---
title: 'Director, Site Engagement & Monitoring Excellence (CONTRACT) at Eikon Therapeutics'
canonical: 'https://feeny.ai/job/director-site-engagement-monitoring-excellence-contract-eikon-therapeutics-mq2a3tcremrq'
type: 'job'
last_seen: '2026-11-08'
---

# Director, Site Engagement & Monitoring Excellence (CONTRACT) at Eikon Therapeutics

- **Company:** Eikon Therapeutics
- **Location:** Jersey City, NJ / Millbrae, CA
- **Posted:** 2026-11-02
- **Last confirmed live:** 2026-11-08
- **Apply:** https://job-boards.greenhouse.io/eikontherapeutics/jobs/5280255007

## Job description

Eikon Therapeutics is a new biopharmaceutical company employing revolutionary technology at the intersection of chemistry, engineering, computation, and biology to discover novel treatments for life-threatening diseases. Eikon’s discovery platform is built on groundbreaking innovations from its founders (Nobel Prize, 2014), culminating in the creation of microscopes which enable real time, molecular-resolution measurements of protein movement in living cells, thereby unlocking otherwise intractable classes of proteins as drug targets.

Position

The Director Study Site Engagement & Monitoring Excellence (CONTRACT) will be responsible for leading the development and execution of Eikon’s global trial site engagement strategy, including oversight and accountability for all internal/external managed site monitoring activities to ensure predictable delivery of high-quality data and establish Eikon as a preferred sponsor for clinical sites.

The Director will ensure effective collaboration with clinical study teams, and Functional Service Provider (FSP) partners, to implement excellent site relationship management and site monitoring activities to accelerate operational excellent delivery of Eikon’s clinical programs.

This role will require a minimum of 3 days a week of onsite presence (or more as business needs require) in either of our California or New Jersey offices to ensure effective management, operational excellence and high-performance delivery of clinical studies and to support the expected significant team growth & collaboration.

## What You’ll Do

Strategic Leadership

- Define and implement site engagement strategies to improve relationships
- Support the build of new partnerships and networks
- Support high quality monitoring approaches and ensure alignment with regulatory standards
- Serve as liaison between clinical study teams and investigative sites

Operational Support

- Provide guidance, oversight and training to the study site engagement team, including CRA site monitors, whether insourced or outsourced suppliers, to maximize effectiveness and acceleration in Eikon’s operational execution of clinical research.
- Develop and maintain appropriate performance standards, processes and documentation for harmonized site engagement and monitoring support across Eikon’s clinical programs.
- Maintain regular information exchange within the study site engagement team, identify common elements of study support across regions/countries to codify and apply lessons learned, troubleshoot issues and distribute acquired site intelligence to Clinical Operations study teams and Clinical Development stakeholders as required.
- Oversee resource and talent management of site engagement team, including CRA monitors, whether insourced or via outsourced suppliers, across relevant regional/country clusters to maintain quality of monitoring that deliver and achieve Clinical Operations study team goals.
- Accountable for overall oversight and training of FSP, study site engagement and CRAs by country/region, including identifying and managing CRA performance issues. Responsible for ensuring associated corrective and preventative actions are put in place, and that ICH GCP compliance, regulatory, quality and timeline objectives are met for all trials executed globally.
- Responsible for site and monitoring quality using interpretive signals in conjunction with local country intelligence to proactively identify risks.  Lead risk assessment at the site/country level for designated studies, including identification of mitigation and control.  Maintain knowledge of appropriate tools and resources (e.g., metrics, site health, Risk Based Monitoring signals, etc.) and demonstrate use of data to enhance quality and accelerate study delivery. Track site engagement metrics and satisfaction scores.
- Demonstrate a learning culture by ensuring site quality and trends, including preventative actions are shared across study & assets in the clinical programs to drive accelerated drug delivery.
- Be the point of escalation for issues that arise in site engagement, escalating as necessary and keeping the relevant Clinical Operations study team informed of escalation and resolution. Effectively solve problems and use judgment relating to national and international regulations, guidelines, investigator interactions and timelines.
- Manage functional budget, including resource projections, capacity assessment and vendor (e.g., FSP) oversight and evaluation, to ensure adequate and appropriate resourcing for Eikon’s clinical trial portfolio.

Cross Functional Collaboration

- Align with global Clinical Development stakeholders to ensure strategy and approach for clinical programs and studies is appropriate to meet study goals while incorporating study engagement team, including CRA monitors.
- Contribute to ongoing department infrastructure development efforts such as SOP development, implementation and/or innovation of new processes and clinical system capabilities to consistently deliver operational excellence.
- Collaborate with Clinical Development leadership to partner on important projects and stay current with relevant industry trends and innovations to ensure best practices in study site engagement are applied across Eikon.
- Serve as a talent magnet and develop, coach, and retain top talent in the team. Set clear performance standards and holds self and organization accountable for achieving results. Embraces metrics and performance standards (KPIs).

## Qualifications

- Post Graduate degree with 10+ years of experience or a Bachelor’s degree with 12+ years of experience in a relevant field, such as Life Sciences, Nursing, or a related discipline.
- Significant management experience in oncology clinical trial setting with the ability to effectively collaborate with different Clinical R&D stakeholders in a matrix organization. Management expertise should cover management of budget, resources, headcount, processes (and controls), productivity, quality and project delivery.
- A complete understanding of ICH GCP and global/regional regulatory requirements is required.
- Strong communication skills requiring proficiency in written and spoken English. The incumbent must be competent and effective in written and verbal communication. Skills in more than one language are an advantage in this role.
- Strategic thinking and high emotional intelligence.
- Strong leadership that will attract, motivate, inspire, develop and retain talented staff. In addition, leadership skills that enable and drive alignment with the goals, purpose and mission of our company.
- Travel: up to 25% travel expected​

The expected hourly range for this role is $100.50 to $121.00 depending on skills, competency, and the market demand for your expertise. Eikon is proud to be an equal opportunity employer and will consider all qualified applicants for employment.

We are currently not accepting any new third-party agencies or firms at this time. Please do not forward unsolicited agency resumes to our website, employees or Human Resources. Eikon Therapeutics will not pay fees to any third-party agency or firm associated with unsolicited resumes.

## About Eikon Therapeutics

## Company Overview
- **One-liner**: Eikon Therapeutics is a late-stage clinical biopharmaceutical company that integrates single-molecule imaging, machine learning, and engineering to discover and develop novel therapies for oncology, immunology, and neuroscience.
- **Entity Type**: Public (NASDAQ: EIKN) – originally privately held, went public via a post-IPO equity round in 2026.
- **Headquarters**: Millbrae, California, United States
- **Founded**: 2019
- **Founders**: Not publicly named in the search results; the company was seeded by The Column Group.

## Core Business
- **Primary industry**: Biotechnology research and drug development (therapeutics)
- **Target customers**: Patients with unmet medical needs; the company partners with clinical research organizations, healthcare providers, and regulators.
- **Mission or purpose statement**: “Better insights will lead to better medicines” – the company aims to introduce new therapies that improve and extend life by deeply understanding human disease biology.

## Products & Services
- **EIK10 (TLR7/8 agonist)**: Phase 2 clinical program for solid tumors, leveraging immune response modulation.
- **VCP inhibitor (undisclosed target)**: Phase 1 program in oncology.
- **AR-v7 degrader**: Preclinical/early clinical program targeting androgen receptor splice variant in cancer.
- **PARP1 inhibitor**: Early-stage oncology program; also a CNS-penetrant PARP1 candidate for neuroscience.
- **AR degrader**: Preclinical androgen receptor degrader.
- **Discovery-stage programs**: Multiple undisclosed targets in oncology, immunology, and neuroscience, supported by the company’s single-molecule imaging platform.

## Market Standing
- **Valuation/Market Cap**: Not disclosed in search results; total funding of ~$1.5B as of mid-2026.
- **Key Metrics**:
  - Annual Revenue: $5.6M (reflective of early-stage, pre-commercial biotech).
  - Total Funding: $1.5B (seed, Series A $148M in 2021, Series B $518M in 2022, Series C $106M in 2023, and post-IPO equity of $381.2M in 2026).
- **Notable Investors/Partners**: The Column Group (lead seed/Series A), 18 investors in Series B, and multiple institutional partners across rounds; board includes industry veterans (e.g., Roger Perlmutter, former Merck CEO).
- **Growth Signals**:
  - Headcount grew ~2.7% YoY to 314 employees (2025–2026).
  - Active job postings increased 270% year-over-year (as of mid-2026).
  - Expanding pipeline into immunology and neuroscience beyond oncology.
  - Recent $351M financing event (reported by multiple outlets) to fund late-stage trials.

## Competitive Advantages
- **Proprietary single-molecule imaging platform** that enables real-time observation of protein dynamics at the single-molecule level, providing insights into disease mechanisms that traditional methods miss.
- **Machine learning integration** to analyze massive imaging datasets, accelerating target identification and drug design.
- **Deep bench of scientific talent**: Executives include Roger Perlmutter (CEO, ex-Merck), Roy Baynes (CMO, ex-Merck), and a team drawing from Genentech, Bristol Myers Squibb, Pfizer, and top academic institutions.
- **Cross-disciplinary approach** merging biology, engineering, and computation under one roof, reducing the “translation gap” between discovery and clinic.

## Strategic Focus
- **Advancing late-stage oncology pipeline**: Lead program (TLR7/8 agonist) in Phase 2, with plans to move into pivotal trials.
- **Expanding into new therapeutic areas**: Significant preclinical investment in immunology and neuroscience, with CNS-penetrant PARP1 and AR programs.
- **Continued platform development**: Scaling imaging and machine learning capabilities to enable faster, more precise drug discovery across multiple indications.
- **Building commercial infrastructure**: Post-IPO financing supports preparation for potential product launches and expanded clinical operations.

## Why Work Here
- **Culture**: Values-driven environment prioritizing execution, collaboration, innovation, transparency, respect, and caring for patients and colleagues.
- **Engineering & science fusion**: Opportunity to work at the intersection of advanced imaging, machine learning, and drug development – unique in biotech.
- **Growth trajectory**: Young company with strong funding, public listing, and rapidly expanding pipeline; employees can have significant impact.
- **Compensation**: Competitive base salaries (e.g., Software Engineer ~$140k, Senior Software Engineer ~$167k) plus equity incentives.
- **Work model**: Likely office-based at the Millbrae HQ or satellite labs in Hayward, CA; clinical roles may require travel; no explicit remote/hybrid policy in search results.
- **Perks**: Not detailed, but typical biotech benefits (health, 401k, PTO) are assumed; the company emphasizes a “transparent and inclusive culture” per its values.
- **Employee sentiment**: Overall rating 3.0/5 on LinkedIn (66 reviews); work-life balance 3.2, compensation 3.4, culture 3.0, career opportunities 2.9 – indicating room for improvement in career development.

## Sources
1. [eikontx.com](https://www.eikontx.com/)
2. [eikontx.com/about-us](https://www.eikontx.com/about-us/)
3. [eikontx.com/join-us](https://www.eikontx.com/join-us/)
4. [eikontx.com/pipeline](https://www.eikontx.com/pipeline/)
5. [linkedin.com/company/eikon-therapeutics-inc](https://www.linkedin.com/company/eikon-therapeutics-inc)

## Other roles at Eikon Therapeutics

- [Scientist I, High-Throughput Biology](https://feeny.ai/job/scientist-i-high-throughput-biology-eikon-therapeutics-millbrae-m74ftqevc49h) — Millbrae, CA
- [Manager, Study Start Up](https://feeny.ai/job/manager-study-start-up-eikon-therapeutics-jersey-city-sjbsvdttnvc6) — Jersey City, NJ
- [Clinical Trial Associate, APAC (CONTRACT)](https://feeny.ai/job/clinical-trial-associate-apac-contract-eikon-therapeutics-jersey-city-q6jkqzeyd2k2) — Jersey City, NJ / Millbrae, CA
- [Lab Operations Supervisor](https://feeny.ai/job/lab-operations-supervisor-eikon-therapeutics-millbrae-x3vbjdmv2xtb) — Millbrae, CA
- [Senior Scientist I, Cheminformatics](https://feeny.ai/job/senior-scientist-i-cheminformatics-eikon-therapeutics-millbrae-2m0m09mnsw8c) — Millbrae, CA
- [Senior Manager, Pharmacovigilance](https://feeny.ai/job/senior-manager-pharmacovigilance-eikon-therapeutics-jersey-city-85a1kxt3zerr) — Jersey City, NJ
- [Clinical Quality Operations Manager](https://feeny.ai/job/clinical-quality-operations-manager-eikon-therapeutics-millbrae-0mczwgq31knh) — Millbrae, CA / Jersey City, NJ
- [Senior Director, Translational Medicine](https://feeny.ai/job/senior-director-translational-medicine-eikon-therapeutics-jersey-city-1697yzqsxsjb) — Jersey City, NJ / Millbrae, CA
- [Associate Director, Clinical Data Management](https://feeny.ai/job/associate-director-clinical-data-management-eikon-therapeutics-jersey-city-6rkwk4ya8pa0) — Jersey City, NJ / Millbrae, CA
- [Scientist, Computational Biology](https://feeny.ai/job/scientist-computational-biology-eikon-therapeutics-millbrae-feqcsff97ncf) — Millbrae, CA