---
title: 'E11 Bio - Senior Research Associate - in vivo at Convergent Research'
canonical: 'https://feeny.ai/job/e11-bio-senior-research-associate-in-vivo-convergent-research-alameda-zd3kx0qc33xr'
type: 'job'
last_seen: '2026-09-12'
---

# E11 Bio - Senior Research Associate - in vivo at Convergent Research

- **Company:** Convergent Research
- **Location:** Alameda, CA
- **Compensation:** $90k–$144k
- **Employment:** full-time
- **Work type:** onsite
- **Posted:** 2026-01-23
- **Last confirmed live:** 2026-09-12
- **Apply:** https://jobs.lever.co/convergentresearch/cc0978b1-4003-44b7-8fa7-045312807a7a

## Job description

E11 Bio is on a mission to advance connectomics towards whole brain scale for humans and other mammals. We are a collaborative and interdisciplinary team of scientists and engineers engaged in a neuroscience moonshot project to develop a radical technology platform for scalable mammalian brain mapping. E11 Bio is a non-profit Convergent Research focused research organization located in Alameda, California, pursuing blue-skies neuroscience research yet operating like a nimble, tight-knit start-up. Read our technology roadmap.

High quality tissue samples are the foundation of our science. We are seeking a hands-on in vivo senior technician to take full ownership of our animal perfusions and in vivo workflows. This role is responsible for executing and continuously improving perfusion, fixation, and injection protocols, including preparation of perfusates and active troubleshooting of tissue-quality issues. Working closely with experimental scientists, this person will help design, execute, and debug in vivo labeling experiments, and will play a central role in ensuring the reliability and reproducibility of tissue used for our mission to map the mouse brain.

## Responsibilities

- Take ownership of all animal perfusions, including preparation of perfusates, execution of procedures, troubleshooting tissue-quality issues, and continuous improvement of fixation protocols.
- Execute and support in vivo surgical workflows, including stereotaxic and retro-orbital viral injections, post-operative monitoring, and animal welfare documentation.
- Apply scientific training  to monitor, control, and systematically optimize key in vivo and perfusion parameters for tissue labeling + preservation.
- Collaborate closely with experimental scientists to design, execute, and troubleshoot in vivo labeling experiments, contributing technical judgment and experimental insight.
- Perform routine animal health checks and husbandry tasks as needed, with attention to health or behavioral changes that may impact experimental outcomes.
- Maintain accurate experimental records, reproducible protocols, and operational readiness of perfusion and surgical equipment.
- Contribute to a positive, collaborative lab culture and run small, focused experimental projects.

Required Qualifications

- Hands-on experience performing animal perfusions using PFA or related fixatives for neuroscience or brain tissue applications, with the ability to produce consistent, high-quality tissue.
- Demonstrated ability to quickly learn, independently own, and optimize complex biological workflows, including diagnosing and resolving tissue-quality or protocol failures.
- Experience with rodent handling, restraint, and basic health assessment in a research setting.
- Strong record of reliability, precision, and careful experimental documentation.
- Clear communication skills and a proven ability to collaborate effectively within interdisciplinary research teams.

## Preferred Qualifications

- Mechanical or technical aptitude for maintaining, adjusting, or troubleshooting perfusion rigs, surgical setups, and related laboratory hardware.
- Experience with in vivo surgical techniques such as stereotaxic or retro-orbital viral injections (or strong interest and aptitude to train into these methods).
- Familiarity with downstream histology, imaging, or molecular tissue workflows.
- Interest in neuroscience and connectomics, with motivation to contribute to technically demanding, high-impact research.

In the first 3 months…

- By 1 month: You will have taken on core colony management at E11 (breeding, weaning, genotyping workflows, health checks, record keeping), completed training in stereotaxic and retro-orbital injections, and be learning and performing perfusions at our baseline quality level under supervision.
- After 2 months: You will be independently performing perfusions and generating consistent, high-quality tissue. You will be running routine surgeries with good survival and recovery, and managing the colony reliably end-to-end.
- After 3 months: You will be piloting controlled perturbations to the perfusion workflow—adjusting pressure, flow, temperature, perfusate composition, cannula/needle configurations—and documenting QC outcomes to improve ultrastructure, RNA retention, and protein preservation.
- After 1 year: You will own and direct execution and scheduling of perfusions at E11. You will be routinely producing well QCed tissue .

We offer:

- An opportunity to help change the world and work with some of the most talented and collaborative experts across scientific fields.
- An opportunity to gain experience on a field-defining moonshot effort.
- Excellent medical, dental, and vision insurance through a PPO plan; parental leave.
- Generous time off + paid holidays.
- 401K matching up to 6% of base salary
- Ample healthy and energizing food including daily lunches.
- Stipend for fitness and wellness activities.

E11 Bio, LLC is an Equal Employment Opportunity employer that proudly pursues and hires a diverse workforce. We do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other basis protected by applicable local, state, or federal laws or prohibited by Company policy. We strive for a healthy and safe workplace and strictly prohibit harassment of any kind.

## About Convergent Research

## Company Overview
- **One-liner**: Convergent Research is a nonprofit organization that launches and supports Focused Research Organizations (FROs) to build foundational technologies that unblock scientific progress.
- **Entity Type**: Private Nonprofit (501(c)(3))
- **Headquarters**: Palo Alto, California, United States
- **Founded**: 2021
- **Founders**: Adam Marblestone, Anastasia Gamick

## Core Business
- **Primary industry**: Scientific Research and Development Services (NAICS 5417)
- **Target customers**: B2B — scientific researchers, universities, government agencies, and philanthropic funders; operates as a "mission control" launching public-good R&D projects.
- **Mission statement**: “Spectacularly good futures are within reach, but only if we mind the gaps. Scientists need essential technologies to do the groundbreaking research all of us depend on.”

## Products & Services
Convergent Research does not sell commercial products. Instead, it incubates **Focused Research Organizations (FROs)** – time-bound, technically ambitious nonprofit efforts designed to produce high-impact public goods. Current and past FROs/projects include:

- **Cultivarium**: Developing tools for studying novel (previously unculturable) microorganisms.
- **E11 Bio (EVE Bio)**: Brain circuit mapping technologies.
- **Forest Neurotech**: Neural technology and biosensing platforms.
- **Ocean CDR Atlas**: Open-access tool for ocean-based carbon dioxide removal measurement.
- **Fundamental Development Gap Map (v1.0)**: A public web portal identifying bottlenecks holding back science.

Convergent Research provides shared operational support (legal, finance, HR, communications) across all FROs.

## Market Standing
- **Valuation/Market Cap**: Not applicable (nonprofit).
- **Annual Revenue (FY2024)**: **$72.4 million** (ProPublica IRS filing). Total revenue for FY2024 was $100.1 million.
- **Total Grant Funding Received**: At least $25.1 million from Vanguard Charitable, $9.5 million from Probabilistic Computing Foundation, $8 million from The Eric and Wendy Schmidt Fund for Strategic Innovation (latest filings).
- **Total Funding Raised**: ~$2 million in disclosed grants (led by Alfred P. Sloan Foundation in 2023); the vast majority comes from additional major philanthropic gifts not categorized as single-investor rounds.
- **Notable Partners/Funders**: Advanced Research and Intervention Agency (ARIA, UK), Alfred P. Sloan Foundation, The Eric and Wendy Schmidt Fund for Strategic Innovation, Vanguard Charitable, Probabilistic Computing Foundation.
- **Growth Signals**: 164 employees (as of latest CauseIQ data, up from ~23 on LinkedIn); headquarter presence in Palo Alto, Cambridge (MA), and Boulder (CO); expanded into the UK via a collaboration with ARIA (“FROST UK”); 15 active job postings with 25% month-over-month posting growth.

## Competitive Advantages
- **Novel institutional model**: Focused Research Organizations (FROs) fill a gap between traditional academia and for-profit startups — targeted, time-boxed, public-good missions.
- **Lean central infrastructure**: Shared operational support lets FRO scientists focus purely on technical breakthroughs, avoiding administrative overhead.
- **High-caliber scientific network**: Leaders include senior scientists from MIT, Caltech, King’s College London, and CMU as grantees/collaborators.
- **Access to major philanthropic capital**: Partners with some of the largest climate and science foundations globally.

## Strategic Focus
- **Geographic expansion**: Formal partnership with ARIA in the UK to launch FROs abroad (“FROST UK”).
- **Gap mapping**: Releasing and refining the Fundamental Development Gap Map to systematically identify the biggest bottlenecks in science.
- **Scaling the FRO model**: Adding new FROs in ocean CDR, neuroscience, and molecular engineering; hiring Founders in Residence to spin up new efforts.
- **Public data as product**: Committed to releasing open datasets and protocols (e.g., drug–target assay data, Lean proof library) as public goods.

## Why Work Here
- **Mission-driven**: Direct, hands-on impact on solving foundational scientific bottlenecks rather than incremental product improvements.
- **Culture**: Described as “mission control” — fast-paced, collaborative, technical. Leadership emphasizes pushing high-risk, high-reward projects.
- **Locations**: On-site positions in Palo Alto (CA), Cambridge/Boston (MA), and Boulder (CO). Some roles are US- or UK-based.
- **Team composition**: Small, senior-heavy centralized team (~20 core staff in Palo Alto) plus larger distributed FRO project teams (~164 total organization-wide). Significant cross-functional work across legal, finance, operations, and science.
- **Typical roles**: Postdoctoral Research Scientists, Research Associates, Biosensing Engineers, Finance/Operations Managers, General Counsel.
- **Compensation transparency (IRS filing)**: CEO Adam Marblestone — $431,025; President Anastasia Gamick — $360,495; competitive nonprofit scientific salaries.
- **Notable perks**: Working with world-class scientists and funders; contributions to genuinely public-good science; tax-deductible donation eligible organization.
- **Remote/hybrid**: Mostly on-site (Boulder, Palo Alto, Cambridge); limited remote possibilities depending on role.

## Sources
1. [convergentresearch.org](https://www.convergentresearch.org/)
2. [jobs.lever.co/convergentresearch](https://jobs.lever.co/convergentresearch)
3. [linkedin.com/company/convergent-research](https://linkedin.com/company/convergent-research)
4. [causeiq.com – Convergent Research](https://www.causeiq.com/organizations/convergent-research,883013217/)
5. [projects.propublica.org – Convergent Research Inc](https://projects.propublica.org/nonprofits/organizations/883013217)

## Other roles at Convergent Research

- [Sensor Network Technical Lead](https://feeny.ai/job/sensor-network-technical-lead-convergent-research-united-kingdom-jt6jqmaenyb3) — United Kingdom
- [Oath Technologies  - Research Engineer, Tools & Infrastructure](https://feeny.ai/job/oath-technologies-research-engineer-tools-infrastructure-convergent-research-93qbk9v0nk50) — Berkeley, CA
- [Oath Technologies  - Formal Methods Research Engineer](https://feeny.ai/job/oath-technologies-formal-methods-research-engineer-convergent-research-berkeley-nwx3xr3z77xt) — Berkeley, CA
- [Media and Outreach Specialist](https://feeny.ai/job/media-and-outreach-specialist-convergent-research-united-states-eca2sm7752az) — United States
- [Other - Good Fit for Melody](https://feeny.ai/job/other-good-fit-for-melody-convergent-research-pasadena-asp5ytrmyk9d) — Pasadena, CA
- [Clinical Operations Lead](https://feeny.ai/job/clinical-operations-lead-convergent-research-san-francisco-hjm69j52dc61) — San Francisco, CA
- [Research Hardware Engineer](https://feeny.ai/job/research-hardware-engineer-convergent-research-san-francisco-2g2wrejqv9m0) — San Francisco, CA
- [Research Scientist, Data Analysis](https://feeny.ai/job/research-scientist-data-analysis-convergent-research-san-francisco-avr34zdnwn1z) — San Francisco, CA
- [Human Neuroscientist](https://feeny.ai/job/human-neuroscientist-convergent-research-san-francisco-srr8mbjxczm9) — San Francisco, CA
- [Head of Clinical Science](https://feeny.ai/job/head-of-clinical-science-convergent-research-san-francisco-ymr7nxvkbxan) — San Francisco, CA