---
title: 'Lab Director at Valius Sciences'
canonical: 'https://feeny.ai/job/lab-director-valius-sciences-boston-ckn88ysydwg4'
type: 'job'
last_seen: '2026-09-16'
---

# Lab Director at Valius Sciences

- **Company:** Valius Sciences
- **Location:** Boston, MA
- **Compensation:** $200k–$300k
- **Employment:** full-time
- **Work type:** onsite
- **Posted:** 2026-09-11
- **Last confirmed live:** 2026-09-16
- **Apply:** https://jobs.ashbyhq.com/valiussciences/585ac074-91de-4af6-bf5e-ebbbc6717b27

## Job description

Valius overview At Valius, we believe that the future of cancer care will be defined by “maximalist” diagnostics: deep, comprehensive assessments of DNA, RNA, and protein designed to give patients and their care teams the best possible understanding of how their tumor works and what its vulnerabilities are.

We’re building the diagnostics and bioinformatics company to power this future, starting by applying this approach to patients with challenging cancers. In our first year, we worked with over 75 of these patients and, in many cases, identified plausible therapeutic targets which had not been discovered previously. This coming year, we’re on track to scale our patient volume significantly, all while bringing new diagnostic modalities (e.g., single-cell transcriptomics) and analytical approaches into clinical care for the very first time.

We’ve just raised a $13.5M seed round, led by 8VC and Basis Set Ventures, and are looking for people passionate about changing cancer care to join our growing team.

Lab Director role We're hiring a Lab Director to join our team in Boston to lead the buildout and operation of Valius’s first lab. You’ll own the strategy and day-to-day operations end-to-end, including finding the right space, procuring the relevant equipment, hiring and supervising the lab talent, and overseeing the development and validation of our spatial/single-cell transcriptomic assays (using 10x Genomics instruments).

This is a rare opportunity to build a new capability from scratch in a mission-driven, high-ownership environment.

This is an in-person role in Boston.

## What you’ll do

Lab design and buildout

- Lead the design, buildout, and commissioning of Valius’s laboratory, from physical space planning through instrument installation and workflow validation
- Define lab infrastructure requirements including equipment, consumables, LIMS, and workflow automation to support clinical-grade reproducibility and scale
- Establish and document standard operating procedures (SOPs) and training programs from the ground up

Laboratory operations

- Direct day-to-day clinical lab operations, ensuring timely, accurate, and compliant processing of patient samples and reporting of results
- Oversee development and validation of complex molecular assays, including 10x Genomics spatial/single-cell RNA sequencing
- Manage technical transfer of assays from R&D into clinical operations
- Implement metrics for assay performance, turnaround time, and quality

## Team and cross-functional leadership

- Recruit, train, and lead a team of clinical laboratory scientists, supervisors, and technologists
- Collaborate closely with computational biologists and translational scientists to integrate lab outputs into patient-facing reports
- Partner with bioinformatics and operations teams to ensure data integrity and compliant reporting of high-complexity results
- Contribute to scientific and operational strategy as a senior leader within Valius

## What you’ll bring

- Advanced degree (PhD, MD, or MD/PhD) in a relevant scientific discipline (molecular biology, genomics, clinical laboratory science, or related field)
- Minimum 8-10 years of experience in clinical laboratory operations
- Proven track record of successfully establishing or scaling a molecular or clinical lab
- Experience overseeing the development of advanced molecular diagnostic assays such as bulk RNA sequencing, whole exome sequencing, and/or spatial/single-cell RNA sequencing using a 10x Genomics platform
- Strong ability to recruit, develop, and retain scientific staff
- Excellent written and verbal communication skills; ability to translate complex laboratory data into clear, actionable information for clinical, scientific, and executive stakeholders
- Commitment to our patient-focused mission
- Interest in working for a small, early-stage startup

## What we’ll bring

- Competitive salary and equity compensation
- Generous refresh grants
- Comprehensive benefits (health, dental, vision, 401(k))
- Genuine investment in your professional development
- Fun, mission-driven team culture

## About Valius Sciences

## Company Overview
- **One-liner**: Valius Sciences provides maximalist molecular diagnostic testing for cancer patients, mapping tumors across DNA, RNA, and protein layers to identify actionable therapeutic targets.
- **Entity Type**: Private (Seed/Series A – conflicting reports)
- **Headquarters**: San Francisco, United States
- **Founded**: 2025
- **Founders**: Edward Larkin, Claire Oldfield (COO), Sarah Hesse (Head of Translational Science)

## Core Business
- Primary industry/industries: Cancer diagnostics, precision oncology, molecular testing
- Target customers: B2C (cancer patients, especially those with rare, aggressive, or treatment-resistant cancers) and B2B (oncologists and care teams)
- Mission or purpose statement: To give every cancer patient — particularly those facing rare, aggressive, or treatment-resistant disease — access to the most comprehensive molecular understanding of their tumor and available treatments.

## Products & Services
- **Valius Maximalist Diagnostics Platform**: A comprehensive testing battery that includes whole genome sequencing, whole transcriptome (RNA) sequencing, single-cell RNA sequencing, spatial transcriptomics, high-plex protein staining (IHC), and ultra-sensitive ctDNA monitoring. The service identifies mutations, copy number changes, gene expression, pathway activation, tumor heterogeneity, immune microenvironment, resistance mechanisms, and actionable surface targets. Results are delivered with ongoing scientific partnership and an AI-powered, queryable data platform.

## Market Standing
- **Valuation/Market Cap**: Not disclosed
- **Key Metric**: Total funding — conflicting reports: $10M (Seed, per DefineVC and Tracxn) or $13.5M (per company blog). [definevc.com](https://www.definevc.com/insights/putting-the-patient-at-the-center-of-cancer-science-with-valius-sciences) / [valiussciences.com](https://www.valiussciences.com/) (blog post)
- **Notable Investors/Partners**: 8VC, Basis Set Ventures (seed round)
- **Growth Signals**: Raised funding in early 2026; has worked with patients across 25+ cancer types; early cases identified new drug targets not found by prior diagnostics; hiring across key roles (Computational Biologist, Translational Scientist, Software Engineer, Operations Lead).

## Competitive Advantages
- **Maximalist, multi-omics approach**: Covers DNA, RNA, and protein comprehensively rather than limited panel testing; leaves no stone unturned.
- **Ongoing scientific partnership**: Unlike standard PDF-report diagnostics, Valius provides dedicated scientists who meet regularly with patients and physicians, and data remains accessible and queryable forever via AI.
- **Patient-centric model**: Direct-pay service (pricing $50k–$150k with discounts); focuses on biologically plausible targets regardless of cancer type; supports clinical trial matching, single-patient INDs, and recurrence monitoring.
- **Top-tier team**: Founders combine operational discipline, commercial rigor, and deep scientific credibility.

## Strategic Focus
- Scale the platform to reach more patients with rare, aggressive, or recurrent cancers.
- Continue refining the AI-powered data platform for real-time querying and analysis.
- Expand partnerships with oncologists and treatment centers to integrate Valius findings into care pathways.

## Why Work Here
- **Mission-driven**: Direct, immediate impact on cancer patients’ treatment options.
- **Interdisciplinary culture**: Hires computational biologists, scientists, engineers, and clinicians who span disciplines and don’t fit neatly into boxes.
- **Cutting-edge tech**: Work with whole genome, single-cell, spatial, and proteomic data at scale.
- **Autonomy & ownership**: Small, focused team with front-line patient interaction.
- **Location**: San Francisco (likely office-first; remote/hybrid policy not explicitly stated). “Outlier” culture emphasized.
- **Open roles**: Computational Biologist, Translational Scientist, Software Engineer, Operations Lead (as of 2026).

## Sources
1. [Valius Sciences Website](https://www.valiussciences.com/)
2. [Valius Sciences Careers Page](https://www.valiussciences.com/careers)
3. [DefineVC Investment Blog](https://www.definevc.com/insights/putting-the-patient-at-the-center-of-cancer-science-with-valius-sciences)
4. [Tracxn Company Profile](https://tracxn.com/d/companies/valius/__spxuU3YvDbNRZwJnIIruRczc89b40XA-xktgbWeCXkI)
5. [Ashby Careers Portal](https://jobs.ashbyhq.com/valiussciences)

## Other roles at Valius Sciences

- [Director of Translational Science](https://feeny.ai/job/director-of-translational-science-valius-sciences-san-francisco-svfhd275hh5n) — San Francisco, CA
- [Clinical Translational Scientist](https://feeny.ai/job/clinical-translational-scientist-valius-sciences-san-francisco-rch03b5c4vrz) — San Francisco, CA
- [Computational Biologist](https://feeny.ai/job/computational-biologist-valius-sciences-san-francisco-9hh0dj4aa8eq) — San Francisco, CA
- [Head/VP of Engineering](https://feeny.ai/job/head-vp-of-engineering-valius-sciences-san-francisco-0nf568e2qf06) — San Francisco, CA