--- title: 'Infrastructure Software Engineer (AI Enablement) at LatchBio' canonical: 'https://feeny.ai/job/infrastructure-software-engineer-ai-enablement-latchbio-san-francisco-11xqfy5rmwkt' type: 'job' last_seen: '2026-10-20' --- # Infrastructure Software Engineer (AI Enablement) at LatchBio - **Company:** LatchBio - **Location:** San Francisco, CA - **Employment:** full-time - **Work type:** onsite - **Posted:** 2026-10-13 - **Last confirmed live:** 2026-10-20 - **Apply:** https://jobs.ashbyhq.com/latchbio/57fcf84e-36c3-4684-9a80-9d96661b096e ## Job description Infrastructure Engineer (AI Enablement) Our mission is to advance humanity's ability to engineer biology. We approach this by understanding and improving AI's application to biology use cases such as therapeutics and biosecurity. We are a group of engineers, scientists, and operations specialists who are driven by improving capabilities and interpretability. Some of our work is showcased on [benchmarks.bio](http://benchmarks.bio) What you'll do. - You will be working on problems including agent infrastructure and orchestration, ML infrastructure, model benchmarking at scale, full stack web development, developer and user experience, and process optimization. Infrastructure challenges span container orchestration, sandboxing, distributed filesystems, cloud architecture, and database systems. - Your particular area of ownership will be developer experience and ops. You should expect this to take up less than 50% of your engineering time to start but be an area of passion and focus for you. You should be a strong overall engineer who has a knack for improving the productivity of those around you through tools and systems, particularly ones that tradeoff LLM tokens to get human time back. What you bring. - AI-native engineer. You use AI coding agents every day and have built tooling, workflows, or integrations that made them more effective for a whole team, not just yourself. - Strong software engineering. 3+ years writing production code in Python, Go, or TypeScript. You can get productive in an unfamiliar codebase fast. - Developer tools builder. You’ve built internal tools or developer-experience improvements that other engineers actually adopted. - DevOps fluency. Hands-on experience with CI/CD, AWS or GCP, Docker, and infrastructure-as-code. You don’t need to be a career SRE, but you can own the pipeline. - Teacher and evangelist. You can show engineers a better way to work and get them to adopt it through demos, docs, and pairing rather than mandates. How we work. This position is based in our San Francisco office; you'll work closely with science, partnerships, ops, and engineering. We have two key meetings each week, plus ad hoc ones as needed. The work is busy, and the schedule is flexible. We don't track when you're online, and PTO is unlimited. What matters is that projects ship well and on time, or early. Culture. We believe in radical transparency: you'll know how the company is doing, what's working, and what isn't. It's always us against the problem, never each other. We're opinionated but respectful, and we bring solutions along with the problems. Come in at the time that works for you; just let the team know via slack if you'll be later than usual. We keep meetings to a minimum and judge people on innovation and output, not hours. Outside of work, we have company outings most months, team off-sites, latch run club, cycling, boxing, ice skating, and playing soccer together; feel free to add to the list. ## Benefits - Base Salary ($170k- $250k) - Performance Bonus - Great Equity - Unlimited PTO - Every lunch and dinner is paid for - 100% premium covered on Cigna's platinum health plan ($0 premium, $0 deductible) and 50% premium coverage for dependents. 100% coverage for top-tier Guardian dental and vision plans - We sponsor most work visas - Relocation Assistance - 401(k) Plan - Company-Sponsored professional development Who you'll work with most - Founders: Alfredo, Kyle, Kenny - Chief Product Officer: Hannah - Operations: Jordan, Daniel, Saul, Andy, Charles, Jesse, Camila - MTS: Zhen, Harmon, Chris, Dillon, Martin, Ramesh, Ian, Evan, John - Scientists across Latch Learn more about us - [About Us](https://latch.bio/about) · [Website](https://latch.bio/) · [Twitter](https://x.com/LatchBio?lang=en) · [Blog](https://blog.latch.bio/) How to apply Our process moves quickly. - Round 0 - Apply - Round 1 - Technical Interview with Head of Engineering - Round 2 - Take home Technical Assessment - Round 3 - On-site work-trial with Latch Team (2-3 days) - Offer ## About LatchBio ## Company Overview - **One-liner**: LatchBio builds and deploys frontier AI agents for biological data analysis, serving over 300 biopharma and R&D labs worldwide. - **Entity Type**: Private (Series A; total funding $33.2M) - **Headquarters**: San Francisco, California, United States - **Founded**: 2021 - **Founders**: Alfredo Andere (CEO) and Kenny Workman (CTO) ## Core Business - Primary industry: Biotechnology Research / AI for biology - Target customers: B2B – biopharma companies, academic R&D labs, and solution providers (kits, assays, instrument vendors) - Mission: Deploy AI agents into real scientific work to accelerate data analysis and drug discovery ## Products & Services - **Latch Platform**: A unified, serverless bioinformatics platform that lets scientists run, track, and debug pipelines via an SDK-generated no-code interface. Supports FastQ, CSV, H5AD, TIFF, and other formats. Agents can analyze messy real-world data. - **Latch SDK**: Python toolchain to define serverless workflows and dynamically generate no-code UIs, removing cloud-infrastructure overhead. - **agent.bio**: Public, interactive sandbox where frontier AI agents (e.g., Claude 4.8 Opus) analyze biological data. Supports 40+ solution providers. - **benchmarks.bio**: Open, reproducible benchmarks measuring AI agent performance on spatial, single-cell, epigenomics, and preclinical pharmacology data. Includes papers like scBench-Long, TxBench-PP, etc. - **White-labeled data analysis**: Solution providers can offer a branded, simpler analysis experience for their kits and services. ## Market Standing - **Valuation/Market Cap**: Not publicly disclosed - **Key Metric**: Annual revenue of ~$1.0M (LinkedIn estimate); total funding $33.2M - **Notable Investors/Partners**: Coatue, Lux Capital, Fifty Years, Haystack, Gelt, Backend Capital; individual investors include George Church, Jeff Dean, Hemant Taneja, Laura Deming, Alec Nielsen - **Growth Signals**: 140% YoY headcount growth (from ~11 to 26 employees); 300+ biopharma and academic teams served; 40+ solution providers onboarded; recent publication of multiple benchmark papers (2025–2026) ## Competitive Advantages - **First-mover in AI agents for biology**: Combines frontier LLMs with rigorous, verifiable benchmarks tailored to biological data (spatial, single-cell, epigenomics, pharmacology). - **Open benchmarks & reproducibility**: All benchmarks (e.g., scBench-Long) are published openly, building trust and attracting top talent. - **White-labeling for solution providers**: Allows kit and instrument vendors to offer AI-powered data analysis under their own brand, creating a network effect. - **Tight integration with real lab workflows**: Supports common file formats and interfaces with existing pipelines, reducing friction for scientists. ## Strategic Focus - Continue research and deployment of AI agents for biology, with emphasis on long-horizon tasks and messy real-world data. - Expand the agent.bio sandbox to more solution providers and biopharma customers. - Publish additional benchmarks (spatial, preclinical) to establish Latch as the standard evaluator of AI in biology. - Grow engineering and bioinformatics teams to accelerate platform development. ## Why Work Here - **Engineering culture**: Small, high-autonomy team where engineers own features end-to-end and see their code impact thousands of scientists the same day. Reading groups on category theory, immunology, and more. - **Remote/hybrid policy**: Not explicitly stated, but headquarters in San Francisco; office parking subsidized. Likely in-office with flexibility. - **Notable perks**: Unlimited PTO, 100%-subsidized platinum health plan (Cigna) + 75% for dependents, dental/vision, 401(k), ambitious equity, 12+ meals weekly, annual tech stipend, signing bonus, O-1 visa sponsorship, professional development. - **Team size**: ~26 employees, with 65% in technical roles (engineering, bioinformatics, research). Flat structure with direct access to founders. - **Growth trajectory**: Rapid headcount growth and expanding customer base offer career acceleration opportunities. ## Sources 1. [latch.bio](https://latch.bio/) 2. [latch.bio/about](https://latch.bio/about) 3. [linkedin.com/company/latchbio](https://www.linkedin.com/company/latchbio) 4. [cbinsights.com/company/latch-bio](https://www.cbinsights.com/company/latch-bio) 5. [jobs.ashbyhq.com/latchbio](https://jobs.ashbyhq.com/latchbio) ## Other roles at LatchBio - [AI Biologist - Biologics Development](https://feeny.ai/job/ai-biologist-biologics-development-latchbio-san-francisco-35ags5d0ggjd) — San Francisco, CA - [AI Biologist - Microscopy](https://feeny.ai/job/ai-biologist-microscopy-latchbio-san-francisco-9jjczg715v57) — San Francisco, CA - [Bioengineer, Lead Scientist](https://feeny.ai/job/bioengineer-lead-scientist-latchbio-san-francisco-ncn4k93pda7h) — San Francisco, CA - [Member of Technical Staff, Science](https://feeny.ai/job/member-of-technical-staff-science-latchbio-san-francisco-fa8cmn24ejsq) — San Francisco, CA - [Product Manager](https://feeny.ai/job/product-manager-latchbio-san-francisco-5x4se0850mbq) — San Francisco, CA - [Production Manager](https://feeny.ai/job/production-manager-latchbio-san-francisco-fp1wahrzs1tx) — San Francisco, CA - [AI Neuroscientist](https://feeny.ai/job/ai-neuroscientist-latchbio-san-francisco-9zp5zbsy4dty) — San Francisco, CA - [Technical Ops & Enablement](https://feeny.ai/job/technical-ops-enablement-latchbio-san-francisco-v5m3w6r50g1h) — San Francisco, CA - [Operations Generalist](https://feeny.ai/job/operations-generalist-latchbio-san-francisco-1gx68ftmfx7p) — San Francisco, CA - [Workplace & Community Lead](https://feeny.ai/job/workplace-community-lead-latchbio-san-francisco-22q7svm32qrg) — San Francisco, CA