---
title: 'Manager, Facilities Engineering at Vaxcyte'
canonical: 'https://feeny.ai/job/manager-facilities-engineering-vaxcyte-san-carlos-9z48ebpsa6x8'
type: 'job'
last_seen: '2026-10-19'
---

# Manager, Facilities Engineering at Vaxcyte

- **Company:** Vaxcyte
- **Location:** San Carlos, CA
- **Posted:** 2026-10-08
- **Last confirmed live:** 2026-10-19
- **Apply:** https://boards.greenhouse.io/vaxcyte/jobs/5440072008?gh_jid=5440072008

## Job description

Join our Mission to Protect Humankind!

Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.

WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values:

*RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered.

*AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.

*LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives.

*MODEL EXCELLENCE:  The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.

Summary:

Vaxcyte is looking for a Manager, Facilities Engineering to be responsible for managing the maintenance and improvement of our office and laboratories. The Manager, Facilities Engineering will be responsible for managing all facility engineers and facility technicians. You will be responsible for assessing the facility’s resource requirements, designing, and optimizing the facility’s layout and critical operational systems, and overseeing the maintenance of infrastructure and equipment.

The successful Manager, Facilities Engineering should be able to manage the development and implementation of utility plans, perform system evaluations, and establish operational efficiency. A top-notch Manager, Facilities Engineering should have excellent project management skills and strong knowledge of structural code requirements. They should also be an energetic professional who thrives wearing multiple hats, has owned a wide range of operational office and lab responsibilities, and is able to think and work independently. A successful candidate is well organized, flexible, creative and enjoys the challenges of managing a diverse and energetic office space. This is a full-time, on-site role that reports to the Director, Facilities.

Essential Functions:

- Manage the facility engineer’s and facility technician’s day-to-day tasks and development.
- Managing all corrective maintenance for all facility assets.
- Oversee and maintain the PM schedule for all facility assets.
- Determining facility and lab equipment specifications and requirements.
- Analyzing project costs and helping prepare draft budgets.
- Support developing specifications and implementation of facility and lab equipment, equipment layout, other facility and lab systems, and controls.
- Evaluating operational systems and facility and lab infrastructure to ascertain and improve operational efficiencies.
- Planning and coordinating facility and lab infrastructure and equipment maintenance schedules and activities.
- Manage external and internal vendors.
- Manage the install of new laboratory equipment.
- Manage ongoing preventive maintenance and repair work on office mechanical, electrical, and other installed systems, and lab equipment.
- Maintain all Vaxcyte HVAC systems and associated equipment, electrical equipment, plumbing and gas systems, building management system (BMS), and office and lab repairs.
- Maintain and assure the proper function of the facility and its Mechanical, Electrical, Plumbing and DI Water Systems including repairing minor malfunctions of any of the components in and around the facility.
- Coordinating and overseeing maintenance contractors performing maintenance activities.
- Manage the BMS system, fire/life safety, and other systems required for facilities.
- Preparing reports and compliance documentation.
- Ensuring compliance with relevant regulations, building codes, and health and safety standards.
- Perform facility inspection and report on conditions affecting operations.
- Comply with all safety procedures and requirements.
- Process work requests and turn in completed work requests in a timely and professional manner.
- Respond to emergencies and support after-hours office/lab needs and activities as required.
- Assist lab operations team in troubleshooting equipment.
- Knowledge and working understanding of Computerized Maintenance Management System (CMMS) systems supporting building and lab equipment is a plus.

Requirements:

- Associate degree in mechanical, electrical, or industrial engineering.
- At least 5-7 years of experience as facilities engineer, biotechnology metrology or in a similar role. At least 2-3 years’ experience in leadership.
- Experience with AutoCAD, SAP, and CMMS systems.
- Knowledge of the building process and construction principles.
- Knowledge of relevant regulations and building codes.
- Good verbal and written communication skills.
- Troubleshooting and problem-solving skills.
- Project management skills.
- High level of integrity and ethics with the ability to maintain confidentiality.
- Strong organizational and interpersonal skills.
- Ability to manage multiple priorities efficiently.
- Desire to work in a fast-paced environment.
- Intermediate PC skills including MS Office suite. Must be able to efficiently use computers to write reports, emails, and provide written communication to leadership.
- Standing, Walking, Sitting, Reading, Stooping, climbing Ladders, crawling in / through low spaces.
- All Vaxcyte employees require vaccination against COVID-19.
- Heavy Lifting and Moving, Computers and Related Equipment, Heavy Equipment up to 70 lbs.
- Other combinations of education and/or experience may be considered.

Reports to: Director, Facilities

Location: San Carlos, CA

Work Arrangement (may be adjusted based on business needs, job responsibilities, or changes to company policy):

Onsite (5 days per week onsite)

Compensation:

The compensation package will be competitive and includes comprehensive benefits and an equity component.

Salary Range: $144,000 - $169,000 (SF Bay Area). Salary ranges for non-California locations may vary.

## Equal Opportunity

We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.

Recruitment Fraud Notice

Please be aware of fraud or scams from individuals, organizations and/or internet sites claiming to represent Vaxcyte in recruitment activities. Vaxcyte has an established recruitment process for all positions prior to issuing an offer for employment and we will never extend unsolicited employment offers or ask candidates to provide financial or sensitive personal information as part of the application process. All legitimate communication from Vaxcyte will come from an official @vaxcyte.com email address. Qualified and interested candidates should apply to current openings at [vaxcyte.com/careers](https://vaxcyte.com/careers/).

## About Vaxcyte

## Company Overview
- **One-liner**: Vaxcyte is a clinical-stage biotechnology company re-engineering how vaccines are made to eliminate bacterial infections, using a cell-free protein synthesis platform to develop high-fidelity, broad-spectrum vaccines.
- **Entity Type**: Public (Ticker: PCVX)
- **Headquarters**: San Carlos, California, United States
- **Founded**: 2013 (as SutroVax; rebranded to Vaxcyte in 2020)
- **Founders**: Not publicly available (the company emerged from Sutro Biopharma’s spin-out)

## Core Business
- **Primary industry**: Biotechnology / Vaccines (Infectious Disease)
- **Target customers**: Global healthcare systems, public health organizations, and ultimately patients (B2B/Institutional); the company develops vaccines for both pediatric and adult populations.
- **Mission or purpose**: To protect humankind from the consequences of bacterial infections, eliminating diseases like invasive pneumococcal disease, Group A Strep, and Shigella.

## Products & Services
- **VAX-31 (31-valent PCV)**: A broad-spectrum pneumococcal conjugate vaccine candidate in Phase 3 for adults and Phase 2 for infants. Designed to cover over 95% of circulating IPD serotypes in U.S. adults 50+ and ~94% in infants. FDA Breakthrough Therapy designation granted.
- **VAX-24 (24-valent PCV)**: A pneumococcal conjugate vaccine candidate in Phase 2 for infants, designed to cover more serotypes than any infant PCV on the market today.
- **VAX-A1 (Group A Strep)**: A preclinical conjugate vaccine candidate for Group A Strep, a disease with no currently approved vaccine. Phase 1 first-in-human study (adults) underway in Australia.
- **VAX-GI (Shigella)**: A novel preclinical vaccine candidate targeting Shigella, a leading cause of diarrheal disease.
- **Platform Technology**: A proprietary cell-free protein synthesis platform that enables site-specific, carrier-sparing conjugation to produce precisely targeted vaccines with enhanced immunogenicity.

## Market Standing
- **Valuation/Market Cap**: ~$16.7 billion (as of early July 2026)
- **Key Metric**: Total funding raised (private) is not applicable; as a public company, key metrics include cash position (~$2.0 billion as of Q1 2026) and R&D investment. The company is pre-revenue.
- **Notable Investors/Partners**: Major institutional investors include Baker Bros. Advisors, Fidelity, and funds managed by BlackRock. Key partnership: exclusive license agreement with Sutro Biopharma for its cell-free protein synthesis platform.
- **Growth Signals**: 
  - Up to $1 billion commitment to expanding U.S. manufacturing with a new facility in North Carolina.
  - VAX-31 Phase 3 program (OPUS-1, OPUS-2, OPUS-3) topline data expected Q4 2026 – H1 2027.
  - Headcount growth: actively hiring across 100+ roles (Analytical, Commercial, Clinical, Conjugation, Quality, Regulatory).
  - Recognized as a Great Place to Work and Best Workplace in BioPharma (multiple years).

## Competitive Advantages
- **Broadest-spectrum PCV candidates**: VAX-31 is the broadest-spectrum pneumococcal conjugate vaccine in the clinic, targeting up to 31 serotypes.
- **Differentiated platform**: Cell-free protein synthesis allows for the creation of complex, high-fidelity vaccines that can overcome bacterial defense mechanisms (e.g., capsule-switching) that limit conventional cell-based vaccines.
- **Carrier-sparing technology**: Site-specific conjugation enables a higher valency (more serotypes) without compromising immunogenicity or tolerability.
- **Manufacturing scale**: Significant investment in U.S.-based production capacity provides a long-term supply chain advantage and aligns with "Investing in America" initiatives.

## Strategic Focus
- **Primary**: Advance VAX-31 and VAX-24 through late-stage clinical trials to secure regulatory approval and establish a new standard of care for pneumococcal disease.
- **Pipeline expansion**: Advance VAX-A1 (Group A Strep) and VAX-GI (Shigella) candidates through early clinical development.
- **Manufacturing**: Scale up internal manufacturing capabilities to support commercial launch and global supply.
- **Commercial readiness**: Building a commercial organization (e.g., hiring a VP of U.S. Market Access & Pricing, Senior Director of Product Launch) to prepare for potential VAX-31 launch.

## Why Work Here
- **Culture**: Described as a "kindness-first" mindset with a focus on audacious goals, collaboration, and mutual support. Recognized as a *Great Place to Work* and *Best Workplace in BioPharma* (Fortune).
- **Work Model**: Hybrid, Remote, and Onsite options available depending on role. San Carlos HQ offers a hybrid schedule.
- **Total Rewards**: 100% paid health, dental, and vision insurance; 401k matching; flexible PTO and holidays; paid parental and sick leave; equity awards (stock options & RSUs); Employee Stock Purchase Plan; lifestyle spending account; mental health and wellness resources.
- **Growth & Development**: Strong emphasis on learning culture, professional advancement through coaching, and career development programs.
- **Mission-driven**: Employees are directly contributing to creating vaccines that protect every child born and every adult at risk from bacterial infections globally.

## Sources
1. [vaxcyte.com](https://vaxcyte.com/)
2. [vaxcyte.com/careers](https://vaxcyte.com/careers/)
3. [vaxcyte.com/job-listings](https://vaxcyte.com/job-listings/)
4. [vaxcyte.com/culture](https://vaxcyte.com/culture/)
5. [vaxcyte.com/pipeline](https://vaxcyte.com/pipeline/)

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