---
title: 'Manufacturing Associate I at Replimune'
canonical: 'https://feeny.ai/job/manufacturing-associate-i-replimune-framingham-a9c083cyq8ms'
type: 'job'
last_seen: '2026-09-09'
---

# Manufacturing Associate I at Replimune

- **Company:** Replimune
- **Location:** Framingham, MA
- **Employment:** full-time
- **Work type:** onsite
- **Posted:** 2026-08-27
- **Last confirmed live:** 2026-09-09
- **Apply:** https://jobs.ashbyhq.com/replimune/26e08dff-e08b-417d-8f3e-24003fd5bee2

## Job description

## Overview

Replimune’s mission is to revolutionize cancer treatment with therapies designed to activate a powerful and durable full-body anti-tumor response, boldly transforming cancer care because patient’s lives depend on it.

At Replimune, we live by our values:

United: We Collaborate for a Common Goal.

Audacious: We Are Bold.

Dedicated: We Give Our Full Commitment.

Candid: We Are Honest With Each Other.

People are at the center of everything we do, and when it comes to our employees, we make it personal. With a deep sense of purpose, a strong and evolving culture, a competitive and forward-looking total rewards program, everyone at Replimune has a unique opportunity to impact on the lives of patients, caregivers and themselves.

Join us, as we reshape the future.

Summary of job description:

The Manufacturing Associate I and II is responsible for executing the cGMP manufacturing operations to support the production of Replimune products at the Framingham, MA, facility. This individual will collaborate with multiple departments to support the manufacturing production facility. They will assist with the generation/revision of Standard Operating Procedures and associated documentation to ensure manufacturing readiness.

Key responsibilities:

- Author SOPs, batch records and deviations.
- Maintain the ability to aseptically gown and/or sterile gown as needed.
- Perform stocking and inventory of manufacturing supplies.
- Perform cleaning of process equipment and manufacturing suites.
- Ensure training requirements are kept up to date in operations being performed.
- Assemble, clean and autoclave process components and equipment.
- Prepare buffers and solutions following approved processes.
- Perform aseptic operations within Biosafety cabinets and clean room environment.
- Assist with setup and operation of single use technology production equipment for viral production, tangential flow filtration, chromatography, filtration and aseptic filling process steps.
- Become qualified and maintain qualification to perform visual inspection of final product vials.
- Follow verbal and written procedures in performing processing steps and operating production equipment.
- Perform tasks in a manner consistent with the safety policies, quality systems, and cGMP requirements and accurately completes appropriate production documentation.
- Assist with the review of completed manufacturing documentation.

Other responsibilities:

- Support validation commissioning efforts for manufacturing equipment.
- Assist with routine maintenance of production equipment.

Some occasional work may be required on weekends/holidays depending on production schedule needs.

Educational requirements:

- Bachelor’s degree and 1 to 3 years of related work experience in cGMP biopharma manufacturing preferred or
- Associate’s degree or High School Diploma and 3 to 6 years of related work experience in cGMP biopharma manufacturing.

Experience and skill requirement:

- Minimum of 1 year working in manufacturing positions in a cGMP environment.
- Experience working in one or more functional areas (Cell Culture, Purification of Drug Substance, or aseptic filling of product).
- Experience with single-use manufacturing technologies.
- Strong organizational skills and attention to detail.
- Excellent written and oral communication skills and strong team player
- Must be experienced with Microsoft Word and Excel.

Salary Range

Replimune is committed to fair and equitable compensation practices, and we strive to provide employees with total compensation packages that are market competitive. For this role, the anticipated base pay range is $79,000-$102,500. The exact base pay offered for this role will depend on various factors, including but not limited to the selected candidate’s unique set of qualifications, skills, and experience. Our current organizational needs also play a part in determining your final offer.

At Replimune, base pay is only one part of your total compensation package. The selected candidate will be eligible for an annual performance incentive bonus, new hire equity, and ongoing performance-based equity. Replimune also offers various benefits offerings, including, but not limited to, medical, dental, and vision insurance, 401k match, flexible time off, and a number of paid holidays including year-end shutdown.

## About Replimune

Replimune Group, Inc., headquartered in Woburn, MA, was founded in 2015 with the mission to transform cancer treatment by pioneering the development of a novel portfolio of oncolytic immunotherapies. Replimune’s proprietary RPx platform is based on a potent HSV-1 backbone intended to maximize immunogenic cell death and the induction of a systemic anti-tumor immune response. The RPx platform is designed to have a unique dual local and systemic activity consisting of direct selective virus-mediated killing of the tumor resulting in the release of tumor derived antigens and altering of the tumor microenvironment to ignite a strong and durable systemic response. The RPx product candidates are expected to be synergistic with most established and experimental cancer treatment modalities, leading to the versatility to be developed alone or combined with a variety of other treatment options. For more information, please visit www.replimune.com http://www.replimune.com.

We are an Equal Opportunity Employer.

## About Replimune

## Company Overview
- **One-liner**: Replimune is a clinical-stage biotech company focused on revolutionizing cancer treatment with a new class of oncolytic immunotherapies intended to activate a powerful and durable full-body anti-tumor response.
- **Entity Type**: Public (ticker not explicitly provided in search results, but company is publicly traded)
- **Headquarters**: Framingham, Massachusetts, USA (with additional locations in Woburn, MA and Oxfordshire, UK)
- **Founded**: 2015
- **Founders**: Robert Coffin, Ph.D. (Founder and Chief Scientist)

## Core Business
- **Primary industry**: Biotechnology – oncology, oncolytic immunotherapy
- **Target customers**: B2B (pharmaceutical partners) and ultimately patients through healthcare providers
- **Mission**: To ignite a systemic immune response to cancer and reshape the future of cancer care

## Products & Services
- **RPx Platform**: Proprietary, next-generation HSV-1-based oncolytic immunotherapy platform that powers all pipeline candidates.
- **RP1**: Investigational oncolytic immunotherapy for advanced melanoma (IGNYTE trial, PDUFA date April 10, 2026) and non-melanoma skin cancers; also being studied as monotherapy in organ transplant patients with skin cancer (ARTACUS trial).
- **RP2**: Investigational oncolytic immunotherapy for metastatic uveal melanoma (Phase 2/3 RP2-202 trial) and hepatocellular carcinoma (Phase 2 in combination with atezolizumab/bevacizumab).

## Market Standing
- **Valuation/Market Cap**: Not publicly available in provided sources
- **Key Metric**: Clinical-stage; no approved products yet. Key regulatory milestone: FDA action date for RP1 in advanced melanoma on April 10, 2026.
- **Notable Partners**: Bristol-Myers Squibb (supply of nivolumab), Roche (supply of atezolizumab and bevacizumab) – Replimune retains full commercial rights.
- **Growth Signals**: Completed enrollment in IGNYTE trial; confirmatory IGNYTE-3 trial underway; own 63,000 sq ft U.S. manufacturing facility in Woburn, MA enabling global commercial supply; broad pipeline across multiple solid tumor indications.

## Competitive Advantages
- **Strong IP position**: Wholly-owned, unencumbered RPx platform with broad patent protection.
- **In-house manufacturing**: Dedicated U.S. facility for commercial-scale production, reducing reliance on contract manufacturers.
- **First-mover potential**: Poised to be one of the first oncolytic immunotherapies to reach the market if RP1 gains FDA approval.
- **Full rights retained**: All partnership agreements allow Replimune to keep full commercial rights to its therapies.

## Strategic Focus
- Advancing RP1 toward FDA approval in advanced melanoma (April 2026 PDUFA date)
- Expanding pipeline into additional indications (uveal melanoma, hepatocellular carcinoma, non-melanoma skin cancers)
- Building out commercial infrastructure and manufacturing capabilities
- Exploring combination therapies with checkpoint inhibitors (nivolumab, atezolizumab)

## Why Work Here
- **Culture**: Cross-functional, collaborative, values-driven environment. Employee survey results show 92% proud to work at Replimune, 88% feel they make a positive difference, 78% would recommend the company.
- **Flexibility**: Hybrid and remote work options available depending on role; home office and mobile phone stipend provided.
- **Compensation**: New hire equity grants, generous annual bonus plans, retirement plans with substantial company match (100% vested from day one).
- **Benefits**: Medical, dental, and vision insurance 100% paid by the company.
- **Locations**: U.S. (Woburn, MA and Framingham, MA) and UK (Oxfordshire) – opportunities to work across both sites.

## Sources
1. [Replimune Homepage](https://www.replimune.com/)
2. [Replimune Careers](https://www.replimune.com/careers)
3. [Replimune About Us](https://www.replimune.com/about-us)
4. [Replimune Team](https://www.replimune.com/team)
5. [Replimune Pipeline](https://www.replimune.com/pipeline)

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