--- title: 'Field Scientific Director (MSL), Payer and Evidence at Amylyx Pharmaceuticals' canonical: 'https://feeny.ai/job/field-scientific-director-msl-payer-and-evidence-amylyx-pharmaceuticals-m4hbzjpjtf2k' type: 'job' last_seen: '2026-11-10' --- # Field Scientific Director (MSL), Payer and Evidence at Amylyx Pharmaceuticals - **Company:** Amylyx Pharmaceuticals - **Location:** Cambridge, MA - **Compensation:** $228k–$257k - **Posted:** 2026-11-09 - **Last confirmed live:** 2026-11-10 - **Apply:** https://job-boards.greenhouse.io/amylyx/jobs/6250922004 ## Job description Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS). Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply. The Opportunity The Field Scientific Director, Payer & Evidence is a field-based role within Medical Affairs responsible for advancing Amylyx’s Market Access, Health Economics & Outcomes Research (HEOR) and Real-World Evidence (RWE) strategies through impactful engagement with payer decision-makers. This role serves as a critical bridge between clinical evidence, value demonstration, and market access, translating complex data into meaningful insights that support patient access and inform strategic decision-making. ## Responsibilities Key Job Duties include, but are not limited to: Field Payer Scientific Engagement - Work with national, regional and local healthcare decision-makers focused on payer initiatives, RWE, HEOR, and removing clinical and economic barriers to patient access for Amylyx. - Plan and execute territory level engagement strategy for assigned customers, in alignment with Market Access and Medical Affairs Strategy. - Establish and maintain scientific relationships with payer medical directors, pharmacy directors, formulary committee members, IDNs, ACOs, and other local/regional healthcare decision-makers. - Deliver scientific presentations to formulary committees and other key healthcare decision-makers (HCDMs), communicating health economic model and supporting clinical data, and serve as the primary field-based point of contact for related questions. - Maintain a consistent and productive field presence across the geography to customer meetings, regional and national conferences as needed.6-8 bullets – essential job functions / ownership. Customer Engagement Excellence - Identify, develop and maintain collaborative relationships with payer decision-makers by understanding payer needs and priorities, developing and executing a territory strategic plan and customizing the engagement strategy to address their unique needs. - Utilize and effectively present clinical, humanistic and economic evidence as well as the value proposition of our products in a clear and compelling manner to the payer audience. - Develop and implement the field HEOR/RWE strategy in collaboration with internal and other field-based Medical and Commercial (Market Access, Medical Affairs, Sales) partners to provide exceptional customer experience. - Serve as a trusted resource, sharing expertise with customers. Innovative Partnerships - Collaborate with payer decision-makers within a designated geographic “healthcare ecosystem” to understand and address their unique informational needs and challenges. - Explore opportunities for collaboration on value-based care and research initiatives to facilitate mutually beneficial partnerships. - Gather and communicate field payer insights, evidence gaps, horizon scanning of health care environmental trends to drive actionable recommendations and inform medical and commercial strategy. - Partner with field Market Access Account team as well as other field-based teams, including RSDs and Sales to ensure alignment, coordination and consistency in messaging in a compliant manner. - Partner on RWE/ HEOR research initiatives and publication . US Healthcare System and Payer Expertise - Serve as a knowledgeable resource for payer decision-makers and internal cross-functional teams on relevant disease states, value-based assessments, healthcare and payer policies, and other payer oriented emerging topics. - Stay abreast of emerging science, environmental market issues, pricing and regulatory actions relevant to regional and national payer decision-makers. - Provide training and support to internal teams on payer and value-based healthcare concepts. Required Qualifications - Advanced degree in Bio sciences required (PharmD, PhD, MD, DNP, DHSc). - At least 7 years of experience in a scientific or health-related field-based customer facing role in industry; payer experience required. - Deep understanding of the US healthcare system and US value-based decision makers in private and public payers, integrated delivery network (IDNs) and other payer-related customers at the regional and national level. - Demonstrated expertise in HEOR, real-world evidence (RWE) and value assessment, including experience with AMCP Dossiers, FDAMA 114, budget impact and economic models. - Knowledgeable with experience in the application of HEOR/RWE research and data analytics to effectively communicate study findings on a range of clinical and HEOR topics. - High level of scientific excellence, including strong communication skills in translating and presenting complex scientific information in a clear and compelling manner. - Exceptional interpersonal skills with a high level of emotional intelligence and the ability to effectively engage with diverse stakeholders. - High level of business acumen, including broad knowledge of the healthcare environment, understanding of biopharmaceutical industry, strong skills in developing, managing, and executing strategic plans. - Proven ability to work effectively with cross-functional internal teams (e.g., Market Access, Clinical, Medical Affairs, Commercial) to foster a highly collaborative team environment. - Keen ability to quickly and consistently build and maintain high levels of trust with internal and external stakeholders. - Highly resourceful, self-motivated and the ability to thrive in an entrepreneurial environment. ## Preferred Qualifications - Rare disease experience. - Field medical affairs experience as medical science liaison. - East Coast near a metropolitan airport. Work Location and Conditions - At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations candidates must be able to attend meetings at our office in Cambridge, MA on a regular basis.  Preference will be given to candidates who reside in the New England region and can be in person on an as needed basis. - When working remotely, you must have access to a work setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location. - Ability to travel up to > 70%, including overnight stays as needed to cover the assigned geography. ## Compensation The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity. Base salary is one component of Amylyx’s total rewards package. In addition to competitive base pay, eligible employees may receive annual performance-based bonuses and equity awards, providing an opportunity to share in the company’s long-term success. Amylyx also offers a comprehensive benefits package designed to support the health, well-being, and financial security of our employees. Estimated Pay Range $228,000—$257,000 USD To stay connected with us, follow Amylyx Pharmaceuticals on [LinkedIn](https://www.linkedin.com/company/amylyx). To return to our website please [click here](https://www.amylyx.com/). Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know. It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability. ## About Amylyx Pharmaceuticals ## Company Overview - **One-liner**: Amylyx Pharmaceuticals is a clinical-stage pharmaceutical company focused on developing novel therapies for serious diseases with high unmet needs, including neurodegenerative and rare diseases. - **Entity Type**: Public (NASDAQ: AMLX) - **Headquarters**: Cambridge, Massachusetts, United States - **Founded**: 2013 - **Founders**: Josh Cohen and Justin Klee ## Core Business - Primary industry/industries: Biotechnology / Pharmaceuticals - Target customers: Patients, healthcare providers, and payers (B2B/B2C); primarily focused on rare and neurodegenerative diseases - Mission or purpose statement: To develop novel therapies for high unmet needs with urgency, rigorous science, and unwavering commitment to the communities they serve. ## Products & Services - **AMX0035 (RELYVRIO®/ALBRIOZA)**: An investigational combination therapy for Wolfram syndrome and previously approved for ALS (voluntarily withdrawn after Phase 3 PHOENIX trial did not meet primary endpoint). Still being studied in Wolfram syndrome. - **Avexitide**: A Phase 3-ready GLP-1 receptor antagonist with FDA Breakthrough Therapy designation for post-bariatric hypoglycemia (PBH) and congenital hyperinsulinism (HI). Dosing in Phase 3 LUCIDITY trial. - **AMX0114**: An investigational therapy for ALS, currently in Phase 1 LUMINA clinical trial, with FDA Fast Track designation. - **AMX0318**: A long-acting GLP-1 receptor antagonist in IND-enabling studies for PBH and other rare diseases, developed in collaboration with Gubra A/S. ## Market Standing - **Valuation/Market Cap**: Not publicly available from provided sources (public company; market cap fluctuates) - **Key Metric**: Completed IPO on NASDAQ in April 2025 (ticker: AMLX); annual revenue not disclosed (clinical-stage, no approved products currently marketed) - **Notable Investors/Partners**: Gubra A/S (research collaboration), Dr. Rudy Tanzi (Founding Chair of Scientific Advisory Board) - **Growth Signals**: Expanded pipeline with avexitide acquisition (July 2024); multiple FDA designations (Fast Track, Orphan Drug); first patients dosed in Phase 1 LUMINA (ALS) and Phase 3 LUCIDITY (PBH); ongoing IND-enabling studies for AMX0318. ## Competitive Advantages - Focus on high unmet needs with a rigorous, science-driven approach to drug development. - Strong pipeline diversification across multiple rare and neurodegenerative diseases. - Experienced team with collective expertise from therapeutic development through commercialization. - Deep engagement with patient communities and care providers to understand unmet needs. - Agile, hybrid-remote work environment that attracts and retains top talent. ## Strategic Focus - Advancing late-stage clinical trials (avexitide Phase 3, AMX0035 Phase 2 in Wolfram syndrome). - Expanding pipeline through business development and collaborations (e.g., Gubra). - Leveraging regulatory designations (Breakthrough Therapy, Fast Track, Orphan Drug) to accelerate development. - Continuing to build a culture of urgency, accountability, and innovation to serve patients with high unmet needs. ## Why Work Here - **Culture**: Values-driven environment emphasizing accountability, audacity, authenticity, curiosity, and engagement. Rooted in connection with colleagues and the communities served. - **Work Model**: Hybrid-remote with headquarters in Cambridge, MA. Three annual Anchor Weeks in-person and bi-weekly Amylyx Exchange meetings for connection. - **Benefits**: Flexible PTO, 5% 401(k) employer contribution, paid parental leave, medical/dental/vision, HSA/FSA, employee assistance program, mobile reimbursement, learning and development program, recognition platform. - **Engineering/Research Culture**: Emphasis on rigorous science, continuous learning, and generous knowledge sharing. Opportunities to work on cutting-edge therapies from preclinical through commercialization. ## Sources 1. [Amylyx Pharmaceuticals - Our Company](https://www.amylyx.com/our-company) 2. [Amylyx Pharmaceuticals - Careers](https://www.amylyx.com/careers) 3. [Amylyx Pharmaceuticals - Homepage](https://www.amylyx.com/) 4. [Jobs at Amylyx Pharmaceuticals - Greenhouse](https://job-boards.greenhouse.io/amylyx) 5. 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