality Control Specialist II (Contractor)](https://feeny.ai/job/quality-control-specialist-ii-contractor-freenome-brisbane-94f4tb6dq8g8) — Brisbane, CA - [Senior Biostatistician](https://feeny.ai/job/senior-biostatistician-freenome-remote-dah4h40pkygs)