---
title: 'Director, Domestic Tax at Scholar Rock'
canonical: 'https://feeny.ai/job/director-domestic-tax-scholar-rock-cambridge-yssxb1zmhevd'
type: 'job'
last_seen: '2026-10-18'
---

# Director, Domestic Tax at Scholar Rock

- **Company:** Scholar Rock
- **Location:** Cambridge, MA
- **Compensation:** $200k–$260k
- **Employment:** full-time
- **Work type:** hybrid
- **Posted:** 2026-10-08
- **Last confirmed live:** 2026-10-18
- **Apply:** https://jobs.lever.co/scholarrock/de35f132-863a-4d38-964d-ff5865f42919

## Job description

Scholar Rock is delivering muscle-targeted breakthroughs to transform the treatment of spinal muscular atrophy (SMA) and other rare neuromuscular diseases where muscle atrophy remains a critical unmet need. As a global leader in myostatin biology, a field focused on proteins that regulate muscle mass, the biopharmaceutical company is named for the visual resemblance of a scholar rock to protein structures. Our commitment to unlock fundamentally different treatment approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. Scholar Rock works every day to create new possibilities for patients through its highly innovative anti-myostatin program, including opportunities in additional rare neuromuscular diseases. Learn more about our neuromuscular franchise at ScholarRock.com and follow @ScholarRock on X and on LinkedIn.

Summary of Position:

Position Responsibilities

U.S. Tax Provision and Financial Reporting

- Lead the U.S. federal and state components of the quarterly and annual income tax provision under ASC 740.
- Oversee current and deferred tax expense, domestic tax balance sheet accounts, effective tax rate items, tax account reconciliations, return-to-provision calculations, and provision-to-return adjustments.
- Own deferred tax calculations for net operating losses, research expenditures under Section 174, R&D and orphan drug credits, Section 163(j), fixed assets, stock-based compensation, clinical and compensation accruals, and other domestic temporary differences.
- Lead domestic valuation allowance and uncertain tax position analyses and maintain complete, audit-ready support.
- Support income tax disclosures, external audit requests, and management reporting related to domestic tax matters.

U.S. Federal and State Compliance

- Own the consolidated U.S. federal income tax return, including workpapers, elections, disclosures, estimates, extensions, payments, and filing governance.
- Incorporate U.S. international calculations and information returns as prepared by advisors or other members of the Tax team.
- Lead state and local income and franchise tax compliance, including combined, consolidated, unitary, and separate-company filings.
- Review nexus, apportionment, state modifications, filing methodologies, tax attributes, credits, incentives, and payment requirements.
- Maintain the domestic compliance calendar, data collection process, review standards, and oversight of external and co-sourced providers.

U.S. Tax Planning and Business Advisory

- Identify and implement U.S. federal and state tax planning opportunities aligned with the Company's strategy and risk profile.
- Advise on the U.S. tax treatment of R&D, clinical trials, research credits, Section 174 capitalization, stock-based compensation, executive compensation, manufacturing incentives, product launches, and commercial operations.
- Analyze licensing, collaboration, milestone, royalty, co-development, product acquisition, and commercialization arrangements from a domestic tax perspective.
- Monitor U.S. federal and state legislative developments, assess financial and operational impacts, and lead implementation.
- Prepare technical memoranda supporting material domestic tax positions and transactions.

Audits and Controversy

- Lead U.S. federal and state income and franchise tax examinations, notices, information requests, protests, appeals, settlement negotiations, and litigation support.
- Coordinate with the Vice President, Tax on examinations involving transfer pricing or U.S. international tax matters.
- Ensure examination outcomes are reflected in the provision, returns, forecasts, controls, and process improvements.

U.S. Sales and Use Tax and Other Domestic Indirect Taxes

Candidate Qualification

- Bachelor's degree in Accounting, Finance or Taxation, or a related field.
- CPA, MST, Master of Accounting, JD, or another relevant advanced credential.
- 12+ years of corporate tax experience with significant ASC 740 and domestic tax provision responsibility.
- Reviewer-level experience with consolidated U.S. federal and multistate income tax compliance.
- Strong knowledge of U.S. federal, state, and local tax law, including tax controversy.
- Experience overseeing U.S. sales and use tax compliance and audits.
- Experience leading or materially supporting an ERP implementation or major finance transformation.
- Strong understanding of SOX, tax controls, tax technology, and data governance.
- Strong project management, analytical, technical writing, and executive communication skills.

## Preferred Qualifications

- Combination of public accounting and in-house corporate tax experience.
- Public company and multinational biotechnology, pharmaceutical, medical device, or life sciences experience.
- Experience with R&D credits, Section 174, Section 163(j), stock-based compensation, state incentives, licensing, product launches, and domestic M&A.
- Experience with SAP, ONESOURCE, Corptax, Vertex, Avalara, Alteryx, or comparable tools.

Scholar Rock is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

## About Scholar Rock

## Company Overview
- **One-liner**: Scholar Rock is a biopharmaceutical company discovering and developing selective therapies targeting growth factors for serious diseases with high unmet need.
- **Entity Type**: Public (NASDAQ: SRRK)
- **Headquarters**: Cambridge, Massachusetts, United States
- **Founded**: 2012
- **Founders**: Not publicly available

## Core Business
- **Primary industry**: Biotechnology / Biopharmaceuticals
- **Target customers**: Patients suffering from neuromuscular disorders, cancer, fibrotic diseases, and hematologic conditions; healthcare providers and payers
- **Mission**: “Turning scientific discoveries into a pipeline of investigational therapies aimed at diseases where growth factors play a central role.”

## Products & Services
- **Apitegromab (SRK-015)**: A selective anti‑latent myostatin antibody in Phase 3 for spinal muscular atrophy (SMA). BLA resubmission and U.S. launch anticipated in 2026.
- **SRK‑181**: A selective anti‑latent TGFβ1 antibody for locally advanced or metastatic solid tumors (immuno‑oncology).
- **SRK‑373**: A context‑dependent anti‑latent TGFβ1 antibody for multiple fibrotic indications.
- **SRK‑256**: A selective anti‑RGMc/HJV antibody for hematology indications.
- **Proprietary Platform**: Broad technology for generating monoclonal antibodies that selectively target latent forms of growth factors (TGFβ superfamily).

## Market Standing
- **Valuation/Market Cap**: $2.8 B (as of search date, 2026‑09‑06)
- **Key Metric**: Annual revenue $0 (pre‑commercial); IPO in 2018
- **Notable Investors/Partners**: Not publicly available
- **Growth Signals**: Headcount grew 27.4% YoY to 278 employees; workforce across 7 countries; 20,522 LinkedIn followers (+45.9% yearly); first company to show clinical proof‑of‑concept for a muscle‑targeted treatment in SMA.

## Competitive Advantages
- First‑in‑class platform for selectively targeting latent growth factors (TGFβ superfamily), enabling high specificity and reduced off‑target effects.
- Proven clinical proof‑of‑concept in SMA with apitegromab, a novel mechanism.
- Broad pipeline spanning neuromuscular, oncology, fibrosis, and hematology, with multiple programs in Phase 2/3.

## Strategic Focus
- Advance apitegromab toward regulatory submission and commercial launch in SMA.
- Expand pipeline into cardiometabolic disorders and other growth‑factor‑driven diseases.
- Leverage platform to address historically under‑addressed disease areas.

## Why Work Here
- **Culture**: “Passion for science” and “every voice counts” – a collaborative, trust‑based environment focused on changing patients’ lives.
- **Work Policy**: Hybrid (e.g., Senior Director, Business Analytics in Cambridge, MA) and on‑site roles available.
- **Benefits**: Competitive health/dental/vision plans, life/AD&D insurance, short‑ and long‑term disability, paid parental leave, 401(k) match, financial wellness program, professional development, free parking/transit pass, onsite fitness center, weekly community lunches, peer‑to‑peer recognition.
- **Engineering/Science Culture**: Emphasis on innovation, cross‑functional teamwork, and direct impact on serious diseases.

## Sources
1. [scholarrock.com – Company Overview](https://scholarrock.com/our-company/careers/)
2. [scholarrock.com – Investors & Media](https://scholarrock.com/investors-media/)
3. [scholarrock.com – Pipeline](https://scholarrock.com/our-pipeline/)
4. [jobs.lever.co/scholarrock – Open Positions](https://jobs.lever.co/scholarrock)
5. [linkedin.com/company/scholar-rock – Company Profile](https://linkedin.com/company/scholar-rock)

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