---
title: 'General Interest at PostEra'
canonical: 'https://feeny.ai/job/general-interest-postera-remote-vqge8s8xaq10'
type: 'job'
last_seen: '2026-10-18'
---

# General Interest at PostEra

- **Company:** PostEra
- **Location:** Remote
- **Employment:** full-time
- **Work type:** remote
- **Posted:** 2023-11-03
- **Last confirmed live:** 2026-10-18
- **Apply:** https://jobs.lever.co/postera/f89193c2-d755-47e9-95f3-3dc1c99f41e6

## Job description

PostEra is building an AI-first biotech. We use Proton, our AI platform for medicinal chemistry, to accelerate the discovery of new medicines for patients. PostEra is advancing an internal pipeline focused on Women's Health and Fertility, and has used Proton to nominate multiple clinical candidates across PMOS and Fertility. PostEra also advances small molecule programs through partnerships with pharma. We've closed over $1B in AI partnerships including 4 multi-year agreements with Pfizer and Amgen. PostEra is also leading an antiviral drug discovery center for pandemic preparedness, funded by one of the largest grants in NIH history. PostEra's Organizational Structure We believe time spent navigating complex hierarchies in organizations is better invested in the pursuit of novel technology and scientific discoveries. As such, our organizational structure is intentionally minimalist. We promote a culture where individual achievement is celebrated through proportional compensation and internal recognition, including meaningful promotions. Ultimately, our collective focus is delivering cures to patients, which we believe needs a huge amount of cross-disciplinary collaboration, so we've fitted our organizational structure to serve that end.

If you have an interest in joining PostEra Inc, but don't see a posted position that is a perfect fit for you, feel free to submit your information here. We'll review your submission, keep it on file, and we may reach out if a position opens that we think you might be a qualified candidate for.

All roles at PostEra are open to candidates located in the US and can be remote within the United States. We have an office in Cambridge, MA.

## Benefits

- PostEra offers comprehensive health, vision, and dental coverage as well as life insurance
- Unlimited PTO (approximately 20 days encouraged annually), plus unlimited sick leave
- 401K plans and up to 4% matching on contributions
- Generous budget for home office set up, co-working space, and weekly stipend for lunch
- Paid parental leave

Visit us at postera.ai

## About PostEra

## Company Overview
- **One-liner**: PostEra is an AI-first biopharmaceutical company using its Proton machine learning platform to accelerate medicinal chemistry and drug discovery for patients.
- **Entity Type**: Private (venture-backed; Y Combinator Winter 2020 batch)
- **Headquarters**: Cambridge, Massachusetts, USA (office also referred to as Boston, MA)
- **Founded**: 2019
- **Founders**: Aaron Morris (CEO), Alpha Lee (CSO), Matthew Robinson (CTO) — listed as active founders on Y Combinator and the PostEra team page

## Core Business
- **Primary industry**: AI-driven drug discovery / biopharmaceuticals / medicinal chemistry
- **Target customers**: B2B — large pharmaceutical companies (Pfizer, Amgen), government/public health (NIH), plus an internal drug pipeline for patients
- **Mission or purpose statement**: Use machine learning to close the Design-Make-Test cycle of medicinal chemistry, making drug discovery faster, more efficient, and ultimately delivering better medicines to patients

## Products & Services
- **Proton (AI Platform)**: End-to-end machine learning platform for medicinal chemistry. Supports all three stages of the drug discovery cycle — Design (using proprietary data + chemistry foundation models), Make (state-of-the-art synthesis and route design enabling parallel molecule production), and Test (active learning to gather the most informative data). Deployed both in internal pipelines and in pharma collaborations.
- **AI Drug Discovery Partnerships**: Multi-year collaborations with Pfizer — expanded to $610M in March 2024 — and Amgen, bringing total AI drug discovery collaborations to over $1B.
- **Internal Pipeline**: Advancing small-molecule programs focused on Women's Health and Reproductive Medicine.
- **Open Science / Pandemic Preparedness**: Creator and leader of COVID Moonshot, the world's largest open-science drug discovery initiative, and leader of a $68M antiviral drug discovery center for pandemic preparedness supported by the NIH.

## Market Standing
- **Valuation/Market Cap**: Not publicly disclosed
- **Key Metric**: Total funding of $26M raised; over $1B in AI drug discovery partnerships (Pfizer and Amgen combined)
- **Notable Investors/Partners**: Y Combinator (W2020), Pfizer, Amgen, NIH
- **Growth Signals**: Pfizer collaboration expanded to $610M (March 2024); Amgen collaboration added to reach $1B+ in AI partnerships; $68M NIH-backed antiviral center; ~40-person team per Y Combinator (with active hiring across drug discovery, ML, and engineering)

## Competitive Advantages
- **Proprietary AI platform (Proton)**: Combines proprietary experimental data with chemistry foundation models and active learning, giving a full-cycle, end-to-end advantage rather than point solutions.
- **Interpretable AI**: Explicitly emphasizes that its AI is "not a black box," building trust with regulatory/commercial pharma partners.
- **Real-world validation**: Practically proven via large, multi-year agreements with top-tier pharma (Pfizer, Amgen) and public-sector work (NIH, COVID Moonshot).
- **Open-science credibility**: Led the world's largest open-science drug discovery effort (COVID Moonshot), demonstrating ability to coordinate large-scale, mission-critical research.

## Strategic Focus
- Advancing an internal pipeline in Women's Health and Reproductive Medicine.
- Scaling AI partnerships with major pharma players (four confirmed multi-year agreements with Pfizer and Amgen).
- Continuing to improve Proton's design-make-test capabilities to shorten drug discovery timelines.
- Maintaining pandemic preparedness and open-science initiatives as a public-health differentiator.

## Why Work Here
- **Mission-driven**: Directly focused on bringing cures to patients faster through cross-disciplinary collaboration between drug hunters, researchers, and machine learning engineers.
- **Organizational philosophy**: Intentionally minimalist structure designed to reduce hierarchy and maximize time spent on science and technology; proportional compensation tied to individual achievement.
- **Remote-friendly**: All US-based roles are remote-eligible; physical office available in Cambridge, MA.
- **Benefits**: Comprehensive health, vision, and dental coverage plus life insurance; 20 days PTO and unlimited sick leave; 401K with up to 4% company match; generous budget for home office setup, co-working space, and a weekly lunch stipend; paid parental leave.

## Sources
1. [postera.ai](https://postera.ai/)
2. [postera.ai/about](https://postera.ai/about/)
3. [postera.ai/team](https://postera.ai/team/)
4. [ycombinator.com](https://www.ycombinator.com/companies/postera)
5. [jobs.lever.co](https://jobs.lever.co/postera/f89193c2-d755-47e9-95f3-3dc1c99f41e6)

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