--- title: 'Engagement Director at Unlearn' canonical: 'https://feeny.ai/job/engagement-director-unlearn-remote-mvbgmbyrj0be' type: 'job' last_seen: '2026-09-09' --- # Engagement Director at Unlearn - **Company:** Unlearn - **Location:** Remote - **Compensation:** $180k–$200k - **Employment:** full-time - **Work type:** remote - **Posted:** 2026-09-03 - **Last confirmed live:** 2026-09-09 - **Apply:** https://jobs.ashbyhq.com/unlearn/82ee288c-35d1-4149-af32-3d18c9308891 ## Job description ## OUR MISSION AND VISION Unlearn exists to transform clinical development by making every trial smarter. We harness data, AI, and digital twins to enable faster, more robust studies that bring life-saving treatments to patients faster. This mission drives everything we do as we partner with biopharmaceutical companies to redesign how clinical trials are planned, run, and analyzed. We are defining the future of clinical development with unmatched scientific credibility, replacing uncertainty with AI-powered precision so decisions are clearer and trials are stronger. We don’t just disrupt the pharmaceutical industry, we create lasting change. We believe AI will define the future of medicine, and we are committed to building that future responsibly, rigorously, and in close collaboration with our partners in clinical development. ## ABOUT OUR TEAM We come from a variety of backgrounds ranging from machine learning to marketing—but regardless of where we come from, Unlearners share some common traits: - Unlearners are ambitious; we aren’t intimidated by big, challenging goals. - Unlearners are disciplined experimenters; we break down our big goals into smaller chunks and meet as often as necessary to track our velocity and iterate quickly. - Unlearners are gritty; we never give up, setbacks just make us try harder. - Unlearners are receptive to new ideas; in fact, we hate being stuck with the status quo - Unlearners are storytellers; sharing information with each other and with the world is super important, too important to be boring. And, last but not least, - Unlearners are team-oriented; we put the mission first, the company second, the team third, and individuals last. Headquartered in San Francisco, Unlearn was founded in 2017 by a team of world-class machine learning scientists. We have raised venture capital from top tier investors such as Altimeter, Insight Partners, Radical Ventures, 8VC, DCVC, and DCVC Bio, and completed our $50 million Series C in January 2024. If our purpose and culture resonate with you, we invite you to apply. ## THE ROLE We are seeking a seasoned, mission-driven Engagement Director to bring structure, visibility, and cross-functional leadership to how we deliver our services and products. We are looking for a leader who drives clarity and momentum across the company and can lead cross-functional delivery teams to ensure customer satisfaction, retention, and expansion. Because all of Unlearn’s customers are biopharmaceutical companies, deep fluency in the pharma and clinical development is essential. You will partner closely with our Technology, Science, Product, Commercial, Marketing, and G&A teams. This role reports directly to the Chief Commercial Officer and day-to-day will be the conduit between the delivery and commercial teams. The Engagement Director owns the customer relationship after contract signature. They translate sponsor priorities into terms the delivery team can act on, hold the account to its contracted commitments, and surface expansion opportunities for the commercial team to pursue. ## RESPONSIBILITIES ## CUSTOMER RELATIONSHIP MANAGEMENT - Build a deep and trusting relationship with customers, serving as a point of contact for customer satisfaction, retention, and expansion. - Coordinate customer-facing timelines, milestones, and deliverables, ensuring internal delivery plans align with customer commitments. - Identify opportunities to expand and strengthen customer collaborations and communicate these internally so the business can improve. ## CROSS-FUNCTIONAL LEADERSHIP & DELIVERY - Proactively identify risks, dependencies, and potential roadblocks in customer projects, and lead cross-team problem-solving workstreams to resolve them before they impact delivery. - Drive accountability and clear communication across the delivery teams, defining priorities and keeping customer projects on track. - Report progress on customer delivery, risks, and resource trade-offs to leadership on a regular cadence. ## ROADMAP OWNERSHIP & PROGRAM PLANNING - Track timelines, key milestones, interdependencies, and resource needs across customer engagements so leadership can plan resourcing and product delivery appropriately. - Stand up project management practices, cadences, and resource-planning tooling, creating a single source of truth for customer projects without heavyweight process overhead. ## REQUIREMENTS - 7+ years of experience delivering services or technology to clinical development groups at pharma or biotech sponsors: CRO, clinical tech vendor, or consulting. - Extensive experience working with biopharmaceutical companies, with deep, demonstrated fluency in the pharma and clinical development landscape. - Direct sponsor-facing ownership of accounts or engagements with a track record of leading a cross-functional team to delivery on customer engagements that include services, technology, and software products, and surfacing expansion opportunities in an existing account. - Experience working between a commercial team and a delivery or technical team. - Exceptional communication and stakeholder-management skills, with the ability to lead and influence cross-functional teams without direct authority. - Strong problem-solving instincts and a proactive approach to surfacing and resolving risks and roadblocks. - Exposure to biostatistics or quantitative methods is strongly preferred. - Bachelor’s degree in Business, Life Sciences, Engineering, or a related field; an advanced degree in a life-sciences or technical discipline is a plus. - Comfort operating in a fast-moving, startup environment where this role defines the Engagement Director function. - Based locally in San Francisco Bay Area, or remote and open to travel (25% of your time). ## BENEFITS & PERKS The following benefits and perks are for full time roles only. - Meaningful equity participation - 100% company-covered medical, dental, & vision insurance plans - 401k plan with matching - Flexible PTO plus company holidays - Annual company-wide break December 24 through January 1 - Commuter benefits - Paid Parental Leave Unlearn is an equal opportunity employer. At Unlearn, we are committed to building a diverse and inclusive workplace, because inclusion and diversity are essential to achieving our mission. If you’re excited about this role, and your past experience doesn’t align perfectly with every qualification in the job description, we encourage you to apply nevertheless. ## About Unlearn ## Company Overview - **One-liner**: Unlearn uses AI and digital twins of clinical trial participants to enable faster, smaller, and more robust studies for biopharma companies. - **Entity Type**: Private (Series C) - **Headquarters**: San Francisco, California, United States - **Founded**: 2017 - **Founders**: Aaron Smith, Charles Fisher, Graham Siegel, Jonathan Walsh ## Core Business - Primary industry/industries: Clinical research technology, AI-driven drug development, biotech - Target customers: Biopharmaceutical companies, contract research organizations (CROs), clinical trial sponsors - Mission or purpose statement: "To transform clinical development by making every trial smarter" – harnessing data, AI, and digital twins to bring life-saving treatments to patients faster. ## Products & Services - **TwinRCT**: A randomized controlled trial enhanced with AI-generated digital twins to increase statistical power, reduce control arm size, and shorten enrollment time. - **PROCOVA**: A methodology that uses prognostic scores from digital twins to improve the precision of treatment effect estimates. - **Digital Twin Generators**: AI models trained on historical patient-level data to predict individual health outcomes over time. - **TrialPioneer** (launched Jan 2026): An AI-powered workspace for upstream trial planning, enabling teams to compare trial-design scenarios, evaluate endpoints, and simulate outcomes before protocol finalization. - **SimLab**: A tool within TrialPioneer to build and compare trial-design scenarios with linked evidence. - **Scout**: Continuous literature and regulatory surveillance from PubMed, ClinicalTrials.gov, and drugs@FDA to align on precedent. - **Hindsight**: Exploration of harmonized clinical trial and real-world datasets to validate assumptions about population characteristics, endpoints, and benchmarks. - **Regulatory Services**: Support for navigating FDA and EMA guidelines to qualify twin-based approaches (EMA qualified, aligned with FDA guidance). ## Market Standing - **Valuation/Market Cap**: Not publicly disclosed - **Key Metric**: Total funding of $134.8M; latest Series C of $50M (February 2024). Annual revenue estimated at $5.4M (LinkedIn company data, 2025). - **Notable Investors/Partners**: - **Investors**: 8VC, DCVC Bio, Insight Partners (board representation from Francisco Gimenez, Kiersten Stead, Dylan Morris) - **Partners**: VectorY Therapeutics (ALS trial), remynd (Alzheimer’s study), Trace Neuroscience (ALS), ProJenX (ALS) - **Growth Signals**: - Published peer-reviewed article on applying AI-powered digital twins in healthcare. - Active partnerships with multiple biopharma companies in neuroscience, immunology, and metabolic disease. - Headcount of ~61 employees (LinkedIn, 2025) with positive follower growth (+20.1% YoY on LinkedIn). - Product expansion with TrialPioneer launch in early 2026. ## Competitive Advantages - **Proven Regulatory Credibility**: Digital twin methodology qualified by the EMA and aligned with current FDA guidance – a rare and defensible moat. - **Proprietary AI Models**: Trained on large-scale historical patient data to generate accurate prognostic digital twins, reducing trial variability. - **End-to-End Platform**: Single workspace covering trial planning (SimLab, Scout), monitoring (anomaly detection), and analysis (Hindsight, PROCOVA) – reducing fragmentation. - **Demonstrated Reductions**: Claims of ~33% reduction in control arm size and ~4+ months of enrollment time saved (approximate values from the website). ## Strategic Focus - **Immediate Priorities**: Expand commercial adoption of TwinRCT and TrialPioneer; deepen partnerships in neurology (ALS, Alzheimer’s) and immunology/metabolic disease. - **Technology Roadmap**: Continue integrating AI and digital twins into more trial decisions, with emphasis on upstream trial design and real-time monitoring. - **Growth Direction**: Scaling the platform to become the “scientific intelligence layer for clinical development” – connecting evidence, modeling, and reasoning across the trial lifecycle. ## Why Work Here - **Mission-Driven**: Employees work at the frontier of AI in medicine, directly impacting how life-saving treatments reach patients faster. - **Culture**: Described as “moonshot thinking” – setting radically ambitious goals to solve problems that affect millions of lives. Team of innovators in pharma, medtech, machine learning, and business. - **Benefits**: - 100% employer-paid medical, dental, and vision insurance for employee and family. - Company-paid life insurance, AD&D insurance, short/long-term disability. - 401k plan with 100% matching up to 4% of salary. - Paid parental leave. - Professional development budget for conferences, workshops, and classes. - Commuter benefits (ride or drive). - **Work Environment**: San Francisco-based office; commuter benefits suggest in-office presence. Contract-to-hire opportunities available for some roles. - **Open Roles**: Currently hiring a Product Designer (contract), Platform Engineer, and Product Manager – offering competitive salary, equity, and the chance to build on a data-intensive AI platform. ## Sources 1. [unlearn.ai](https://www.unlearn.ai/) – Product descriptions, case studies, press releases 2. [unlearn.ai/about](https://www.unlearn.ai/about) – Leadership, mission, board of directors 3. [unlearn.ai/careers](https://www.unlearn.ai/careers) – Open positions, benefits, culture 4. [crunchbase.com/organization/unlearn-ai](https://www.crunchbase.com/organization/unlearn-ai) – Funding history, company overview 5. [linkedin.com/company/unlearn-ai](https://www.linkedin.com/company/unlearn-ai) – Headcount, revenue estimate, employee growth ## Other roles at Unlearn - [AI Engineer](https://feeny.ai/job/ai-engineer-unlearn-san-francisco-j00jet7va89f) — San Francisco, CA - [Applied Machine Learning Scientist](https://feeny.ai/job/applied-machine-learning-scientist-unlearn-san-francisco-r0t759h7sy2m) — San Francisco, CA - [VP of Product](https://feeny.ai/job/vp-of-product-unlearn-san-francisco-4j4pfts8gdsb) — San Francisco, CA - [Senior Clinical Data Scientist](https://feeny.ai/job/senior-clinical-data-scientist-unlearn-san-francisco-y05jqxwqm5kh) — San Francisco, CA - [Clinical Data Scientist](https://feeny.ai/job/clinical-data-scientist-unlearn-san-francisco-yxs7nshek1c1) — San Francisco, CA - [Biostatistician](https://feeny.ai/job/biostatistician-unlearn-san-francisco-ejbd02q69jfr) — San Francisco, CA