---
title: 'Director, Clinical Pharmacology at relationrx'
canonical: 'https://feeny.ai/job/director-clinical-pharmacology-relationrx-london-wpw6zyh37q45'
type: 'job'
last_seen: '2026-09-11'
---

# Director, Clinical Pharmacology at relationrx

- **Company:** relationrx
- **Location:** London, United Kingdom
- **Employment:** full-time
- **Posted:** 2026-08-25
- **Last confirmed live:** 2026-09-11
- **Apply:** https://jobs.ashbyhq.com/relationrx/9408dde4-e883-4003-bc8e-19c511195c54

## Job description

## About Relation

Relation is a sector defining TechBio company developing transformational medicines, with technology at our core. Our ambition is to understand human biology in unprecedented ways, discovering therapies to treat some of life’s most devastating diseases. We leverage single-cell multi-omics from patient tissue, functional assays, and machine learning to drive disease understanding, from cause to cure. We are scaling rapidly and building a team of exceptional individuals to push the boundaries of drug discovery. You will work in highly interdisciplinary teams where biology, computation, and engineering come together to solve complex problems that have not been solved before. Our state-of-the-art wet and dry labs in the heart of London are designed to accelerate this integration and translate insight into impact. We are committed to building diverse and inclusive teams. Relation is an equal opportunities employer and does not discriminate on the basis of gender, sexual orientation, marital or civil partnership status, gender reassignment, race, colour, nationality, ethnic or national origin, religion or belief, disability, or age. By joining Relation, you will help define how medicines are discovered and deliver meaningful impact for patients.

The opportunity Relation is offering an outstanding opportunity for a Director Clinical Pharmacology to help drive our growing discovery and development portfolio. This role will power translation, continuously improve the accuracy of predictions and accelerate the development of novel medicines. You will work across Translational Safety, in vivo Pharmacology and Biomarkers to drive end-to-end asset development across the entire value chain — from target assessment through to clinical support — continuously improving predictive accuracy and optimising dosing strategies for the target patient populations. Sitting within Relation's Drug Discovery team, this position is deeply embedded within cross-functional matrix project teams and will support multiple disease areas as our portfolio grows. In this position, you will play a critical role in the scientific advancement of nonclinical and clinical programmes by serving as the core quantitative and clinical pharmacology lead within project teams. You will drive all aspects of clinical pharmacology across all development phases and strategically apply Model-Informed Drug Development (MIDD) approaches to understand and translate non-clinical PK/PD into human drug development strategies, optimise trial design, justify dose selections, inform development decisions and mitigate risk across early and late-stage development. Your scope will be modality-agnostic, giving you oversight that spans small molecules, large molecules, and novel platforms. The role is a hybrid role based at our state-of-the-art facility in the heart of London.

Day to day, you will

- Build and own the clinical pharmacology and pharmacometric capability to support Relation's product development goals, setting standards for excellence and championing innovative approaches to drive data-informed decisions.
- Act as the Clinical Pharmacology lead for multiple concurrent programmes across indications and therapeutic modalities. Oversee clinical pharmacology input into study design across the full range of development, with an initial focus on IND-enabling and dedicated Phase 1 clinical pharmacology trials, eventually leading into Phase 2 and 3 trials.
- Work across Translational Safety, Translational Pharmacology and Biomarkers to integrate nonclinical and clinical data, continuously improving predictive accuracy.
- Lead modelling and simulation approaches, non-clinical to clinical PK/PD, DDI risk assessment, PBPK, population PK/PD and QSP approaches to characterise developability, exposure-response relationships, support dose and regimen selection and define quantitative criteria for data-driven decisions.
- Lead and manage external collaborations and CRO partnerships, ensuring effective execution, clear prioritisation and delivery against timelines, budgets and project goals.
- Author relevant sections of regulatory documents, including Investigator's Brochures, INDs and NDA/BLA/MAA submissions serving as the clinical pharmacology expert in interactions with regulators.
- Proactively identify and incorporate emerging AI-enabled approaches into clinical pharmacology workflows, using data analytics and evidence-based tools to sharpen decision-making.
- Interface closely with cross-functional teams, including DMPK, translational safety and toxicology, biology, clinical operations and regulatory affairs, to ensure clinical pharmacology considerations are embedded in development plans.
- Translate quantitative and biology data into clear, actionable insights, communicating findings effectively to project teams and senior stakeholders.
- Maintain rigorous documentation standards across modelling packages, protocols, and study reports.
- Champion Relation's collaborative, ambitious and science-driven culture, sharing quantitative expertise across the team and helping build an outstanding drug discovery organisation.

Professionally, you will have

- A PhD, PharmD, or MD with a specialisation in DMPK, Pharmacometrics, in vivo/Clinical Pharmacology, or a related scientific discipline, or equivalent industry experience in a lead Quantitative Clinical Pharmacology position.
- Significant experience in the pharmaceutical or biotech industry in Quantitative Clinical Pharmacology, spanning all stages of development. You will have a strong understanding of drug discovery, non-clinical and clinical development with a proven track record of applying Model-Informed Drug Development (MIDD) principles. Experience across therapeutic modalities, small molecules, biologics and novel platforms alike, would be beneficial.
- A strong foundation of in vivo Pharmacology and Clinical Pharmacology principles and quantitative drug development, with demonstrable experience applying advanced quantitative modelling (proven proficiency in core pharmacometric software such as NONMEM, R, Monolix, WinNonlin, GastroPlus, SimCyp), data analytics, and emerging AI-enabled approaches to support evidence-based decision making. You understand the regulatory landscape and how to integrate diverse data (nonclinical, translational and clinical) for efficient development.
- Outstanding communication skills, with a clear ability to translate complex quantitative data into actionable strategic messages for cross-functional teams, stakeholders and senior leadership.

Personally, you

- Are comfortable working in a matrixed environment, balancing multiple stakeholders and contributing effectively across teams.
- Take ownership of your work, proactively seek opportunities to contribute, and enable others to do their best work.
- Communicate openly and directly, give and receive feedback constructively, and handle challenging conversations with respect.
- Actively seek out diverse perspectives, build strong working relationships, and contribute to shared goals across teams.
- Embrace challenges with openness and resilience, set high standards for yourself, and strive to deliver meaningful outcomes.

Working Style & Culture at Relation At Relation, we operate in a matrixed, interdisciplinary environment, where impact is driven through collaboration across scientific, technical, and operational domains. We collaborate, and you will partner with colleagues across multiple teams and projects, contributing your expertise while aligning to shared company priorities. We work together and win together! The patient is waiting!

Recruitment Agencies Please note that Relation does not accept unsolicited resumes from agencies. Resumes should not be forwarded to our job aliases or employees. Relation will not be liable for any fees associated with unsolicited CVs.

## About relationrx

## Company Overview
- **One-liner**: Relation Therapeutics is an end-to-end biotech company using single-cell multi-omics and machine learning to discover and develop transformational medicines for devastating diseases.
- **Entity Type**: Private (Seed/venture-backed; total funding $139M)
- **Headquarters**: London, United Kingdom (with offices in Miami Beach, US, and presence in Italy & India)
- **Founded**: 2019
- **Founders**: Charles Roberts, Benjamin Swerner, and Jake Taylor-King

## Core Business
- **Primary industry**: Biotechnology / Drug Discovery & Development
- **Target customers**: B2B – partnerships with large pharma (Novartis, GSK, Deerfield); ultimately patients for its own pipeline
- **Mission**: “Understand human biology in an unprecedented way; discovering therapies that will treat some of life’s most devastating diseases. We leverage single-cell multi-omics directly from patient tissue, functional assays and machine learning to drive disease understanding — from cause to cure.”

## Products & Services
- **Lab-in-the-Loop Platform**: An integrated technology stack combining single-cell analysis, genomics, and machine learning to identify druggable targets and develop transformational medicines.
- **Pipeline**: Preclinical/early-stage programs in osteoporosis (first indication announced March 2023) and atopic diseases (strategic collaboration with Novartis announced December 2025). Further undisclosed programs advanced via partnerships with GSK and Deerfield Management.

## Market Standing
- **Valuation**: Not publicly disclosed
- **Key Metric**: Total funding of $139M (as of 2026); annual revenue estimated at $1.5M (LinkedIn estimate)
- **Notable Investors/Partners**:
  - DCVC, N Ventures (NVIDIA), Magnetic Ventures, Khosla Ventures, Firstminute Capital, Meltwind, Hitachi Ventures, ARK Invest
  - Strategic partners: Novartis (collaboration on atopic diseases), GSK ($15M equity investment and partnership), Deerfield Management (collaboration to form new companies from targets)
  - Grant from Bill & Melinda Gates Foundation (2020)
- **Growth Signals**:
  - Headcount grew 51.8% YoY to ~97 employees (LinkedIn)
  - Opened new labs in London (opened Feb 2023 by Nobel laureate Sir Paul Nurse)
  - Access to NVIDIA’s CAMBRIDGE-1 supercomputer
  - Multiple new funding rounds: $25M seed (June 2022), $35M seed-2 (March 2024), $15M from Novartis (Dec 2024), $26M further investment (2026)
  - Active job postings: 17 positions (as of mid-2026), with monthly postings up 54.5%

## Competitive Advantages
- **Differentiated platform**: Proprietary “Lab-in-the-Loop” approach that integrates wet-lab single-cell assays with machine learning, enabling high-resolution target discovery directly from patient tissue.
- **Top-tier compute**: Exclusive access to NVIDIA’s most powerful UK supercomputer and deep partnerships with NVIDIA, Mila, and academic leaders.
- **World-class talent**: Scientific advisory board includes Nobel laureate-level researchers and professors from MIT, Stanford, ETH Zurich, and Oxford; team drawn from GSK, BenevolentAI, Wellcome Sanger, and top universities.
- **Pharma validation**: Strong collaboration and equity investments from Novartis, GSK, and Deerfield signal confidence in the platform and pipeline.

## Strategic Focus
- **Priority areas**: Advancing internal pipeline in osteoporosis and atopic diseases; expanding collaborations with pharma to co-develop novel therapeutics; continuing to invest in AI/ML capabilities and single-cell technology.
- **Growth direction**: Scaling the team (especially in machine learning, data science, and biology), forming new spin-out companies with Deerfield, and deepening the use of generative AI for drug design.

## Why Work Here
- **Culture**: Emphasizes collaboration, empowerment, compassionate candor, and a winning attitude. “We set ambitious goals pushing boundaries with a high-performing mindset.”
- **Team**: Highly interdisciplinary – biologists, ML engineers, data scientists, computational chemists, and drug developers working together under one roof.
- **Location**: London HQ with hybrid possibility for some roles; research roles require on-site lab work (lab in King’s Cross area).
- **Perks**: Not publicly detailed, but the company offers the chance to work on cutting-edge AI + biology problems, access to NVIDIA supercomputing, and the impact of bringing new medicines to patients.
- **Engineering/Research Culture**: Strong focus on open collaboration with academia (e.g., Mila, Scripps, Gates Foundation); active hiring for senior ML scientists, computational biologists, and data engineers.

## Sources
1. [relationrx.com](https://www.relationrx.com/)
2. [relationrx.com/careers](https://www.relationrx.com/careers)
3. [relationrx.com/about](https://www.relationrx.com/about)
4. [LinkedIn – Relation Therapeutics](https://uk.linkedin.com/company/relation-therapeutics)
5. [jobs.ashbyhq.com/relationrx](https://jobs.ashbyhq.com/relationrx)

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