---
title: 'Controller at Ossium Health'
canonical: 'https://feeny.ai/job/controller-ossium-health-san-francisco-zkeha5vh6e4q'
type: 'job'
last_seen: '2026-11-02'
---

# Controller at Ossium Health

- **Company:** Ossium Health
- **Location:** San Francisco, CA
- **Posted:** 2026-10-20
- **Last confirmed live:** 2026-11-02
- **Apply:** https://ossiumhealth.com/jd?gh_jid=4723269006

## Job description

## About Ossium

Ossium’s mission is to improve the health, vitality, and longevity of human beings through bioengineering. We develop, manufacture, and bank cell therapy products that apply the power of stem cell science to revolutionize treatment for patients with blood, immune, and orthopedic diseases.  At Ossium, we empower our employees, maintain the highest standards of operational excellence, and are a force for good.

## About the Job

We are hiring a Director-level Controller to lead and strengthen Ossium’s accounting function as we scale. Reporting to our VP, Finance, you’ll lead a small team to start and own our accounting function so that our financial reporting keeps pace with our operations.

This role centers on raising the quality, speed, and reliability of our accounting operations. Responsibilities include leading the month-end close and preparing monthly flux analyses. You'll drive the annual financial statement audit under AICPA standards, managing the auditor relationship and working closely with our technical accounting team on complex areas such as revenue recognition, stock-based compensation, and new transactions. The role also involves strengthening our internal control environment, refining policies and procedures, and supporting accounting for R&D and clinical expense accruals, government grant/contract funding, and equity. Finally, you'll partner with the VP, Finance on budgeting and forecasting and prepare clear written analyses and memos for auditors, leadership, and investors.

Our ideal candidate is a hands-on leader who enjoys both rolling up their sleeves and setting direction. You’re detail-obsessed, energized by improving processes and systems, comfortable coaching a small team, and confident communicating with internal partners and external stakeholders alike.

Required Qualifications

- 10+ years of progressive accounting experience, including 3+ years in public accounting and 3+ years in a Controller/Assistant Controller role
- 3+ years of direct people management; hiring, coaching, and developing staff
- Proven track record of owning the full month-end, quarter-end, and year-end close process, including preparing financial statements and flux/variance analyses
- Experience leading financial statement audits end to end; preparing audit schedules, managing PBC requests, and serving as the primary point of contact
- Strong technical knowledge of US GAAP; the ability to research accounting issues and prepare technical memos
- Experience with inventory and cost accounting
- Hands-on experience with Netsuite and Bill.com
- Proven ability to work cross-functionally with internal teams
- Advanced Excel and analytical skills
- Excellent verbal and written communication, including the ability to explain financial results clearly to non-finance stakeholders
- This position is based in our San Francisco office; we maintain a hybrid schedule of Monday through Thursday in the office, with Friday as a remote work day

## Preferred Qualifications

- Experience in a biotech, pharmaceutical, or FDA-regulated life sciences company
- Experience with cost accounting in a manufacturing, GMP, or lab-processing environment, including standard costing and inventory valuation for biological or perishable products
- Implementation of an inventory module/integration of an inventory management system with NetSuite
- Experience with clinical trial/R&D expense accruals, including CRO & CDMO arrangements
- Experience accounting for government grants or contracts

## Key Responsibilities

- Lead, mentor, and develop the accounting team; set priorities/review work; help plan future growth
- Oversee all corporate accounting functions, including AP/AR, revenue, payroll accounting, fixed assets, and financial reporting
- Own the monthly, quarterly, and year-end close; prepare financial statements in accordance with US GAAP within management’s timelines
- Prepare monthly flux analyses and report on variances and trends to the VP, Finance and leadership
- Lead the annual financial statement audit, manage the auditor relationship, and coordinate with our technical accounting team on complex accounting matters
- Partner with Supply Chain and Ops to bring inventory accounting fully into NetSuite
- Design, document, and maintain internal controls to reduce financial risk and ensure the accuracy of company records
- Identify/implement improvements to accounting processes, policies, & procedures
- Work with leaders across Ossium to optimize our accounting and finance systems and scale processes that support business growth
- Manage external relationships for audit, banking, compliance, insurance, and tax
- Prepare polished written documents, such as technical memos, auditor responses, and answers to investor questions

In your first six months some projects you’ll work on include:

- Completing our 2025 financial statement audit
- Planning, kicking off, and completing our 2026 financial statement audit
- Kicking off the project to bring inventory accounting fully into NetSuite
- Getting to know the month-end close and identifying early opportunities to tighten the timeline, improve flux reporting, and strengthen controls

This position has a salary range of $195,000 - $240,000 annually. Ossium Health takes a market-based approach to pay. The successful candidate’s starting salary will be determined based on, but not limited to, job-related skills, experience, qualifications, and market conditions. This range may be modified in the future.

We offer a full slate of employee benefits including:

- Stock options
- 401(k) matching
- Medical, dental and vision coverage
- Four weeks of PTO accrued (vacation & sick time) annually  + 11 company holidays
- Employer paid life insurance and long term disability
- Gym membership/recreational sports reimbursements

Ossium Health provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, disability, protected veteran status, sexual orientation, gender identity, gender expression, or any other protected characteristic. Our [Equal Employment Opportunity Policy Statement](https://ossiumhealth.com/wp-content/uploads/2025/05/Ossium-Health-2024-Equal-Employment-Opportunity-Policy-Statement.pdf) and the [Know Your Rights: Workplace Discrimination is Illegal Poster](https://www.eeoc.gov/sites/default/files/2023-06/22-088_EEOC_KnowYourRights6.12.pdf) reaffirm this commitment. Pursuant to the San Francisco Fair Chance Ordinance, we will consider for employment qualified applicants with arrest and conviction records.

If reasonable accommodation is needed, please contact our People Team at careers@ossiumhealth.com or 650-285-0603. Ossium Health complies with federal and state disability laws and makes reasonable accommodations for applicants and candidates with disabilities.

Principals / direct applicants only please. Recruiters, please do not contact this job poster.

## Equal Opportunity Employer/Veterans/Disabled

## About Ossium Health

## Company Overview
- **One-liner**: Ossium Health is a clinical-stage bioengineering company that creates life-saving stem cell therapies from deceased donors for use in bone marrow transplants and other blood and immune system diseases.
- **Entity Type**: Private (Series C)
- **Headquarters**: San Francisco, California, USA (with a manufacturing facility in Indianapolis, Indiana, USA)
- **Founded**: 2016
- **Founders**: Kevin Caldwell (CEO, Co-Founder) and Erik Woods (Chief Science Officer, Co-Founder)

## Core Business
- **Industry**: Biotechnology / Cell Therapy
- **Target Customers**: B2B – healthcare providers (transplant centers), life science companies (biopharma partners), and organ procurement organizations (OPOs)
- **Mission**: “To improve human health through bioengineering” and “Establish a new source for life-saving stem cells” by bringing the deceased donor transplant ecosystem into the fight against diseases of the blood and immune systems.

## Products & Services
- **HPC, Marrow (Hematopoietic Progenitor Cells from marrow)**: An allogeneic stem cell product derived from vertebral body donors, used in bone marrow transplants. First patient successfully engrafted at Henry Ford Health in June 2024.
- **OssiGraft**: An orthopedic product (first patient treated November 2023) – marks the company’s entry into orthopedics.
- **CD34+ Product**: A purified hematopoietic stem cell product used in a multivisceral transplant study at Columbia University Medical Center (first patient November 2021).
- **Platform Model**: A proprietary process for recovering, processing, and cryopreserving cells from deceased donors, enabling off-the-shelf cell therapies.

## Market Standing
- **Valuation/Market Cap**: Not disclosed
- **Key Metric**: **Total Funding** – USD 128.9 million across multiple rounds (Seed, Series A, Series B, Series C, and a grant)
- **Notable Investors/Partners**:
  - Lead investors: CPMG (Series C lead), Vivo Capital (Series B co-lead), General Catalyst (Series B co-lead), First Round Capital (Series A lead)
  - Other investors: Manta Ray Ventures, Village Global, Asahi Kasei, Alumni Ventures
  - Federal partner: Biomedical Advanced Research and Development Authority (BARDA) – contract for radiological/nuclear emergency preparedness
- **Growth Signals**:
  - Headcount: ~75 employees, with +13.3% yearly growth (LinkedIn)
  - Active job postings: 14 (as of mid-2025)
  - Recent clinical milestones: first patient engrafted with HPC Marrow (June 2024) and first OssiGraft patient (Nov 2023)
  - Series C closed July 2023 ($52M)
  - Expanded into orthopedics and federal preparedness markets

## Competitive Advantages
- **Unique Cell Source**: Uses deceased donors (vertebral bodies) rather than living donors or iPSCs, leveraging an existing transplant network to produce scalable, off-the-shelf allogeneic cell therapies.
- **Proprietary Processing & Cryopreservation**: Founders have deep expertise in cryobiology; Dr. Woods co-invented the first closed-system cryovial for cell therapy (CellSeal®) and commercial human platelet lysate (Stemulate®).
- **Regulatory & Operational Infrastructure**: CLIA-certified lab, FDA-registered facility, and AABB accreditation; experienced in high-complexity clinical cell manufacturing.
- **Government Partnership**: BARDA contract validates the platform for national emergency preparedness, providing a stable, non-dilutive revenue stream and strategic credibility.

## Strategic Focus
- Advance clinical trials for HPC Marrow in bone marrow transplant (lead indication) and expand into orthopedics with OssiGraft.
- Strengthen partnerships with OPOs and healthcare systems to increase donor tissue access.
- Scale manufacturing capacity at the Indianapolis facility to meet commercial and federal contract demand.
- Continue to develop additional cell therapy programs (e.g., immune effector cells, mesenchymal stromal cells) using the same platform.

## Why Work Here
- **Culture & Values**: Emphasizes Truth (data-driven decision making), Ownership (high accountability), Grit (persistence toward mission), and Impact (improving human health).
- **Mission-Driven**: Employees are motivated by the chance to fight diseases like leukemia and lymphoma, and to contribute to national health security (BARDA partnership).
- **Work Environment**: Two locations – San Francisco HQ (office) and Indianapolis facility (cell manufacturing lab). Roles span clinical production, recovery services, quality assurance, research, and commercial. Likely on-site for lab and manufacturing roles.
- **Growth Opportunity**: Rapidly scaling company with recent clinical wins and a growing headcount; employees can take ownership of impactful projects early in their careers.
- **Notable Perks**: Not detailed in search results, but the company highlights “empowering employees, maintaining the highest standards of excellence, and being a force for good.”

## Sources
1. [Ossium Health – Careers Page](https://ossiumhealth.com/careers/)
2. [Ossium Health – Homepage](https://ossiumhealth.com/)
3. [Ossium Health – Company About](https://ossiumhealth.com/company/)
4. [Ossium Health – Our Team](https://ossiumhealth.com/our-team/)
5. [Ossium Health – LinkedIn Company Profile](https://www.linkedin.com/company/ossiumhealth)

## Other roles at Ossium Health

- [Operations Manager, HPC](https://feeny.ai/job/operations-manager-hpc-ossium-health-indianapolis-gha9s2wvmy47) — Indianapolis, IN
- [Production Supervisor, HPC, Marrow](https://feeny.ai/job/production-supervisor-hpc-marrow-ossium-health-indianapolis-c7s100bpyqh4) — Indianapolis, IN
- [Chief Financial Officer](https://feeny.ai/job/chief-financial-officer-ossium-health-san-francisco-cra5q8ffrrrs) — San Francisco, CA
- [Regional Manager, Orthopedics](https://feeny.ai/job/regional-manager-orthopedics-ossium-health-e3frwsynacgq)
- [Tissue Recovery Specialist (Contract) - Northern OR Southern Indiana](https://feeny.ai/job/tissue-recovery-specialist-contract-northern-or-southern-indiana-ossium-health-rmvccntaz5r9) — Field Based: Northern, IN / Field Based: Southern, IN
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