--- title: 'Infrastructure Architect at Epistemix' canonical: 'https://feeny.ai/job/infrastructure-architect-epistemix-united-states-rrkq2tbah3s0' type: 'job' last_seen: '2026-09-12' --- # Infrastructure Architect at Epistemix - **Company:** Epistemix - **Location:** United States - **Employment:** full-time - **Work type:** remote - **Posted:** 2025-12-22 - **Last confirmed live:** 2026-09-12 - **Apply:** https://jobs.ashbyhq.com/epistemix/40066a72-c6e7-4741-99f4-606ab38145a4 ## Job description Our Infrastructure Architect serves as the critical technical expert responsible for all post-sales deployment and integration of the Epistemix platform into client infrastructure. This is a highly technical, hands-on role. You will be the vital link between our product's architecture and our clients' varied technical landscapes. This role requires the ability to be both a hands-on architect and navigating complex client IT, security, and application environments (AWS, GCP, private cloud, or on-prem) to successfully deploy our product and ensure immediate value realization. ## About Epistemix The most consequential decisions in public health, life sciences, insurance, and enterprise strategy share a common problem: they involve human behavior, network effects, and downstream effects that cannot be safely tested before action is taken. Traditional analytical techniques built on historical data were not built for this. Epistemix was. We build simulation and data-driven modeling tools that let leaders visualize how strategies will unfold across populations and systems before they commit resources. By clarifying which variables drive outcomes, where leverage exists, and how they interact, we help organizations move from uncertainty to conviction. Getting these decisions right means faster interventions, better-allocated resources, and measurable improvements in human and economic outcomes. We exist to make that possible. Our platform gives organizations access to realistic, high-resolution population data and the modeling infrastructure to run scenario planning at scale. Together, these capabilities let decision-makers stress-test strategies in a controlled environment before deploying them in the real world across healthcare, consumer industries, insurance, and government. We are approaching our Series B and actively building the team that will define what comes next. ## Responsibilities - Design and execute the technical strategy for integrating the Epistemix platform into client environments. - Leverage Terraform, Kubernetes and Docker across client environments, ensuring security and repeatability with a primary focus on AWS and data connections like Snowflake and Databricks. - Interface with client IT organization to understand infrastructure environment and provide architectural guidance during implementation. - Ensure all client-side integration and deployment methods are designed to meet rigorous standards, including SOC 2 and ISO 27001, HIPAA. - Work with client IT organizations to set deployments in complex settings, including public cloud (AWS/GCP), private cloud, and traditional on-premises/dedicated application environments. - Develop and use custom automation tooling (Python is a must) to streamline deployment processes, integrating with client-side identity and access management (e.g., OAuth2/OIDC). ## Qualifications - 8+ years of industry experience, 3+ years of architectural implementation experience - Hands on and expert level experience in: - Python, Fast API and/or Django - Terraform. Additional knowledge of Kubernetes, and Docker highly preferred. - AWS infrastructure. General architectural mastery of another major cloud provider (GCP) is highly valued. - Bachelors Degree in Computer Science or a relevant technical discipline such as Mathematics, Statistics, Epidemiology, or Public Health - Demonstrated experience managing or contributing to organizational compliance programs, specifically the development and implementation of policies and procedures related to HIPAA (HITECH Act) privacy/security rules and achieving SOC 2 attestation - Experience with data warehouse integrations with Snowflake, Databricks or other data warehouse platforms. - Experience managing and supporting deployments in environments beyond public cloud (e.g., on-premise, private cloud, or dedicated client application environments). ## Nice to Have Experience - Familiarity with the architectural demands of distributed computing libraries (Ray, Modin, Pandas) is highly valued. - Familiarity with JavaScript/TypeScript, Node.js, and React. - Familiarity with leveraging generative AI tools in engineering workflows (e.g., Claude Code, Devin, Coderabbit). Why Join Epistemix? By joining Epistemix, you will become part of a collaborative and rapidly growing team that values curiosity and creativity. We are fully remote, with team members in the United States and Europe. Benefits include: - Equity & Incentives – Participation in our stock option program. - Flexible Time Off – Autonomy to manage your schedule and work-life balance. - Health, Welfare and 401(k) Programs – Eligibility for benefits (for U.S. employees). - Meaningful Impact – Apply your creative talents to revolutionize data-driven decision-making and make a real-world difference. This is a remote position open to applicants located in the United States. Candidates must possess the legal right to work in their intended work location, as we are currently unable to sponsor or transfer employment visas for any country, including the United States. ## About Epistemix ## Company Overview - **One-liner**: Epistemix provides an agent-based simulation platform that enables organizations to forecast population behavior, manage risk, and make data-driven decisions in low-information environments. - **Entity Type**: Private (Post-Series A; raised $19.5M in total funding across 7 rounds) - **Headquarters**: Pittsburgh, Pennsylvania, United States (with an office in the United Kingdom) - **Founded**: 2018 - **Founders**: John Cordier (CEO) ## Core Business - **Primary industry/industries**: Simulation Software, Population Modeling, Decision Intelligence, Public Health - **Target customers**: Government agencies (public health), Global Corporations (CPG, healthcare, finance), and Research Organizations (B2B, Enterprise) - **Mission or purpose statement**: Epistemix is building the tools to make sense of complex population dynamics to empower better decisions — replacing uncertainty with clarity and moving decision-making from guesswork to insight. ## Products & Services - **[Populus]**: A population data platform that provides a statistically representative 1:1 synthetic population of a target market. Used for sizing Total Addressable Market (TAM), segmenting audiences, enriching existing data, and discovering patterns traditional analyses miss. (Data/API Platform) - **[Polaris]**: A scenario planning platform that empowers organizations to test strategies, optimize decisions, and shorten decision cycles through simulation, AI, and inference. Users can ask "What If...?" to understand the impact of different scenarios (e.g., product launches, resource allocation, health benefit adoption). (SaaS Simulation Platform) - **Custom Consulting / Modeling Services**: Epistemix partners with clients to build bespoke agent-based models for specific strategic challenges (e.g., disease spread, market saturation, political polarization). (Service) ## Market Standing - **Total Funding**: $19.5M (across 7 rounds) - **Latest Round (Seed/Series A mix)**: - Series A (2024-03-31): $5.0M from 3 investors - Venture Round (2022-02-11): $5.1M - Seed Round (2022-03-01): $5.0M from 4 investors - **Notable Investors/Partners**: Not fully disclosed in public sources, but seed/Series A syndicate includes multiple unnamed institutional investors. Partners include leading public health agencies and global corporations. - **Growth Signals**: - Headcount grew 15% YoY (16 employees as of mid-2025). - LinkedIn followers grew 30.2% over the past year. - Website traffic grew 281.6% year-over-year. - Actively hiring with 14 open positions (including AI Engineers, Data Scientists, and Backend Engineers). - Clients include major public health agencies and global CPG/healthcare firms. ## Competitive Advantages - **Proprietary Synthetic Population Technology**: Epistemix builds statistically representative "digital twins" of entire populations (countries, cities, target demographics) without using real PII. This allows them to model behavior in environments where traditional data is sparse or unavailable. - **Agent-Based Modeling (ABM) at Scale**: Unlike traditional statistical models, their ABM simulates the interactions of millions of individual "agents," capturing emergent behaviors (e.g., tipping points, market saturation, cultural movements) that aggregate models miss. - **Academic-to-Commercial Bridge**: Born from academic research, the platform has been validated in high-stakes environments (e.g., pandemic response), providing a strong credibility moat. - **High Switching Costs**: The platform integrates deeply into client planning workflows. Once an organization builds its decision-making process around Epistemix’s simulation outputs, the cost and risk of switching to a less sophisticated alternative are high. ## Strategic Focus - **Product-Led Growth & Platformization**: Shifting from bespoke consulting to a self-service and scalable SaaS platform (Populus/Polaris). - **Industry Expansion**: Moving beyond public health into CPG, financial services, and climate resilience. - **AI Integration**: Leveraging AI and inference engines within the platform to accelerate scenario creation and improve prediction accuracy. - **Talent Acquisition**: Bulking up engineering and data science teams (hiring for AI Engineers, Synthetic Population Engineers, and Senior Backend Engineers) to accelerate product development. ## Why Work Here - **Mission-Driven**: Work on the "biggest challenges of our time" — pandemics, climate change, political polarization — by giving leaders the tools to make sense of complex dynamics. - **Culture & Values**: Guided by values of **Empathy** (understanding users, constraints, motivations), **Clarity** (keeping things simple, being forthright), **Inspiration** ("checkers, not chess" — focus on long-term strategy), and **Grit** (sustained effort to win). - **Technical Depth**: Strong emphasis on agent-based modeling, synthetic populations, and AI. Tech stack includes Python, TypeScript, Django, React, Postgres, Kubernetes, AWS, Terraform, and modern CI/CD tooling. - **Growth Opportunity**: As a 16-person company growing rapidly (15% YoY headcount growth) with $19.5M in funding, new hires have significant ownership and impact over product direction. - **Work Modes**: Primarily in-office presence (HQ in Pittsburgh, PA) with some flexible arrangements. The team culture emphasizes direct collaboration on complex modeling challenges. ## Sources 1. [epistemix.com](https://epistemix.com/) 2. [epistemix.com (About)](https://epistemix.com/about) 3. [epistemix.com (Careers)](https://epistemix.com/careers) 4. [LinkedIn Company Page](https://www.linkedin.com/company/epistemix) 5. [Ashby Job Board](https://jobs.ashbyhq.com/epistemix) 6. [Wellfound (AngelList) - Epistemix](https://wellfound.com/company/epistemix) ## Other roles at Epistemix - [Manager, Strategic Operations](https://feeny.ai/job/manager-strategic-operations-epistemix-united-states-mdmr3gxg5z73) — United States - [Data Scientist](https://feeny.ai/job/data-scientist-epistemix-united-states-ghye54d22xmh) — United States - [AI Engineer](https://feeny.ai/job/ai-engineer-epistemix-united-states-dpxypqt55x7z) — United States - [Synthetic Population Engineer](https://feeny.ai/job/synthetic-population-engineer-epistemix-united-states-gj0qtws52gg1) — United States - [Senior Back End Software Engineer](https://feeny.ai/job/senior-back-end-software-engineer-epistemix-united-states-xf60zc9ynjeh) — United States - [Infrastructure Architect](https://feeny.ai/job/infrastructure-architect-lts-united-states-558cs2g2sq2q) — United States - [Infrastructure Architect](https://feeny.ai/job/infrastructure-architect-eq-bank-canada-s-challenger-bank-toronto-esvww8q9rps8) — Toronto, Canada