---
title: 'Director, Revenue Accounting at Xenon Pharmaceuticals'
canonical: 'https://feeny.ai/job/director-revenue-accounting-xenon-pharmaceuticals-boston-mrgfjws863a7'
type: 'job'
last_seen: '2026-09-10'
---

# Director, Revenue Accounting at Xenon Pharmaceuticals

- **Company:** Xenon Pharmaceuticals
- **Location:** Boston, MA
- **Employment:** full-time
- **Work type:** onsite
- **Posted:** 2026-08-19
- **Last confirmed live:** 2026-09-10
- **Apply:** https://jobs.ashbyhq.com/xenon/02273d33-05dc-4346-9543-2b312d8a48be

## Job description

Who We Are: Xenon Pharmaceuticals ([NASDAQ:XENE](https://www.nasdaq.com/market-activity/stocks/xene)) is a neuroscience-focused biopharmaceutical company dedicated to drug discovery, clinical development, and commercialization of life-changing therapeutics for patients in need. We are looking for great people who thrive in a respectful, collaborative, inclusive, and productive culture to join the Xenon team. What We Do: We are advancing an [exciting product pipeline](https://xenon-pharma.com/pipeline) to address indications with high unmet medical need, including epilepsy, depression and pain. Our Phase 3 azetukalner program represents the most advanced, clinically validated potassium channel modulator in late-stage clinical development for multiple indications. In March 2026, we announced positive topline data from our Phase 3 X-TOLE2 study of azetukalner in focal onset seizures (FOS), and we anticipate submitting a New Drug Application to the Food and Drug Administration in the third quarter of 2026. Our Phase 3 epilepsy program also includes a second FOS study, X-TOLE3, which would support regulatory submissions outside the U.S., and the X-ACKT study in primary generalized tonic-clonic seizures, which would support regulatory submissions for an additional epilepsy indication. We also have multiple Phase 3 azetukalner clinical trials underway in major depressive disorder (MDD) and bipolar depression (BPD), based on topline data from our Phase 2 X-NOVA clinical trial. In addition, we are proud of our strong heritage in human genetics, deep understanding of ion channel biology, and expertise in novel chemistries to enable potent, selective ion channel targeting. We continue to advance an early-stage pipeline of novel therapeutic candidates, including Phase 1 studies for XEN1701 and XEN1720 (targeting Nav1.7) and XEN1120 (targeting Kv7), which are being developed for pain. Backed by a strong balance sheet to support our growth plans, we continue to build a fully integrated, premier neuroscience company with strong discovery, clinical development, corporate, and commercial operations. About the Role: We are seeking a Director, Revenue Accounting to join our team. This role will be a key member of the Finance department and will play a crucial role for revenue recognition and Gross‑to‑Net (GTN) accounting under ASC 606, while collaborating with key stakeholders in the Commercial organization. The Director will establish scalable commercial accounting infrastructure, oversee pricing and top‑line analytics, support revenue guidance, and ensure SOX‑compliant controls as Xenon transitions from an R&D‑centric to a commercial‑centric company. This role partners cross‑functionally to deliver accurate revenue reporting, robust forecasting, and clear executive‑level insights into business performance and value drivers. This role reports to the VP, Finance and is based out of Boston, MA, USA, in our Needham office. The level of the position will be commensurate with the candidate’s education and industry experience. Hybrid positions require a minimum of two onsite days per week.

## RESPONSIBILITIES:

- Design, implement, and maintain GTN reserve methodologies, including documentation of reasonable assumptions: commercial and government rebates, chargebacks, copay and patient assistance programs, distribution service fees, returns and other variable considerations
- Responsible for monthly close processes for revenue and GTN, including journal entries, account reconciliations, true‑ups, and variance analysis
- Manage the quarterly GTN forecasting process by ensuring alignment between Commercial revenue forecast and guidance and report against such guidance, including analysis of pricing actions, margin dynamics, and market trends
- Manage government pricing reporting and state price transparency reporting with internal stakeholders and outsourced vendor(s), and ensure appropriate compliance with regulatory requirements
- Work within finance systems to implement or enhance systems to address planning and reporting needs of commercial accounting and GTN processes
- Establish and maintain scalable data flows with 3PLs and other parties; review data provided by external parties for completeness, accuracy, and reasonable
- Build SOX‑compliant internal controls, policies, and SOPs in preparation for commercial launch and first audit cycles.
- Serve as the primary commercial accounting contact for external auditors
- Prepare analysis, commentary, and presentation materials for monthly and quarterly financial reviews, including executive leadership and Board of Directors meetings
- Partner with Commercial team on pricing strategy and other strategic analysis as required
- Develop and propose short- and long-term objectives for the function in accordance with overall Company strategies and plans
- Act in accordance with Company policies, including, for example, the Code of Business Conduct and Ethics and ensure policies are understood and followed by direct reports
- Other duties as assigned

## QUALIFICATIONS:

- Professional designation (CPA or equivalent) is required, technical training with Big Four CPA firm or large regional CPA firm preferred
- 10+ years of progressive finance and/or accounting experience with significant biotech or pharmaceutical commercial exposure
- Demonstrated experience supporting at least one successful first commercial product launch and experience with designing commercial accounting processes under US GAAP and SOX environment
- Strong expertise in Gross-to-Net accounting, revenue recognition, and government pricing
- Strong knowledge of U.S. pharmaceutical distribution models, including specialty pharmacy, specialty distributor, 3PL, PBMs, GPOs, patient support programs, and 340B
- Experience in ERP implementations or financial systems transformation initiatives; experience with Oracle Fusion and Adaptive Planning is a bonus
- Proven experience building strong relationships with internal stakeholders and external service providers
- Excellent organizational skills and the ability to manage concurrent deliverables and work effectively in a challenging, high performance, team environment
- Exceptional interpersonal and communication skills (written and oral); communicates in a clear, concise and organized manner; listens and works collaboratively with others outside of Finance to obtain information
- Able to think and act strategically, anticipate road-blocks and map out next steps in support of a fast-growing company
- Self-motivated, with initiative and the ability to take ownership of, and drive projects from start to finish
- Demonstrated high level of integrity and ethics

Our Total Rewards program includes base salary, target bonus, and stock options, as well as a full range of benefits including medical, dental, vision, short-& long-term disability, accidental death & dismemberment, and life insurance programs, Employee Assistance Program, travel insurance, and retirement savings programs with company matching contributions. Xenon encourages time to rest and re-charge through vacation, personal days, sick days, and an end-of-year company shutdown. Xenon highly values employee development and has an expanding Training, Learning & Development program, including a Tuition Assistance program for advanced degrees.

## About Xenon Pharmaceuticals

## Company Overview
- **One-liner**: Xenon Pharmaceuticals is a neuroscience-focused biopharmaceutical company dedicated to discovering, developing, and commercializing life-changing therapeutics for people living with neurological and psychiatric disorders.
- **Entity Type**: Public (Ticker: XENE on Nasdaq)
- **Headquarters**: Burnaby, British Columbia, Canada
- **Founded**: 1996
- **Founders**: Not publicly listed as individual founders; the company was founded based on a platform science capable of discovering new genetic targets to treat human disease.

## Core Business
- **Primary industry/industries**: Biotechnology, Neuroscience, Pharmaceuticals
- **Target customers**: Patients with neurological and psychiatric disorders (epilepsy, major depressive disorder, bipolar depression, pain); healthcare providers; payers.
- **Mission or purpose statement**: "To deliver innovative medicines that provide a brighter future for people living with neurological and psychiatric disorders." [xenon-pharma.com](https://xenon-pharma.com/about)

## Products & Services
Xenon’s pipeline is focused on ion channel science, specifically potassium (KV7) and sodium (NaV) channel modulators.

- **Azetukalner (KV7 Potassium Channel Opener)**: The lead late-stage investigational candidate. It is in multiple Phase 3 clinical trials for:
    - Focal onset seizures (Phase 3 X-TOLE2 completed, X-TOLE3 ongoing)
    - Primary generalized tonic-clonic seizures (Phase 3 X-ACKT)
    - Major depressive disorder (Phase 3 X-NOVA2 and X-NOVA3)
    - Bipolar depression (Phase 3 X-CEED)
- **XEN1120 (KV7 Potassium Channel Opener)**: An early-stage (Phase 1) candidate for the treatment of pain.
- **XEN1701 (NaV1.7 Sodium Channel Inhibitor)**: An early-stage (Phase 1) candidate for the treatment of pain.
- **NBI-921355 (Partnered with Neurocrine Biosciences)**: A NaV1.2/1.6 inhibitor in development for epilepsy, pain, and psychiatry. [xenon-pharma.com](https://xenon-pharma.com/pipeline)

## Market Standing
- **Valuation/Market Cap**: Not publicly available in the provided search results. As a public company, this fluctuates daily.
- **Key Metric**: Annual Revenue of $7.5M (as per LinkedIn). As a clinical-stage biotech, the primary focus is on pipeline progress and cash runway rather than revenue.
- **Notable Investors/Partners**: Neurocrine Biosciences (partner for NBI-921355). The company has also had strategic partnerships with multiple premier biopharmaceutical companies focused on pain, metabolic, and cardiovascular disease. [xenon-pharma.com](https://xenon-pharma.com/about)
- **Growth Signals**: The company is in a significant growth phase, having initiated multiple Phase 3 clinical trials for its lead candidate, azetukalner, across epilepsy, major depressive disorder, and bipolar depression. This represents a major expansion of its clinical pipeline and a transition towards a late-stage, fully integrated biopharmaceutical company. [xenon-pharma.com](https://xenon-pharma.com/about)

## Competitive Advantages
- **Deep Expertise in Ion Channel Biology**: Xenon is one of the scientific leaders in ion channel drug discovery, with a specific focus on potassium (KV7) and sodium (NaV) channel modulators. This is a highly specialized and technically difficult area of drug development. [xenon-pharma.com](https://xenon-pharma.com/about)
- **Proprietary Pipeline**: The company has a wholly-owned, late-stage pipeline led by azetukalner, a novel KV7 potassium channel opener being studied across multiple high-need indications (epilepsy, MDD, bipolar depression). This provides significant potential upside and control over its future.
- **Strong Scientific Foundation**: Founded on a platform capable of discovering new genetic targets, the company has a deep history of translating genetic insights into novel therapeutic candidates. [xenon-pharma.com](https://xenon-pharma.com/about)
- **Strategic Partnerships**: A history of partnerships with premier biopharmaceutical companies (e.g., Neurocrine Biosciences) validates its platform and provides non-dilutive funding. [xenon-pharma.com](https://xenon-pharma.com/about)

## Strategic Focus
- **Advancing Late-Stage Pipeline**: The primary focus is on executing the Phase 3 clinical programs for azetukalner across epilepsy, major depressive disorder, and bipolar depression, with the goal of regulatory approval and commercialization.
- **Expanding Early-Stage Pipeline**: Continuing to advance early-stage candidates (XEN1120, XEN1701) for pain and other high-need indications.
- **Building a Fully Integrated Company**: Transitioning from a discovery and development company to one with commercial capabilities, as evidenced by the hiring of a Chief Commercial Officer. [xenon-pharma.com](https://xenon-pharma.com/about)
- **Deepening Ion Channel Leadership**: Maintaining its position as a scientific leader in ion channel drug discovery, with a deep focus on potassium (KV7) and sodium (NaV) channel modulators. [xenon-pharma.com](https://xenon-pharma.com/about)

## Why Work Here
- **Mission-Driven Work**: Employees are united by a clear and compelling mission to deliver innovative medicines for patients with neurological and psychiatric disorders who have been underserved for too long. [xenon-pharma.com](https://xenon-pharma.com/about)
- **Culture of Collaboration and Impact**: The company describes itself as collaborative, ambitious, resilient, ethical, and science-driven. The culture is shaped by the "XenonCARES" program, which focuses on professional growth, wellness, and community. [xenon-pharma.com](https://xenon-pharma.com/join-us)
- **Competitive Compensation & Benefits**: Offers a total compensation package including base salary, performance-based bonuses, and equity. Benefits include comprehensive medical, dental, and vision coverage (US and Canada), a retirement savings program with a generous employer match, and a tuition reimbursement program. [xenon-pharma.com](https://xenon-pharma.com/join-us)
- **Work Flexibility**: The company values flexibility and provides a stipend for work-from-home setups. They also offer generous paid vacation time and an annual holiday shutdown. [xenon-pharma.com](https://xenon-pharma.com/join-us)
- **Growth & Development**: Recognizes and supports team member growth through leadership and development opportunities, a tuition reimbursement program, and recognition programs for both big and small wins. [xenon-pharma.com](https://xenon-pharma.com/join-us)
- **Work Model**: Hybrid/Remote-friendly with a stipend for home office setups. Offices are located in Burnaby, British Columbia (HQ) and the United States. [xenon-pharma.com](https://xenon-pharma.com/join-us)
- **Diversity & Inclusion**: The company states it cultivates and celebrates diversity, viewing diverse backgrounds, experiences, and opinions as a great asset, and is committed to fostering a safe and inclusive environment. [xenon-pharma.com](https://xenon-pharma.com/join-us)

## Sources
1. [xenon-pharma.com](https://xenon-pharma.com/)
2. [xenon-pharma.com](https://xenon-pharma.com/about)
3. [xenon-pharma.com](https://xenon-pharma.com/join-us)
4. [xenon-pharma.com](https://xenon-pharma.com/pipeline)
5. [linkedin.com](https://www.linkedin.com/company/xenonpharma)

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