---
title: 'Director, Clinical Operations at Aspect Biosystems'
canonical: 'https://feeny.ai/job/director-clinical-operations-aspect-biosystems-vancouver-7m94smmk3132'
type: 'job'
last_seen: '2026-09-18'
---

# Director, Clinical Operations at Aspect Biosystems

- **Company:** Aspect Biosystems
- **Location:** Vancouver, Canada
- **Work type:** onsite
- **Posted:** 2026-09-16
- **Last confirmed live:** 2026-09-18
- **Apply:** https://job-boards.greenhouse.io/aspectbiosystems/jobs/5418594008

## Job description

We are seeking an innovative and self-motivated Director of Clinical Operations to help lead clinical development of our advanced cell therapy programs. Reporting to the Chief Development Officer, you will oversee and directly contribute to the execution and strategy of the company’s global clinical trials. You will be key to establishing investigator, vendor, and cross-department partnerships while building our internal Clinical capacity as our pipeline advances. You’ll be joining a company committed to developing regenerative medicines that deliver life-changing, functional cures for patients living with serious diseases. This role could be based on-site in Vancouver, Canada or Fremont, California.

## Responsibilities

- Lead the end-to-end operational strategy, startup, execution, and closeout of global Phase I-III cell therapy clinical trials, flexing to support additional responsibilities assigned by leadership.
- Translate clinical development plans into actionable operational milestones, study budgets, resource plans, and risk-mitigation strategies.
- Direct cross-functional study execution teams—including Clinical Development, Regulatory, Quality, CMC, and Data Management—while championing cross-departmental knowledge sharing.
- Partner with CMC and Supply Chain to establish specialized cell therapy protocols, including chain-of-identity (COI), chain-of-custody (COC), cryogenic transport, and site handling.
- Author, review, and standardize trial-related documents, protocols, informed consents, Investigator's Brochures, study manuals, and Clinical Operations SOPs.
- Drive international site identification, feasibility, qualification, and activation, targeting specialized academic medical centers, endocrinology units, and cell therapy treatment centers.
- Manage clinical portions of regional regulatory submissions (FDA, EMA, Health Canada, MHRA) and ethics approvals in collaboration with Regulatory Affairs and local CRO partners.
- Develop country-specific patient recruitment and retention strategies tailored to target populations.
- Identify, build, and nurture key opinion leader (KOL) and site investigator partnerships.
- Lead vendor selection (RFPs, bid defenses, negotiations) and maintain active oversight, performance governance, scope tracking, and quality management for CROs, central labs, and specialty providers.
- Create, negotiate, review, and approve clinical trial, vendor, site, and department budgets, as well as invoices, change orders, and accruals in partnership with Finance.
- Build and scale the Clinical department by establishing foundational SOPs, setting up eTMF structures, and hiring, training, and managing team members.
- Ensure all trial activities, sites, eTMF systems, and vendor records maintain inspection readiness and comply with ICH-GCP guidelines and global cell/gene therapy regulations

## Qualifications & Experience

- Education: Bachelor’s degree in Life Sciences, Nursing or related scientific discipline required. A Masters degree would be highly beneficial to your application.
- Experience: 8 years of related experience with progressively increasing responsibilities in roles involving the conduct of clinical trials with 4 of those years in a leadership position (less experienced, driven individuals will be considered).
- You have previous experience in the following areas:
- Developing cell or gene therapy products including rare diseases.
- Leading early clinical development programs including the launch of first-in-human trials.
- Experience working in early-stage, fast-paced biotechnology environments with lean internal teams.
- Surgical route of administration for investigational products.
- Knowledge: You have a solid understanding and application of ICH Guidelines, Code of Federal Regulations and GCP. You have a proven working knowledge of the complex logistics unique to cell therapies. You have a track record of operationalizing and managing multi-center, multi-national Phase I-III trials. You have strong experience issuing RFP’s, selecting CRO’s and speciality vendors, and managing complex program budgets.
- You have a deep understanding of global regulatory frameworks governing advanced therapy medicinal products (ATMP’s) / cellular therapy regenerative medicines.
- You work with a sense of urgency, are results-driven, and thrive in a fast-paced, interdisciplinary, and entrepreneurial environment. You are willing to roll up your sleeves and do what it takes to get the job done.
- You are highly adaptable, agile, and poised when faced with change, ambiguity, and competing priorities.
- You love immersing yourself in difficult technical problems and coming up with solutions that work. You think outside the box and use your experience and intuition to identify when such solutions are realistic.
- You thrive in a multi-disciplinary team environment and believe that we can get further, faster by working together.

The hiring range for this role is $185,000 - $270,000 , annually. Our pay scales are based on market data to ensure that compensation is competitive and fair. Offered salaries will be based on a combination of factors including, but not limited to, job-related knowledge, skills, education, and experience. For candidates who exceed role requirements, we are open to exploring above-range offers. Base salary is just one part of the overall compensation at Aspect, team members also receive equity, a comprehensive benefits package, and support for continuous learning and career progression.

## Who We Are

Aspect Biosystems is a biotechnology company pioneering the development of a novel category of regenerative medicine designed to restore or supplement biological function and deliver curative therapies for some of the most elusive diseases. Aspect is developing these bioengineered cellular medicines by applying its full-stack tissue therapeutic platform, which integrates proprietary AI-powered bioprinting technology, therapeutic cells, hypoimmune cell engineering, and advanced biomaterials. Aspect is advancing its therapeutic pipeline across multiple endocrine and metabolic diseases, including diabetes and rare endocrine disorders. If you are committed to making a real impact and accelerating the development of life-changing therapies, we want to hear from you!

Curious about our current perks and benefits? Learn more [here](https://aspectbiosystems.com/careers).

At Aspect Biosystems, our strength has always been in our diversity. Different people, thinking differently, unified in creating a world that is better for us all. We are committed to creating an inclusive environment for everyone on our team.

All aspects of employment — including the decision to hire, promote, discipline, or terminate — are based on merit, competence, performance, and business needs. We do not discriminate on the basis of race, color, religion, citizenship status, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, political affiliation, or any other status protected under federal, state, provincial, or local law.

If you're interested in joining our team but don't see a job posting that matches your experience or background, we encourage you to [submit a general application](https://boards.greenhouse.io/aspectbiosystems/jobs/4009049008) to be considered for future opportunities!

## About Aspect Biosystems

## Company Overview
- **One-liner**: Aspect Biosystems is a Canadian biotechnology company pioneering the development of Bioprinted Tissue Therapeutics—implantable, bioengineered cellular medicines designed to replace, repair, or supplement biological function to treat incurable diseases.
- **Entity Type**: Private (Series Unknown; raised US$350M+ in total capital)
- **Headquarters**: Vancouver, British Columbia, Canada
- **Founded**: 2013
- **Founders**: Tamer Mohamed (CEO), Simon Beyer (CTO), Sam Wadsworth (CSO)

## Core Business
- **Primary Industry**: Biotechnology / Regenerative Medicine / Tissue Engineering
- **Target Customers**: B2B (pharmaceutical and biotech partners for co-development and clinical trials), and ultimately B2B2C (patients with metabolic and endocrine diseases such as diabetes).
- **Mission**: To develop Bioprinted Tissue Therapeutics that replace, repair, or supplement biological function, transforming the treatment of incurable diseases.

## Products & Services
- **Bioprinted Tissue Therapeutics (Pipeline)**: Implantable, allogeneic tissues designed to treat metabolic and endocrine diseases (e.g., diabetes, rare endocrine disorders). These are bioengineered cellular medicines that integrate proprietary AI-powered bioprinting, therapeutic cells, hypoimmune cell engineering, and advanced biomaterials.
- **Full-Stack Tissue Therapeutic Platform**: A vertically integrated technology stack that includes AI-powered bioprinting systems, microfluidic printheads, lab automation, software, machine learning, and computational design tools. This platform is used for internal pipeline development and partnered programs.
- **Partnerships (Co-Development)**: Collaborates with pharmaceutical and biotech leaders (e.g., Novo Nordisk) to bring cutting-edge cell therapies to the clinic, leveraging its platform for co-development.

## Market Standing
- **Valuation/Market Cap**: Not publicly disclosed.
- **Key Metric**: Total funding raised is over US$350M (including a US$280M partnership with the Government of Canada announced in 2026, a US$115M round in 2024, and a US$72.75M government investment in 2024). LinkedIn reports total funding at US$278.7M.
- **Notable Investors/Partners**: Novo Nordisk (major pharma partner), Government of Canada (major strategic partner), Western Innovation (WINN) Initiative, entrepreneurship@UBC.
- **Growth Signals**: Headcount grew 26.5% YoY to 116 employees. Announced a new phase of partnership with Novo Nordisk in January 2026. Secured a US$280M partnership with the Government of Canada in April 2026. Won multiple awards including Life Sciences BC Company of the Year 2024 and BIOTECanada Biotech Company of the Year.

## Competitive Advantages
- **Full-Stack Platform**: Integrates proprietary AI-powered bioprinting, therapeutic cells, hypoimmune cell engineering, and advanced biomaterials—a vertically integrated approach that is difficult to replicate.
- **Strategic Partnerships**: Deep, multi-phase partnership with Novo Nordisk, a global leader in diabetes care, providing validation, funding, and clinical development expertise.
- **Government Support**: Significant non-dilutive funding and strategic backing from the Government of Canada (US$280M partnership), providing a strong financial runway and national-level support.
- **Experienced Leadership Team**: Leadership includes executives with deep experience from Vertex Pharmaceuticals, Novo Nordisk, BlueRock Therapeutics (Bayer), and ViaCyte (Vertex), bringing proven expertise in advancing cell therapies from research to late-stage clinical development.

## Strategic Focus
- **Clinical Translation**: Advancing its pipeline of Bioprinted Tissue Therapeutics toward first-in-human clinical trials, with a strong focus on diabetes and rare endocrine disorders.
- **Platform Expansion**: Continuing to develop and vertically integrate its full-stack tissue therapeutic platform (AI bioprinting, cell engineering, biomaterials) to enable a broad pipeline of therapies.
- **Strategic Partnerships**: Deepening its collaboration with Novo Nordisk to develop curative medicines for diabetes, and seeking additional pharma/biotech partners to leverage its platform for other indications.
- **Manufacturing & Scale-Up**: Building out technical operations, process development, and manufacturing capabilities to support clinical translation and eventual commercialization.

## Why Work Here
- **Mission-Driven Work**: Employees are directly contributing to developing transformative, curative therapies for incurable diseases, with a strong sense of purpose and impact.
- **Culture & Values**: Described as supportive, collaborative, and intellectually curious. The team is interdisciplinary (scientists, engineers, entrepreneurs) and globally diverse.
- **Compensation & Benefits**: Competitive salary, stock options, fully paid extended healthcare for employee and family, life insurance, AD&D, parental leave top-up, annual professional development allowance, health & wellness spending account.
- **Work-Life Balance**: Minimum 3 weeks' vacation plus a December holiday break, flexible work hours.
- **Work Environment**: On-site roles in Vancouver, BC. Office features collaboration spaces, board games, video games, employee-led groups (book club), nearby walking/cycling routes, underground bike cages, and on-site showers.
- **Culture**: Described as supportive, collaborative, intellectually curious, and mission-driven. Employees report feeling they make a meaningful impact. The team is interdisciplinary and globally diverse.
- **Recognition**: Named one of Canada's Best Employers for Recent Graduates, Life Sciences BC Company of the Year 2024, BIOTECanada Biotech Company of the Year, and Fast Company Next Big Things in Tech.

## Sources
1. [aspectbiosystems.com](https://www.aspectbiosystems.com/)
2. [aspectbiosystems.com/about](https://aspectbiosystems.com/about)
3. [aspectbiosystems.com/careers](https://aspectbiosystems.com/careers)
4. [job-boards.greenhouse.io/aspectbiosystems](http://job-boards.greenhouse.io/aspectbiosystems)
5. [linkedin.com/company/aspect-biosystems](https://ca.linkedin.com/company/aspect-biosystems)

## Other roles at Aspect Biosystems

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- [Procurement Specialist](https://feeny.ai/job/procurement-specialist-aspect-biosystems-vancouver-9rpfgdhyvhnk) — Vancouver, Canada
- [Quality Assurance Specialist](https://feeny.ai/job/quality-assurance-specialist-aspect-biosystems-vancouver-7mta1vv2hgk0) — Vancouver, Canada
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- [Associate, Process Development (Cells)](https://feeny.ai/job/associate-process-development-cells-aspect-biosystems-vancouver-dnarb66fc5q4) — Vancouver, Canada
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- [Manufacturing Technician](https://feeny.ai/job/manufacturing-technician-aspect-biosystems-fremont-zgfry24v70h9) — Fremont, CA
- [General Application](https://feeny.ai/job/general-application-aspect-biosystems-vancouver-kqv4f0g8qc6h) — Vancouver, Canada