---
title: 'Lab Manager, Aquaculture at Biohub'
canonical: 'https://feeny.ai/job/lab-manager-aquaculture-biohub-san-francisco-jbb8r64afpz6'
type: 'job'
last_seen: '2026-09-13'
---

# Lab Manager, Aquaculture at Biohub

- **Company:** Biohub
- **Location:** San Francisco, CA
- **Work type:** hybrid
- **Posted:** 2026-09-04
- **Last confirmed live:** 2026-09-13
- **Apply:** https://job-boards.greenhouse.io/biohub/jobs/8167915

## Job description

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.

The Team

Through our multi-dimensional imaging program, we build imaging tools that capture life across scales — from single proteins to whole organisms — revealing how proteins and cells function, communicate, and assemble into living systems. These observations are laying the groundwork for a new generation of AI models that can predict cellular behavior and guide the development of better treatments for widespread diseases. You can learn more about our work [here](https://biohub.org/imaging/).

Our work brings together three powerhouse universities - Stanford, UC Berkeley, and UC San Francisco - into a single collaborative technology and discovery engine.

Our Vision

- Pursue large scientific challenges that cannot be pursued in conventional environments
- Enable individual investigators to pursue their riskiest and most innovative ideas
- Facilitate research by scientists and clinicians at our home institutions and beyond

We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease.

The Opportunity

Biohub is seeking an Aquaculture Lab Manager to lead the day-to-day operation of its aquatic model-organism husbandry facility, ensuring the safe, efficient, and compliant husbandry of zebrafish and other aquatic species that underpin the Imaging Grand Challenge's research programs.

This role oversees the aquaculture system end to end — water quality, recirculating system performance, fish health and colony management, equipment readiness, and regulatory/EH&S compliance — and works closely with researchers, scientists, and platform teams to ensure the facility reliably supports ongoing and upcoming experiments.

This position is well-suited for a candidate with hands-on aquaculture or aquatic-model-organism facility management experience who can plan and execute semi-complex laboratory activities independently, translate operational objectives into concrete plans, and mentor junior lab staff.

## What You'll Do

- Plans, coordinates, and manages the aquaculture facility's day-to-day activities; manages schedules and resources to ensure efficient, uninterrupted operation of the aquatic facility.
- Works with researchers and scientists to understand laboratory and husbandry resource needs for the aquaculture environment; collects and organizes requests for additional equipment, feed, and supplies, and obtains requested items.
- Ensures readiness and availability of all aquaculture resources — including recirculating water systems, tanks, filtration and monitoring equipment, feed, and reagent chemicals; manages inventory of supplies and recommends efficiencies.
- Manages equipment moves and maintenance (e.g., tank cleaning, filter changes, system defrosting/descaling, sensor calibration) to keep the facility running at expected capacity.
- Works with EH&S consultants and/or Platform Managers, or independently, to develop and implement EH&S solutions for aquaculture-specific safety challenges (e.g., water chemistry, biosafety, waste handling); monitors equipment and activities to ensure adherence to safety protocols in compliance with federal, state, and organizational standards.
- Manages laboratory service contracts for assigned aquaculture equipment (e.g., recirculating aquaculture systems, water treatment units); works with researchers, scientists, or super users to understand maintenance or repair needs, and with service providers to ensure work aligns with expectations and contract terms.
- Works closely with facilities personnel to implement complex lab-plant upgrades and maintenance related to water, ventilation, electrical, gas, heating, and air conditioning systems supporting the aquaculture facility.
- Manages and coordinates preventative maintenance; conducts inspections of semi-complex to complex equipment (e.g., life-support systems, water quality monitors) and ensures repairs are made promptly to reduce unexpected downtime and protect animal welfare.
- Monitors laboratory equipment and usage to comply with EH&S requirements, protocols, policies, procedures, and established standards; identifies issues and works with EH&S consultants to implement solutions.
- Improves methods, systems, or tools that contribute to the broader research workstream; regularly develops solutions to recurring husbandry, water-quality, or facility-operations challenges.
- Translates workstream objectives from research programs into actionable husbandry and facility-operations plans.
- May act as a team lead for lab technicians or junior staff; trains and mentors staff on aquaculture procedures, animal husbandry, and safety practices.
- Documents SOPs, husbandry protocols, and facility records to support reproducibility, regulatory compliance, and continuity of operations.

## What You'll Bring

Required

- Demonstrated experience across all areas of aquaculture/lab operations, with in-depth specialization in at least one area (e.g., water quality management, recirculating system operation, or fish husbandry).
- Ability to communicate clearly, directly, and respectfully with multiple audiences, including researchers, scientists, vendors, and EH&S consultants.
- Proven knowledge of aquaculture facility practices and processes, including husbandry standards for aquatic model organisms (e.g., zebrafish).
- Strong understanding of semi-complex to complex scientific/aquaculture instruments and systems (e.g., recirculating aquaculture systems, water quality monitors, filtration units).
- Proven knowledge of lab equipment and procedures needed to support aquatic model-organism research; familiarity with animal welfare and biosafety requirements for aquatic species.
- Advanced experience and competency in single-focus lab operations, with the ability to translate theoretical knowledge into practical approaches involving research, analysis, and execution of action plans, as could be acquired through higher education and/or equivalent professional experience.
- Typically has 5-8 years of progressively complex, related professional experience in aquaculture, animal facility management, or laboratory operations.

## Preferred

- Direct experience with zebrafish or other aquatic model-organism husbandry in a research setting.
- Hands-on experience operating and troubleshooting recirculating aquaculture systems (RAS).
- Experience developing or maintaining water quality management and biosecurity protocols.
- Experience mentoring or training junior lab staff or technicians.
- Experience contributing to the design or build-out of new aquaculture facilities or lab space.
- Familiarity with IACUC or equivalent regulatory/compliance frameworks governing aquatic model organisms.

## Compensation

The San Francisco, CA base pay range for a new hire in this role is $106,000.00 - $133,000. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.

This position may be eligible to participate in our discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with our total rewards philosophy and may vary by role.

## Benefits for the Whole You

We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.

- Provides a generous employer match on employee 401(k) contributions to support planning for the future.
- Paid time off to volunteer at an organization of your choice.
- Funding for select family-forming benefits.
- Relocation support for employees who need assistance moving

If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.

#LI-Hybrid

## About Biohub

## Company Overview
- **One-liner**: Biohub (Chan Zuckerberg Biohub) is a nonprofit research organization building AI-powered tools and engineered cells to detect, treat, and ultimately cure age-related diseases.
- **Entity Type**: Nonprofit (Private) – parent institution is the Chan Zuckerberg Initiative; funded by a $600 million endowment from Mark Zuckerberg and Priscilla Chan.
- **Headquarters**: Redwood City, California, United States (with additional offices in San Francisco, Chicago, New York)
- **Founded**: 2016
- **Founders**: Priscilla Chan and Mark Zuckerberg (co-founded as part of the Chan Zuckerberg Initiative; initial scientific leadership by Stephen Quake and Joseph DeRisi)

## Core Business
- **Primary industry/industries**: AI-powered biology, biotechnology research, healthcare
- **Target customers**: Scientists and researchers in academia and industry; indirectly benefits biotech and pharmaceutical companies through open-source models and foundational research; also invests in early‑stage companies via Science Ventures.
- **Mission or purpose statement**: “To cure or prevent all disease” by combining frontier artificial intelligence with frontier biology to understand why disease happens and how to correct it.

## Products & Services
- **AI Models for Biology**: Frontier AI models trained on large‑scale biological datasets (e.g., a world model of protein biology) that allow scientists to generate, test, and refine new protein designs. These are released as open discovery engines.
- **Multi‑Dimensional Imaging Platforms**: Advanced tools (e.g., laser phase plate microscopy) that capture life from single proteins to whole organisms, revealing how cells function and communicate. Enables new AI models to predict cellular behavior.
- **High‑Throughput Data Generation Engines**: Proprietary platforms for measuring, imaging, and programming biology at unprecedented scale, powering AI model training and hypothesis generation.
- **Science Ventures**: An investment arm that supports early‑stage companies aligned with Biohub’s Grand Challenges (e.g., Somite AI, Adaptyx Biosciences).
- **Grants & Collaborations**: Targeted grantmaking and open competitions to expand scientific research, including the Investigator Program for external scientists.

## Market Standing
- **Valuation/Market Cap**: Not applicable (nonprofit); endowment of US$600 million (initial funding in 2016).
- **Key Metric**: ~367 employees (as of mid‑2025); operating in 5 countries (US, UK, France, Canada, Netherlands); active job postings: 35+.
- **Notable Investors/Partners**: Chan Zuckerberg Initiative (primary funder); academic partners include UC Berkeley, UCSF, Stanford; recent investments in Somite AI and Adaptyx Biosciences.
- **Growth Signals**: Headcount growing 1.5% monthly; quarterly job posting increase of 133%; expanding into new locations (Chicago, New York); launching open‑source biological AI models.

## Competitive Advantages
- **Scale of Compute & Data**: Unprecedented access to frontier AI compute clusters combined with unique, large‑scale biological datasets (genomics, proteomics, imaging).
- **Open Science Model**: Results and models are shared openly, creating a virtuous feedback loop with the global research community.
- **Talent Density**: Strong hiring pipeline from top institutions (Stanford, UC Berkeley, UCSF, Caltech) and a collaborative culture across AI, engineering, and biology.
- **Founder Backing**: Deep, sustained funding from Mark Zuckerberg and Priscilla Chan ensures long‑term, risk‑taking research without commercial pressure.

## Strategic Focus
- **Grand Challenges**: Decoding inflammation, early detection of age‑related diseases (cancer, Alzheimer’s, Parkinson’s), rare disease research, and building a “world model” of protein biology.
- **AI‑First Biology**: Developing AI models that can predict cellular behavior and guide targeted treatment “only when and where needed.”
- **Platform Scaling**: Expanding high‑throughput data generation engines and imaging tools to break through sparsity of biological data.
- **Open Collaboration**: Accelerating translation from basic discovery to patient benefit through partnerships, grants, and open‑source releases.

## Why Work Here
- **Mission‑Driven**: Opportunity to work at the intersection of AI and biology on problems that aim to eliminate the most significant causes of death worldwide.
- **Culture & Team**: A collaborative team of scientists, engineers, and ML experts from top universities and companies (Genentech, EvolutionaryScale, etc.). Emphasis on “audacious, important scientific challenges.”
- **Work Policy**: Hybrid model for many roles in Redwood City and New York; some positions are onsite in Chicago or San Francisco.
- **Compensation & Perks**: Competitive salaries (e.g., Computational Biologist II ~$99k/yr, Clinical Lab Specialist ~$58k/yr); strong benefits typical of a well‑funded nonprofit; no equity, but meaningful mission impact.
- **Growth**: Rapid hiring expansion across AI research, engineering, and biology; opportunity to work on frontier AI compute infrastructure and foundational biology models.

## Sources
1. [biohub.org](https://biohub.org/)
2. [Careers page – Greenhouse](https://job-boards.greenhouse.io/biohub)
3. [LinkedIn – CZ Biohub](https://www.linkedin.com/company/cz-biohub)
4. [Wikipedia – Chan Zuckerberg Biohub](https://en.wikipedia.org/wiki/Chan_Zuckerberg_Biohub) (referenced via search result)

## Other roles at Biohub

- [Postdoctoral Fellow/Scientist I, Synthetic Spatial Omics (Imaging Technology)](https://feeny.ai/job/postdoctoral-fellow-scientist-i-synthetic-spatial-omics-imaging-technology-1nyrb04bmy85) — New York, NY
- [Scientist II, Scaling Lead](https://feeny.ai/job/scientist-ii-scaling-lead-biohub-san-francisco-9xk1n38bp90g) — San Francisco, CA
- [Computational Biologist, Immune Cell Repolarization](https://feeny.ai/job/computational-biologist-immune-cell-repolarization-biohub-new-york-dt3na0g615eh) — New York, NY
- [Research Associate II, Structural & Cellular Biology (Proteomics & CryoET)](https://feeny.ai/job/research-associate-ii-structural-cellular-biology-proteomics-cryoet-biohub-ge4pjxz6hq0k) — Redwood City, CA
- [Staff Research Scientist, AI Safety](https://feeny.ai/job/staff-research-scientist-ai-safety-biohub-new-york-68fy1gymrhmg) — New York, NY
- [Computational Biologist, Synthetic Spatial Omics](https://feeny.ai/job/computational-biologist-synthetic-spatial-omics-biohub-new-york-srwtkdew50sf) — New York, NY
- [Principal Technical Program Manager, Science, Imaging](https://feeny.ai/job/principal-technical-program-manager-science-imaging-biohub-redwood-city-v9dbd6a743s4) — Redwood City, CA
- [Director, Virtual Biology Initiative](https://feeny.ai/job/director-virtual-biology-initiative-biohub-redwood-city-pwf0p3w6k56w) — Redwood City, CA
- [Staff Data Scientist, Imaging](https://feeny.ai/job/staff-data-scientist-imaging-biohub-redwood-city-20s3vpyx8gb5) — Redwood City, CA
- [Lab Manager](https://feeny.ai/job/lab-manager-biohub-redwood-city-zkr8595zv6aq) — Redwood City, CA