---
title: 'Laboratory Operations Associate at Serif Biomedicines, Inc.'
canonical: 'https://feeny.ai/job/laboratory-operations-associate-serif-biomedicines-inc-cambridge-stbt1pbzxjn6'
type: 'job'
last_seen: '2026-11-04'
---

# Laboratory Operations Associate at Serif Biomedicines, Inc.

- **Company:** Serif Biomedicines, Inc.
- **Location:** Cambridge, MA
- **Posted:** 2026-10-01
- **Last confirmed live:** 2026-11-04
- **Apply:** https://job-boards.greenhouse.io/serif/jobs/8860010002

## Job description

Company Summary:

Serif Biomedicines is a privately held, early-stage biotechnology company developing a novel approach to gene therapy that can address currently untreatable diseases.

Serif was founded by Flagship Pioneering, an innovation enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Syros Pharmaceuticals (SYRS), Seres Therapeutics (NASDAQ:MCRB), Generate Biomedicines, Tessera Tx, Evelo Biosciences (EVLO), and Indigo Agriculture.

Position Summary:

We are seeking a highly organized and hands-on Laboratory Operations Associate to support sample management, inventory, and day-to-day operations for our CMC and broader laboratory teams. This candidate will work closely with the CMC team to build and maintain an efficient sample management and inventory system, help organize final cargo and coordinate handoffs across teams, and support procurement of key reagents and consumables. We are looking for an individual with strong bench and instrument experience, exceptional organizational skills, and the ability to work cross-functionally with scientists and operations leadership. This is an excellent opportunity for a candidate with sample management and/or lab operations experience who is looking to grow into a lab management role, as part of a dynamic, fast-paced, and collaborative team.

Key Responsibilities:

CMC Support

- Work closely with the CMC team to build out and maintain their sample management and inventory system
- Organize final cargo and support handoffs of materials to other teams across the company
- Provide regular updates on cargo inventory status to the Director of CMC, Head of Analytics, Senior Manager of Operations, and other team leads
- Partner with scientists and the Senior Manager of Operations to organize inventory and coordinate procurement of key enzymes, buffers, and other consumables.

Lab Operations Support

- Run decontamination and cleaning protocols on Fragment Analyzers and flow cytometers (including the yeast cytometer and sorter) on a weekly basis
- Complete daily “Lab Tasks” to maintain lab organization cleanliness, and readiness.
- Support lab space optimization efforts as the team grows within an increasingly confined footprint
- Troubleshoot key laboratory equipment and support routine equipment upkeep
- Perform Category B equipment maintenance (freezer defrosts, incubator PMs, centrifuge calibrations, pipette calibration scheduling, etc.)
- Provide procurement support for general lab consumables

Lab Onboarding Support

- Assist in executing new lab member onboarding, including bench allocation; procurement of benchtop equipment and consumables (pipettes, centrifuges, freezers);
- Support fridge and freezer allocation; safety training checks; and small lab consumables procurement.
- Help ensure team members are set up efficiently to work safely and effectively in the lab.

Education and Qualifications:

- BS degree in Biology, chemistry, Biochemistry or related field
- 2+ years of experience in laboratory operations, sample management or both
- Hands-on bench experience at the Research Associate or Associate Scientist level
- Experience in sample management and/or laboratory operations (experience in both is a plus)
- Hands-on experience with cytometers, Fragment Analyzers, and chromatography instruments
- Strong communication skills and the ability to work cross-functionally with scientists and operations leadership
- Ability to lift up to 30 lbs
- Candidates with sample management experience who are looking to grow into a lab management role are strongly encouraged to apply
- Experience working with Benchling, specifically Workflows and Inventory is desirable.
- Experience with other LIMS or inventory systems is a plus.

More About Flagship Pioneering

We are creative optimists and we would love for you to consider joining our team!  See all our open opportunities across Flagship Pioneering’s Ecosystem!

Flagship Pioneering conceives, creates, resources, and develops first-in-category life sciences companies to transform human health and sustainability. Since its launch in 2000, the firm has applied a unique hypothesis-driven innovation process to originate and foster more than 100 scientific ventures, resulting in over $34 billion in aggregate value. To date, Flagship is backed by more than $4.4 billion of aggregate capital commitments, of which over $1.9 billion has been deployed toward the founding and growth of its pioneering companies alongside more than $10 billion of follow-on investments from other institutions. The current Flagship ecosystem comprises 41 transformative companies, including:  Axcella Health (NASDAQ: AXLA), Denali Therapeutics (NASDAQ: DNLI), Evelo Biosciences (NASDAQ: EVLO),  Foghorn Therapeutics, Indigo Ag, Kaleido Biosciences (NASDAQ: KLDO), Moderna (NASDAQ: MRNA), Rubius Therapeutics (NASDAQ: RUBY), Sana Biotechnology, Seres Therapeutics (NASDAQ: MCRB), and Syros Pharmaceuticals (NASDAQ: SYRS).

We believe pioneering is best done by teams, and that it is a process that can be taught, learned, and replicated.  Learn more about our [Company Creation Model](https://www.flagshippioneering.com/process).

[Can Breakthrough Innovations Be Made Systematically? A Conversation With Noubar Afeyan](https://www.flagshippioneering.com/stories/can-innovations-be-made-systematically-a-conversation-with-noubar-afeyan), Flagship Pioneering’s CEO.

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies:  Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates.  The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team.   Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

Privacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.

The salary range for this role is $72,000 - $99,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Serif Biomedicines currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Serif Biomedicines's good faith estimate as of the date of publication and may be modified in the future. Privacy Notice for Applicants: When you apply for a role at Serif Biomedicines, Inc., a Flagship Pioneering portfolio company, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact privacy@flagshippioneering.com.

## About Serif Biomedicines, Inc.

## Company Overview
- **One-liner**: Serif Biomedicines is pioneering Modified DNA as a new class of genetic medicine, using nucleic acid chemistry, synthetic biology, delivery science, and AI to create programmable, durable, and redosable DNA therapeutics.
- **Entity Type**: Private (Founded by Flagship Pioneering)
- **Headquarters**: Cambridge, MA, USA
- **Founded**: 2026 (public launch in April 2026)
- **Founders**: Originated at Flagship Pioneering; Founding team includes Jacob (Jake) Rubens, PhD (CEO), Matt Kennedy, PhD (CSO), and others.

## Core Business
- **Primary industry**: Biotechnology / Genetic Medicines
- **Target customers**: B2B (pharma/biotech partnerships) and B2G (therapeutic development for rare diseases and immune programming)
- **Mission**: To build a future where DNA becomes the source code for medicines that can be tailored across diseases and scaled for global impact.

## Products & Services
- **Modified DNA Platform**: A proprietary technology that chemically modifies DNA to minimize innate immunogenicity during delivery into cells. Once inside the nucleus, the Modified DNA reverts to unmodified DNA, enabling transcription into therapeutic RNA and proteins. This platform combines the best features of mRNA and gene therapy while mitigating their limitations (durability, redosability, cell-specific expression).
- **mRNA Co-factors**: Delivered alongside Modified DNA, these transiently express proteins that enhance nuclear entry and gene expression.
- **AI-Enabled Design-Build-Test-Learn Cycle**: Integrates AI to optimize DNA and mRNA co-factor sequences and lipid nanoparticle (LNP) formulations by learning from massive datasets.
- **Therapeutic Pipeline**: Initial drug discovery programs focused on rare diseases and immune programming.

## Market Standing
- **Valuation/Market Cap**: Not disclosed (private, Flagship Pioneering portfolio company)
- **Key Metric**: Total Funding — Not publicly disclosed (launched with Flagship Pioneering backing; no specific funding round announced)
- **Notable Investors/Partners**: Flagship Pioneering (originator and primary backer); Board includes Noubar Afeyan (Flagship CEO), John Maraganore (founding CEO of Alnylam), Andrew Allen (CEO of Tessera Therapeutics), and others.
- **Growth Signals**: Public launch in April 2026 with significant press coverage; presenting data at ASGCT 2026; actively hiring across multiple R&D functions (Protein Engineering, LNP Process & Development, Immunology, Bioanalytics, Molecular Biology).

## Competitive Advantages
- **Novel Platform Technology**: Serif is the first company to establish Modified DNA as a therapeutic modality, creating a new category of genetic medicine that combines the durability of gene therapy with the redosability and programmability of mRNA.
- **Flagship Pioneering Backing**: Originated and funded by Flagship, a top-tier biotech venture creation firm with a track record of building category-defining companies (Moderna, Tessera, etc.).
- **Integrated Capability Stack**: Combines nucleic acid chemistry, synthetic biology, delivery science (LNPs), and AI/ML for optimization — a full-stack approach to genetic medicine.
- **Strong IP & Scientific Team**: Leadership includes veterans from Flagship, Alnylam, and Tessera, with deep expertise in nucleic acid discovery, development, and delivery.

## Strategic Focus
- **Initial Therapeutic Areas**: Rare diseases and immune programming, where Modified DNA’s durability, redosability, and cell-specific expression offer clear advantages.
- **Platform Expansion**: Building scalable manufacturing processes and AI-driven design cycles to enable broad therapeutic application across diseases.
- **Talent Acquisition**: Actively hiring across R&D functions to build out the platform and pipeline.

## Why Work Here
- **Pioneering Science**: Opportunity to work on a first-in-class technology that could redefine genetic medicine — comparable to the early days of mRNA therapeutics.
- **Flagship Ecosystem**: Access to the resources, network, and expertise of Flagship Pioneering, one of the most successful biotech incubators.
- **Culture**: Described as a team of scientists, engineers, and company builders united by a mission to create a new foundational biotechnology. Emphasis on collaboration and innovation.
- **Location**: Cambridge, MA — a global hub for biotech and life sciences.
- **Growth Stage**: Early-stage (just launched in April 2026), offering significant impact and career growth potential for early hires.
- **Work Policy**: Not explicitly stated, but typical for early-stage biotech in Cambridge — likely on-site or hybrid.

## Sources
1. [serifbiomedicines.com](https://serifbiomedicines.com)
2. [serifbiomedicines.com/team](https://serifbiomedicines.com/team)
3. [serifbiomedicines.com/science](https://serifbiomedicines.com/science)
4. [flagshippioneering.com](https://www.flagshippioneering.com/companies/serif-biomedicines)
5. [job-boards.greenhouse.io/serif](https://job-boards.greenhouse.io/serif/jobs/8511741002)

## Other roles at Serif Biomedicines, Inc.

- [Senior Scientist, LNP Formulations](https://feeny.ai/job/senior-scientist-lnp-formulations-serif-biomedicines-inc-cambridge-e6as2tmxztgp) — Cambridge, MA
- [Scientist, In Vivo Pharmacology](https://feeny.ai/job/scientist-in-vivo-pharmacology-serif-biomedicines-inc-cambridge-ss8e62xdrcqp) — Cambridge, MA
- [Associate Scientist, Bioanalytical Assays](https://feeny.ai/job/associate-scientist-bioanalytical-assays-serif-biomedicines-inc-cambridge-7e493d7k67nb) — Cambridge, MA
- [Senior Scientist, Analytical Development and Quality Control](https://feeny.ai/job/senior-scientist-analytical-development-and-quality-control-serif-biomedicines-1ewhtadm3tmg) — Cambridge, MA
- [Laboratory Operations Associate](https://feeny.ai/job/laboratory-operations-associate-flagship-pioneering-inc-cambridge-4rcw5hxsyxez) — Cambridge, MA