--- title: 'Director, Pharmacokinetics & Bioanalysis at Tarsus Pharmaceuticals' canonical: 'https://feeny.ai/job/director-pharmacokinetics-bioanalysis-tarsus-pharmaceuticals-irvine-xq1zt8han1qr' type: 'job' last_seen: '2026-10-27' --- # Director, Pharmacokinetics & Bioanalysis at Tarsus Pharmaceuticals - **Company:** Tarsus Pharmaceuticals - **Location:** Irvine, CA - **Posted:** 2026-09-22 - **Last confirmed live:** 2026-10-27 - **Apply:** https://tarsusrx.com/careers/apply/?gh_jid=6204720004 ## Job description ## About the Role As Director, Pharmacokinetics, you'll shape the scientific and strategic direction of pharmacokinetics, drug metabolism, bioanalysis, and translational PK/PD across our entire portfolio. Working at the intersection of discovery, nonclinical development, clinical development, and regulatory strategy, you'll generate the PK insights that move programs forward — and the decisions that matter most to patients. You'll design pharmacokinetic strategies tailored to each stage of development, lead internal and external activities, and partner closely with cross-functional teams to guide candidate selection, clinical dose planning, and regulatory submissions — turning scientific rigor into real progress for patients. Let’s talk about how you’ll make an impact: - Serve as Tarsus’s expert in pharmacokinetics and DMPK, shaping strategy across every program. - Architect and drive PK, DMPK, bioanalytical, and translational PK/PD strategies that carry programs from early discovery all the way through clinical development. - Design, lead, and interpret pharmacokinetic, metabolism, disposition, bioanalytical, and PK/PD nonclinical studies. - Drive human PK projections, dose and regimen selection, and interpretation of emerging clinical data. - Select and lead CROs, laboratories, consultants, and other external partners — assuring study quality, data integrity, and timelines. - Review study protocols, reports, and datasets, identify pharmacokinetic and drug-metabolism risks early, and chart the development strategies. - Author and review the pharmacokinetics, bioanalytical, and related sections of regulatory documents — including INDs, CTAs, investigator brochures, and briefing documents. - Represent Pharmacokinetics on cross-functional project teams and governance forums, translating complex science into clear, actionable recommendations leadership can act on. - Oversee the deployment, standardization, and routine execution of Phoenix WinNonlin and related modeling platforms for data analysis. Driving Innovation, Inside and Out: - Partner with our Innovation Lab and Business Development team to evaluate new assets, surfacing the risks and opportunities that shape what we pursue next. - Scout and bring in new methods, AI technologies, and external capabilities that sharpen pharmacokinetic prediction, accelerate development, and improve the quality of every program decision. - Cultivate strong scientific relationships, inside Tarsus and out, that push development forward. Factors for Success: - Decision Making - Demonstrates strong decision-making by applying structured analysis to complex challenges, balancing competing priorities and long-term impacts while engaging stakeholders and driving solutions aligned with organizational goals. - Collaboration and Team Building - Promotes collaboration by aligning diverse teams around shared goals, fostering healthy debate to advance outcomes, and building strong networks that strengthen organizational effectiveness and cross-team learning. - Outcome Driven - Demonstrates strong outcomes focus by aligning teams around shared priorities, proactively addressing risks and dependencies, and driving cross-functional accountability to sustain progress and deliver results. - Empowering Others - Fosters empowerment by aligning authority with accountability, developing leaders’ decision-making capability, and creating systems that support performance and growth. - Emotional Intelligence - Foster trust and psychological safety, navigating complex interpersonal dynamics with compassion and accountability, and adapting leadership style to support others while maintaining composure under pressure. Minimum Requirements/Qualifications: - An advanced degree in pharmacokinetics, pharmaceutical sciences, pharmacology, chemistry, biochemistry, biomedical engineering, or a related scientific field and a minimum of 10 years relevant experience; candidates with a bachelor’s or master’s degree and equivalent relevant experience (> 15 yrs) are also encouraged to apply. - Substantial industry experience in pharmacokinetics, DMPK, bioanalysis, clinical pharmacology, pharmacometrics, or a related drug-development discipline. - A track record of driving impact across drug discovery, nonclinical development, and/or clinical development programs. - Deep, broad command of pharmacokinetics, drug metabolism, bioanalysis, and how PK/PD data can sharpen development decisions. - Experience working with external research organizations, laboratories, or other development partners. - Experience preparing, reviewing, or contributing to scientific and regulatory documentation. - A gift for translating complex scientific data into clear, actionable recommendations for cross-functional teams and leaders. - Strong written, verbal, organizational, and project-management skills. - A collaborative, proactive scientist who thrives in a fast-paced, matrixed environment. - An entrepreneurial mindset and an owner’s sense of accountability. Preferred Qualifications: - Experience using Phoenix WinNonlin for modeling and simulation, including PK/PD or other quantitative approaches. - Experience supporting regulatory interactions or submissions. - Experience building scientific capabilities, mentoring the next generation of talent, or leading internal/external partnerships. A Few Other Details Worth Mentioning: - The position will be based in our beautiful Irvine office, complete with onsite gym, pool, snacks, drinks, and occasional catered meals. We provide a hybrid work environment. Remote work will be considered. - We are passionate about our culture! Our Tarsans live our values of commitment to patients, empowerment to champion innovation, and teamwork to amplify impact! - This position reports directly to the VP, Translational Science. - Some travel may be required — up to 30%. At Tarsus, we understand the importance of attracting and retaining top talent. The expected base pay range for this position is $188,200- $263,600 plus bonus, stock equity, and comprehensive benefits. The base pay range reflects the target range for this position, but individual pay will be determined by additional factors such as job-related skills, experience and relevant education or training. Our benefits include health, dental and vision insurance benefits to ensure your well-being. We believe in work-life balance and offer generous paid time off, including vacation, holidays, and personal days. For more details regarding Tarsus benefits, please visit: https://eb.alliant.com/26tarsusbenefitssnapshot. #LI-Remote Tarsus Pharmaceuticals, Inc. is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation and gender identity, national origin, disability, protected Veteran Status, or any other characteristic protected by applicable federal, state, or local law. ## About Tarsus Pharmaceuticals ## Company Overview - **One-liner**: A biopharmaceutical company creating novel therapies to treat the root cause of diseases, starting with eye care and expanding into dermatology and infectious disease prevention. - **Entity Type**: Public (NASDAQ: TARS) - **Headquarters**: Not publicly available in provided sources (inferred to be Irvine, CA, but not confirmed) - **Founded**: 2016 - **Founders**: Bobak Azamian, MD, PhD and Michael Ackermann ## Core Business - **Primary industry**: Biopharmaceuticals (eye care, dermatology, infectious disease prevention) - **Target customers**: Patients with high unmet medical needs; prescribing eye care professionals, dermatologists, and other healthcare providers (B2B/B2C hybrid) - **Mission or purpose**: To revolutionize treatment for patients with unmet needs by pursuing the root cause of disease, not just symptoms. ## Products & Services - **[XDEMVY® (lotilaner ophthalmic solution) 0.25%]**: The first and only FDA-approved treatment for Demodex blepharitis, an eyelid disease affecting approximately 25 million Americans. (Product, prescription medicine) - **[TP-03 (lotilaner ophthalmic solution)]**: Investigational treatment for Meibomian Gland Disease (MGD), currently in Phase 2a clinical trial. (Pipeline candidate) - **[TP-04]**: Investigational treatment for Rosacea (ocular rosacea), currently in Phase 2a clinical trial. (Pipeline candidate) - **[TP-05]**: Oral tablet for the prevention of Lyme disease, currently in Phase 2a clinical trial. (Pipeline candidate) ## Market Standing - **Valuation/Market Cap**: Not disclosed in provided sources (public company, stock price available via LSEG with 15-minute delay) - **Key Metric**: Annual Revenue – Not disclosed in provided sources (public company, quarterly earnings reported; Q1 2026 results mentioned but figures not included) - **Notable Investors/Partners**: Initial backing from Versant Ventures and Third Rock Ventures (per founder background); global partnerships mentioned but not specified. - **Growth Signals**: FDA approval of first product (XDEMVY); advancing three pipeline candidates into Phase 2a trials; partnership with John Cena to raise awareness of Demodex blepharitis; public listing enabling further financing. ## Competitive Advantages - **First-mover category**: XDEMVY is the only FDA-approved treatment for Demodex blepharitis, creating a new category in eye care. - **Root-cause approach**: Focus on treating the underlying cause of disease rather than symptoms, potentially offering more durable solutions. - **Expanding pipeline**: Leveraging the same platform (lotilaner) to address multiple large, underserved conditions (MGD, rosacea, Lyme disease prevention). - **Strong leadership and culture**: Experienced management team with deep biotech expertise; culture of teamwork, empowerment, and commitment. ## Strategic Focus - **Current priorities**: Commercialize XDEMVY and expand its reach; advance Phase 2a trials for TP-03, TP-04, and TP-05; pursue new categories in eye care, dermatology, and infectious disease prevention. - **Direction for growth**: Build on the success of XDEMVY to establish a pipeline of novel therapies addressing high unmet needs, with potential to expand beyond the eye. ## Why Work Here - **Culture**: Driven by core values of teamwork, empowerment, and commitment; described as nimble, differentiated, and patient-centered. - **Work model**: Hybrid work options available; on-campus gym at headquarters. - **Perks & benefits**: Comprehensive health & wellness program (medical, dental, vision with significant employer contribution), flexible time off, paid parental leave, sabbatical program, 401(k) match, Employee Stock Purchase Plan, gym reimbursement, Calm and LifeBalance memberships, cell phone allowance, in-office meals and snacks, family-building assistance via Carrot. - **Growth opportunities**: Learning and career development resources; recognition programs; exposure to a fast-growing public company with a promising pipeline. ## Sources 1. [tarsusrx.com](https://tarsusrx.com/) 2. [tarsusrx.com/careers](https://tarsusrx.com/careers/) 3. [tarsusrx.com/our-story](https://tarsusrx.com/our-story/) 4. [ir.tarsusrx.com/investor-relations](https://ir.tarsusrx.com/investor-relations) 5. 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