--- title: 'Executive Director, TechOps Alliance and Strategic Partnerships at Dyne Therapeutics' canonical: 'https://feeny.ai/job/executive-director-techops-alliance-and-strategic-partnerships-dyne-wxv9qjfras07' type: 'job' last_seen: '2026-09-14' --- # Executive Director, TechOps Alliance and Strategic Partnerships at Dyne Therapeutics - **Company:** Dyne Therapeutics - **Location:** Waltham, MA - **Compensation:** $260k–$305k - **Posted:** 2026-09-09 - **Last confirmed live:** 2026-09-14 - **Apply:** https://job-boards.greenhouse.io/dynetherapeutics/jobs/6186166004 ## Job description Company Overview: Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as preclinical programs for facioscapulohumeral muscular dystrophy (FSHD), Pompe disease and multiple DMD mutations. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. 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Role Summary: The Executive Director, TechOps Alliance and Strategic Partnerships shapes and leads the strategy, governance, and performance of key external partnerships that enable successful manufacturing, technical operations, development, and supply activities. This role serves as a senior enterprise partner, aligning internal and external stakeholders, anticipating risks and opportunities, and establishing the operating mechanisms required to deliver commitments across the product lifecycle. The role applies deep alliance-management and biopharmaceutical expertise to strengthen partner accountability, support informed executive decisions, and advance Dyne’s strategic and operational objectives. This position is based in Waltham, MA but open to remote with onsite visits required periodically. Primary Responsibilities Include: Alliance Strategy and Governance - Shape and lead the TechOps alliance and strategic partnership strategy in alignment with Dyne’s functional and company priorities. - Establish and evolve fit-for-purpose governance models, decision rights, committees, escalation pathways, operating plans, and performance standards for key partnerships. - Serve as the primary strategic point of contact for partner organizations and build trusted relationships with senior internal and external stakeholders. - Guide partnership planning across Manufacturing, Technical Development, Supply Chain, Quality, Development, and other relevant functions to ensure shared priorities and coordinated execution. Portfolio Execution and Performance - Direct cross-functional planning and execution across partnered manufacturing, technical operations, development, and supply activities, ensuring clear ownership, milestones, dependencies, and deliverables. - Define and monitor partnership objectives, metrics, budgets, contractual commitments, and business outcomes; identify trends and implement corrective actions when performance is off track. - Integrate partner plans with internal development and commercialization strategies, including late-stage and launch-readiness priorities. - Drive disciplined issue resolution and decision-making across complex, ambiguous, and high-impact operational challenges. Risk, Communication, and Executive Visibility - Anticipate strategic, operational, supply, quality, financial, and relationship risks; lead mitigation planning and escalate critical issues with clear options and recommendations. - Establish transparent communication pathways that enhance visibility, accountability, and timely decision-making across Dyne and partner organizations. - Provide concise, decision-oriented updates and recommendations on alliance health, milestone delivery, risks, opportunities, and resource needs to executive leadership. Leadership and Organizational Impact - Influence enterprise-wide priorities and foster alignment across functions, geographies, and partner organizations without relying on formal authority. - Champion alliance management best practices, scalable processes, and continuous improvement across TechOps and Dyne. - Model inclusive, accountable, and collaborative leadership while navigating sensitive negotiations and competing stakeholder perspectives. Experience and Skills Requirements: - Bachelor’s degree in a relevant discipline required; advanced degree such as an MS, MBA, or PhD preferred. - 18+ years of relevant pharmaceutical or biotechnology industry experience, or equivalent, including substantial leadership of people, programs, partnerships, or a function; experience at the prior leadership level is preferred. - 10+ years of management or functional leadership experience, including 5+ years in alliance management within Manufacturing, Supply Chain, Technical Operations, or a closely related area. - Deep expertise in alliance governance, strategic partnership development, performance management, and execution through external organizations. - Demonstrated success leading complex, cross-functional initiatives and multiple concurrent workstreams in a matrixed environment. - Strong knowledge of biopharmaceutical development from late-stage development through commercialization, including manufacturing, technical development, supply, and launch-readiness interdependencies. - Expertise in strategic planning, governance, contract and milestone oversight, budget management, risk management, and issue escalation. - Exceptional executive communication, negotiation, influence, relationship-building, and problem-solving skills with the ability to align diverse stakeholders and make sound decisions in ambiguous situations. #LI-Onsite MA Pay Range $260,000—$305,000 USD The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills. The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements.  Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload. Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law. ## About Dyne Therapeutics ## Company Overview - **One-liner**: Dyne Therapeutics is a clinical-stage biotechnology company developing targeted nucleic acid therapies for genetically driven neuromuscular diseases using its proprietary FORCE™ platform. - **Entity Type**: Public (NASDAQ: DYN) - **Headquarters**: Waltham, Massachusetts, United States - **Founded**: 2018 - **Founders**: Not publicly available (the company was co-founded by a team of scientists and entrepreneurs; individual names not surfaced in search results) ## Core Business - **Primary industry**: Biotechnology / Biopharmaceuticals – rare neuromuscular disease therapeutics - **Target customers**: B2B / B2G – regulatory agencies, healthcare providers, payers, and most importantly patients with Duchenne muscular dystrophy (DMD), myotonic dystrophy type 1 (DM1), facioscapulohumeral muscular dystrophy (FSHD), and Pompe disease. - **Mission / Purpose**: “Delivering functional improvement for people living with neuromuscular diseases.” [dyne-tx.com](https://www.dyne-tx.com/) ## Products & Services Dyne’s pipeline is built around its FORCE™ platform, which uses an antigen-binding fragment (Fab) conjugated to transferrin receptor 1 (TfR1) to deliver therapeutic payloads to muscle and the central nervous system. - **Z‑rostudirsen (DYNE‑251)** – An investigational therapeutic for DMD patients amenable to exon 51 skipping. Consists of a phosphorodiamidate morpholino oligomer (PMO) conjugated to an anti‑TfR1 Fab. Phase 1/2 DELIVER trial met primary endpoint; BLA submission for U.S. Accelerated Approval planned for Q2 2026 with potential launch in Q1 2027. [investors.dyne-tx.com](https://investors.dyne-tx.com/news-releases/news-release-details/dyne-therapeutics-reports-fourth-quarter-and-full-year-2025) - **Z‑basivarsen (DYNE‑101)** – Investigational therapeutic for DM1, using an antisense oligonucleotide (ASO) conjugated to anti‑TfR1 Fab. Phase 1/2 ACHIEVE trial fully enrolled; Phase 3 HARMONIA trial ongoing. [dyne-tx.com](https://www.dyne-tx.com/pipeline/) - **DYNE‑302** – Preclinical candidate for FSHD, using an siRNA payload to suppress DUX4 expression. [dyne-tx.com](https://www.dyne-tx.com/pipeline/) - **DMD Franchise Expansion** – Four additional development candidates (DYNE‑253, DYNE‑245, DYNE‑244, DYNE‑255) targeting exons 53, 45, 44, and 55 for DMD, entering IND‑enabling studies. [investors.dyne-tx.com](https://investors.dyne-tx.com/news-releases/news-release-details/dyne-therapeutics-reports-fourth-quarter-and-full-year-2025) ## Market Standing - **Valuation / Market Cap**: Not disclosed in search results (public company; market cap fluctuates with stock price; current figure not provided in the sources). - **Key Metric**: Cash, cash equivalents and marketable securities of **$1.1 billion** as of December 31, 2025, providing runway into Q1 2028. [investors.dyne-tx.com](https://investors.dyne-tx.com/news-releases/news-release-details/dyne-therapeutics-reports-fourth-quarter-and-full-year-2025) - **Notable Investors / Partners**: Not listed in provided search results (likely institutional investors; prior venture rounds not detailed here). - **Growth Signals**: - Headcount grew **38.2% YoY** to **227 employees** (2025). [linkedin.com](https://www.linkedin.com/company/dynetx) - Positive topline results from DELIVER trial for z‑rostudirsen; potential first product launch in Q1 2027 if approved. - Advancing five distinct clinical/preclinical programs across multiple neuromuscular indications. ## Competitive Advantages - **FORCE™ Platform**: Differentiated delivery technology that uses a TfR1‑binding Fab to enable broad and deep tissue penetration in both muscle and CNS – addressing one of the biggest hurdles in neuromuscular drug development. - **Best‑in‑Class Potential**: Clinical data for z‑rostudirsen showed statistically significant dystrophin expression (5.46% of normal at 6 months, 7‑fold change) and preservation of lung function (FVC%p) compared to placebo, despite a small trial not powered for functional endpoints. - **Broad Pipeline**: Covering multiple exon‑skipping opportunities in DMD as well as entirely different diseases (DM1, FSHD, Pompe) with the same core platform, reducing risk and enabling rapid expansion. ## Strategic Focus - **Regulatory Submission**: File a Biologics License Application (BLA) for z‑rostudirsen in Q2 2026 under U.S. Accelerated Approval pathway. - **Late‑Stage Trials**: Initiate two field‑defining Phase 3 confirmatory trials (FORZETTO for DMD and HARMONIA for DM1) in 2026 following FDA alignment on design. - **Pipeline Expansion**: Move four additional DMD exon‑skipping candidates into IND‑enabling studies and advance preclinical DYNE‑302 (FSHD) toward the clinic. - **Commercial Readiness**: Prepare for potential first‑ever company launch in Q1 2027 with a focus on U.S. market, while also pursuing ex‑U.S. approval pathways. ## Why Work Here - **Mission‑Driven Culture**: The company’s “One Dyne community” ethos emphasizes accountability, transparency, fearlessness, and a relentless drive to deliver functional improvement for patients and families. [dyne-tx.com](https://www.dyne-tx.com/careers-culture/) - **Competitive Benefits**: Medical, dental, vision, 401(k), flexible vacation, paid holidays including a year‑end office closure, short‑ & long‑term disability, HSA/FSA accounts. [dyne-tx.com](https://www.dyne-tx.com/careers-culture/) - **Work Environment**: Office location in Waltham, MA (Boston area). Remote/hybrid policy not specified in search results; likely on‑site or hybrid for lab‑based roles. Career page lists roles such as Associate Director, Oligonucleotide Development; Scientist, RNA; Director of Training – reflecting a mix of research, clinical, and corporate functions. [job-boards.greenhouse.io](https://job-boards.greenhouse.io/dynetherapeutics) - **Growth Opportunity**: Joining a late‑stage biotech with a validated platform, strong cash position, and a clear path to commercialization – offering employees exposure to both R&D and upcoming launch activities. - **Recruitment Scam Warning**: Dyne posts an explicit notice on its careers page that it never requests financial details or payment during hiring; all legitimate emails come from @dyne‑tx.com addresses. ## Sources 1. [dyne-tx.com – Company Overview](https://www.dyne-tx.com/) 2. [dyne-tx.com – Careers & Culture](https://www.dyne-tx.com/careers-culture/) 3. [dyne-tx.com – Pipeline](https://www.dyne-tx.com/pipeline/) 4. [investors.dyne-tx.com – Q4/Full Year 2025 Results](https://investors.dyne-tx.com/news-releases/news-release-details/dyne-therapeutics-reports-fourth-quarter-and-full-year-2025) 5. [linkedin.com – Dyne Therapeutics Company Profile](https://www.linkedin.com/company/dynetx) 6. [job-boards.greenhouse.io – Dyne Careers Page](https://job-boards.greenhouse.io/dynetherapeutics) ## Other roles at Dyne Therapeutics - [Associate Director, HCP Marketing - DMD](https://feeny.ai/job/associate-director-hcp-marketing-dmd-dyne-therapeutics-remote-r1dnck9gh1bz) - [Associate Director, Clinical Operations Study Lead](https://feeny.ai/job/associate-director-clinical-operations-study-lead-dyne-therapeutics-waltham-evbyf6dxekgd) — Waltham, MA - [Senior Director, Quality Control](https://feeny.ai/job/senior-director-quality-control-dyne-therapeutics-waltham-0c14xebc380b) — Waltham, MA - [Senior Director, Medical Affairs Learning & Development](https://feeny.ai/job/senior-director-medical-affairs-learning-development-dyne-therapeutics-waltham-mvej99ejr8y0) — Waltham, MA - [Director, Clinical Scientist](https://feeny.ai/job/director-clinical-scientist-dyne-therapeutics-waltham-jw10cdn5v3ms) — Waltham, MA - [Scientist, Bioconjugation](https://feeny.ai/job/scientist-bioconjugation-dyne-therapeutics-waltham-jg9q1pw4whag) — Waltham, MA - [Principal Scientist, Oligonucleotide (PMO, ASO) Development](https://feeny.ai/job/principal-scientist-oligonucleotide-pmo-aso-development-dyne-therapeutics-2x39whh9swds) — Waltham, MA - [Director, Drug Safety & Pharmacovigilance Scientist](https://feeny.ai/job/director-drug-safety-pharmacovigilance-scientist-dyne-therapeutics-waltham-6e6cxz3bs5mx) — Waltham, MA - [Director, People Operations](https://feeny.ai/job/director-people-operations-dyne-therapeutics-waltham-x79gkrh2bafa) — Waltham, MA - [Associate Director, Talent Acquisition Operations & Programs](https://feeny.ai/job/associate-director-talent-acquisition-operations-programs-dyne-therapeutics-t369xmxga1xg) — Waltham, MA