--- title: 'Director Data Management at Pedestal Health' canonical: 'https://feeny.ai/job/director-data-management-pedestal-health-united-states-em1ws5k0pbyt' type: 'job' last_seen: '2026-09-14' --- # Director Data Management at Pedestal Health - **Company:** Pedestal Health - **Location:** United States - **Posted:** 2026-08-10 - **Last confirmed live:** 2026-09-14 - **Apply:** https://job-boards.greenhouse.io/pedestalhealth/jobs/5384386008 ## Job description ## About Pedestal Health Pedestal Health (formerly Target RWE) combines deep health system partnerships, longitudinal data curation at scale, and modern study design to build continuous, high-quality evidence for life sciences organizations. The company partners with pharmaceutical and biotech companies, providers and payers to generate rigorous, multimodal evidence that supports clinical, regulatory and strategic decision-making across the full lifecycle of care. Pedestal Health is committed to advancing medical decision making to improve outcomes for patients. Pedestal Health is a Highlander Health company. Learn more at [pedestalhealth.com](http://pedestalhealth.com). ## The Role The Director, Data Management leads Pedestal Health's clinical data management (CDM) function across our prospective studies, clinical trials, external control arms, and registry cohorts. This is a hands-on leadership role responsible for the design and build of study databases, the standards that govern data collection, medical coding, and the delivery of analysis-ready, submission-grade datasets. The Director owns data quality, timelines, and regulatory compliance from study startup through database lock, and builds the people, processes, SOPs, and technology that let the function scale. ## What You’ll Do EDC Design & Build - Lead the design, build, configuration, and validation of Electronic Data Capture (EDC) databases (e.g., Medidata Rave, Veeva Vault CDMS, Oracle Clinical/InForm) across the study portfolio. - Own database specifications, edit checks, dynamics, derivations, and user-acceptance testing (UAT); ensure builds are validated and audit-ready prior to go-live. - Manage study startup, mid-study amendments, and database migrations with minimal disruption to sites and ongoing data flow. - Oversee integration of external and non-CRF data sources (labs, ePRO/eCOA, imaging, biomarkers, EHR-derived data) into the study database. CRF & Data Collection Standards - Author and maintain CRF/eCRF design guidelines, CRF Completion Guidelines, and a library of reusable standard forms aligned to CDISC CDASH. - Partner with clinical, biostatistics, and medical teams to translate protocols into efficient, high-quality data collection instruments. - Establish and govern data management standards, conventions, and SOPs to drive consistency and reusability across studies. Medical Coding - Oversee medical coding of adverse events, medical history, and concomitant medications using MedDRA and WHODrug. - Either lead coding in-house or manage and oversee a coding vendor - defining coding conventions, reviewing auto-encoding and manual review, resolving queries, and ensuring dictionary version control and supervising - Ensure coding accuracy, consistency, and timeliness, and reconcile coded terms with safety and clinical review. SDTM & ADaM / Regulatory Deliverables - Own the strategy and quality of CDISC-conformant deliverables, ensuring source data map cleanly to SDTM and support downstream ADaM datasets for statistical analysis and submission. - Direct the creation and review of SDTM datasets, annotated CRFs, define.xml, and the Study Data Reviewer's Guide (SDRG/cSDRG), and coordinate ADaM specifications with biostatistics/programming. - Run Pinnacle 21 (or equivalent) conformance checks and resolve findings to ensure FDA/EMA submission-readiness. Data Quality, Delivery & Compliance - Own end-to-end data cleaning, query management, discrepancy and SAE reconciliation, and database lock activities - delivering clean, on-time data. - Define and monitor data quality metrics, dashboards, and KPIs; report status and risks to study teams and leadership. - Ensure all activities comply with ICH-GCP, 21 CFR Part 11, applicable FDA/EMA regulations, and internal SOPs; support audits and inspections. Leadership & Vendor Management - Build, mentor, and manage a team of clinical data managers, programmers, and coders; set standards, allocate resources, and develop talent. - Manage CRO and technology vendors - scope, budgets, timelines, oversight, and quality - for outsourced data management and coding. - Contribute to proposals, timelines, and budgets, and represent data management with sponsors and partners. - Serve as SME and thought leader both inside and outside the organization. ## What You’ll Bring - Bachelor's degree in life sciences, health informatics, computer science, or a related field (advanced degree a plus). - 10+ years of clinical data management experience, including 3+ years leading or managing teams, in a pharma, biotech, CRO, or RWE setting. - Demonstrated, hands-on expertise building and validating EDC databases (Medidata Rave, Veeva, Oracle, or similar). - Proficiency with CDISC standards - CDASH, SDTM, and ADaM - and submission deliverables (define.xml, annotated CRF, reviewer's guides). - Experience overseeing medical coding with MedDRA and WHODrug, whether in-house or via a coding vendor. - Strong working knowledge of ICH-GCP, 21 CFR Part 11, and FDA/EMA regulatory requirements. - Proven ability to manage CROs and vendors, budgets, and multiple concurrent studies to deadline. ## Nice to Have - Society for Clinical Data Management (SCDM) certification (CCDM) or equivalent. - Experience with real-world evidence, registries, external control arms, or EHR-derived data. - Familiarity with Pinnacle 21, SAS, and/or data-review programming. - Therapeutic-area experience in hepatology, dermatology, or gastroenterology. ## What We Offer You - Hybrid work arrangement, with regular onsite collaboration at a Pedestal Health office - Comprehensive health, dental, and vision coverage - 401(k) with company match - Generous PTO and paid parental leave If you are ready to be part of a team where your work truly matters - where your expertise is valued, your growth is supported, and your contributions help shape the future of healthcare—Pedestal Health is the place for you. We’re building something meaningful together, and we’d love for you to be a part of it. Pedestal Health is an equal opportunity employer and seeks candidates from diverse backgrounds and abilities. ## About Pedestal Health ## Company Overview - **One-liner**: Pedestal Health is an integrated evidence generation partner for life sciences organizations, building continuous, longitudinal patient cohorts to support drug development, regulatory decisions, and clinical care. - **Entity Type**: Private (Part of Highlander Health, a venture-backed company co-founded by Amy Abernethy and Brad Hirsch) - **Headquarters**: Durham, North Carolina, USA - **Founded**: The company emerged from the rebranding of Target RWE and NoviSci, announced in May 2026. Target RWE was founded earlier; the current entity is the result of that merger. - **Founders**: Co-CEOs: Amy Abernethy, MD, PhD, and Brad Hirsch, MD ## Core Business - **Primary industry/industries**: Healthcare Technology, Real-World Evidence (RWE), Clinical Research, Life Sciences Data & Analytics - **Target customers**: Pharmaceutical and biotech companies, health systems, payers, and regulatory bodies (FDA/EMA). - **Mission or purpose statement**: To build a modern evidence-generation engine that reduces treatment access time by 50% through continuous evidence and personalized care, moving from episodic, start-from-scratch clinical studies to an infrastructure that compounds over time. ## Products & Services - **Longitudinal Real-World Data Cohorts**: Deeply phenotyped, disease-specific patient datasets (e.g., hepatology, dermatology, gastroenterology) built directly from clinical practice, continuously queried for safety, effectiveness, and regulatory studies. - **Regulatory-Grade Evidence Generation**: Full-service design and execution of externally controlled trials, prospective interventional studies, registries, and traditional real-world evidence studies for submission to FDA/EMA/HTA bodies. - **Headwater Science (Sister Company)**: A methodological and analytical engine offering deep expertise in causal inference, comparative effectiveness, healthcare utilization, and regulatory-grade analytical software. This is a separate but closely integrated entity within Highlander Health. ## Market Standing - **Valuation/Market Cap**: Not publicly disclosed. - **Key Metric**: Formed from the merger of two established companies (Target RWE and NoviSci) with strong existing revenue and partnerships; backed by Highlander Health, which is focused on evidence generation innovation. - **Notable Investors/Partners**: Highlander Health (the lead investor and parent company). Key health system partnerships are highlighted (e.g., University of North Carolina). - **Growth Signals**: Rebranding and strategic merger in May 2026 signals significant capital and strategic ambition. The company is actively hiring across multiple roles (engineering, data science, delivery, finance). Leadership includes former FDA Deputy Commissioner (Amy Abernethy) and founder of a successful clinical trial technology company (Brad Hirsch). ## Competitive Advantages - **Continuous Evidence Infrastructure**: Unlike traditional CROs or data providers, Pedestal builds **continuous** cohorts that compound over time, avoiding the "start from scratch" model for every new study. - **Deep Clinical Domanin Expertise**: Deepest footprint in hepatology, dermatology, and gastroenterology with pre-existing, deeply phenotyped patient populations and long-standing health system relationships. - **Regulatory & C-Suite Credibility**: Leadership team with unparalleled experience (former FDA Principal Deputy Commissioner, founders of successful healthcare tech companies, top clinical researchers). This translates into regulatory-grade outputs trusted by agencies. - **Integrated Methodological Engine (Headwater Science)**: Built-in access to world-class causal inference and data science expertise for complex analytical challenges, a significant moat against generalist competitors. - **Health System Embeddedness**: Data is sourced directly from clinical practice, offering a richer, more longitudinal picture of patient journeys than claims data alone. ## Strategic Focus - **Current priorities**: Expanding into new therapeutic areas beyond their core hepatology, dermatology, and GI strongholds. Scaling the "continuous evidence system" model across more biopharma partners. Integrating more deeply with health system IT for seamless data flow. - **Direction for growth**: Becoming the "evidence infrastructure" for the life sciences industry, moving from project-based work to platform-based, recurring partnerships. Focus on solving the most complex, high-stakes regulatory and access questions. ## Why Work Here - **Culture**: The company emphasizes passion, dedication, and use of patient data to shift the healthcare paradigm. They highlight "diverse and innovative perspectives" as core to their cutting-edge approach. - **Remote/Hybrid Policy**: **Hybrid work** is explicitly offered as a benefit. - **Notable Perks & Benefits**: - Competitive Health Insurance - **Paid Parental Leave** - Professional Development Courses - Employee Recognition Programs - Paid Holidays & Floating Holidays - **401(k) with Company Match & Immediate Vesting** - Paid Time Off - **Engineering/Data Science Culture**: At the intersection of clinical research, data science, and regulatory technology. The work directly impacts drug development timelines and patient access. The team includes world-class biostatisticians, epidemiologists, data engineers, and product managers. For those passionate about data for social impact in health, this is a mission-driven, fast-paced environment backed by deep expertise. ## Sources 1. [Pedestal Health Official Website](https://www.pedestalhealth.com/) 2. [About Us / Leadership](https://www.pedestalhealth.com/about/) 3. [Careers Page (Greenhouse)](https://job-boards.greenhouse.io/pedestalhealth) 4. [Pedestal Health Careers / Benefits](https://www.pedestalhealth.com/careers/) 5. [Yahoo Finance: Target RWE and NoviSci Rebrand as Pedestal Health and Headwater Science](https://finance.yahoo.com/sectors/healthcare/articles/target-rwe-novisci-rebrand-pedestal-110000567.html) ## Other roles at Pedestal Health - [Principal Data Scientist](https://feeny.ai/job/principal-data-scientist-pedestal-health-research-triangle-park-zgwh50nmz6gp) — Research Triangle Park, NC - [Senior Clinical Research Associate](https://feeny.ai/job/senior-clinical-research-associate-pedestal-health-research-triangle-park-mms5e1bjft8k) — Research Triangle Park, NC - [Study Start-up and Regulatory Manager](https://feeny.ai/job/study-start-up-and-regulatory-manager-pedestal-health-research-triangle-park-bvrc351c41c1) — Research Triangle Park, NC - [Data Engineer](https://feeny.ai/job/data-engineer-pedestal-health-research-triangle-park-ydmccp5n5c8e) — Research Triangle Park, NC - [Cloud Security Engineer (AWS)](https://feeny.ai/job/cloud-security-engineer-aws-pedestal-health-research-triangle-park-qy1h836f1dex) — Research Triangle Park, NC - [Senior AI/ML Engineer](https://feeny.ai/job/senior-ai-ml-engineer-pedestal-health-united-states-4z1bqhq3njgq) — United States