---
title: 'Director, Program Management at Rezo Therapeutics'
canonical: 'https://feeny.ai/job/director-program-management-rezo-therapeutics-san-francisco-c98qbx1xwr77'
type: 'job'
last_seen: '2026-10-17'
---

# Director, Program Management at Rezo Therapeutics

- **Company:** Rezo Therapeutics
- **Location:** San Francisco, CA
- **Employment:** full-time
- **Work type:** onsite
- **Posted:** 2026-10-14
- **Last confirmed live:** 2026-10-17
- **Apply:** https://jobs.lever.co/rezotx/5a99ca20-0b66-4a12-b5fc-3ec6e01f6016

## Job description

## About Rezo Therapeutics

Rezo is a different kind of biopharma company. Our mission is to dramatically increase the success rate of drug development by building a disease-agnostic, fully-integrated, network biology platform that will redefine our understanding of human disease and ability to treat it.

We are leveraging a unique integrated approach, combining capabilities in genetics, proteomics, structural biology and AI to generate deep biological insights and novel therapeutic approaches.

Located in San Francisco’s vibrant Mission Bay neighborhood, Rezo is in close proximity to UCSF, numerous urban amenities, and outdoor recreational opportunities. We recognize that realizing our mission depends as much on our people as it does on our science and are building a workplace that fosters collaboration, respect, and diversity where contributing to your team’s success is valued as highly as individual achievements.  If you’re passionate about team science and breaking down barriers to progress in drug development, please consider joining us!

The Opportunity We are seeking an experienced and highly organized Director of Program Management to join the R&D organization. This individual will play a key leadership role in scaling and advancing Rezo’s Program Management capabilities as the company enters its next stage of growth.

What You'll Do:

- Provide effective leadership and direction to translate company goals into plans of action with measurable deliverables
- Partner with PTLs in project/program team working group meetings to translate project/program strategy and stakeholder management into efficient execution plans
- Lead cross-functional team meetings for advanced programs to drive program strategy, key decision-making, and risk assessments (scheduling, timelines, costs, etc.)
- Create master program timelines and project/program plans to ensure efficient initiation and completion of activities
- Oversee the research and communication with external collaborations, including SRAs, industry partners, and CROs, ensuring alignment to accomplish the goals of each collaboration
- As the Rezo pipeline advances, build a high-performing PM team to manage cross functional efforts and direct our therapeutic programs through IND submission and into the clinic
- Continue to evolve and implement consistent best practices in program management across the organization with clear continuity between functions, especially in the IND-enabling space (Platform, Discovery, CMC, Clinical, Regulatory, BD, etc.)
- Collaborate with executive leadership to develop, implement, and ensure adherence to company-wide operational procedures and process improvements (documentation policies, data and file storage organization, presentation materials, etc.)

About You:

- BS, MS, or PhD (advanced degree preferred) in the Life Sciences, with previous experience as a bench scientist preferred
- Typically, a minimum of 10+ years of related work experience in Biotech or Pharma with a BS (8+ years with an advanced degree), with prior experience at a startup highly desirable
- Formally educated, trained, and/or certified in Project/Program Management (PMP, CAPM, etc.)
- Successful track record in managing complex projects/programs and other business activities within a matrixed environment of diverse stakeholders
- Previous experience as PM for IND-enabling studies and document preparation is preferred
- Adept at using interpersonal and communication skills, as well as influence, to ensure optimal team performance and completion of deliverables
- Well-versed in commonly used professional project/program management platforms/software, including Smartsheet and Office Timeline (or other timeline visualization tools)

## Compensation at Rezo

The expected starting salary range for this position based in San Francisco, California for Director level is $160,000-$240,000. Actual starting salary will be determined based on multiple job-related factors including candidate’s skills, education, and experience, the level at which they are hired, market demand, business needs, and internal parity. This role is eligible for participation in our Annual Discretionary Bonus Plan (based on individual and company performance) and our Equity Incentive Plan, subject to the terms of those plans and associated policies. This position is also eligible for the benefits detailed below.

## Benefits at Rezo

Medical (HMO or PPO), dental, and vision insurance Discretionary time off policy Company holidays (including summer and winter shutdown) 401(k) retirement savings program Commuter / Mass Transit Benefit Program Healthcare Flexible Spending Account (FSA) Dependent care Flexible Spending Account (FSA) Parental leave Competitive compensation Flexible work schedule

## EEOC

At Rezo we value a diverse, equitable, inclusive workplace and provide equal employment opportunity to all persons without regard to race, color, sex, gender identity, gender expression, religion, age, national origin, ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws.  This statement covers all facets of employment and is especially important when it comes to growing our team.

If you are wondering if you’ll belong at Rezo, or are worried that you don’t meet 100% of the qualifications for this role, take a chance on us and yourself — please apply!

SF Fair Chance Ordinance Pursuant to the San Francisco Fair Chance Ordinance, Rezo considers qualified applicants with arrest and conviction records for employment.

## About Rezo Therapeutics

## Company Overview
- **One-liner**: Rezo Therapeutics is a biopharmaceutical company leveraging an integrated network biology platform to map molecular disease networks and discover precision therapeutics, initially focused on oncology.
- **Entity Type**: Private (Series A, $78M total funding)
- **Headquarters**: San Francisco, California, United States (455 Mission Bay Blvd South, San Francisco, CA 94158)
- **Founded**: 2021 (first funding round date)
- **Founders**: Nevan Krogan, Ph.D. (UCSF/QBI), Kevan Shokat, Ph.D. (UCSF), Sourav Bandyopadhyay, Ph.D. (UCSF), Natalia Jura, Ph.D. (UCSF) – along with board members George Scangos and Norbert Bischofberger.

## Core Business
- **Primary industry**: Biotechnology Research / Biopharmaceuticals (drug discovery and development)
- **Target customers**: B2B/Enterprise (pharma partnerships) and ultimately patients (therapeutics)
- **Mission**: “To dramatically increase the success rate of drug development by building a disease-agnostic, fully-integrated, network biology platform that will redefine our understanding of human disease and ability to treat it.” [rezotx.com](https://rezotx.com/)

## Products & Services
- **Network Biology Platform**: A proprietary, integrated platform combining proteomics, genetics, structural biology, chemistry, and bioinformatics to create comprehensive maps of molecular disease networks. This platform is used to identify novel, druggable targets for precision therapeutics. [rezotx.com](https://rezotx.com/)
- **Therapeutic Pipeline**: Preclinical programs in oncology (no specific drug candidates publicly disclosed). The company is disease-agnostic but currently focused on oncology.

## Market Standing
- **Valuation/Market Cap**: Not publicly disclosed
- **Key Metric**: Total Funding – $78M (Series A, closed November 2022)
- **Notable Investors/Partners**: Norwest Venture Partners, SR One (lead investors in Series A), plus 7 other undisclosed investors. [linkedin.com](https://linkedin.com/company/rezotx)
- **Growth Signals**:
  - Headcount growth of +4.8% YoY (26 employees as of mid-2025) [linkedin.com](https://linkedin.com/company/rezotx)
  - Appointed Derek Hicks as CEO in August 2025 (former Chief Business Officer at Intellia Therapeutics) [linkedin.com](https://linkedin.com/company/rezotx)
  - Appointed Cristiana Guiducci, Ph.D., as Chief Scientific Officer in July 2024 (former SVP at Nurix Therapeutics) [linkedin.com](https://linkedin.com/company/rezotx)
  - Named to BioSpace’s “Most Promising New Biopharma Companies to Watch in 2024” [linkedin.com](https://linkedin.com/company/rezotx)
  - Active job postings increased 50% month-over-month (3 open roles) [linkedin.com](https://linkedin.com/company/rezotx)

## Competitive Advantages
- **Network biology approach**: Integrates proteomics, genetics, and AI to map disease networks holistically, potentially identifying targets missed by traditional methods.
- **World-class academic founders**: Co-founders are leading scientists from UCSF (Krogan, Shokat, Bandyopadhyay, Jura) with deep expertise in molecular biology and drug discovery.
- **Experienced leadership**: CEO Derek Hicks has extensive biotech business development experience (Intellia, Spark, Pfizer); CSO Cristiana Guiducci brings 19+ years in oncology and immunology drug discovery.
- **Strong investor backing**: $78M from top-tier healthcare investors (Norwest, SR One).

## Strategic Focus
- **Current priorities**: Advancing the network biology platform and building a pipeline of precision therapeutics in oncology. The company is actively hiring for senior scientific roles (medicinal chemistry, in vivo pharmacology, bioinformatics data science) to accelerate R&D. [rezotx.com/careers](https://rezotx.com/careers/)
- **Growth direction**: Scaling the platform to additional disease areas, expanding the team, and progressing toward clinical development.

## Why Work Here
- **Mission-driven**: Opportunity to work on cutting-edge drug discovery that could significantly improve success rates in developing new therapies.
- **Research-focused culture**: Emphasis on deep science, collaboration, and innovation. The team includes experts from UCSF, Google, Merck, and other top institutions. [linkedin.com](https://linkedin.com/company/rezotx)
- **Work environment**: Full-time onsite in South San Francisco (Mission Bay). Roles are primarily scientific (medicinal chemistry, pharmacology, bioinformatics). [rezotx.com/careers](https://rezotx.com/careers/)
- **Growth trajectory**: Young company with strong funding and recent executive hires, offering potential for career advancement as the organization scales.
- **Notable perks**: Not explicitly disclosed, but typical for early-stage biotech: equity, comprehensive benefits, and the chance to be part of a high-impact team.

## Sources
1. [Rezo Therapeutics Website](https://rezotx.com/)
2. [Rezo Careers Page (Lever)](https://jobs.lever.co/rezotx)
3. [Rezo LinkedIn Company Profile](https://linkedin.com/company/rezotx)
4. [Rezo Team Page](https://rezotx.com/team/)

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