---
title: 'Director, Information Technology at Replimune'
canonical: 'https://feeny.ai/job/director-information-technology-replimune-woburn-1mybctpvw619'
type: 'job'
last_seen: '2026-09-16'
---

# Director, Information Technology at Replimune

- **Company:** Replimune
- **Location:** Woburn, MA
- **Employment:** full-time
- **Work type:** hybrid
- **Posted:** 2026-09-11
- **Last confirmed live:** 2026-09-16
- **Apply:** https://jobs.ashbyhq.com/replimune/9c94a83b-6940-4cdd-9f21-7fca8ef6063b

## Job description

## Overview

Replimune’s mission is to revolutionize cancer treatment with therapies designed to activate a powerful and durable full-body anti-tumor response, boldly transforming cancer care because patient’s lives depend on it.

At Replimune, we live by our values:

United: We Collaborate for a Common Goal. Audacious: We Are Bold. Dedicated: We Give Our Full Commitment. Candid: We Are Honest With Each Other.

People are at the center of everything we do, and when it comes to our employees, we make it personal. With a deep sense of purpose, a strong and evolving culture, a competitive and forward-looking total rewards program, everyone at Replimune has a unique opportunity to impact on the lives of patients, caregivers and themselves.

Join us, as we reshape the future.

Position Summary

- The Director, IT Operations and Cybersecurity is responsible for leading the company's technology infrastructure, cybersecurity strategy, and day-to-day IT operations. This role ensures employees have reliable, secure, and scalable technology solutions that support business growth, scientific innovation, and regulatory requirements.
- As a senior leader, the Director partners with executives and business stakeholders to develop and execute technology and security strategies that align with organizational priorities. The role oversees IT operations, infrastructure, cybersecurity, service delivery, risk management, and business continuity while driving operational excellence across the organization.
- The ideal candidate combines strong leadership, strategic thinking, and operational execution, with experience building high-performing teams, managing vendor relationships, and delivering technology solutions in regulated environments. This individual will play a key role in safeguarding company information, supporting critical business functions, and enabling the company's long-term growth and success.
- This position is based in our Woburn office and welcomes hybrid work! Local candidates are expected to be on-site a minimum of 2 days per week.

## Key Responsibilities

- Lead the overall IT operations and cybersecurity strategy for the organization.
- Ensure secure, reliable, and scalable technology services that support business objectives.
- Partner with executive leadership to align technology investments with organizational priorities and risk tolerance.
- Build, mentor, and lead high-performing IT and cybersecurity teams.
- Oversee enterprise technology infrastructure, service delivery, and operational performance.
- Manage cybersecurity programs, risk management initiatives, and regulatory compliance requirements.
- Lead incident response, business continuity, and disaster recovery planning.
- Manage technology budgets, vendor relationships, and strategic partnerships.
- Drive continuous improvement, operational efficiency, and adoption of industry best practices.
- Support business functions across research, clinical, manufacturing, quality, commercial, and corporate operations.

## Preferred Skills and Experience

- 10+ years of progressive IT and cybersecurity leadership experience.
- Experience leading technology strategy, infrastructure, operations, and security programs.
- Proven success building and developing high-performing teams.
- Strong stakeholder management and executive communication skills.
- Experience working in regulated industries such as biotechnology, life sciences, healthcare, or pharmaceuticals preferred.
- Demonstrated experience operating at the senior level in complex, regulated, and research-driven environments.
- Deep understanding of enterprise and cloud security architectures, identity and access management, data protection, detection and response, and vulnerability management.
- Proven expertise in regulatory and assurance frameworks particularly in life sciences contexts.
- Pragmatic, risk-based approach to security that balances protection, usability, and scientific velocity.
- Experience supporting regulatory inspections and GxP audits.

Education and Certifications

- Bachelor's degree in Computer Science, Information Systems, Engineering, Life Sciences, Quality, or a related field.
- Certified Information Systems Security Professional certification, Certified Information Security Manager, Certified in Risk and Information Systems Control, or cloud security credentials strongly preferred.

Salary Range Replimune is committed to fair and equitable compensation practices, and we strive to provide employees with total compensation packages that are market competitive. For this role, the anticipated base pay range is $202,000-$261,500. The exact base pay offered for this role will depend on various factors, including but not limited to the selected candidate’s unique set of qualifications, skills, and experience. Our current organizational needs also play a part in determining your final offer.

At Replimune, base pay is only one part of your total compensation package. The selected candidate will be eligible for an annual performance incentive bonus, new hire equity, and ongoing performance-based equity. Replimune also offers various benefits offerings, including, but not limited to, medical, dental, and vision insurance, 401k match, flexible time off, and a number of paid holidays including year-end shutdown.

## About Replimune

Replimune Group, Inc., headquartered in Woburn, MA, was founded in 2015 with the mission to transform cancer treatment by pioneering the development of a novel portfolio of oncolytic immunotherapies. Replimune’s proprietary RPx platform is based on a potent HSV-1 backbone intended to maximize immunogenic cell death and the induction of a systemic anti-tumor immune response. The RPx platform is designed to have a unique dual local and systemic activity consisting of direct selective virus-mediated killing of the tumor resulting in the release of tumor derived antigens and altering of the tumor microenvironment to ignite a strong and durable systemic response. The RPx product candidates are expected to be synergistic with most established and experimental cancer treatment modalities, leading to the versatility to be developed alone or combined with a variety of other treatment options. For more information, please visit [www.replimune.com](http://www.replimune.com). We are an Equal Opportunity Employer.

## About Replimune

## Company Overview
- **One-liner**: Replimune is a clinical-stage biotech company focused on revolutionizing cancer treatment with a new class of oncolytic immunotherapies intended to activate a powerful and durable full-body anti-tumor response.
- **Entity Type**: Public (ticker not explicitly provided in search results, but company is publicly traded)
- **Headquarters**: Framingham, Massachusetts, USA (with additional locations in Woburn, MA and Oxfordshire, UK)
- **Founded**: 2015
- **Founders**: Robert Coffin, Ph.D. (Founder and Chief Scientist)

## Core Business
- **Primary industry**: Biotechnology – oncology, oncolytic immunotherapy
- **Target customers**: B2B (pharmaceutical partners) and ultimately patients through healthcare providers
- **Mission**: To ignite a systemic immune response to cancer and reshape the future of cancer care

## Products & Services
- **RPx Platform**: Proprietary, next-generation HSV-1-based oncolytic immunotherapy platform that powers all pipeline candidates.
- **RP1**: Investigational oncolytic immunotherapy for advanced melanoma (IGNYTE trial, PDUFA date April 10, 2026) and non-melanoma skin cancers; also being studied as monotherapy in organ transplant patients with skin cancer (ARTACUS trial).
- **RP2**: Investigational oncolytic immunotherapy for metastatic uveal melanoma (Phase 2/3 RP2-202 trial) and hepatocellular carcinoma (Phase 2 in combination with atezolizumab/bevacizumab).

## Market Standing
- **Valuation/Market Cap**: Not publicly available in provided sources
- **Key Metric**: Clinical-stage; no approved products yet. Key regulatory milestone: FDA action date for RP1 in advanced melanoma on April 10, 2026.
- **Notable Partners**: Bristol-Myers Squibb (supply of nivolumab), Roche (supply of atezolizumab and bevacizumab) – Replimune retains full commercial rights.
- **Growth Signals**: Completed enrollment in IGNYTE trial; confirmatory IGNYTE-3 trial underway; own 63,000 sq ft U.S. manufacturing facility in Woburn, MA enabling global commercial supply; broad pipeline across multiple solid tumor indications.

## Competitive Advantages
- **Strong IP position**: Wholly-owned, unencumbered RPx platform with broad patent protection.
- **In-house manufacturing**: Dedicated U.S. facility for commercial-scale production, reducing reliance on contract manufacturers.
- **First-mover potential**: Poised to be one of the first oncolytic immunotherapies to reach the market if RP1 gains FDA approval.
- **Full rights retained**: All partnership agreements allow Replimune to keep full commercial rights to its therapies.

## Strategic Focus
- Advancing RP1 toward FDA approval in advanced melanoma (April 2026 PDUFA date)
- Expanding pipeline into additional indications (uveal melanoma, hepatocellular carcinoma, non-melanoma skin cancers)
- Building out commercial infrastructure and manufacturing capabilities
- Exploring combination therapies with checkpoint inhibitors (nivolumab, atezolizumab)

## Why Work Here
- **Culture**: Cross-functional, collaborative, values-driven environment. Employee survey results show 92% proud to work at Replimune, 88% feel they make a positive difference, 78% would recommend the company.
- **Flexibility**: Hybrid and remote work options available depending on role; home office and mobile phone stipend provided.
- **Compensation**: New hire equity grants, generous annual bonus plans, retirement plans with substantial company match (100% vested from day one).
- **Benefits**: Medical, dental, and vision insurance 100% paid by the company.
- **Locations**: U.S. (Woburn, MA and Framingham, MA) and UK (Oxfordshire) – opportunities to work across both sites.

## Sources
1. [Replimune Homepage](https://www.replimune.com/)
2. [Replimune Careers](https://www.replimune.com/careers)
3. [Replimune About Us](https://www.replimune.com/about-us)
4. [Replimune Team](https://www.replimune.com/team)
5. [Replimune Pipeline](https://www.replimune.com/pipeline)

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