---
title: 'Lab Operations Specialist at RefinedScience'
canonical: 'https://feeny.ai/job/lab-operations-specialist-refinedscience-aurora-6vecey0852bq'
type: 'job'
last_seen: '2026-09-05'
---

# Lab Operations Specialist at RefinedScience

- **Company:** RefinedScience
- **Location:** Aurora, CO
- **Posted:** 2026-09-02
- **Last confirmed live:** 2026-09-05
- **Apply:** https://job-boards.greenhouse.io/refinedscience/jobs/5414502008

## Job description

Laboratory Operations Specialist

At RefinedScience, our mission is to advance care by bringing together the best science, data and minds – disease by disease, patient by patient, cell by cell to discover pathways to life beyond disease.

## WHAT WE ARE LOOKING FOR

We are seeking a detail-oriented and proactive Laboratory Operations Specialist to support both the day-to-day operational infrastructure of our lab and our scientific research pipeline. This role is roughly split between lab operations/compliance (~60%) and hands-on scientific project contribution (~40%), making it ideal for someone who enjoys variety and wants exposure to cutting-edge -omics research in a startup environment. The ideal candidate is a BS or MS graduate in a life sciences field with 2 to 5 years of relevant laboratory experience.

## KEY ACTIVITIES

- Manage procurement, maintenance, decontamination, calibration, and repair of all laboratory equipment
- Oversee inventory and supply chain logistics for lab consumables and reagents
- Maintain physical sample storage and manage the biorepository database
- Ensure all laboratory activities comply with institutional, local, state, and federal safety regulations, including OSHA and biosafety guidelines
- Oversee lab safety protocols, hazardous waste disposal procedures, and general laboratory hygiene standards
- Serve as a point of contact for safety audits and inspections
- Conduct hands-on in vitro research supporting ongoing pipeline programs, with a strong focus on -omics studies (e.g., genomics, proteomics, transcriptomics)
- Support scientists in executing complex, multi-day experiments, including setup and operation of liquid/fluid handlers and other lab automation equipment
- Document and archive experimental protocols, data, analyses, and conclusions in accordance with established SOPs and data integrity standards

## MUST HAVES

- BS or MS in Biology, Biochemistry, Molecular Biology, Biotechnology, or a related life sciences field
- 2–5 years of relevant laboratory experience (academic, industry, or internship experience considered)
- Hands-on experience with standard molecular/cell biology techniques (e.g., PCR, pipetting, cell culture)
- Familiarity with lab safety and biosafety practices (e.g., BSL-1/BSL-2)
- Strong organizational skills and attention to detail
- Ability to manage multiple priorities in a fast-paced startup environment

## NICE TO HAVES

- Experience with -omics workflows (genomics, proteomics, transcriptomics, metabolomics)
- Experience operating liquid handlers or lab automation systems
- Experience with laboratory inventory management systems (LIMS) or biorepository databases
- Experience carrying out tasks in a GLP setting
- Prior experience in a startup or small-team lab setting

## WHY YOU’LL LOVE REFINED SCIENCE

## Team + Values

At RefinedScience, we seamlessly integrate top-tier clinical and biological data with expert knowledge to provide unparalleled insights. We maximize patient impact with these unique insights by optimizing clinical trial probability of success and time to actionable results. We work across biopharma and we are a trusted partner in achieving better results, faster – working together to unlock strategic advantage.

## Our Values

- Act with Purpose – We believe in rigor through deliberate and thoughtful actions
- Be Curious – Curiosity is the spark that ignites innovation and growth
- Take Ownership – True ownership leads to pride and commitment in the work we do
- Invest in Relationships – Building strong connections is the foundation for effective collaboration and trust for long term success
- Embrace Agility – We celebrate agile thinking, resilience, and adaptability

## WHAT WE OFFER

- The target salary range is $65,000 to $76,000 annually.
- Base pay offered may vary within the posted range based on several factors, including but not limited to education, job-related knowledge, skills, experience, and location.

## BENEFITS

- Medical, Dental and Vision insurance
- Life, AD&D, Short-term and Long-term Disability Insurance (none is 100% covered)
- HSA Spending Accounts
- 22 Vacation days
- 10 Paid Holidays and Sick Time (120 hours per year)
- 401(K) Plan

## About RefinedScience

## Company Overview
- **One-liner**: RefinedScience combines longitudinal patient data, biobank samples, and AI-powered analysis to accelerate precision oncology drug development for pharma partners.
- **Entity Type**: Private (joint venture between CU Anschutz and UCHealth)
- **Headquarters**: Aurora, Colorado, United States
- **Founded**: 2019
- **Founders**: Joint venture of CU Anschutz and UCHealth; key leadership includes Clay Smith (Chief Innovation Officer), Grant Weller (CTO), Dan Pollyea (Chief Medical Officer), and others.

## Core Business
- **Primary industry**: Biotechnology Research / Precision Oncology Drug Discovery
- **Target customers**: Pharmaceutical and biotech companies (B2B) seeking target validation, patient stratification, and clinical trial support in oncology
- **Mission or purpose**: "To advance care by bringing together the best science, data and minds – disease by disease, patient by patient, cell by cell to discover pathways to life beyond disease."

## Products & Services
- **RefinedScience Platform**: Unified access to UCHealth longitudinal patient data, biobank samples, and EHR data linked to biological samples across 7 oncology indications (AML, MDS, PDAC, Ovarian, Esophageal, Glioblastoma, DLBCL). Includes AI-powered software tools: scExploreR (single-cell data explorer), Marksman (target identification), Scout (AI co-scientist), and PULSE.
- **Biological Validation Services**: 700+ assays developed, functional drug testing on primary liquid tumors, patient-derived organoids and spatial transcriptomics for solid tumors.
- **ADC Target Discovery Platform**: Systematic ADC target evaluation in AML using single-cell surface antigen mapping at tumor-initiating cell (TIC) level, functional primary tissue models, and longitudinal clinical data.
- **Data Partnerships**: Longitudinal AML dataset (300+ venetoclax/azacitidine treated patients with CITE-seq) available on Verily Exchange. Multi-year collaboration with Verily to create AI-ready biomedical data pipelines.

## Market Standing
- **Valuation/Market Cap**: Not publicly available (private joint venture)
- **Key Metric**: Total funding not disclosed; revenue not publicly available; 28 employees (+32% YoY growth); 1,033 LinkedIn followers (+93.8% yearly growth)
- **Notable Investors/Partners**: Verily (strategic collaboration), ImCheck Therapeutics (supported FDA Breakthrough Therapy Designation, later acquired by Ipsen), UCHealth, CU Anschutz
- **Growth Signals**: 32% headcount growth year-over-year; active hiring for multiple roles (Cloud Infrastructure Engineer, Bioinformatics ML Intern); expansion of AI co-scientist tools; ADC target discovery program in AML with active pharma conversations

## Competitive Advantages
- **Unique institutional access**: As a joint venture of CU Anschutz and UCHealth, RefinedScience has exclusive access to deep clinical data and patient tissue that external vendors cannot replicate.
- **Integrated capabilities**: Combines clinically-linked single-cell datasets, biological validation in real patient tissue, and AI analysis tools – a "biology-first" approach that AI-only companies lack.
- **Proven pharma impact**: Work with ImCheck Therapeutics contributed to FDA Breakthrough Therapy Designation and subsequent acquisition by Ipsen.
- **Single-cell resolution**: Focus on tumor-initiating cell biology, critical for ADC target discovery in AML.

## Strategic Focus
- **Current priorities**: Expanding ADC target discovery in AML; deepening AI/ML capabilities (generative AI, LLMs for biological data interpretation); scaling data partnerships (Verily Exchange); growing team across bioinformatics, data engineering, and scientific project management.
- **Direction**: Move drugs forward by providing pharma partners with biological evidence for target validation, patient selection, and clinical execution – disease by disease.

## Why Work Here
- **Culture**: "Biology-first" company integrating top-tier clinical data, AI, and lab science. Values include collaboration, innovation, and patient impact.
- **Work policy**: Hybrid or remote options available (some roles listed as remote; Aurora, CO office with "OnSite Workspace" – employees work from physical offices, but roles like Bioinformatics ML Intern are hybrid/remote).
- **Notable perks**: Opportunity to work at the intersection of clinical data, single-cell biology, and AI; direct impact on drug development and patient outcomes; multidisciplinary team spanning biostatistics, data science, hematology, oncology, and precision medicine.
- **Engineering culture**: Strong emphasis on reproducible research, modern ML frameworks (PyTorch, TensorFlow, JAX), and cutting-edge single-cell analysis tools. Intern roles offer $34-$38/hour for Ph.D. candidates.

## Sources
1. [refinedscience.com](https://www.refinedscience.com/)
2. [LinkedIn - RefinedScience](https://www.linkedin.com/company/refinedscience)
3. [Greenhouse - Bioinformatics Machine Learning Intern](https://job-boards.greenhouse.io/refinedscience/jobs/5154947008)
4. [Built In - RefinedScience](https://builtin.com/company/refinedscience)
5. [Built In Colorado - RefinedScience](https://www.builtincolorado.com/company/refinedscience)

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