---
title: 'Director, HR Business Partnerships at Immunome, Inc.'
canonical: 'https://feeny.ai/job/director-hr-business-partnerships-immunome-inc-bothell-h367aqs4wkcc'
type: 'job'
last_seen: '2026-10-31'
---

# Director, HR Business Partnerships at Immunome, Inc.

- **Company:** Immunome, Inc.
- **Location:** Bothell, WA
- **Compensation:** $200k–$242k
- **Posted:** 2026-10-29
- **Last confirmed live:** 2026-10-31
- **Apply:** https://job-boards.greenhouse.io/immunomeinc/jobs/5467453008

## Job description

Company Overview

Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, supported by a leadership team with deep experience in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugates. Our pipeline includes varegacestat, an investigational gamma secretase inhibitor for which an NDA has been accepted by the U.S. FDA; IM-1021, a clinical-stage ROR1 ADC; IM-1617, a clinical-stage solid tumor ADC; and IM-3050, a clinical-stage FAP-targeted radioligand therapy. We are also advancing a broad portfolio of early-stage ADCs pursuing undisclosed solid tumor targets.

Position Overview

Immunome is seeking a strategic, collaborative, and hands-on Director, HR Business Partnerships to help shape and scale our people strategy as we advance the development of innovative cancer therapies.

Reporting to the Head of HR, this individual will play a foundational role in establishing Immunome's dedicated HR Business Partnership function. Initially serving as a hands-on strategic partner to business leaders, this individual will have the opportunity to build, lead, and develop a team of HR Business Partners as the organization grows.

This role is ideal for a seasoned HRBP practitioner who brings both strategic perspective and a willingness to roll up their sleeves. The successful candidate will serve as a trusted advisor to senior leaders, translating business priorities into practical people strategies that strengthen organizational effectiveness, build leadership capabilities, develop talent, and enable business performance.

Working collaboratively with HR colleagues and leaders across the company, this leader will help establish a proactive, consistent, and business-oriented approach to HR partnership at Immunome.

## Responsibilities

Strategic HR Business Partnership

- Serve as a trusted advisor to senior leaders across scientific, clinical, technical, and corporate functions. Build a deep understanding of Immunome’s business strategy and development priorities so you can anticipate people and talent needs.
- Translate business priorities into actionable people strategies that support performance, agility, and long-term growth.
- Coach and challenge leaders on complex people matters, bringing an objective perspective and practical solutions.
- Use workforce data, business insights, and external benchmarks to inform decisions and measure the impact of people initiatives.
- Develop a deep understanding of Immunome’s culture and values and help leaders model and reinforce them through how they build teams, make decisions, and manage change as the company grows.

Building the HRBP Function

- Partner with the Head of HR to define the HRBP function’s expectations, priorities, ways of working, and measures of success.
- Serve as a hands-on HRBP while setting up scalable practices, tools, and operating rhythms.
- As the organization grows, shape the HRBP team’s structure and capabilities, and hire, onboard, and develop future HR Business Partners.

Organizational Effectiveness and Leadership Development

- Assess organizational capabilities, clarify roles and accountabilities, and design structures that support effective execution and decision-making.
- Lead organizational effectiveness and change initiatives, including org design, team effectiveness, and leadership alignment. Balance business objectives, employee experience, and clear communication.
- Lead talent reviews, succession planning, performance calibration, and development planning with business leaders and Learning & Development.
- Coach leaders on performance management, feedback, and building high-performing teams to strengthen manager effectiveness and engagement.

HR Collaboration and Employee Relations

- Bring the business and employee perspective into the design, rollout, and ongoing improvement of HR programs, policies, and processes.
- Advise on sensitive employee relations matters, performance issues, and organizational risk, partnering with HR and Legal as needed.

## Qualifications

- Bachelor’s degree in Human Resources, Business Administration, Organizational Development, or a related field, or equivalent professional experience.
- 10+ years of progressive HR experience, including significant experience as a strategic HR Business Partner to senior leaders in a growing or evolving organization.
- Deep expertise in organizational design, workforce planning, talent management, leadership coaching, performance management, and change management.
- Experience coaching, mentoring, or leading HR professionals, with the interest and ability to build a team.
- Biotech or life sciences industry experience preferred.
- Advanced degree or relevant certification (e.g., SHRM-SCP, SPHR) preferred.

Knowledge and Skills

- Strategic and pragmatic: Brings a business-first perspective, connecting people priorities to business outcomes with a strong bias for action.
- Builder mentality: Energized by creating, improving, and scaling capabilities without unnecessary complexity.
- Player-coach orientation: Equally comfortable doing the work, coaching others, and leading a team as the function evolves.
- Comfort with ambiguity: Thrives in an evolving environment, bringing structure, clarity, and sound judgment.
- Influence and collaboration: Builds credibility and trusted relationships through partnership, constructive challenge, clear communication, and follow-through.
- Culture carrier: Embodies Immunome’s values and helps preserve and strengthen our culture as the organization scales.

What Success Looks Like

The successful candidate will:

- Establish trusted, proactive HR partnerships with senior leaders across the organization.
- Help define and demonstrate the value of strategic HR Business Partnership at Immunome.
- Translate business priorities into meaningful organizational and talent strategies.
- Strengthen leadership capabilities, organizational effectiveness, and talent planning.
- Build scalable HRBP practices that can support the organization's growth.
- Develop a strong foundation for a future HRBP team, with the ability to hire, coach, and lead that team as business needs evolve.
- Contribute to a collaborative, high-impact HR function that supports Immunome's business strategy and long-term success.

Washington State Pay Range $199,635—$242,000 USD

Join Our Experienced, Passionate Team

Working at Immunome gives you the opportunity to make a difference in the lives of cancer patients, contribute to developing best-in-class targeted cancer therapies, and work with some of the brightest and most experienced minds in antibody-drug conjugate (ADC) development.

Immunome’s office is charged with the collective excitement and passion of people working together to develop life-changing cancer medicines. Our team thrives in an innovative, collaborative environment where employees are empowered to do their best work.

Immunome also offers a comprehensive benefit program for you and your family, including:

- Medical, dental, and vision insurance coverage for employees and their dependents, including 100% company-paid medical premiums for employees
- A 401(k) with employer match
- Employer-paid life insurance, short- and long-term disability insurance, and AD&D
- Paid time off, company holidays, and a week-long winter break between Christmas and New Years.
- Paid parental leave

E/E/O

Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

E-Verify

Immunome, Inc. is a participant in E-Verify. Please review the following notices: [E-Verify Participation Poster](https://immunome.box.com/s/bopxukipfidxjscs4bjxt75f90bvpppk) | https://immunome.box.com/s/r51g9subw1wqni9xkutbl6up635sjr8e | https://immunome.box.com/s/r3ekbimwh988my9vzl76tnlbg60zvh9u.

## About Immunome, Inc.

## Company Overview
- **One-liner**: Immunome is a clinical-stage oncology company developing first-in-class and best-in-class targeted cancer therapies, with a primary focus on antibody-drug conjugates (ADCs).
- **Entity Type**: Public (Nasdaq: IMNM)
- **Headquarters**: Bothell, Washington, United States
- **Founded**: The company was formed through a merger of Morphimmune and Immunome in October 2023.
- **Founders**: The company is led by Clay Siegall, Ph.D. (Chairman, CEO, and President), who co-founded Seagen. The original Immunome entity was founded earlier, but the current company structure dates to the 2023 merger.

## Core Business
- Primary industry/industries: Biotechnology, Oncology, Drug Discovery & Development
- Target customers: Patients with cancer, healthcare providers, and clinical trial sites. The company is a B2B/B2C entity in the healthcare and life sciences space.
- Mission or purpose statement: "Our mission is to improve outcomes for cancer patients by advancing and expanding a portfolio of first-in-class and best-in-class therapeutic candidates." [immunome.com](https://immunome.com/)

## Products & Services
- **Varegacestat (formerly AL102)**: A late-clinical stage gamma secretase inhibitor for the treatment of desmoid tumors. The company submitted a New Drug Application (NDA) to the U.S. FDA in April 2026. [investors.immunome.com](https://investors.immunome.com/)
- **IM-1021**: A ROR1-targeted antibody-drug conjugate (ADC) currently in a Phase 1 trial.
- **IM-3050**: A FAP-targeted radioligand which received IND clearance in Q1 2025.
- **Preclinical ADC Pipeline (IM-1617, IM-1340, IM-1335)**: ADCs pursuing undisclosed targets with expression in multiple solid tumors. IM-1617 had its first patient dosed in a Phase 1 trial in June 2026. [investors.immunome.com](https://investors.immunome.com/)

## Market Standing
- **Valuation/Market Cap**: Not publicly available in the search results. As a public company, this fluctuates. (Check recent filings for current data).
- **Key Metric**: The company is pre-revenue (clinical-stage) and has raised significant capital. Since the 2023 merger, CEO Clay Siegall has raised $355 million in equity financings. [immunome.com](https://immunome.com/about/)
- **Notable Investors/Partners**: The company is publicly traded. Key leadership previously worked at Seagen (acquired by Pfizer for $43 billion).
- **Growth Signals**: The company is rapidly advancing its pipeline. Key milestones include the NDA submission for varegacestat, first patient dosed for IM-1617, and positive Phase 3 data presented at ASCO 2026. The company currently lists 32 open positions on its careers page, indicating strong hiring momentum. [job-boards.greenhouse.io](http://job-boards.greenhouse.io/immunomeinc)

## Competitive Advantages
- **World-Class Leadership**: The executive team, led by Seagen co-founder Clay Siegall, has deep experience in designing, developing, and commercializing blockbuster ADCs (ADCETRIS, PADCEV, TIVDAK, TUKYSA). [immunome.com](https://immunome.com/about/)
- **Proprietary ADC Platform**: A systematic, data-driven process for optimizing antibodies, linkers, and payloads to create differentiated ADCs. [immunome.com](https://immunome.com/)
- **Near-Term Catalyst**: The NDA submission for varegacestat provides a potential near-term commercial opportunity.
- **Strong Financial Backing**: Raised $355M in equity since the merger, providing a solid runway for pipeline advancement.

## Strategic Focus
- **Advancing the Pipeline**: The primary focus is on executing clinical trials for varegacestat (Phase 3), IM-1021 (Phase 1), and IM-3050 (Phase 1), and advancing preclinical ADCs into the clinic.
- **Regulatory Filing**: Successfully navigating the FDA NDA submission and potential approval for varegacestat.
- **Discovery & Expansion**: Using their ADC discovery platform to generate new candidates and identify and acquire targeted oncology assets to expand the portfolio. [immunome.com](https://immunome.com/about/)

## Why Work Here
- **Mission-Driven**: The work directly impacts the lives of cancer patients, with a stated goal of developing transformative therapies. [immunome.com](https://immunome.com/about/)
- **High-Impact Team**: Opportunity to work with "some of the brightest and most experienced minds in ADC development," including leaders who have brought multiple drugs to market. [immunome.com](https://immunome.com/careers/)
- **Growth Stage**: With 32 open roles, the company is in a rapid growth phase, offering significant career advancement opportunities. [job-boards.greenhouse.io](http://job-boards.greenhouse.io/immunomeinc)
- **Comprehensive Benefits**: Includes 100% company-paid medical premiums for employees, a 401(k) with employer match, paid parental leave, and a week-long winter break. [immunome.com](https://immunome.com/careers/)
- **Location & Culture**: Based in Bothell, WA. The company describes a culture of "innovative, collaborative environment where employees are empowered to do their best work." [immunome.com](https://immunome.com/careers/)

## Sources
1. [Immunome Official Website](https://immunome.com/)
2. [Immunome About Page](https://immunome.com/about/)
3. [Immunome Investor Relations](https://investors.immunome.com/)
4. [Immunome Careers Page](https://immunome.com/careers/)
5. [Immunome Jobs on Greenhouse](http://job-boards.greenhouse.io/immunomeinc)

## Other roles at Immunome, Inc.

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- [Senior Oncology Account Manager (Tennessee)](https://feeny.ai/job/senior-oncology-account-manager-tennessee-immunome-inc-nashville-t0h8vxtg3sm7) — Nashville, TN / Memphis, TN
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