---
title: 'Director, Intellectual Property at Tango Therapeutics'
canonical: 'https://feeny.ai/job/director-intellectual-property-tango-therapeutics-boston-pesyhn9k10dj'
type: 'job'
last_seen: '2026-10-13'
---

# Director, Intellectual Property at Tango Therapeutics

- **Company:** Tango Therapeutics
- **Location:** Boston, MA
- **Compensation:** $198k–$298k
- **Posted:** 2026-10-02
- **Last confirmed live:** 2026-10-13
- **Apply:** https://job-boards.greenhouse.io/tangotherapeutics/jobs/8010873003

## Job description

Company Overview

Tango Therapeutics is a biotechnology company dedicated to discovering novel drug targets and delivering the next generation of precision medicine for the treatment of cancer.

Using an approach that starts and ends with patients, Tango leverages the genetic principle of synthetic lethality to discover and develop therapies that take aim at critical targets in cancer.

This includes expanding the universe of precision oncology targets into novel areas such as tumor suppressor gene loss and their contribution to the ability of cancer cells to evade immune cell killing.

The Tango labs and offices are located at 201 Brookline Avenue, in the Fenway area of Boston, Massachusetts.

Summary:

We are seeking a highly skilled, motivated attorney to join our team as Director, Intellectual Property. Reporting to the General Counsel, this role will lead Tango’s intellectual property function and manage all facets of IP through the various stages of product development. This role will implement the company’s intellectual property strategy in the oncology space, counsel internal clients, manage patent filing and prosecution, review publications, track regulatory exclusivities for each product, perform freedom to operate analysis, handle trademark prosecution, and oversee IP litigation. Further, this role will work closely with the Business Development team to support strategic transactions. This role offers a broad range of responsibilities and significant growth opportunities in an exciting and growing company.

Responsibilities:

- IP Strategy Development: Design and implement comprehensive IP strategies aligned with the company's R&D and business objectives.
- Portfolio Management: Oversee the global IP portfolio, including freedom-to-operate analyses, patentability assessments, and IP risk mitigation.
- Cross-functional collaboration: provide IP counseling to in-house clients within discovery and development functions such as chemistry, CMC, and other functional areas through all phases of drug research, development, and commercialization
- Strategic transaction support: Assist Business Development and Research teams with intellectual property aspects of transactional, licensing, and strategic agreements, including material transfer agreements, licensing agreements, and sponsored research agreements
- Patent applications and prosecution: Prepare patent applications (with the assistance of outside counsel); maintain prosecution docket of all U.S. and foreign patent applications, including post-grant practices as they may arise with prosecution
- Implement trade secret best practices to protect technology not subject to patent protection
- Actively contribute to the legal function by building a positive culture, fostering engagement, sharing best practices and participating in initiatives focused on building departmental and functional knowledge and competencies.

Education & Experience

- J.D. from an accredited law school and admitted to practice in at least one U.S. jurisdiction
- A minimum of 8-10 years of legal experience at a top-tier law firm and/or in a biotech company’s legal department
- In-house experience at an early-stage pharmaceutical/biotech company strongly preferred
- Licensing and technology transactional experience (including with co-development, co-commercialization, and/or distribution agreements) preferred
- Experience developing global IP strategy required, with the objective of supporting the development of a comprehensive commercial strategy to protect product exclusivity rights
- Must have direct experience drafting and prosecuting patent applications and conducting or directing Freedom to Operate analyses
- Ability to work independently and within a team environment
- Developed sense of judgment, risk management skills, and ability to balance legal matters involving multiple stakeholders and various priorities
- Ability to concisely, succinctly, and clearly communicate complex IP concepts and strategy to stakeholders with limited exposure to IP concepts
- Ability to interpret legal requirements and deliver pragmatic, business-oriented guidance
- Proven capability to manage multiple priorities and collaborative effectively in a fast-paced, collaborative environment
- Excellent verbal and written communication skills

We are an equal opportunity employer and value diversity at our company.

We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. Salary range $198,400—$297,600 USD

## About Tango Therapeutics

## Company Overview
- **One-liner**: Tango Therapeutics is a clinical-stage biotechnology company leveraging the principle of synthetic lethality to discover and develop next-generation precision cancer medicines for genetically defined patient populations.
- **Entity Type**: Public (NASDAQ: TNGX)
- **Headquarters**: Boston, Massachusetts, United States
- **Founded**: 2017
- **Founders**: Not publicly disclosed (launched by Third Rock Ventures)

## Core Business
- **Primary industry/industries**: Biotechnology, Precision Oncology, Drug Discovery & Development
- **Target customers**: B2B (pharma partnerships, clinical trial sites); ultimate customers are cancer patients with specific genetic tumor profiles
- **Mission or purpose statement**: "Discover transformative drugs for people with cancer by leveraging the classic principles of synthetic lethality in innovative ways… building a road map to cures that will transform the lives of patients and their families." [tangotx.com](https://www.tangotx.com/join-us/)

## Products & Services
- **Vopimetostat (PRMT5 inhibitor)**: A clinical-stage, wholly-owned program targeting MTAP-deleted cancers, including pancreatic, lung, and glioblastoma. Currently in Phase 1/2 trials. [tangotx.com](https://www.tangotx.com/pipeline/)
- **TNG456 (PRMT5 inhibitor)**: A next-generation PRMT5 inhibitor for MTAP-deleted cancers, currently in pre-clinical development.
- **Daraxonrasib (RAS inhibitor)**: A combination therapy (with vopimetostat) for MTAPdel/RASmut pancreatic and lung cancers. Recently reported a 92% objective response rate in pancreatic cancer in a Phase 1/2 trial. [tangotx.com](https://www.tangotx.com/)
- **CRISPR-based Target Discovery Engine**: A proprietary platform for identifying novel synthetic lethal targets, enabling a robust pipeline of wholly-owned programs.

## Market Standing
- **Valuation/Market Cap**: ~$1.05 billion (as of mid-2026) [linkedin.com](https://www.linkedin.com/company/tango-therapeutics)
- **Key Metric**: Annual Revenue of ~$62.4 million; Total Funding raised ~$901 million (including post-IPO). [linkedin.com](https://www.linkedin.com/company/tango-therapeutics)
- **Notable Investors/Partners**: Third Rock Ventures (lead Series A), Boxer Capital (lead Series B), BCTG Acquisition Corp (parent). Strategic partners include pharma and biotech companies (collaborations under active exploration). [linkedin.com](https://www.linkedin.com/company/tango-therapeutics)
- **Growth Signals**: Completed a $600 million upsized public offering in June 2026; strong clinical data (92% ORR in pancreatic cancer); pipeline expanding into glioblastoma; headcount growth in job postings (+400% YoY in active roles). [tangotx.com](https://www.tangotx.com/)

## Competitive Advantages
- **Synthetic Lethality Expertise**: A deep, proprietary understanding of CRISPR-based target discovery to identify novel vulnerabilities in cancers with tumor suppressor gene loss, undruggable oncogenes, and immune evasion mechanisms.
- **Genetically Defined Patient Selection**: All programs are designed for well-defined patient populations with clear biomarkers, increasing the probability of clinical success and reducing trial risk.
- **Wholly-Owned Pipeline**: Unlike many biotechs that license out rights, Tango retains full ownership of its lead programs, capturing maximum value.
- **Strong Financial Position**: With over $1B in market cap and a recent $600M offering, the company is well-capitalized to advance its pipeline through pivotal trials.

## Strategic Focus
- **Current priorities**: Advancing vopimetostat and daraxonrasib into Phase 3 trials for pancreatic and lung cancers; expanding the pipeline into glioblastoma; continuing to discover and validate new synthetic lethal targets; building out commercial manufacturing and clinical operations infrastructure.
- **Direction for growth**: Becoming a fully-integrated biotechnology company capable of bringing its own medicines to market, while selectively pursuing strategic collaborations to expand reach.

## Why Work Here
- **Culture highlights**: Emphasizes "urgency + compassion," "courage + leadership," "spirit + resilience," and "embrace individuality and face challenges together." Described as a team of "passionate problem solvers" who are "all in for exciting science and changing lives." [tangotx.com](https://www.tangotx.com/join-us/)
- **Remote/hybrid/office policy**: Primarily on-site at Boston HQ (201 Brookline Ave, Suite 901, Boston, MA). Roles appear to be Boston-based, though some field-based positions (e.g., Medical Science Liaisons) are remote.
- **Notable perks or engineering culture**: High scientific ambition with a clear patient-first mission; strong leadership team with deep oncology experience; active hiring across clinical operations, biostatistics, medical affairs, and legal/compliance; 15+ active job postings with significant YoY growth in roles. [greenhouse.io](http://job-boards.greenhouse.io/tangotherapeutics)
- **Workforce**: ~129 employees, with a mix of research (26%), medical (12%), and operations roles. Notable alumni from Novartis, Vertex, Takeda, and Broad Institute. [linkedin.com](https://www.linkedin.com/company/tango-therapeutics)

## Sources
1. [Tango Therapeutics Official Website](https://www.tangotx.com/)
2. [Tango Therapeutics Careers Page (Greenhouse)](http://job-boards.greenhouse.io/tangotherapeutics)
3. [Tango Therapeutics LinkedIn Profile](https://www.linkedin.com/company/tango-therapeutics)
4. [Tango Therapeutics Pipeline Page](https://www.tangotx.com/pipeline/)
5. [Tango Therapeutics Join Us Page](https://www.tangotx.com/join-us/)

## Other roles at Tango Therapeutics

- [Executive Director, Commercial Law/Commercial Contracts](https://feeny.ai/job/executive-director-commercial-law-commercial-contracts-tango-therapeutics-boston-4rgpv55eb66w) — Boston, MA
- [Senior Clinical Data Manager](https://feeny.ai/job/senior-clinical-data-manager-tango-therapeutics-boston-xk614h7zhf91) — Boston, MA
- [Manager, GMP Quality](https://feeny.ai/job/manager-gmp-quality-tango-therapeutics-boston-70t57986x902) — Boston, MA
- [Executive Director, Commercial Strategy & Execution](https://feeny.ai/job/executive-director-commercial-strategy-execution-tango-therapeutics-boston-y7x7vkeeenkd) — Boston, MA
- [Head of Marketing & Sales](https://feeny.ai/job/head-of-marketing-sales-tango-therapeutics-boston-ex81335qs4hc) — Boston, MA
- [Head of Insights & Analytics](https://feeny.ai/job/head-of-insights-analytics-tango-therapeutics-boston-4f5kkx80kztw) — Boston, MA
- [Senior Vice President, Market Access](https://feeny.ai/job/senior-vice-president-market-access-tango-therapeutics-boston-47tt1fw4qxxq) — Boston, MA
- [Executive Director, FP&A](https://feeny.ai/job/executive-director-fp-a-tango-therapeutics-boston-kph81hnp4jvk) — Boston, MA
- [Associate Director, Pharmacovigilance Scientist](https://feeny.ai/job/associate-director-pharmacovigilance-scientist-tango-therapeutics-boston-5cgk3mmdsprr) — Boston, MA
- [Associate Medical Director, Pharmacovigilance](https://feeny.ai/job/associate-medical-director-pharmacovigilance-tango-therapeutics-boston-4kcjnjy0vpys) — Boston, MA