---
title: 'Executive Director, Insights & Analytics at Tango Therapeutics'
canonical: 'https://feeny.ai/job/executive-director-insights-analytics-tango-therapeutics-boston-4f5kkx80kztw'
type: 'job'
last_seen: '2026-09-08'
---

# Executive Director, Insights & Analytics at Tango Therapeutics

- **Company:** Tango Therapeutics
- **Location:** Boston, MA
- **Compensation:** $275k–$413k
- **Posted:** 2026-09-06
- **Last confirmed live:** 2026-09-08
- **Apply:** https://job-boards.greenhouse.io/tangotherapeutics/jobs/7986609003

## Job description

Company Overview

Tango Therapeutics is a biotechnology company dedicated to discovering novel drug targets and delivering the next generation of precision medicine for the treatment of cancer.

Using an approach that starts and ends with patients, Tango leverages the genetic principle of synthetic lethality to discover and develop therapies that take aim at critical targets in cancer.

This includes expanding the universe of precision oncology targets into novel areas such as tumor suppressor gene loss and their contribution to the ability of cancer cells to evade immune cell killing.

The Tango labs and offices are located at 201 Brookline Avenue, in the Fenway area of Boston, Massachusetts.

Summary

The Executive Director, Insights and Analytics (ED I&A) is a strategic enterprise leader responsible for building, scaling, and leading Tango Therapeutics’ Insights and Analytics center of excellence. As Tango transitions from a research-stage biotech into a fully integrated commercial organization, this executive will define the enterprise-wide data, analytics, and insights strategy to support the successful launch and lifecycle management of our precision synthetic lethality oral medicines.

Reporting directly to the Chief Commercialization Officer (CCO), the ED of I&A will serve as a critical member of the Commercial Leadership Team and cross-functional strategy teams. This leader will act as an indispensable thought partner to executive leadership, translating complex data ecosystems into actionable insights that influence enterprise direction, optimize performance, and drive data-driven decision-making across Sales, Marketing, Market Access, Medical Affairs, and Finance. The ED of I&A is responsible for building and mentoring a high-performing leadership team encompassing critical functions across Market Research, Forecasting, and a Data & Advanced Analytics Center of Excellence (COE).

Your Role:

Cross-Functional Leadership & Strategic Integration

- Serve as a core member of cross-functional teams, acting as the strategic anchor for market analysis, competitive landscape evaluation, and commercial insights
- Partner closely with Medical Affairs, Market Access, Finance, Marketing, and Clinical Development to align on evidence needs, performance KPIs, and overarching corporate strategies
- Synthesize complex data into a clear overview of commercial strategy, opportunities, and risks for the Executive Leadership Team (ELT) and Board of Directors

Market Research & Competitive Intelligence

- Direct the Market Research function to build a best-in-class capability that generates deep insights from healthcare professionals (HCPs), patients, and payers to shape brand strategy and product positioning
- Establish a proactive competitive intelligence capability to continuously track the competitive landscape, clinical developments, reimbursement trends, and disruptive innovations within the oncology space

Forecasting & Demand Planning

- Provide strategic oversight in the development of robust global forecasting models for marketed products and pipeline assets
- Lead scenario planning, demand models, sensitivity analyses, and pipeline handover strategies to inform long-range planning, investment allocation, and launch readiness efforts

Data Strategy & Advanced Analytics (COE)

- Lead the Data & Advanced Analytics COE in developing the enterprise data strategy (acquisition, integration, governance, and quality), and driving the adoption of predictive modeling and AI-enabled decision-making
- Oversee the evaluation, procurement, and integration of commercial oncology data assets, including specialty pharmacy, claims, EHR, payer, and real-world evidence (RWE) sources
- Stand-up performance analytics and executive dashboarding capabilities, transitioning the organization from static reporting to dynamic, predictive, and action-oriented intelligence

What You Bring:

Education & Experience

- Bachelor’s degree required; advanced degree (MBA, MS, MPH, PharmD, PhD, or related discipline) strongly preferred
- 15+ years of progressive experience in pharmaceutical/biotech insights, analytics, forecasting, or related commercial operations roles
- Deep oncology expertise and a proven track record of leading analytics for oncology or specialty product launches
- Proven leadership track record of building, scaling, and developing high-performing analytics and insights organizations from the ground up

Core Competencies

- Deep understanding of the global and U.S. oncology market landscape, patient journeys, clinical treatment pathways, and competitive dynamics
- Expertise in pharmaceutical data sources (e.g., claims, EHR, specialty distribution data) and the analytic-to-business action process
- Exceptional executive presence and communication skills, with the demonstrated ability to influence C-level peers and effectively present data-driven narratives
- Strong managerial courage and a proven ability to attract, develop, and retain top analytic and data science talent

#LI-Hybrid

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Salary range $275,200—$412,800 USD

## About Tango Therapeutics

## Company Overview
- **One-liner**: Tango Therapeutics is a clinical-stage biotechnology company leveraging the principle of synthetic lethality to discover and develop next-generation precision cancer medicines for genetically defined patient populations.
- **Entity Type**: Public (NASDAQ: TNGX)
- **Headquarters**: Boston, Massachusetts, United States
- **Founded**: 2017
- **Founders**: Not publicly disclosed (launched by Third Rock Ventures)

## Core Business
- **Primary industry/industries**: Biotechnology, Precision Oncology, Drug Discovery & Development
- **Target customers**: B2B (pharma partnerships, clinical trial sites); ultimate customers are cancer patients with specific genetic tumor profiles
- **Mission or purpose statement**: "Discover transformative drugs for people with cancer by leveraging the classic principles of synthetic lethality in innovative ways… building a road map to cures that will transform the lives of patients and their families." [tangotx.com](https://www.tangotx.com/join-us/)

## Products & Services
- **Vopimetostat (PRMT5 inhibitor)**: A clinical-stage, wholly-owned program targeting MTAP-deleted cancers, including pancreatic, lung, and glioblastoma. Currently in Phase 1/2 trials. [tangotx.com](https://www.tangotx.com/pipeline/)
- **TNG456 (PRMT5 inhibitor)**: A next-generation PRMT5 inhibitor for MTAP-deleted cancers, currently in pre-clinical development.
- **Daraxonrasib (RAS inhibitor)**: A combination therapy (with vopimetostat) for MTAPdel/RASmut pancreatic and lung cancers. Recently reported a 92% objective response rate in pancreatic cancer in a Phase 1/2 trial. [tangotx.com](https://www.tangotx.com/)
- **CRISPR-based Target Discovery Engine**: A proprietary platform for identifying novel synthetic lethal targets, enabling a robust pipeline of wholly-owned programs.

## Market Standing
- **Valuation/Market Cap**: ~$1.05 billion (as of mid-2026) [linkedin.com](https://www.linkedin.com/company/tango-therapeutics)
- **Key Metric**: Annual Revenue of ~$62.4 million; Total Funding raised ~$901 million (including post-IPO). [linkedin.com](https://www.linkedin.com/company/tango-therapeutics)
- **Notable Investors/Partners**: Third Rock Ventures (lead Series A), Boxer Capital (lead Series B), BCTG Acquisition Corp (parent). Strategic partners include pharma and biotech companies (collaborations under active exploration). [linkedin.com](https://www.linkedin.com/company/tango-therapeutics)
- **Growth Signals**: Completed a $600 million upsized public offering in June 2026; strong clinical data (92% ORR in pancreatic cancer); pipeline expanding into glioblastoma; headcount growth in job postings (+400% YoY in active roles). [tangotx.com](https://www.tangotx.com/)

## Competitive Advantages
- **Synthetic Lethality Expertise**: A deep, proprietary understanding of CRISPR-based target discovery to identify novel vulnerabilities in cancers with tumor suppressor gene loss, undruggable oncogenes, and immune evasion mechanisms.
- **Genetically Defined Patient Selection**: All programs are designed for well-defined patient populations with clear biomarkers, increasing the probability of clinical success and reducing trial risk.
- **Wholly-Owned Pipeline**: Unlike many biotechs that license out rights, Tango retains full ownership of its lead programs, capturing maximum value.
- **Strong Financial Position**: With over $1B in market cap and a recent $600M offering, the company is well-capitalized to advance its pipeline through pivotal trials.

## Strategic Focus
- **Current priorities**: Advancing vopimetostat and daraxonrasib into Phase 3 trials for pancreatic and lung cancers; expanding the pipeline into glioblastoma; continuing to discover and validate new synthetic lethal targets; building out commercial manufacturing and clinical operations infrastructure.
- **Direction for growth**: Becoming a fully-integrated biotechnology company capable of bringing its own medicines to market, while selectively pursuing strategic collaborations to expand reach.

## Why Work Here
- **Culture highlights**: Emphasizes "urgency + compassion," "courage + leadership," "spirit + resilience," and "embrace individuality and face challenges together." Described as a team of "passionate problem solvers" who are "all in for exciting science and changing lives." [tangotx.com](https://www.tangotx.com/join-us/)
- **Remote/hybrid/office policy**: Primarily on-site at Boston HQ (201 Brookline Ave, Suite 901, Boston, MA). Roles appear to be Boston-based, though some field-based positions (e.g., Medical Science Liaisons) are remote.
- **Notable perks or engineering culture**: High scientific ambition with a clear patient-first mission; strong leadership team with deep oncology experience; active hiring across clinical operations, biostatistics, medical affairs, and legal/compliance; 15+ active job postings with significant YoY growth in roles. [greenhouse.io](http://job-boards.greenhouse.io/tangotherapeutics)
- **Workforce**: ~129 employees, with a mix of research (26%), medical (12%), and operations roles. Notable alumni from Novartis, Vertex, Takeda, and Broad Institute. [linkedin.com](https://www.linkedin.com/company/tango-therapeutics)

## Sources
1. [Tango Therapeutics Official Website](https://www.tangotx.com/)
2. [Tango Therapeutics Careers Page (Greenhouse)](http://job-boards.greenhouse.io/tangotherapeutics)
3. [Tango Therapeutics LinkedIn Profile](https://www.linkedin.com/company/tango-therapeutics)
4. [Tango Therapeutics Pipeline Page](https://www.tangotx.com/pipeline/)
5. [Tango Therapeutics Join Us Page](https://www.tangotx.com/join-us/)

## Other roles at Tango Therapeutics

- [Vice President, Marketing & Sales](https://feeny.ai/job/vice-president-marketing-sales-tango-therapeutics-boston-ex81335qs4hc) — Boston, MA
- [Senior Vice President, Market Access](https://feeny.ai/job/senior-vice-president-market-access-tango-therapeutics-boston-47tt1fw4qxxq) — Boston, MA
- [Senior Manager, Clinical Informatics](https://feeny.ai/job/senior-manager-clinical-informatics-tango-therapeutics-boston-g3pk44zmymam) — Boston, MA
- [Executive Director, FP&A](https://feeny.ai/job/executive-director-fp-a-tango-therapeutics-boston-kph81hnp4jvk) — Boston, MA
- [Manager, Total Rewards](https://feeny.ai/job/manager-total-rewards-tango-therapeutics-boston-fywb3xy2sabn) — Boston, MA
- [Associate Director, Pharmacovigilance Scientist](https://feeny.ai/job/associate-director-pharmacovigilance-scientist-tango-therapeutics-boston-5cgk3mmdsprr) — Boston, MA
- [Associate Medical Director, Pharmacovigilance](https://feeny.ai/job/associate-medical-director-pharmacovigilance-tango-therapeutics-boston-4kcjnjy0vpys) — Boston, MA
- [Executive Director, Clinical Development](https://feeny.ai/job/executive-director-clinical-development-tango-therapeutics-boston-xhzk5j65r72k) — Boston, MA
- [Clinical Trials Manager](https://feeny.ai/job/clinical-trials-manager-tango-therapeutics-boston-7yaaz94j244a) — Boston, MA
- [Senior Director, Clinical Sciences](https://feeny.ai/job/senior-director-clinical-sciences-tango-therapeutics-boston-j8hypf1vqq14) — Boston, MA