---
title: 'IT & Security Lead at NewLimit'
canonical: 'https://feeny.ai/job/it-security-lead-newlimit-south-san-francisco-zdar0wnmwbkn'
type: 'job'
last_seen: '2026-09-11'
---

# IT & Security Lead at NewLimit

- **Company:** NewLimit
- **Location:** South San Francisco, CA
- **Posted:** 2026-07-01
- **Last confirmed live:** 2026-09-11
- **Apply:** https://job-boards.greenhouse.io/newlimit/jobs/6105440004

## Job description

## About NewLimit

NewLimit is a biotechnology company working to radically extend human healthspan. We're developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism to restore regenerative potential in aged and diseased cells. We leverage functional genomics, pooled perturbation screening, and machine learning models to unravel the biology of epigenetic aging and disease using experiments of unprecedented scale.

Position

We're hiring our first dedicated IT lead to own the systems, infrastructure, and security that keep NewLimit running as we grow from to more than 100 people over the next two years. This is a hands-on individual contributor role with broad ownership: you’ll set technical direction, decide what we build, buy, automate, or outsource, and jump in yourself when that’s the fastest path. An MSP handles routine helpdesk, provisioning, and onboarding/offboarding, so you can focus on the most critical strategic work that requires judgment.

Your scope will span identity and access, endpoints, office and lab infrastructure, security, SaaS systems, and a shared stake in cloud and data infrastructure. You’ll help us scale these systems as we enter first-in-human studies and expand clinical, manufacturing, and sponsor-facing operations—raising the bar on security, reliability, data integrity, and audit readiness without burying a fast-moving biotech in process.

We care more about slope than intercept. You’ve owned real systems, learn unfamiliar domains quickly, and would rather automate a recurring problem than file another ticket. You’ll sit within Computational Sciences alongside computational biologists and software and ML engineers who will help with hard problems and expect the same from you.

## What you’ll do

- Own identity, access, and endpoint standards across Google Workspace, AWS, GitHub, and our macOS/Windows fleet: least privilege, phishing-resistant MFA, SSO, device compliance, and lifecycle automation.
- Lead our MSP and technical vendor relationships day to day: scope, SLAs, escalations, renewals, and performance. Help decide what we build, buy, outsource, or bring in-house.
- Run security operations at our scale, including monitoring, incident response, tabletop exercises, and post-incident reviews, working with MDR/IR partners where they add leverage.
- Own network and office/lab infrastructure (connectivity, backups, continuity), and partner with the team on cloud and data infrastructure: AWS account structure and security and integrations between systems (lab instruments, HRIS, finance, ELN/LIMS).
- Help build the tooling and policies that make all of this scale: onboarding and access-review automation, security reporting, LLM/agent governance, data classification, software approval, and acceptable-use standards.

## Requirements

- 4+ years in IT, infrastructure, or security, including experience as a primary or sole IT/security owner at a small company and managing MSPs or technical vendors.
- Working fluency across identity, MDM, networking, AWS fundamentals, Google Workspace or M365 administration, backups, and SaaS administration.
- You script well enough to automate your own work, move data between systems, and comfortably read someone else’s code.
- Strong practical security judgment: you know how to right-size controls for company stage and how expectations change as sponsors, auditors, and regulated workflows enter the picture.
- You already use LLMs and agents to work more effectively, understand how to use them safely, and communicate clearly with scientists, executives, vendors, and auditors.

Nice to haves

- Exposure to GxP, clinical, or other regulated environments, or SOC 2 / ISO 27001 readiness.
- Familiarity with regulated-data expectations (e.g., audit trails, ALCOA+).
- Data engineering experience: pipelines, ETL/ELT, warehouse fundamentals.
- Experience supporting lab environments where instruments, data movement, and uptime matter.

## Benefits

- Health, dental, and vision insurance
- 401(k) with company match
- Industry-leading paid time off (PTO), 20 days/year for all employees plus holidays
- Paid parental leave
- Meals and snacks on-site

Salary Range: $160,000 to $220,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. NewLimit offers a competitive benefits package, which includes a 401k, healthcare coverage, and 20 days of PTO. Learn more at: https://www.newlimit.com/careers   *This compensation and benefits information is based on Company's good faith estimate as of the date of publication and may be modified in the future.

## About NewLimit

## Company Overview
- **One-liner**: NewLimit is a biotechnology company developing epigenetic reprogramming medicines to radically extend human healthspan by reversing cellular aging.
- **Entity Type**: Private (Series B)
- **Headquarters**: South San Francisco, California, United States
- **Founded**: 2022
- **Founders**: Jacob Kimmel (Co-founder & President), Brian Armstrong (Co-founder), Blake Byers (Co-founder)

## Core Business
- **Primary industry/industries**: Biotechnology, Epigenetic Reprogramming, Longevity Therapeutics, Drug Discovery
- **Target customers**: B2B (pharmaceutical partners, clinical development), B2C (ultimately patients with age-related diseases)
- **Mission or purpose statement**: To radically extend human healthspan by creating the first medicines that reverse cellular aging at the epigenetic level.

## Products & Services
- **Discovery Engine**: An AI-powered platform that designs epigenetic payloads to make old cells look and act young. It tests thousands of designs simultaneously using genomics and retrains models iteratively on new data.
- **Therapeutics (Pipeline)**: Medicines focused on restoring youthful function in the liver, immune system, and vasculature. Initial programs target diseases resembling accelerated aging, with the goal of restoring youthful metabolism, energy levels, resilience to disease, and cognition.

## Market Standing
- **Valuation/Market Cap**: Not publicly disclosed
- **Key Metric**: Total Funding of **$215M** (across three rounds); Annual Revenue estimated at **$12.8M** [linkedin.com](https://linkedin.com/company/newlimit)
- **Notable Investors/Partners**: Kleiner Perkins (led Series B), Valor Equity Partners, Quiet Capital, S32, Duke University Management Company, Liberty Mutual Investments, Fred Ehrsam, Elad Gil, Joe Lonsdale, Eric Schmidt, Garry Tan, Brian Armstrong, Blake Byers [newlimit.com](https://www.newlimit.com/company)
- **Growth Signals**: 44 employees (+40.5% YoY), 12 active job postings (+100% YoY), LinkedIn followers grew 157.6% in the past year, and the company closed a $130M Series B in May 2025 led by Kleiner Perkins [linkedin.com](https://linkedin.com/company/newlimit).

## Competitive Advantages
- **Proprietary AI Platform**: A frontier intelligence system that designs, tests, and retrains models on epigenetic reprogramming at unprecedented scale.
- **Scientific Moats**: Deep expertise in epigenetic reprogramming (a validated but complex mechanism for reversing cellular age); a team with backgrounds from Calico, UCSF, and Stanford.
- **Founding Team & Backing**: Co-founded by Brian Armstrong (CEO of Coinbase) and Blake Byers (early investor in OpenAI, Anthropic, Neuralink), providing deep capital access and a culture of ambitious, long-term execution.

## Strategic Focus
- **Current priorities**: Advancing pipeline programs into the clinic (Head of Clinical Development role is open); scaling the Discovery Engine; building the team across computational biology, immunology, and manufacturing.
- **Direction for growth**: Transition from a discovery-stage R&D company to a clinical-stage therapeutics company; generating large revenue streams to fund the mission; expanding into new cell types and disease areas.

## Why Work Here
- **Culture**: "Not for the faint of heart" — a high-performance, mission-focused team. No pure management roles; everyone executes. Values include safety then speed, clear communication, inherent optimism, independent thinking, and top talent in every seat [newlimit.com](https://www.newlimit.com/careers).
- **Remote/Hybrid/Office**: Likely on-site/hybrid given the lab-based nature of the work (headquarters in South San Francisco).
- **Notable Perks**: Competitive salaries, comprehensive health benefits (medical, dental, vision), equity packages, 401(k) with up to 4% match, generous parental leave, 20 days PTO + 15 holidays, free EV charging [newlimit.com](https://www.newlimit.com/careers).
- **Engineering Culture**: Strong emphasis on computational biology, machine learning, and functional genomics. The team spans both wet-lab and dry-lab disciplines, with a focus on building scalable methods and iterative data-driven discovery.

## Sources
1. [NewLimit Website](https://www.newlimit.com/)
2. [NewLimit Careers Page](https://www.newlimit.com/careers)
3. [NewLimit Company Page](https://www.newlimit.com/company)
4. [NewLimit Team Page](https://www.newlimit.com/team)
5. [NewLimit LinkedIn Page](https://www.linkedin.com/company/newlimit)

## Other roles at NewLimit

- [Senior Scientist / Scientist, In Vivo Pharmacology](https://feeny.ai/job/senior-scientist-scientist-in-vivo-pharmacology-newlimit-south-san-francisco-t4a3w08ps5rd) — South San Francisco, CA
- [Senior Manager, Lab Operations](https://feeny.ai/job/senior-manager-lab-operations-newlimit-south-san-francisco-2s9yfb1zrv9n) — South San Francisco, CA
- [Scientist, LNP-Lipid Chemistry](https://feeny.ai/job/scientist-lnp-lipid-chemistry-newlimit-south-san-francisco-dhqb4z5sh4rw) — South San Francisco, CA
- [Scientist, LNP-Drug Product Development](https://feeny.ai/job/scientist-lnp-drug-product-development-newlimit-south-san-francisco-nyvhkqvmdezz) — South San Francisco, CA
- [VP/Senior Director, Clinical Operations](https://feeny.ai/job/vp-senior-director-clinical-operations-newlimit-south-san-francisco-3myq4z294a7c) — South San Francisco, CA
- [Laboratory Operations Specialist](https://feeny.ai/job/laboratory-operations-specialist-newlimit-south-san-francisco-mf010pr8xwk8) — South San Francisco, CA
- [Executive Recruiter](https://feeny.ai/job/executive-recruiter-newlimit-south-san-francisco-gyv2et7crq90) — South San Francisco, CA
- [Executive Assistant](https://feeny.ai/job/executive-assistant-newlimit-south-san-francisco-jznmrqh4wrvw) — South San Francisco, CA
- [Senior/Research Associate, Functional Genomics](https://feeny.ai/job/senior-research-associate-functional-genomics-newlimit-south-san-francisco-09h6rva4fp46) — South San Francisco, CA
- [Scientist, Drug Product Analytical](https://feeny.ai/job/scientist-drug-product-analytical-newlimit-south-san-francisco-x377jpajt45d) — South San Francisco, CA