--- title: 'Director, Medical Writing at Maze Therapeutics' canonical: 'https://feeny.ai/job/director-medical-writing-maze-therapeutics-south-san-francisco-8ar22n6wfbe9' type: 'job' last_seen: '2026-09-13' --- # Director, Medical Writing at Maze Therapeutics - **Company:** Maze Therapeutics - **Location:** South San Francisco, CA - **Posted:** 2026-07-22 - **Last confirmed live:** 2026-09-13 - **Apply:** http://www.mazetx.com/careers/?gh_jid=8633481002 ## Job description The Position Step into a pivotal role where science meets strategy. At Maze, we’re on a mission to uncover genetic insights and transform them into precision medicines that change lives. Our team is driven by curiosity, collaboration, and a commitment to improving treatment for people with severe diseases. We thrive on diverse perspectives and bold ideas, and we’re looking for someone who shares that spirit. As our Director of Medical Writing, you’ll lead the medical writing function and play a central role in the development of clinical and regulatory documents across Maze’s development programs. You’ll help ensure that documents are scientifically accurate, internally consistent, fit for purpose, submission-ready, and aligned with program objectives. Reporting to the Vice President of Regulatory and Quality Science, you’ll work closely with cross-functional and external partners to advance the planning, development, and readiness of clinical and regulatory deliverables. You’ll also manage Regulatory Operations and Regulatory Project Management resources that support Maze’s development programs. The Impact You’ll Have - Lead the medical writing function and be accountable for the development of high-quality clinical and regulatory documents across Maze’s development programs, including protocols, clinical study reports, health authority meeting materials, and submission-supporting content. - Manage medical writing vendors and external partners to ensure timely, high-quality deliverables that are aligned with Maze’s scientific, clinical, and regulatory expectations. - Ensure clinical and regulatory documents are internally consistent and appropriately reflect agreed program strategy, study objectives, clinical data, and health authority expectations. - Partner closely with Regulatory Affairs, Clinical Development, Biostatistics, Clinical Operations, Safety, Quality, CMC, and external partners to support development and finalization of clinical-regulatory deliverables. - Interpret and translate clinical study source materials, including protocols, SAPs, TFLs, and safety and efficacy outputs, into clear, accurate, and defensible regulatory documents with appropriate cross-functional input and alignment. - Establish and improve medical writing standards, templates, review practices, and process efficiencies to support scalable, high-quality regulatory document development. - Identify practical opportunities to use structured content, content reuse, automation, and AI-enabled tools to improve efficiency, quality, consistency, and regulatory readiness while maintaining appropriate human oversight and traceability. As a Director, we also expect our leaders to demonstrate the following Leadership Competencies: Leadership Competencies - Communication and Influence - Builds communication channels across Maze for sharing information - Influences Senior Management decisions through persuasive arguments - Respectfully addresses differing opinions leading to support of decision - Teamwork and Collaboration - Champions partnerships and connections across Maze - Proactively addresses issues that could result in breakdown of team relationships - Spotlights team and individual contributions in public forums - Execution and Results - Addresses gaps and leverages strengths to get best results - Maintains a steadying presence and clarifies priorities during change - Anticipates and removes barriers that put functional/corporate goals at risk - Develop Others and Self - Removes barriers to staff development and empowers them to make their own decisions - Stays current on industry trends and keeps direct-reports prepared and responsive ## What We’re Looking For - 8–10+ years of progressive regulatory medical writing experience in the biopharmaceutical industry; sponsor-side or sponsor-embedded experience preferred. - Advanced degree in a scientific, medical, or health-related discipline preferred; bachelor’s degree with significant relevant experience required. - Demonstrated experience with clinical and regulatory documents across the development lifecycle, with late-stage development and NDA/BLA/MAA experience preferred. - Strong understanding of drug development, clinical trial design, regulatory requirements, and FDA, ICH, EMA, and other applicable guidance for clinical-regulatory documents. - Ability to interpret and communicate clinical data clearly and accurately, including experience working with protocols, SAPs, TFLs, safety and efficacy outputs, and other clinical study source materials. - Experience managing external medical writing resources and working effectively with cross-functional teams in a hands-on development environment. - Practical familiarity with structured content, content reuse, document automation, AI-enabled tools, or other technologies that can improve efficiency, consistency, and quality in medical writing. This role follows a hybrid schedule, with an expectation to be onsite at our South San Francisco headquarters at least three days per week. ## About Maze Therapeutics Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing human genetics to develop precision medicines for patients with kidney and metabolic diseases. Our clinical pipeline is anchored by two small molecule programs: MZE829, an APOL1 inhibitor for patients with APOL1‑mediated kidney disease, and MZE782, which targets genetic drivers of disease in phenylketonuria (PKU) and chronic kidney disease. We are also advancing a preclinical pipeline through our Compass platform, which links human genetic variants to the biological pathways that drive disease. Our People Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients. Our Core Values Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission. Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others. Stand True – Our integrity is foundational; it guides us no matter the obstacle. The expected annual salary range for employees located in the San Francisco Bay Area is $223,000 - $271,000. Additionally, this position is eligible for an annual performance bonus. Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills, and job location. The expected salary range for this role may be modified in the future. Maze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy. #LI-Hybrid ## About Maze Therapeutics ## Company Overview - **One-liner**: Maze Therapeutics is a clinical-stage biopharmaceutical company developing small molecule precision medicines for common diseases, primarily kidney disease, by leveraging human genetics and its proprietary Compass platform. - **Entity Type**: Public (NASDAQ: MAZE) - **Headquarters**: South San Francisco, California, United States - **Founded**: 2018 - **Founders**: Not publicly listed as individual founders; the company was established by a team of geneticists and industry veterans. ## Core Business - **Primary industry/industries**: Biotechnology / Biopharmaceuticals (Precision Medicine) - **Target customers**: B2B (partners and investors), B2C (patients with APOL1-mediated kidney disease, chronic kidney disease, and phenylketonuria) - **Mission or purpose statement**: "Harnessing the power of genetics to transform the lives of patients" by translating genetic insights into effective precision medicines. ## Products & Services - **MZE829 (Lead Program)**: An oral, small molecule, dual-mechanism APOL1 inhibitor for the treatment of APOL1-mediated kidney disease (AMKD). Recently reported positive topline Phase 2 HORIZON trial data. - **MZE782 (SLC6A19 Inhibitor)**: A precision medicine in development for chronic kidney disease (CKD) and phenylketonuria (PKU), currently in clinical trials. - **Maze Compass™ Platform**: A proprietary platform that leverages variant functionalization to link genetic variants to disease pathways, enabling the discovery and design of precision medicines. - **Other Pipeline Programs**: Several additional programs in drug discovery targeting renal, cardiovascular, and metabolic diseases. ## Market Standing - **Valuation/Market Cap**: Approximately **$1.48 Billion** (as of mid-2026, per CB Insights market cap data). - **Key Metric**: **Total Raised** (including IPO): **$496 Million**. The company also announced a **$150 Million registered offering** in 2026. - **Notable Investors/Partners**: Key investors include **Third Rock Ventures**, **Gilead Sciences**, **Genentech**, **Denali Therapeutics**, and **Calico Life Sciences** (as top talent sources and likely institutional backers). The company went public via a PIPE/IPO structure. - **Growth Signals**: - Positive topline data from the Phase 2 HORIZON trial of MZE829 (announced March 2026). - Three clinical-stage programs and several discovery-stage programs. - Active job postings increased by **120% year-over-year**. - Headcount of approximately 150 employees (based on LinkedIn data showing ~150 total employees). ## Competitive Advantages - **Proprietary Compass Platform**: A unique, data-driven platform that functionally validates genetic variants, giving Maze a differentiated ability to identify and target disease-causing pathways that are often overlooked. - **Focus on Common Diseases**: Unlike many precision medicine companies that focus on rare diseases, Maze targets large, unmet medical needs (e.g., chronic kidney disease), which represents a massive market opportunity. - **Strong Genetic Foundation**: The company’s entire strategy is built on robust human genetic evidence, reducing the risk of late-stage clinical failures and increasing the probability of success. - **Experienced Leadership Team**: The team includes veterans from leading biotech and pharma companies (Gilead, Genentech, Amgen), providing deep industry expertise in drug development and commercialization. ## Strategic Focus - **Advance Lead Programs**: Primary focus is on progressing MZE829 through Phase 2/3 trials for APOL1-mediated kidney disease and advancing MZE782 for CKD and PKU. - **Expand Pipeline**: Leveraging the Compass platform to identify and develop additional precision medicines for renal, cardiovascular, and metabolic diseases. - **Clinical Data Generation**: Delivering key clinical readouts to support regulatory filings and potential partnerships. - **Commercial Preparation**: Building the infrastructure and team (e.g., Senior Director, Talent Acquisition; Senior Director, Pharmaceutical Development) to prepare for potential late-stage success and launch. ## Why Work Here - **Mission-Driven Culture**: The company is deeply committed to "harnessing the power of genetics to transform the lives of patients," with core values of "Impact Obsessed," "Stand True" (integrity), and "Further Together" (teamwork and resilience). - **Supportive Work Environment**: Maze promotes a culture that encourages "vision, initiative, and the development of talent," with a "stimulating atmosphere where people enjoy coming to work." - **Comprehensive Benefits**: Offers "comprehensive and competitive health, financial, paid time off and many other benefits designed to promote the health and financial well-being of employees and their families." - **Equal Opportunity Employer**: Committed to diversity and non-discrimination. - **Growth Trajectory**: As a public clinical-stage company with positive clinical data and a 120% increase in job postings year-over-year, there are significant opportunities for career growth and impact. - **Location**: Based in South San Francisco (a major biotech hub), though specific remote/hybrid policy is not publicly detailed. ## Sources 1. [mazetx.com](https://mazetx.com/) 2. [mazetx.com](https://mazetx.com/about-us/) 3. [mazetx.com](https://mazetx.com/careers/) 4. [cbinsights.com](https://www.cbinsights.com/company/maze-therapeutics) 5. [linkedin.com](https://www.linkedin.com/company/mazetx) ## Other roles at Maze Therapeutics - [Senior Director, Information Technology](https://feeny.ai/job/senior-director-information-technology-maze-therapeutics-south-san-francisco-gzknm40mvm03) — South San Francisco, CA - [Manager, Chemical Development](https://feeny.ai/job/manager-chemical-development-maze-therapeutics-south-san-francisco-8x7qw5qcxd7k) — South San Francisco, CA - [Trial Master File Sr. Manager, Clinical Operations](https://feeny.ai/job/trial-master-file-sr-manager-clinical-operations-maze-therapeutics-south-san-qyae6d13b97b) — South San Francisco, CA - [Senior Project Manager, Clinical Operations](https://feeny.ai/job/senior-project-manager-clinical-operations-maze-therapeutics-south-san-francisco-tdcv9cmr2ey2) — South San Francisco, CA - [Director, Clinical Business Operations](https://feeny.ai/job/director-clinical-business-operations-maze-therapeutics-south-san-francisco-asppwh94sg0p) — South San Francisco, CA - [Oversight Director, Clinical Operations](https://feeny.ai/job/oversight-director-clinical-operations-maze-therapeutics-south-san-francisco-qxwr1q6bq364) — South San Francisco, CA - [Director, Clinical Operations](https://feeny.ai/job/director-clinical-operations-maze-therapeutics-south-san-francisco-8bfjmd3vbqe7) — South San Francisco, CA - [Senior Medical Director](https://feeny.ai/job/senior-medical-director-maze-therapeutics-south-san-francisco-p9vqa6q3dn5f) — South San Francisco, CA - [Director, Data Management](https://feeny.ai/job/director-data-management-maze-therapeutics-south-san-francisco-g2r1x3jr1v40) — South San Francisco, CA - [Director, Medical Writing](https://feeny.ai/job/director-medical-writing-lyell-immunopharma-united-states-vhfy2mbbyfy2) — United States