---
title: 'Director, Clinical Trial Liaison West at Kardigan'
canonical: 'https://feeny.ai/job/director-clinical-trial-liaison-west-kardigan-united-states-t8xmqj8mg16m'
type: 'job'
last_seen: '2026-09-12'
---

# Director, Clinical Trial Liaison West at Kardigan

- **Company:** Kardigan
- **Location:** United States
- **Compensation:** $253k–$329k
- **Work type:** remote
- **Posted:** 2026-09-01
- **Last confirmed live:** 2026-09-12
- **Apply:** https://job-boards.greenhouse.io/kardigan/jobs/5412246008

## Job description

## About Us

Kardigan is a heart health company working to make cardiovascular disease preventable, curable and no longer the leading cause of death in the world.

It is Kardigan’s mission to develop multiple targeted treatments in parallel that bring people with cardiovascular diseases to the cures they deserve.

Led by Tassos Gianakakos, Jay Edelberg, M.D., Ph.D., and Bob McDowell, Ph.D., Kardigan’s co-founders have reunited after leading MyoKardia to discover and develop mavacamten, the first cardiac myosin inhibitor, resulting in an acquisition by Bristol Myers Squibb in 2020.

We have a cutting-edge discovery and translational research platform, a pipeline of late-stage candidates, and an industry-leading team that is driven to improve the lives of patients.

At Kardigan, we are motivated by our values which guide how we work, interact, and achieve our goals. Driven by patients and their families, we are deeply committed to improving the lives of patients and prioritizing their needs above all else. We believe in being authentic—leading with truth to bring out the best in others by creating an environment where every person knows they will be fully accepted. With an eagerness to learn, we encourage the highest levels of curiosity and are open to changing our minds. We are committed to winning as a team with urgency, excellence, and intention, and support each other no matter what role we play or where we sit. Lastly, we strive to enable the impossible because patients are counting on us. We are not afraid to take risks to unlock innovation and advance scientific discoveries.

These values are the foundation of our work, empowering us to make a real difference, every day.

## Job Title: CLINICAL TRIAL LIAISON (CTL)

Level: Director

Region: West - South San Francisco, Los Angeles, San Diego

Reports to: Senior Director or above, Clinical Operations

The Clinical Trial Liaison (CTL) will develop relationships with clinical trial investigators and research site staff to facilitate recruitment of subjects in Kardigan clinical trials.  The Clinical Trial Liaison (CTL) supports Global Development clinical study execution as the local field-based representative for Kardigan in one or more countries/regions supporting clinical development programs. The CTL interacts with investigator sites and other parties related to clinical trial execution.  Depending on trial needs and status, some periods will involve extensive travel, up to 70%, to support site teams, troubleshoot challenges, and foster strong, collaborative relationships.

The CTL provides regional and country specific insights to support study feasibility, site identification and selection, and patient recruitment and retention initiatives. In collaboration with the study team, the CTL both identifies and helps facilitate resolution of investigator site issues.

The CTL will work in concert Kardigan’s clinical trial teams to ensure that investigators and site staff have a thorough scientific understanding of the investigational agents being used in the study, the trial’s eligibility criteria, and all study procedures. Particular attention will be given to assessing the effectiveness of each site’s strategy used to identify potentially eligible subjects. The CTL must also understand how the trial fits into the site’s pattern of treatment for the condition and how any competing clinical trials or upcoming drug approvals may affect the progress of recruitment. Repeated interactions will be needed over the course of the trial to ensure that the trial remains “top of mind” with investigators and staff. The CTL will function as part of the study and CRO teams. Furthermore, the CTL will serve as liaison with key investigators to help ensure that they receive assistance with any queries and that any concerns they have are promptly transmitted to the trial’s sponsor.

Duties and Responsibilities:

- Provide country/regional operational insight into site feasibility and selection and overall patient recruitment strategy
- Identify and cultivate high-quality cardiovascular investigators
- Communicate scientific and clinical information clearly and accurately, ensuring sites understand study objectives, rationale, investigational product profile, and any updates or amendments.
- Collaborate with Clinical Operations and Clinical Development
- Participate in clinical study team meetings and quality meetings where necessary providing input to study teams on operational issues based on site visits and contacts
- Attend and present at SIVs, investigator meetings, monitor workshops/training
- Participate in site visits with investigator site staff and/or CRO representatives, or independently, in support of clinical trial execution and report back to study teams e.g. feasibility, startup activities, enrolment or escalated study/site issues
- Support enrollment and retention efforts through tailored discussion, data-driven insights, and strong relationship-building
- Responsible for review, documentation and follow up of investigator site issues including tracking metrics
- Provides sponsor regional operational support and acts as point of escalation for investigator sites as appropriate
- Identify and escalate site needs, barriers, or operational challenges to the Clinical Operations and Medical teams.
- Participate in Regulatory GCP inspections and/or audits at investigator sites as sponsor representative
- Complete all administrative responsibilities consistent with SOPs and departmental guidelines including but not limited to required training, field activity documentation, expense reporting, and other assigned tasks
- Understand the scientific basis of assigned clinical trials
- Support creation of educational materials to effectively communicate the science behind the clinical trial
- Be able to communicate the scientific basis of the trials to other team members, investigators and site staff
- Identify effective prescreening strategies for each trial and recommend improvements
- Provide detailed reports of interactions with investigators and site staff
- Partner with Medical Affairs, Clinical Operations, and other cross-functional stakeholders to ensure consistent messaging and aligned site support.
- Ensure all interactions comply with regulatory, ethical, and company standards.

Qualifications and Experience:

- Minimum Bachelor’s degree, master’s preferred or terminal degree (MD, PhD or PharmD)
- 10+ years relevant industry and/or CRO experience required
- Extensive experience in site facing clinical trial operations required
- Cardiovascular clinical trial experience and expertise in cardiovascular disease (e.g., heart failure, cardiomyopathies, hypertension, cardiometabolic disease, etc.) preferred
- Extensive medical and scientific knowledge and clinical development understanding
- Excellent communicator of technical and scientific information
- Excellent interpersonal skills and demonstrated collaborative as well as independent working style
- Ability to build relations with the external medical community
- Proactive and self-motivated, ability to align activities with the clinical development plans (CDPs)
- Strong organizational skills with effective use of time and prioritization
- Cross cultural awareness
- Fluency in English and in local language in country of residence required
- A working knowledge of ICH/GCP
- Computer skills including Excel, Word, and PowerPoint
- A willingness to travel frequently within assigned geographical territory, including overnight travel.
- Valid driver’s license

*Salary range posted is reflective of MD candidates.  Salary will be adjusted for non-MD candidates

Exact Compensation may vary based on skills, experience and location.

Pay range $253,000—$329,000 USD

## About Kardigan

## Company Overview
- **One-liner**: Kardigan is a publicly traded biopharmaceutical company developing targeted cardiovascular therapies with the aim of transforming treatment from symptom management toward functional cures.
- **Entity Type**: Public (ticker not available from provided sources; IPO closed as per company announcement)
- **Headquarters**: South San Francisco, California, United States (with additional offices in Princeton, New Jersey and Chicago, Illinois)
- **Founded**: Year not specified in available sources
- **Founders**: Tassos Gianakakos (Co-Founder, CEO & Chair), Dr. Jay Edelberg (Co-Founder & Chief Medical Officer), Dr. Bob McDowell (Co-Founder & Scientific Adviser), Brianne Puglisi (Co-Founder)

## Core Business
- **Primary industry**: Biopharmaceuticals – cardiovascular drug discovery and development
- **Target customers**: B2B / B2G – healthcare providers, hospitals, payers, and patients; the company develops prescription medicines for serious cardiovascular conditions
- **Mission or purpose statement**: “To make cardiovascular disease preventable, curable and no longer the leading cause of death in the world.” ([kardigan.bio](https://www.kardigan.bio/))

## Products & Services
- **Tonlamarsen**: A Phase 2/3 candidate for acute severe hypertension (ASH) and uncontrolled hypertension. Positive Phase 2 data presented as a late-breaker at ACC.26 and simultaneously published in JACC. ([kardigan.bio](https://www.kardigan.bio/))
- **Danicamtiv**: A Phase 3 candidate for genetic dilated cardiomyopathy (DCM), targeting the underlying inherited cardiac muscle disease. ([kardigan.bio](https://www.kardigan.bio/))
- **Calcific Aortic Valve Stenosis (CAVS) Program**: A late-stage clinical program addressing calcium deposition that stiffens the aortic valve. ([kardigan.bio](https://www.kardigan.bio/))
- **Prolaio Subsidiary**: An AI and real‑world data platform integrated into Kardigan to generate insights, inform clinical trial design, and reduce time/cost of drug development. ([kardigan.bio](https://www.kardigan.bio/about-us/))
- **Cardiac Intelligence Platform**: A discovery and translational research engine that uses real‑world patient data, AI, and deep cardiovascular expertise to identify disease drivers and design targeted therapies. ([kardigan.bio](https://www.kardigan.bio/))

## Market Standing
- **Valuation/Market Cap**: Not disclosed in provided sources
- **Key Metric**: Public company (IPO closed); annual revenue not disclosed
- **Notable Investors/Partners**: Not explicitly listed in provided sources; company built on the team’s track record from MyoKardia (acquired by Bristol Myers Squibb for $13.1B in 2020)
- **Growth Signals**:
  - Positive Phase 2 pivotal data for Tonlamarsen in hypertension, presented at ACC.26 and published in JACC
  - Three late‑stage clinical programs (CAVS, ASH, DCM) running in parallel
  - Active job postings across 210+ roles in clinical operations, data science, manufacturing, and corporate strategy, indicating scaling ([job-boards.greenhouse.io/kardigan](http://job-boards.greenhouse.io/kardigan))
  - Integration of Prolaio’s AI platform to accelerate R&D

## Competitive Advantages
- **Leadership expertise**: CEO Tassos Gianakakos previously scaled MyoKardia from startup to a $13.1B acquisition; the team includes veterans from MyoKardia, Sanofi, BMS, and Merck.
- **Parallel pipeline strategy**: Multiple late‑stage programs targeting distinct cardiovascular diseases (valve, hypertension, cardiomyopathy) de‑risks development and creates data synergies.
- **Cardiac Intelligence platform**: Proprietary combination of real‑world data, AI, and deep biological insight to move beyond symptom management toward modifying underlying disease.
- **Focus on functional cures**: Each program aims to alter the course of disease rather than merely treat symptoms, creating potential for breakthrough efficacy.

## Strategic Focus
- **Advance late‑stage clinical trials**: Continue Phase 2/3 studies for Tonlamarsen, Danicamtiv, and CAVS while preparing for potential regulatory submissions.
- **Expand platform capabilities**: Leverage Prolaio’s AI and real‑world evidence to design smarter, faster trials and discover new drug targets.
- **Build commercial infrastructure**: Growing corporate strategy, medical affairs, and manufacturing teams in South San Francisco, Princeton, and Chicago signals preparation for launch.

## Why Work Here
- **Culture**: “Everything we do starts with patients – and it’s powered by people.” Emphasis on collaboration, purpose‑driven work, and achieving the impossible together. Mission‑oriented environment focused on curing cardiovascular disease. ([kardigan.bio](https://www.kardigan.bio/job-openings/))
- **Work model**: Roles are listed for South San Francisco, Princeton, NJ, and Chicago, IL; likely on‑site/hybrid given the lab and clinical development nature. Not purely remote.
- **Benefits**:
  - Competitive salaries and annual bonus program
  - Comprehensive medical, dental, and vision coverage
  - 401(k) plan, life and disability insurance
  - Flexible spending and health savings accounts
  - Commuter benefits, cellphone allowance
  - Paid holidays and time off
  - Employee assistance program ([kardigan.bio](https://www.kardigan.bio/job-openings/))
- **Engineering & data science culture**: Active recruitment for data analytics, AI, and clinical data science roles; Executive Director of Data, AI & Collaboration Services is an open position, reflecting a strong tech‑driven R&D approach.

## Sources
1. [kardigan.bio](https://www.kardigan.bio/) – Company homepage and pipeline descriptions
2. [kardigan.bio/about-us](https://www.kardigan.bio/about-us/) – About Us, mission, and Prolaio integration
3. [kardigan.bio/job-openings](https://www.kardigan.bio/job-openings/) – Careers page with benefits and open roles
4. [kardigan.bio/leadership](https://www.kardigan.bio/leadership/) – Leadership team and co‑founder backgrounds
5. [job-boards.greenhouse.io/kardigan](http://job-boards.greenhouse.io/kardigan) – Detailed job listings (32+ postings)

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