---
title: 'Head of Commercial at Boltz'
canonical: 'https://feeny.ai/job/head-of-commercial-boltz-london-ve3f87293d6n'
type: 'job'
last_seen: '2026-09-13'
---

# Head of Commercial at Boltz

- **Company:** Boltz
- **Location:** London, United Kingdom
- **Employment:** full-time
- **Work type:** onsite
- **Posted:** 2026-08-16
- **Last confirmed live:** 2026-09-13
- **Apply:** https://jobs.gem.com/boltz/am9icG9zdDoBmiq6oC_lo6svFIxkcFF_

## Job description

## About Boltz

Boltz is a public benefit company building the next generation of AI-powered molecular modeling tools to make biology programmable and accelerate drug discovery, while keeping frontier capabilities broadly accessible.

Boltz-1, Boltz-2, and BoltzGen are open models trusted by 100,000+ scientists across biotech and academia, and used in programs at every Top 20 pharma as well as leading agrichemical and industrial research organizations.

We deliver these capabilities through Boltz Lab, our platform for running our latest models and design agents as reliable, production-grade tools. Boltz Lab is designed around real chemistry and biology workflows, so teams can start from a target and a hypothesis and quickly generate, evaluate, and rank candidate molecules.

## About the role

As Head of Commercial, you will own Boltz’s enterprise commercial motion, converting inbound interest from leading pharma and biotech organizations into large, structured platform partnerships.

Boltz already has a strong top-of-funnel driven by scientific credibility and open-source adoption. Your role is to translate that demand into $1M+ ACV enterprise contracts, deploying Boltz models into secure customer environments and structuring long-term collaborations.

You will operate as a player-coach: personally leading high-value deals while building a repeatable enterprise sales motion. This includes scoping complex engagements, negotiating contracts, and expanding key accounts over time.

You will work closely with the CEO, scientific leadership, and product to ensure that commercial engagements are grounded in real scientific value and aligned with Boltz’s long-term platform vision.

## About you

Essentials:

- 5+ years of experience in sales or business development with a proven track record closing multimillion dollar enterprise deals in frontier technology (ideally software)
- Comfortable leading sales and building sales function from scratch
- Strong technical fluency - able to engage credibly with ML, infrastructure, and product teams
- Ability to convert warm inbound demand into structured, closed deals without heavy SDR support
- Excellent communication, negotiation, and stakeholder management skills

Nice to have:

- Experience in life sciences, biotech, or pharma
- Background at companies deploying AI tools into enterprises
- Existing network across large pharma and biotech organizations
- Experience deploying products into secure or VPC environments

What we offer:

- Opportunity to define the commercial strategy of a category-defining AI platform
- Direct ownership of high-value enterprise relationships across global pharma
- Significant autonomy and influence at company level
- Highly competitive compensation with substantial equity

## About Boltz

## Company Overview
- **One-liner**: Boltz builds foundational AI models and a platform for biomolecular modeling and design, enabling scientists to engineer proteins and small molecules for drug discovery.
- **Entity Type**: Private (Seed stage; raised $28M)
- **Headquarters**: London, United Kingdom (also has an office in Boston, Massachusetts, USA)
- **Founded**: 2025
- **Founders**: Not publicly available (the company originated from research at MIT)

## Core Business
- **Primary industry/industries**: Artificial intelligence for biology and chemistry; biotechnology research
- **Target customers**: B2B – pharmaceutical companies (including all top 20 pharma), biotech startups, academic labs, and individual scientists
- **Mission or purpose statement**: To advance the frontier of AI capabilities in biology through open science and make them universally accessible to every scientist working toward a healthier, more sustainable future. Boltz is a Public Benefit Corporation (PBC).

## Products & Services
- **Boltz-1 / Boltz-1x**: Open-source structure prediction models approaching AlphaFold3-level accuracy; commercially usable under a permissive license.
- **Boltz-2**: Frontier structure prediction model that pushes binding affinity prediction to unprecedented accuracy using large-scale supervision.
- **BoltzGen**: A protein design model and agent capable of generating binders to arbitrary targets, validated across diverse modalities, targets, and assays.
- **Boltz Lab**: A cloud platform (in beta) providing hosted compute, agentic workflows for small-molecule discovery and protein design, collaborative interfaces, and enterprise deployments (multi-tenant, single-tenant, or on-premise). SOC 2 Type 1 verified. Usage-based pricing with generous free tiers.

## Market Standing
- **Valuation/Market Cap**: Not disclosed
- **Key Metric**: $28M in total seed funding (1 prior round)
- **Notable Investors/Partners**: Amplify, a16z, Zetta (co-leads); angel investors include Clement Delangue (CEO of Hugging Face), Factorial Capital, Obvious Ventures. **Key partnership**: multi-year agreement with Pfizer to deploy Boltz Lab across the company and co-develop new foundation models.
- **Growth Signals**: 5M+ downloads, 100k+ scientists using the models, adoption by all top 20 pharma companies and thousands of biotechs. Rapidly expanding team (hiring research engineers, software engineers, product designers, protein engineers).

## Competitive Advantages
- **Open‑source foundation**: Permissively licensed models (Boltz-1, Boltz-1x) that have been validated by the community, lowering the barrier to entry and building trust.
- **Performance and cost**: Claims the lowest price per unit of any major provider in the space; optimized models reduce compute costs.
- **IP protection**: Customers own their outputs, data stays secure, and Boltz does not train on customer data. Offers on-premise deployment for sensitive work.
- **Public Benefit Corporation**: Mission‑aligned structure that explicitly avoids competing with customers (Boltz does not develop drugs itself).

## Strategic Focus
- **Three pillars**: Research (understand and reprogram biology from the bottom up), Product (put powerful AI into scientists’ hands via agentic workflows and eventually autonomous labs), Community (open science and broad accessibility).
- **Current priorities**: Expanding the Boltz Lab platform, fine‑tuning models on proprietary customer data, building agents for new modalities, and scaling enterprise partnerships.

## Why Work Here
- **Culture**: Mission‑driven, open‑science ethos with a strong emphasis on research excellence and product impact. The team is lean (~17 employees as of early 2026) and growing.
- **Remote/Hybrid**: Not explicitly stated; locations include London (HQ) and Boston. Likely flexible given the global team (employees in UK, US, Netherlands, Switzerland).
- **Notable perks**: Opportunity to work on frontier AI models used by 100k+ scientists; direct collaboration with top pharma; usage‑based pricing aligns with customer success; public‑benefit status ensures long‑term mission alignment.
- **Engineering culture**: Heavy focus on research engineering, software engineering, and product design. Looking for protein engineers with preclinical experience to shape the product roadmap.

## Sources
1. [boltz.bio](https://boltz.bio/)
2. [boltz.bio/manifesto](https://boltz.bio/manifesto)
3. [boltz.bio/launch](https://boltz.bio/launch)
4. [linkedin.com/company/boltz-bio](https://linkedin.com/company/boltz-bio)
5. [cbinsights.com/company/boltz](https://www.cbinsights.com/company/boltz)

## Other roles at Boltz

- [Head of Partnerships & Developer Relations](https://feeny.ai/job/head-of-partnerships-developer-relations-boltz-london-081mbxkz1s8j) — London, United Kingdom
- [Head of Community & Growth Marketing](https://feeny.ai/job/head-of-community-growth-marketing-boltz-london-qg7fj0at6fck) — London, United Kingdom
- [Community Lead](https://feeny.ai/job/community-lead-boltz-london-jgcrvj9gp234) — London, United Kingdom
- [Chief of Staff](https://feeny.ai/job/chief-of-staff-boltz-london-6c3rp0gwc86d) — London, United Kingdom
- [ADME/DMPK Scientist](https://feeny.ai/job/adme-dmpk-scientist-boltz-london-2kbrygkxpkqa) — London, United Kingdom
- [Computational Biologist](https://feeny.ai/job/computational-biologist-boltz-london-ywq0h6gna1qr) — London, United Kingdom
- [Small Molecule Computational Scientist](https://feeny.ai/job/small-molecule-computational-scientist-boltz-london-j7jz1gjm25xq) — London, United Kingdom
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- [Product Designer](https://feeny.ai/job/product-designer-boltz-london-c47gnt2jtexf) — London, United Kingdom
- [Software Engineer, Product](https://feeny.ai/job/software-engineer-product-boltz-london-ahzffabh70an) — London, United Kingdom