--- title: 'Director, Field Medical - West at Maze Therapeutics' canonical: 'https://feeny.ai/job/director-field-medical-west-maze-therapeutics-united-states-1mkq4fhpegeg' type: 'job' last_seen: '2026-10-18' --- # Director, Field Medical - West at Maze Therapeutics - **Company:** Maze Therapeutics - **Location:** United States - **Posted:** 2026-09-16 - **Last confirmed live:** 2026-10-18 - **Apply:** http://www.mazetx.com/careers/?gh_jid=8815333002 ## Job description The Opportunity We’re looking for a Director of Field Medical to serve as the regional scientific lead during a pivotal stage of our growth. This senior, full-scope Medical Science Liaison role rests on two pillars: leading high-level scientific exchange and key opinion leader relationships across your region and serving as the field-facing scientific partner to Maze's clinical development programs. It’s a genuine scientific leadership position, not site support with a scientific veneer. With MZE829 entering its pivotal program in 2027 and MZE782 advancing through Phase 2, your immediate priority is enabling the clinical programs, so trial and investigator support carries real weight from day one. Because Maze is genetics-first, you’ll need credibility across two distinct communities: nephrology (AMKD, FSGS, CKD) and metabolic disease (PKU).  Initially, an individual contributor, you’ll build the region's scientific relationships and support trial execution, then help recruit, mentor, and eventually lead a regional MSL team as we grow The Impact You’ll Have Scientific Exchange & KOL Engagement You’ll be a recognized scientific expert and the trusted face of Maze in your regions. - Lead compliant, peer-to-peer scientific exchange with thought leaders, physicians, renal pathologists, and PKU specialists, and build a durable regional KOL map, including in a metabolic community where Maze isn’t yet known. - Provide accurate scientific education on AMKD, FSGS, CKD, and PKU, including APOL1 biology and SLC6A19 substrate reduction, and respond to unsolicited medical inquires. - Represent Maze at major congresses (ASN, NKF, and metabolic/PKU societies) and support advisory boards, scientific meetings, and patient advocacy partnerships. Clinical Development & Investigator Partnerships The immediate priority. You’ll be the field-facing scientific partner accountable for site engagement and scientific barriers affecting enrollment across your region. - Serve as the regional scientific partner to Maze's trials, including HORIZON and the MZE829, and MZE782, and the single point of contact for investigators and sites. - Shape site selection through feasibility input, and support site identification, investigator meetings, and start-up. - Own the field-side response to enrollment and retention barriers, driving compliant scientific solutions with Clinical Operations. Genetic Testing & Patient Identification - Support adoption of APOL1 genotyping and advance genotype-driven patient identification pathways, the mechanism by which eligible patients reach the trials. - Address the trust and access barriers facing an AMKD population disproportionately of African ancestry, a concrete enrollment lever, not a peripheral consideration. Medical Insights & Strategic Input - Capture field insight (treatment patterns, unmet need, evidence gaps, competitive intelligence) on a consistent cadence, and translate it into recommendations that shape medical strategy, evidence generation, and launch readiness.  Because Maze is small, these insights land directly with the people who set direction. Building the Field Medical Organization - Carry your assigned territory personally as the senior regional scientific leader, and help recruit, mentor, and develop MSLs as we scale, growing into regional team leadership over the next 1–2 years. As a Director, we also expect you to demonstrate the following Leadership Competencies: - Communication and Influence - Builds communication channels across Maze for sharing information - Influences Senior Management decisions through persuasive arguments - Respectfully addresses differing opinions leading to support of decision - Teamwork and Collaboration - Champions partnerships and connections across Maze - Proactively addresses issues that could result in breakdown of team relationships - Spotlights team and individual contributions in public forums - Execution and Results - Addresses gaps and leverages strengths to get best results - Maintains a steadying presence and clarifies priorities during change - Anticipates and removes barriers that put functional/corporate goals at risk - Develop Others and Self - Removes barriers to staff development and empowers them to make their own decisions - Stays current on industry trends and keeps direct-reports prepared and responsive ## What We’re Looking For What you’ll need - An advanced scientific degree (PharmD, PhD, MD, DO, or equivalent). - a minimum of 7 years of Medical Affairs, Field Medical, Clinical Development, or related biopharmaceutical experience. - A demonstrated track record building KOL relationships and leading peer-to-peer scientific exchange. This is a core requirement, not a nice-to-have; if you’re strong on trial logistics but light on scientific engagement and KOL relationships, this role isn’t the right fit. - Demonstrated accountability for site engagement and clinical trial enrollment, not solely data presentation at sites. - Deep scientific fluency and the credibility to hold a peer-level conversation with an academic specialist. - Willingness to travel approximately 60–70% within the assigned region. What would be great to have - Nephrology depth with existing relationships in the kidney community, and genuine willingness to build metabolic and PKU fluency. - Pre-commercial or first-launch biotechnology experience, built without an established field infrastructure. - Experience with genotype-driven patient identification and diagnostic testing pathways. - Experience mentoring MSLs or leading congress and or scientific-platform initiatives. ## About Maze Therapeutics Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing human genetics to develop precision medicines for patients with kidney and metabolic diseases. Our clinical pipeline is anchored by two small molecule programs: MZE829, an APOL1 inhibitor for patients with APOL1‑mediated kidney disease, and MZE782, which targets genetic drivers of disease in phenylketonuria (PKU) and chronic kidney disease. We are also advancing a preclinical pipeline through our Compass platform, which links human genetic variants to the biological pathways that drive disease. Our People Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients. Our Core Values Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission. Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others. Stand True – Our integrity is foundational; it guides us no matter the obstacle. The expected annual salary range for employees located in the San Francisco Bay Area is $205,000 - $295,000. Additionally, this position is eligible for an annual performance bonus. Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills, and job location. The expected salary range for this role may be modified in the future. Maze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy. #LI-Remote ## About Maze Therapeutics ## Company Overview - **One-liner**: Maze Therapeutics is a clinical-stage biopharmaceutical company developing small molecule precision medicines for common diseases, primarily kidney disease, by leveraging human genetics and its proprietary Compass platform. - **Entity Type**: Public (NASDAQ: MAZE) - **Headquarters**: South San Francisco, California, United States - **Founded**: 2018 - **Founders**: Not publicly listed as individual founders; the company was established by a team of geneticists and industry veterans. ## Core Business - **Primary industry/industries**: Biotechnology / Biopharmaceuticals (Precision Medicine) - **Target customers**: B2B (partners and investors), B2C (patients with APOL1-mediated kidney disease, chronic kidney disease, and phenylketonuria) - **Mission or purpose statement**: "Harnessing the power of genetics to transform the lives of patients" by translating genetic insights into effective precision medicines. ## Products & Services - **MZE829 (Lead Program)**: An oral, small molecule, dual-mechanism APOL1 inhibitor for the treatment of APOL1-mediated kidney disease (AMKD). Recently reported positive topline Phase 2 HORIZON trial data. - **MZE782 (SLC6A19 Inhibitor)**: A precision medicine in development for chronic kidney disease (CKD) and phenylketonuria (PKU), currently in clinical trials. - **Maze Compass™ Platform**: A proprietary platform that leverages variant functionalization to link genetic variants to disease pathways, enabling the discovery and design of precision medicines. - **Other Pipeline Programs**: Several additional programs in drug discovery targeting renal, cardiovascular, and metabolic diseases. ## Market Standing - **Valuation/Market Cap**: Approximately **$1.48 Billion** (as of mid-2026, per CB Insights market cap data). - **Key Metric**: **Total Raised** (including IPO): **$496 Million**. The company also announced a **$150 Million registered offering** in 2026. - **Notable Investors/Partners**: Key investors include **Third Rock Ventures**, **Gilead Sciences**, **Genentech**, **Denali Therapeutics**, and **Calico Life Sciences** (as top talent sources and likely institutional backers). The company went public via a PIPE/IPO structure. - **Growth Signals**: - Positive topline data from the Phase 2 HORIZON trial of MZE829 (announced March 2026). - Three clinical-stage programs and several discovery-stage programs. - Active job postings increased by **120% year-over-year**. - Headcount of approximately 150 employees (based on LinkedIn data showing ~150 total employees). ## Competitive Advantages - **Proprietary Compass Platform**: A unique, data-driven platform that functionally validates genetic variants, giving Maze a differentiated ability to identify and target disease-causing pathways that are often overlooked. - **Focus on Common Diseases**: Unlike many precision medicine companies that focus on rare diseases, Maze targets large, unmet medical needs (e.g., chronic kidney disease), which represents a massive market opportunity. - **Strong Genetic Foundation**: The company’s entire strategy is built on robust human genetic evidence, reducing the risk of late-stage clinical failures and increasing the probability of success. - **Experienced Leadership Team**: The team includes veterans from leading biotech and pharma companies (Gilead, Genentech, Amgen), providing deep industry expertise in drug development and commercialization. ## Strategic Focus - **Advance Lead Programs**: Primary focus is on progressing MZE829 through Phase 2/3 trials for APOL1-mediated kidney disease and advancing MZE782 for CKD and PKU. - **Expand Pipeline**: Leveraging the Compass platform to identify and develop additional precision medicines for renal, cardiovascular, and metabolic diseases. - **Clinical Data Generation**: Delivering key clinical readouts to support regulatory filings and potential partnerships. - **Commercial Preparation**: Building the infrastructure and team (e.g., Senior Director, Talent Acquisition; Senior Director, Pharmaceutical Development) to prepare for potential late-stage success and launch. ## Why Work Here - **Mission-Driven Culture**: The company is deeply committed to "harnessing the power of genetics to transform the lives of patients," with core values of "Impact Obsessed," "Stand True" (integrity), and "Further Together" (teamwork and resilience). - **Supportive Work Environment**: Maze promotes a culture that encourages "vision, initiative, and the development of talent," with a "stimulating atmosphere where people enjoy coming to work." - **Comprehensive Benefits**: Offers "comprehensive and competitive health, financial, paid time off and many other benefits designed to promote the health and financial well-being of employees and their families." - **Equal Opportunity Employer**: Committed to diversity and non-discrimination. - **Growth Trajectory**: As a public clinical-stage company with positive clinical data and a 120% increase in job postings year-over-year, there are significant opportunities for career growth and impact. - **Location**: Based in South San Francisco (a major biotech hub), though specific remote/hybrid policy is not publicly detailed. ## Sources 1. [mazetx.com](https://mazetx.com/) 2. [mazetx.com](https://mazetx.com/about-us/) 3. [mazetx.com](https://mazetx.com/careers/) 4. [cbinsights.com](https://www.cbinsights.com/company/maze-therapeutics) 5. [linkedin.com](https://www.linkedin.com/company/mazetx) ## Other roles at Maze Therapeutics - [Associate Director, CMC Project Management](https://feeny.ai/job/associate-director-cmc-project-management-maze-therapeutics-south-san-francisco-7wqp0jppgr7v) — South San Francisco, CA - [Director, Field Medical - East](https://feeny.ai/job/director-field-medical-east-maze-therapeutics-united-states-6gdfvzad7y1y) — United States - [Director, Field Medical - Central](https://feeny.ai/job/director-field-medical-central-maze-therapeutics-united-states-z7tsmyrg7bgf) — United States - [Senior Director, Information Technology](https://feeny.ai/job/senior-director-information-technology-maze-therapeutics-south-san-francisco-gzknm40mvm03) — South San Francisco, CA - [Manager, Chemical Development](https://feeny.ai/job/manager-chemical-development-maze-therapeutics-south-san-francisco-8x7qw5qcxd7k) — South San Francisco, CA - [Trial Master File Sr. Manager, Clinical Operations](https://feeny.ai/job/trial-master-file-sr-manager-clinical-operations-maze-therapeutics-south-san-qyae6d13b97b) — South San Francisco, CA - [Senior Project Manager, Clinical Operations](https://feeny.ai/job/senior-project-manager-clinical-operations-maze-therapeutics-south-san-francisco-tdcv9cmr2ey2) — South San Francisco, CA - [Director, Clinical Business Operations](https://feeny.ai/job/director-clinical-business-operations-maze-therapeutics-south-san-francisco-asppwh94sg0p) — South San Francisco, CA - [Director, Clinical Operations](https://feeny.ai/job/director-clinical-operations-maze-therapeutics-south-san-francisco-8bfjmd3vbqe7) — South San Francisco, CA - [Director, Medical Writing](https://feeny.ai/job/director-medical-writing-maze-therapeutics-south-san-francisco-8ar22n6wfbe9) — South San Francisco, CA