---
title: 'Director/Senior Director, In Vitro Biology & Molecular Pharmacology at Schrödinger'
canonical: 'https://feeny.ai/job/director-senior-director-in-vitro-biology-molecular-pharmacology-schrodinger-s5cyb910awa0'
type: 'job'
last_seen: '2026-09-16'
---

# Director/Senior Director, In Vitro Biology & Molecular Pharmacology at Schrödinger

- **Company:** Schrödinger
- **Location:** Framingham, MA / New York, NY
- **Posted:** 2026-08-27
- **Last confirmed live:** 2026-09-16
- **Apply:** https://job-boards.greenhouse.io/schrdinger/jobs/7822234003

## Job description

We’re seeking a Director/Senior Director of In Vitro Biology and Molecular Pharmacology to join us in our mission to transform the discovery of novel therapeutics.

Schrödinger has pioneered a physics-based software platform that enables discovery of high-quality, novel molecules for drug development and materials applications more rapidly and at lower cost compared to traditional methods. The software platform is used by biopharmaceutical and industrial companies, academic institutions, and government laboratories around the world. Our multidisciplinary drug discovery team also leverages the software platform to advance collaborative programs and its own pipeline of novel therapeutics to address unmet medical needs.

As a senior member of our Therapeutics Group, you’ll direct strategy and execution across a pipeline of small molecule drug discovery programs, with a particular focus on undrugged targets, novel modalities, and novel hit finding approaches. By setting the vision for IVB/MP capabilities, driving pipeline-level decisions, and managing a high-performing team, you will shape pipeline and program strategy while maintaining scientific depth.

Who will love this job:

- An experienced drug hunter with hands-on experience across several hit finding modalities, including DEL, fragment screening, HTS/MTS, and chemoproteomics
- A seasoned in vitro biologist and molecular pharmacologist with a track record of developing assays and prosecuting programs against difficult-to-drug targets
- A portfolio-level thinker with a broad strategic view who enjoys remaining scientifically close to individual programs
- A leader with a passion for managing cross-disciplinary teams and developing talent
- An excellent scientific communicator who is comfortable presenting and defending innovative strategies to senior leadership

What you’ll do:

- Set the strategic direction for In Vitro Biology across the Therapeutics Group portfolio, and represent the function on governance bodies covering portfolio prioritization, resource allocation, and Go/No-Go decisions
- Assess target tractability and risk during target selection, and define the assay cascade needed to advance a target from hit identification through Development Candidate selection
- Spearhead the organization wide hit finding strategy, collaborating across functions to design and execute screening campaigns across DEL, fragment-based, HTS/MTS, and chemoproteomic platforms, focusing on novel methods for undrugged targets
- Provide scientific oversight across multiple programs, including challenging target classes such as protein–protein interactions, undrugged targets, and degrader programs
- Tackle complex in vitro biology and molecular pharmacology challenges including resolving difficult challenges like biochemical-to-cellular disconnects and in vitro to in vivo translatability
- Act as the IVB project lead when needed, guiding timelines and strategy in close partnership with medicinal chemistry, computational chemistry and structural biology leads
- Lead and develop the In Vitro Biology and Molecular Pharmacology team, mentoring direct reports and building a culture of scientific rigor and collaboration
- Own the CRO strategy for In Vitro Biology, including partner selection, budget and FTE planning, quarterly reviews, KPI accountability, and remediation of performance issues
- Identify capability gaps and drive investment in new technologies and platforms, and feed practical, assay-driven requirements back into Schrödinger's platform and data infrastructure

What you should have:

- PhD in Biochemistry, Molecular Pharmacology, Chemical Biology, Cell Biology or a related discipline
- At least ten years of industry experience in drug discovery, including leadership experience
- Experience leading in vitro biology teams and managing direct reports
- Demonstrated background with developing assays and prosecuting programs against undrugged targets
- Significant experience across multiple hit finding modalities (DEL, fragment screening, HTS/MTS, chemoproteomics) and a track record of advancing hits for challenging target classes
- Deep expertise in biochemical, biophysical, and cell-based assay design
- Strong experience managing strategic CRO partnerships, including governance, budgets and FTE planning

We’d prefer to hire someone with:

- Understanding of protein degrader biology (PROTACs, molecular glues) and associated assay formats
- Familiarity with data platforms such as LiveDesign
- Experience contributing to organizational strategy and governance committees
- Experience designing and interpreting in vivo PK/PD and efficacy studies

Pay and perks:

Schrödinger understands it’s people that make a company great. Because of this, we’re prepared to offer a competitive salary, stock options, and a wide range of benefits that include healthcare (with dental and vision), a 401k, pre-tax commuter benefits, a flexible work schedule, and a parental leave program. We have a company culture that is relaxed but engaged, and over a month of paid vacation time. New York is home to our largest office, but we have teams all over the world. Schrödinger is honored to have been selected as one of Crain's New York Best Places to Work for the past three years running.

Estimated base salary range: $195,000 - $300,000. Actual compensation package is dependent on a number of factors, including, for example, experience, education, degrees held, market data, and business needs. If you have any questions regarding the compensation for this role, do not hesitate to reach out to a member of our Strategic Growth team.

Sound exciting? Apply today and join us!

As an equal opportunity employer, Schrödinger hires outstanding individuals into every position in the company. People who work with us have a high degree of engagement, a commitment to working effectively in teams, and a passion for the company's mission. We place the highest value on creating a safe environment where our employees can grow and contribute, and refuse to discriminate on the basis of race, color, religious belief, sex, age, disability, national origin, alienage or citizenship status, marital status, partnership status, caregiver status, sexual and reproductive health decisions, gender identity or expression, sexual orientation, or any other protected characteristic. To us, "diversity" isn't just a buzzword, but an important element of our core principles and key business practices. We believe that diverse companies innovate better and think more creatively than homogenous ones because they take into account a wide range of viewpoints. For us, greater diversity doesn't mean better headlines or public images - it means increased adaptability and profitability.

## About Schrödinger

## Company Overview
- **One-liner**: Schrödinger provides a physics-based computational platform for molecular discovery and design, transforming how therapeutics and materials are discovered.
- **Entity Type**: Public (Nasdaq: SDGR)
- **Headquarters**: New York, New York, USA
- **Founded**: 1990
- **Founders**: Dr. Richard A. Friesner (co-founder) and Dr. William A. Goddard III (co-founder)

## Core Business
- **Primary industry/industries**: Biotechnology, Drug Discovery, Materials Science, Computational Chemistry, Software
- **Target customers**: B2B — pharmaceutical companies, biotech firms, and materials science organizations (R&D, discovery teams); also serves academic institutions.
- **Mission or purpose statement**: “Our mission is to improve human health and quality of life by transforming the way therapeutics and materials are discovered.” [schrodinger.com](https://www.schrodinger.com/company/about/)

## Products & Services
- **FEP+ (Free Energy Perturbation+)**: A physics-based computational tool for accurately predicting binding affinities and optimizing drug candidates (SaaS).
- **LiveDesign**: An enterprise platform for collaborative molecular design, enabling teams to track, analyze, and share data in real time (SaaS).
- **Schrödinger Platform (Core)**: A comprehensive suite of physics-based modeling and simulation tools for small molecule discovery, materials design, and predictive modeling (SaaS).
- **Materials Science Platform**: Specialized tools for designing polymers, formulations, and advanced materials (SaaS).
- **Drug Discovery Pipeline**: Internal and collaborative drug discovery programs targeting high-value therapeutic areas, leveraging their own platform.
- **Education & Certification**: Online courses and certification programs for computational chemistry and molecular design.

## Market Standing
- **Valuation/Market Cap**: As of early 2025, market cap is approximately $2.5–3.0 billion (fluctuates with market).
- **Key Metric**: Annual Revenue (public) — FY2024 revenue was approximately $180–200 million (SaaS + drug discovery collaborations).
- **Notable Investors/Partners**: Key partners include major pharmaceutical companies (e.g., Novartis, Takeda, Bayer) and materials science firms. Public shareholders include institutional investors like Vanguard and BlackRock.
- **Growth Signals**: Consistently growing software revenue; expanding drug discovery pipeline; recognized as a leader in computational chemistry; listed on the 2022 *Fortune* 100 Fastest-Growing Companies; named #1 in Pharmaceuticals and Biotech on *Newsweek*’s America’s 100 Most Loved Workplaces 2022. [schrodinger.com](https://www.schrodinger.com/company/about/)

## Competitive Advantages
- **Physics-based platform**: Proprietary, physics-first approach (not purely AI/ML) that provides high accuracy and predictive power, differentiating from competitors.
- **Deep R&D investment**: Over 30 years of continuous investment in computational methods and force fields.
- **Integrated platform + pipeline**: The company uses its own platform internally to advance a pipeline of drug discovery programs, creating a virtuous feedback loop for platform improvement.
- **Strong IP moat**: Extensive patent portfolio covering both the platform and drug discovery methods.
- **Established partnerships**: Long-term collaborations with top pharma and materials companies, providing recurring revenue and validation.

## Strategic Focus
- **Platform expansion**: Continuing to enhance the physics-based platform with machine learning and AI capabilities (e.g., ML-driven force fields, retrosynthesis).
- **Therapeutics pipeline**: Advancing proprietary and collaborative drug programs into the clinic, focusing on high-value targets with human genetics validation.
- **Materials science growth**: Expanding the materials platform into new industries (e.g., electronics, consumer goods).
- **Global reach**: Growing operations in key markets including Japan, India, and Europe.

## Why Work Here
- **Culture & values**: Emphasizes collaboration, compassion, diversity, and ethical conduct. Recognized as a top workplace (No. 1 in Pharmaceuticals and Biotech on *Newsweek*’s 100 Most Loved Workplaces 2022). [schrodinger.com](https://www.schrodinger.com/company/about/)
- **Work environment**: Flexible work environment with hybrid options. New York office features snack options, gym access, and modern collaborative spaces. [schrodinger.com](https://www.schrodinger.com/company/careers/)
- **Benefits**: Competitive salary and annual bonuses; equity compensation; 401k with employer match; over a month of paid vacation; two annual company shut-down weeks; paid parental leave; subsidized backup care (child/elder/pet); medical, dental, vision; mental health benefits; flexible spending accounts; tuition reimbursement; access to Schrödinger’s online courses and mentor program. [schrodinger.com](https://www.schrodinger.com/company/careers/)
- **Engineering & science culture**: A multidisciplinary team of over 800 employees (scientists, software engineers, ML engineers) working at the intersection of physics, chemistry, and computer science. Strong focus on professional development and learning.
- **Global presence**: 12 offices worldwide (New York, Cambridge, San Diego, Portland, Hyderabad, Tokyo, Munich, Mannheim, London, and more), offering a diverse, global team.

## Sources
1. [Schrödinger About Page](https://www.schrodinger.com/company/about/)
2. [Schrödinger Careers Page](https://www.schrodinger.com/company/careers/)
3. [Schrödinger Homepage](https://www.schrodinger.com/)
4. [Schrödinger Team Page](https://www.schrodinger.com/company/team/)
5. [Schrödinger Jobs on Greenhouse](http://job-boards.greenhouse.io/schrdinger)

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