---
title: 'Downstream Associate Scientist (Contract 3 to 6 months) at Artis BioSolutions'
canonical: 'https://feeny.ai/job/downstream-associate-scientist-contract-3-to-6-months-artis-biosolutions-kcygep0skae3'
type: 'job'
last_seen: '2026-10-15'
---

# Downstream Associate Scientist (Contract 3 to 6 months) at Artis BioSolutions

- **Company:** Artis BioSolutions
- **Location:** Watertown, MA
- **Compensation:** $45–$55/hr
- **Employment:** temporary
- **Work type:** onsite
- **Posted:** 2026-10-13
- **Last confirmed live:** 2026-10-15
- **Apply:** https://jobs.lever.co/landmarkbio/1b8e6ae8-0c50-4b54-9a13-33ea77257076

## Job description

This role is a contract position. Artis BioSolutions is seeking a motivated Process Development Downstream Associate Scientist to support the development and optimization of purification processes for advanced therapeutic modalities, including adeno-associated viral vectors (AAV), lentiviral vectors (LVV), and extracellular vesicles (EV). The successful candidate will plan and execute laboratory experiments, analyze data, troubleshoot technical challenges, and contribute to process development activities, including continuous processing technologies. This hands-on, laboratory-based role requires strong problem-solving skills, a collaborative mindset, and flexibility in scheduling to accommodate experimental needs, including occasional weekend work.

## Responsibilities

- Plan and execute downstream process development experiments for advanced therapeutic modalities, including AAV, LVV, and EV.
- Develop, optimize, and troubleshoot purification processes, including clarification, depth filtration, tangential flow filtration (TFF), and chromatography.
- Support the development and evaluation of continuous and intensified downstream processing technologies.
- Perform laboratory experiments to evaluate process parameters and improve product recovery, purity, yield, and quality.
- Operate, maintain, and troubleshoot downstream processing equipment, including AKTA chromatography systems and TFF systems.
- Collect, analyze, and interpret experimental data, document results, and communicate findings to the project team.
- Prepare technical reports, experimental protocols, and standard operating procedures (SOPs).
- Collaborate with upstream process development, analytical development, and manufacturing teams to support project objectives and technology transfer.
- Maintain accurate laboratory records and ensure compliance with established safety and quality procedures.
- Support laboratory operations, including equipment maintenance, inventory management, and preparation of buffers and solutions.
- Demonstrate flexibility in scheduling to support experimental activities, including occasional weekend work.

Education

- Bachelor’s degree in biology, Bioengineering, Biotechnology, Chemical Engineering, or a related scientific discipline with 6+ years of relevant experience, or a master’s degree with 4+ years of relevant experience.

## Skills / Knowledge

- Demonstrated hands-on experience with downstream purification technologies, including clarification, filtration, and chromatography.
- Proven track record of success in biopharmaceutical process development.
- Strong analytical, troubleshooting, and problem-solving skills, with excellent attention to detail.
- Ability to work independently and collaboratively within a multidisciplinary team.
- Excellent organizational and time-management skills, with the ability to manage multiple priorities.
- Strong written and verbal communication skills, with the ability to document and present technical information effectively.
- Ability to handle confidential information and proprietary materials with professionalism and discretion.

## Preferred Qualifications

- Experience in downstream process development for advanced therapeutic modalities, including adeno-associated viral vectors (AAV), lentiviral vectors (LVV), and extracellular vesicles (EV).
- Hands-on experience with tangential flow filtration (TFF), depth filtration, and chromatography techniques, including affinity, ion exchange (IEX), and size exclusion chromatography (SEC).
- Experience operating and troubleshooting downstream processing equipment, including ÄKTA chromatography and TFF systems.
- Familiarity with continuous and intensified downstream purification technologies.
- Experience with process optimization, scale-up, and technology transfer to GMP manufacturing.
- Understanding of analytical methods used to evaluate process performance, product recovery, purity, and quality.
- Knowledge of Design of Experiments (DoE) and statistical approaches to process development.
- Familiarity with GMP requirements and regulatory expectations for biopharmaceutical manufacturing.
- Work environment: combination of laboratory and manufacturing
- On-site expectations: this is an on-site position
- Travel: 0% travel
- Schedule requirements: 9:00AM to 5:00PM
- Other requirements: flexibility to adjust working hours based on experimental needs, including some weekend work.

## Equal Employment Opportunity

Artis BioSolutions is an Equal Opportunity Employer. We are committed to creating an inclusive environment and providing equal employment opportunities to all qualified applicants and employees.

## About Artis BioSolutions

## Company Overview
- **One-liner**: Artis BioSolutions is an integrated platform for synthetic DNA production and advanced therapy manufacturing, accelerating genetic medicines from discovery through commercial GMP production.
- **Entity Type**: Private (backed by Oak HC/FT; acquired Landmark Bio in 2025)
- **Headquarters**: Carlsbad, California, United States (also operations in Watertown, MA and Bilbao, Spain)
- **Founded**: 2024
- **Founders**: Brian Neel (CEO) and Michael Houston (Co-Founder & CSO)

## Core Business
- **Primary industry**: Contract Development and Manufacturing Organization (CDMO) for genetic medicines; biotechnology
- **Target customers**: Biopharma companies developing mRNA therapies, gene editing, viral vectors, cell therapies (CAR-T, CAR-NK, iPSCs), vaccines, and emerging modalities
- **Mission**: To advance genetic medicines and biologics from early development to market by replacing fragmented supply chains with an integrated, synthetic DNA-powered platform.

## Products & Services
- **Synthetic DNA (oDNA)**: Proprietary enzymatic manufacturing of truly synthetic, plasmid-free DNA at RUO and GMP grades, delivered in 2 weeks (RUO) or 3-4 weeks (GMP) up to gram scale.
- **Cell Therapies**: Autologous and allogeneic cell therapy development and manufacturing, including CAR-T, CAR-NK, iPSCs, MSCs, and organoids.
- **Viral Vectors**: AAV and lentiviral vector production from research scale through GMP.
- **mRNA and LNP**: In vitro transcription, formulation, and translational development.
- **Emerging Modalities**: Support for extracellular vesicles, non-viral delivery platforms, and novel technologies.
- **Integrated Services**: CMC strategy, regulatory support, process and formulation development, analytical development, GMP manufacturing, and fill/finish.

## Market Standing
- **Valuation/Market Cap**: Not disclosed (private)
- **Key Metric**: Total funding undisclosed; backed by Oak HC/FT; acquired Landmark Bio in 2025 for an undisclosed sum.
- **Notable Investors/Partners**: Oak HC/FT (lead venture and growth equity firm)
- **Growth Signals**: 
  - Emerged from stealth in April 2025 with acquisition of Landmark Bio (~75 employees).
  - Combined headcount ~80 employees (as of early 2025), with LinkedIn showing +80% YoY growth.
  - Dual manufacturing sites in the US (Watertown, MA) and EU (Bilbao, Spain).
  - 2-week RUO synthetic DNA production timeline – significantly faster than industry standard.

## Competitive Advantages
- **Integrated platform** that replaces fragmented supply chains – one vendor from synthetic DNA through GMP fill/finish.
- **Proprietary enzymatic oDNA** eliminates plasmid dependency, reducing contamination risk and accelerating timelines.
- **Multi-modality capability** (mRNA, viral vectors, cell therapies, emerging) from a single infrastructure.
- **US and EU GMP manufacturing** enables global supply chain resilience.
- **Flexible engagement models** from defined-scope projects to deep co-development partnerships.

## Strategic Focus
- Build a portfolio of subsidiaries (starting with Landmark Bio) to create a single-source CDMO for complex genetic medicines.
- Reduce project timelines and manufacturing costs for customers while maintaining quality.
- Pursue additional strategic acquisitions in partnership with Oak HC/FT to expand capabilities and respond to market shifts (e.g., mRNA, gene editing).
- Scale enzymatic synthetic DNA production as a foundational technology for all genetic medicine modalities.

## Why Work Here
- **Mission-driven environment**: Directly contribute to bringing life-changing genetic therapies to patients faster.
- **Rapid growth**: Company emerged from stealth in 2025 and is actively scaling – potential for career advancement.
- **Geographic options**: Opportunities at the Carlsbad, CA headquarters, Watertown, MA (Landmark Bio site), and Bilbao, Spain.
- **Cutting-edge technology** – work with synthetic DNA, mRNA, viral vectors, cell therapy – not just a traditional CDMO.
- **Backed by top-tier investors** (Oak HC/FT) providing stability and long-term vision.
- **Culture highlights**: Small, agile team with strong scientific leadership; collaborative approach with clients; emphasis on quality and innovation.
- **Perks**: Not explicitly listed, but as a biotech CDMO, likely includes standard benefits, potential equity, and opportunities to work on groundbreaking therapies.

## Sources
1. [Artis BioSolutions Official Website](https://artisbiosolutions.com)
2. [Artis BioSolutions LinkedIn](https://linkedin.com/company/artis-biosolutions)
3. [Artis BioSolutions Leadership Page (Landmark Bio)](https://landmarkbio.com/staff-category/artis-biosolutions-leadership-team/)
4. [San Diego Business Journal – Artis BioSolutions Emerges from Stealth](https://sdbj.com/life-sciences/artis-biosolutions-emerges-from-stealth-with-acquisition/)

## Other roles at Artis BioSolutions

- [Associate Director, Quality Systems](https://feeny.ai/job/associate-director-quality-systems-artis-biosolutions-watertown-bvw59taspn0w) — Watertown, MA
- [Manager, Environmental Health & Safety (EHS)](https://feeny.ai/job/manager-environmental-health-safety-ehs-artis-biosolutions-watertown-chqjw596f5p4) — Watertown, MA
- [Research Associate - Analytics, Cell & Gene Therapies](https://feeny.ai/job/research-associate-analytics-cell-gene-therapies-artis-biosolutions-watertown-q7enzvx81qm8) — Watertown, MA