---
title: 'FL114: Senior Research Associate, Genomics at Flagship Pioneering, Inc.'
canonical: 'https://feeny.ai/job/fl114-senior-research-associate-genomics-flagship-pioneering-inc-cambridge-0q5q7ej897wv'
type: 'job'
last_seen: '2026-11-06'
---

# FL114: Senior Research Associate, Genomics at Flagship Pioneering, Inc.

- **Company:** Flagship Pioneering, Inc.
- **Location:** Cambridge, MA
- **Posted:** 2026-11-05
- **Last confirmed live:** 2026-11-06
- **Apply:** https://boards.greenhouse.io/flagshippioneeringinc/jobs/8924760002?gh_jid=8924760002

## Job description

## About FL114

FL114 is an innovative, privately held biotechnology company developing our novel epigenetic editing platform to treat a variety of diseases through precise, tunable modification of gene expression. FL114 was founded by Flagship Pioneering, where companies such as Moderna Therapeutics (NASDAQ: MRNA) and Seres Therapeutics (NASDAQ: MCRB) were conceived and created.  With a strong emphasis on innovation and experimental execution, FL114 cultivates a highly dynamic and entrepreneurial environment.

About the Role:

FL114, Inc. is seeking an outstanding Senior Research Associate to join our Genomics team. We’re looking for a skilled, NGS-focused molecular biologist to assist in the development and advancement of our epigenetic editing programs, from early discovery research to preclinical development and beyond. The successful candidate will be an essential member of a close-knit team of experimental and computational scientists. We are looking for enthusiastic, detail oriented, adaptive, and highly motivated individuals with a passion for bringing novel medicines to patients. Applicants should be comfortable working on a fast-paced, cross-functional scientific team.

Key Responsibilities:

- Execution of NGS-based functional genomics assays in a high-throughput production environment that address core R&D needs in cell state mapping and therapeutic molecular validation
- Collaborate with research teams to help develop and support fit-for-purpose NGS solutions and molecular and cellular assay technologies
- Contribute to the development and execution of specialized molecular assays

Required Skills:

- 2+ years of hands-on experience performing NGS library prep for Illumina platforms
- Familiarity with ATAC-seq, RNA-seq, ChIP-seq, Methyl-Seq, and/or 10X Single-cell
- Direct experience operating Illumina instruments
- Familiarity with liquid handlers and Kingfisher automation
- Proficiency with quantification/QC platforms (Qubit, TapeStation/BioAnalyzer)
- Hands-on experience with core molecular biology techniques such as nucleic acid extraction/purification, PCR/qPCR, restriction digestion/ligation
- Comfortable troubleshooting and optimizing assays/protocols
- Experience in an industrial, drug-development environment preferred
- Experience in immunological indications preferred

## About Flagship

Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond.

What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our team of scientists, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and create breakthroughs for the benefit of people and planet.  Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company’s annual list of the World’s Most Innovative Companies.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.

The salary range for this role is $81,000 - $107,250. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. FL114 currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on FL114's good faith estimate as of the date of publication and may be modified in the future.

Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.

## About Flagship Pioneering, Inc.

## Company Overview
- **One-liner**: Flagship Pioneering is a life sciences venture creation firm that conceives, creates, and capitalizes breakthrough bioplatform companies in biotechnology, health, and sustainability.
- **Entity Type**: Private (Venture Creation Firm)
- **Headquarters**: Cambridge, Massachusetts, United States
- **Founded**: 2000
- **Founders**: Noubar Afeyan (Co-Founder & CEO)

## Core Business
- **Primary industry/industries**: Biotechnology Research, Life Sciences Venture Creation, Company Incubation
- **Target customers**: B2B / B2G – partners with academic institutions, pharma companies, and investors; also acts as an employer for scientists, entrepreneurs, and corporate builders
- **Mission or purpose statement**: “To harness the 21st century's most powerful technological forces for good to deliver a better future for all.”

## Products & Services
Flagship does not sell products directly; its offerings are the companies it creates and the innovation platform it operates.
- **Innovation Platform**: A systematic, institutionalized process to identify “unreasonable” scientific questions, test them rigorously, and spin out independent companies that develop therapeutics, diagnostics, agricultural technologies, and more.
- **Portfolio Companies**: Over 120 companies founded, including Moderna, Generate:Biomedicines, Inari Agriculture, Tessera Therapeutics, Lila Sciences, and others. Each is a separate enterprise with its own products (e.g., mRNA vaccines, gene-editing tools, AI-driven drug discovery).

## Market Standing
- **Valuation/Market Cap**: Not publicly disclosed (privately held)
- **Key Metric**: Annual revenue of approximately $800 million (2025/2026 estimate) and 620 employees (+9.7% YoY growth)
- **Notable Investors/Partners**: Flagship is itself an investor and partner; key collaborations include AWS (to accelerate drug discovery), Harvard Medical School, Broad Institute, and multiple top-tier biopharma companies. Portfolio company Moderna is a publicly traded giant.
- **Growth Signals**: 78 active job postings (+50% quarterly), recent formation of Terion (digital agriculture infrastructure) and Serif Biomedicines (modified DNA platform), and expanded presence in Europe and Asia.

## Competitive Advantages
- **Unique Model**: Combines scientific exploration, company creation, and capital investment under one roof – “a way that is largely without precedent”
- **Deep Talent Pool**: Exceptional network of scientist-entrepreneurs and company builders; top hires from MIT, Harvard, Biogen, Novartis, and Pfizer
- **Track Record**: Over two decades of founding transformational companies (e.g., Moderna’s COVID‑19 vaccine), demonstrating repeatable innovation
- **Process-Driven**: Systematic methodology for turning “what‑if” questions into patentable bioplatforms, reducing risk compared to ad‑hoc startup creation

## Strategic Focus
- **Current priorities**: Expanding AI/machine learning integration across drug discovery and life sciences (highlighted by AWS collaboration); entering preemptive health and medicine; advancing sustainable agriculture and climate solutions; growing international operations (UK, Singapore, Canada, Switzerland, Japan)
- **Direction for growth**: Launching new platform companies at a steady cadence (e.g., Terion, Serif in 2026); deepening expertise in computational protein design, modified DNA, and gene editing

## Why Work Here
- **Culture**: “Brave and bold organization of creative-thinkers with insurgent mindsets” – emphasis on fearlessness, mentorship, and teamwork across science and business
- **Work Environment**: Headquarters in Cambridge, MA with 5 US offices; roles span research, strategy, finance, and operations; hybrid/remote flexibility varies by role
- **Notable Perks**: Opportunity to work on world-changing science (e.g., COVID‑19 vaccine, gene editing) alongside top scientists and company builders; strong compensation (salary range example: Sr. Associate ~$68K, ML Engineer ~$122K; overall comp rating 3.7/5)
- **Engineering/Science Culture**: Heavy investment in R&D (15% of workforce in research), cutting-edge tools (Cryo‑EM, AI/ML), and a process that encourages bold leaps

## Sources
1. [flagshippioneering.com](https://www.flagshippioneering.com/)
2. [flagshippioneering.com/about](https://www.flagshippioneering.com/about)
3. [flagshippioneering.com/join](https://www.flagshippioneering.com/join)
4. [flagshippioneering.com/join/roles](https://www.flagshippioneering.com/join/roles)
5. [linkedin.com/company/flagship-pioneering](https://www.linkedin.com/company/flagship-pioneering)

## Other roles at Flagship Pioneering, Inc.

- [Senior Research Associate / Associate Scientist, Nonclinical](https://feeny.ai/job/senior-research-associate-associate-scientist-nonclinical-flagship-pioneering-kpyk97evc5j0) — Cambridge, MA
- [Senior Analog/Mixed-Signal Hardware Engineer, Single-Molecule Sensing Instrumentation](https://feeny.ai/job/senior-analog-mixed-signal-hardware-engineer-single-molecule-sensing-jngdq7cygjxb) — Cambridge, MA
- [FL114: Scientist, Genomics](https://feeny.ai/job/fl114-scientist-genomics-flagship-pioneering-inc-cambridge-7y7dcef63454) — Cambridge, MA
- [Sr. Scientist, Protein & Cell Sciences](https://feeny.ai/job/sr-scientist-protein-cell-sciences-flagship-pioneering-inc-somerville-ma-qpeg3dfcafh3) — Somerville MA, United States
- [Senior Director, Platform Experience](https://feeny.ai/job/senior-director-platform-experience-flagship-pioneering-inc-cambridge-cqx7ym4352dv) — Cambridge, MA
- [Principal Scientist, Structural Biology / Protein Biophysics](https://feeny.ai/job/principal-scientist-structural-biology-protein-biophysics-flagship-pioneering-hmdq4s5y31f7) — Cambridge, MA
- [Senior Scientist, LNP Formulations](https://feeny.ai/job/senior-scientist-lnp-formulations-flagship-pioneering-inc-cambridge-ztwykh5vnq98) — Cambridge, MA
- [Flagship Pioneering ML Internship](https://feeny.ai/job/flagship-pioneering-ml-internship-flagship-pioneering-inc-cambridge-dsf2d8q572m7) — Cambridge, MA
- [Research Associate II/Senior Research Associate, LNP Production](https://feeny.ai/job/research-associate-ii-senior-research-associate-lnp-production-flagship-bwk9zn8pyhy8) — Cambridge, MA
- [Senior ML Engineer](https://feeny.ai/job/senior-ml-engineer-flagship-pioneering-inc-cambridge-aexf2nmm2e1x) — Cambridge, MA