--- title: 'Engineering Manager | Terra Platform at Manifold AI' canonical: 'https://feeny.ai/job/engineering-manager-terra-platform-manifold-ai-cambridge-v8tcxrfc6xnr' type: 'job' last_seen: '2026-10-14' --- # Engineering Manager | Terra Platform at Manifold AI - **Company:** Manifold AI - **Location:** Cambridge, MA - **Posted:** 2026-09-28 - **Last confirmed live:** 2026-10-14 - **Apply:** https://job-boards.greenhouse.io/manifoldai/jobs/8007321003 ## Job description ## About Manifold Manifold is the AI platform for life sciences, accelerating life-changing medicines to patients. Our products speed up workflows in areas from target identification and clinical development to market access and precision medicine in the clinic, while maintaining the governance life sciences requires. Global companies and premier research institutions use Manifold to operate faster and more effectively. Backed by leading investors including Reach Capital, TQ Ventures, Calibrate Ventures, SilverArc Capital, and Industry Ventures, Manifold serves tens of thousands of users across hundreds of organizations globally. ## About the Role Manifold is looking for an Engineering Manager to lead the Terra Platform team. Terra is the open-source, cloud-native platform for biomedical research originally built at the Broad Institute and now powered by Manifold. It supports 65,000 registered users across 50 countries, securely hosts 80+ petabytes of NIH data, and underpins some of the highest-impact science in the world. As Engineering Manager, you will lead the team that owns Terra day-to-day operations as well as delivering against a targeted feature roadmap. Operational responsibilities include service observability and monitoring, on-call support, dependency upgrades, and compliance audits. You will also work closely with Manifold Product Management as well as key Broad stakeholders to identify and solve the highest priority user problems. This is a player-coach role, and candidates are expected to split their time between team management and being hands-on with the code. Terra plays an critical role in Manifold’s partnership with the Broad Institute, and helps bring life-changing medicines to patients faster. ## What You'll Do - Own operational excellence for a platform that thousands of researchers depend on, including on-call rotations, incident triage, and risk mitigation initiatives. - Partner with Product Management to define and deliver against a prioritized roadmap, balancing the needs of multiple stakeholders while also paying down operational debt. - Partner with principal engineers on technical solutions, including architectural choices, design / code reviews, and individual code contributions. - Manage a full-stack engineering team (including contractors) via 1:1s, growing top performers, identifying gaps, and hiring. - Understand and clearly communicate Terra's role and how it contributes to Manifold's business strategy, including our commitments to the Broad and the NIH-funded community. - Evolve how the team builds, including tools, libraries, and processes, and bring an AI-native mindset to the team. ## What You'll Bring - 10+ years of software engineering experience, including 3+ years of management experience. - Experience managing contracts or off-shore resources. - Hands-on Scala, Java, and SQL experience. - A track record of building healthy, high-performing teams. - Experience in life sciences industry, open-source communities, or other regulated environments is a strong plus. - Experience working at the infrastructure layer (GCP, Terraform, etc) is also a plus. - Strong written and verbal communication skills. You can explain technical risk to non-technical stakeholders and product context to engineers. - You've integrated AI tools into your team's engineering workflows and have concrete examples of how that changed the team's output. - You've done your homework on what it means to accelerate life sciences research and you can articulate why that mission matters to you. ## Why Manifold - The opportunity to work at the frontier of AI in life sciences, helping the world's leading research and clinical institutions adopt transformative technology. - A high-autonomy, high-impact role where your work directly leads to positive customer outcomes and company growth. - Exposure to a wide range of technical and business challenges across oncology, genomics, and clinical data. - A collaborative team of engineers, scientists, and operators who are building something genuinely important. - Competitive compensation and equity in a high-growth company backed by leading investors. Salary Range The base salary range for this position is $210,000–$245,000 annually. - Please note: Final offer amounts are determined by multiple factors, including prior experience and expertise, and may vary from the amount above. This range does not represent additional compensation benefits (such as equity, 401K match or medical, dental or vision insurance). ## About Manifold AI ## Company Overview - **One-liner**: Manifold is the Enterprise Agent Platform for life sciences, accelerating life-changing medicines to patients by automating data preparation, analysis, and collaboration across regulated workflows. - **Entity Type**: Private (Series B, Dec 2025) - **Headquarters**: Newton, Massachusetts, United States - **Founded**: 2016 - **Founders**: Vivek Mohta (President & Co-Founder), Demba Ba (Co-Founder & Principal Data Scientist) ## Core Business - **Primary industry**: Enterprise AI platform for life sciences (pharma, biotech, clinical research) - **Target customers**: B2B – global pharmaceutical companies, premier research institutions, and clinical organizations - **Mission**: Accelerate life-changing medicines to patients, from early discovery to the clinic, by applying agentic AI to transform traditional processes [manifold.ai/about](https://www.manifold.ai/about) ## Products & Services - **[Agent OS](https://www.manifold.ai/platform)**: The core platform that automates the 80% of work that clogs R&D – interprets scientific intent, prepares datasets, configures tools, and applies organizational context to turn questions into insights in minutes. - **Data Ingestion & Preparation Agents**: Context-engineer datasets so downstream agents can work. - **Analysis Agents**: Run biostatistics, survival analysis, and bioinformatics pipelines end-to-end. - **Cohort & Query Agents**: Build and slice across billions of clinical and genomic records using plain language. - **Configurable Specialist Agents**: Tailored to fit specific organizational workflows and roles. - **Governance & Compliance Layer**: Unified governance layer with fine-grained access controls, encryption, HIPAA, SOC 2, GDPR, TX-RAMP, NIST SP 800-171, and BAA readiness. Deploys to your private cloud (AWS) – data never leaves your environment [manifold.ai](https://www.manifold.ai/). ## Market Standing - **Valuation**: Not disclosed - **Key Metrics**: - Annual Revenue: $5.0M–$25.0M (estimated) [linkedin.com/company/manifoldinc](https://www.linkedin.com/company/manifoldinc) - Total Funding: $40.5M across 4 rounds (Pre-Seed, Seed, Series A, Series B) - Employees: 77 (+38.9% YoY) [linkedin.com/company/manifoldinc](https://www.linkedin.com/company/manifoldinc) - **Notable Investors/Partners**: Reach Capital (led Series B), TQ Ventures (led Series A), Calibrate Ventures, SilverArc Capital, Industry Ventures, TTCER Partners [linkedin.com/company/manifoldinc](https://www.linkedin.com/company/manifoldinc) - **Growth Signals**: Serves tens of thousands of users across hundreds of organizations globally; reported up to 100x faster query turnaround (weeks → minutes) and production-ready deployments in weeks, not quarters [manifold.ai](https://www.manifold.ai/). ## Competitive Advantages - **Life-sciences‑native compliance**: Built from day one for HIPAA, IRB, BAA, PHI handling, and SOC 2 – AI runs inside customer compliance requirements, not around them. - **Bring‑Your‑Own‑Cloud deployment**: Platform deploys to the customer’s own AWS environment; data stays with the customer and is fully auditable. - **Agent OS specialization**: Unlike general AI platforms, Manifold’s agents are purpose-built for clinical, genomic, and real‑world data workflows, covering everything from data ingestion to biostatistics and cohort identification. - **Measured impact**: Demonstrated reductions in query turnaround from months to minutes, with specific customer case studies in multimodal oncology data and multi‑omics platforms [manifold.ai](https://www.manifold.ai/). ## Strategic Focus - **Current priorities**: Deepening agent capabilities across the full life‑science value chain (target identification → clinical development → market access → precision medicine) while maintaining rigorous governance and expanding the partner ecosystem. - **Direction for growth**: Scaling the platform to more global pharma companies and research consortia, and increasing automation of the 80% of R&D work that is currently manual [manifold.ai/platform](https://www.manifold.ai/platform). ## Why Work Here - **Culture**: High‑autonomy, high‑impact environment where engineers, scientists, and operators collaborate to build something genuinely new and important. Described as a “high‑pressure, multi‑threaded” but mission‑driven team [greenhouse.io](https://job-boards.greenhouse.io/manifoldai/jobs/7767743003). - **Remote/Hybrid/Office**: The Staff SRE role is based in Cambridge, MA; likely a hybrid presence (office in Newton/Cambridge area). Specific policy not publicly detailed. - **Notable perks**: Strong compensation packages with base salary range for Staff SRE $160,000–$225,000, plus equity, 401k match, medical/dental/vision insurance. Opportunity to work at the frontier of AI in life sciences and directly accelerate breakthrough science [greenhouse.io](https://job-boards.greenhouse.io/manifoldai/jobs/7767743003). - **Engineering culture**: Emphasis on infrastructure as code, AI‑augmented workflows, and solving complex problems in regulated environments. Engineers are expected to be hands‑on and comfortable with a wide‑ranging tech stack (AWS, Terraform, Snowflake, Airflow, dbt, PostgreSQL, etc.). - **Growth**: Fast‑growing company (+38.9% YoY headcount) with significant ownership and exposure to oncology, genomics, clinical data, and AI agent development. ## Sources 1. [manifold.ai](https://www.manifold.ai/) – Company homepage, product features, and impact metrics 2. [manifold.ai/about](https://www.manifold.ai/about) – Mission and company background 3. [manifold.ai/platform](https://www.manifold.ai/platform) – Platform capabilities (Agent OS, Governance, Collaboration, Infrastructure) 4. [linkedin.com/company/manifoldinc](https://www.linkedin.com/company/manifoldinc) – Company details, funding rounds, employee count, and growth 5. [greenhouse.io](https://job-boards.greenhouse.io/manifoldai/jobs/7767743003) – Staff Site Reliability Engineer job posting (compensation, culture, tech stack) ## Other roles at Manifold AI - [Senior Forward Deployed Engineer](https://feeny.ai/job/senior-forward-deployed-engineer-manifold-ai-cambridge-n3qkppbbhvjs) — Cambridge, MA - [Director Strategic Accounts | Broad Institute](https://feeny.ai/job/director-strategic-accounts-broad-institute-manifold-ai-cambridge-z91s98b1qz62) — Cambridge, MA - [Manager, Strategic Accounts](https://feeny.ai/job/manager-strategic-accounts-manifold-ai-cambridge-xz3jqymptgka) — Cambridge, MA - [Staff Software Engineer | Core Platform](https://feeny.ai/job/staff-software-engineer-core-platform-manifold-ai-cambridge-syzp38dw43a1) — Cambridge, MA - [Staff Site Reliability Engineer](https://feeny.ai/job/staff-site-reliability-engineer-manifold-ai-cambridge-hqn1zncxhmnr) — Cambridge, MA