---
title: 'Meridial – Associate Scientist – In Vivo Neuroscience at Convergent Research'
canonical: 'https://feeny.ai/job/meridial-associate-scientist-in-vivo-neuroscience-convergent-research-london-k3cxeg29tvby'
type: 'job'
last_seen: '2026-10-31'
---

# Meridial – Associate Scientist – In Vivo Neuroscience at Convergent Research

- **Company:** Convergent Research
- **Location:** London, United Kingdom
- **Compensation:** £45k–£55k
- **Employment:** full-time
- **Work type:** onsite
- **Posted:** 2026-10-20
- **Last confirmed live:** 2026-10-31
- **Apply:** https://jobs.lever.co/convergentresearch/a66a2f0e-e698-4186-90b0-3394d0fd55d1

## Job description

## About Meridial

Meridial is a Focused Research Organisation (FRO) with a mission to bring connectomics into the living brain. We are building a platform for longitudinal, synapse-resolution mapping of functional neural circuitry in preclinical models. Our aim is to deploy this platform for translational projects and improve drug development outcomes for disorders of the central nervous system.

Meridial is a new not-for-profit FRO in the Convergent Research Ecosystem and funded by the Advanced Research and Invention Agency (ARIA).

## About the role

Meridial is seeking an experimental neuroscientist to join our team as Associate Scientist – In Vivo Neuroscience. This is a hands-on role. You will carry out neurosurgery, longitudinal two-photon imaging and optogenetic experiments in mice as part of Meridial’s programme to develop advanced 3D imaging and photostimulation technologies for functional mapping of neural circuits. We are looking for a scientist with strong practical and experimental skills. You should already have substantial hands-on experience with mouse neurosurgery and in vivo two-photon imaging and be motivated to develop these skills further. You will join a small Experimental Team that will grow over the coming year, and will be able to contribute to the development of protocols and workflows from an early stage. You will report to the Director of Experimental Research and will receive hands-on training and mentoring from more senior scientists in the team. You will also work closely with engineers and computational researchers across Meridial.

## Key Responsibilities

In vivo experimentation

- Perform survival neurosurgery in mice, including stereotaxic viral injections, cranial-window implantation and preparation of animals for chronic imaging and manipulation.
- Carry out high-quality in vivo two-photon imaging, including longitudinal imaging of the same animals over weeks to months.
- Run optogenetic experiments to interrogate and manipulate neural circuits.
- Support the implementation of viral and transgenic strategies for functional imaging, circuit manipulation and anatomical investigation.
- Support animal colony management, working with senior team members and animal facility staff, including tracking breeding and experimental requirements.
- Monitor preparation quality and animal welfare throughout longitudinal studies and help identify and resolve technical problems with more senior scientists.
- Maintain accurate and comprehensive records of experimental procedures and outcomes.

Method and platform development

- Follow the team’s surgical and experimental protocols and contribute to their development, optimisation and documentation as SOPs.
- Help test, evaluate and optimise new surgical, imaging and experimental approaches, including systematic evaluation of variables that affect preparation quality, reproducibility and long-term stability.
- Help test and improve microscopes, behavioural apparatus and other experimental systems in collaboration with the Engineering Team.
- Work with the Computational Team to support data acquisition, data-quality assessment and analysis, and to make sure data and metadata meet the standards needed for open sharing.

Scientific contribution and team development

- Contribute to experimental planning, interpretation and discussion within the Experimental Team.
- Communicate results, technical problems and observations clearly to colleagues across disciplines.
- Share technical expertise and good experimental practice with other team members.
- Uphold high standards of experimental rigour, reproducibility and animal welfare.

Essential Qualifications and Experience

- Degree in neuroscience, neurobiology, physiology, neuroengineering or a related discipline, or equivalent research experience.
- 3+ years’ hands-on experience with in vivo neuroscience experiments in mice.
- Demonstrated experience of survival stereotaxic surgery in mice, including intracranial viral injections and cranial-window implantation for chronic imaging.
- Substantial hands-on experience with in vivo two-photon microscopy and the acquisition of functional neural data.
- Familiarity with viral-vector and genetic approaches commonly used to study neural circuits.
- Ability to recognise experimental problems, troubleshoot procedures and contribute to method optimisation.
- Understanding of appropriate experimental controls and rigorous experimental design.
- Strong organisational skills and careful experimental record-keeping.
- Ability to work effectively as part of a multidisciplinary team and to respond constructively to scientific and technical guidance.
- If you do not already hold a UK Home Office Personal Licence covering the relevant procedures, willingness to complete the required training before starting the role. Meridial will cover the costs of the required training and licence application. Candidates trained under another national regulatory framework are very welcome.
- Strong commitment to animal welfare, the 3Rs and rigorous experimental practice.

Desirable Qualifications and Experience

- Any of the following would be particularly valuable:
- 5+ years’ practical experience with in vivo neuroscience experiments
- Longitudinal two-photon imaging of the same neural populations, cellular compartments or synaptic structures over weeks or months.
- In vivo imaging of dendrites, axons, boutons or other subcellular structures.
- Optogenetic experiments, including their design and optimisation and the combination of optical stimulation with functional neural measurements.
- All-optical circuit interrogation, such as two-photon optogenetics or holographic photostimulation.
- GRIN-lens, prism or other specialised chronic optical preparations.
- AAV, rabies-virus or other viral-vector strategies for neural labelling, imaging, manipulation or tracing, including monosynaptic rabies tracing or other transsynaptic circuit-mapping approaches.
- Histology, immunohistochemistry and confocal or fluorescence microscopy.
- In vivo or ex vivo intracellular electrophysiology, including whole-cell or targeted patch-clamp recording.
- Spatial transcriptomics, single-cell spatial profiling or related molecular approaches.
- Head-fixed behavioural experiments combined with neural imaging or manipulation.
- A current UK Home Office Personal Licence covering the relevant procedures.
- Microscope alignment, optical troubleshooting or work with custom two-photon imaging systems.
- Quantitative assessment of experimental quality and development of quality-control procedures.
- Working knowledge of Python and/or MATLAB for experimental control, data-quality assessment or analysis.
- Preparing experimental data for open sharing.

Physical Demands

- Fine motor skills for operating computers and office/lab equipment
- Ability to move light-to-moderately heavy items (typical lab supplies/equipment); may include occasional lifting/carrying with appropriate equipment (e.g., carts/dollies)

The Person We Are Looking For

You are a careful and motivated experimental neuroscientist who enjoys hands-on laboratory work and wants to build expertise in advanced in vivo methods. You take pride in producing reliable, high-quality preparations and data. When troubleshooting, you investigate the likely causes and work with more senior scientists to put solutions in place.

You are keen to learn new techniques, receptive to guidance and ready to take on more responsibility as your expertise grows. At the same time, you think critically about the experiments you perform and contribute ideas for improving methods and experimental design. You will enjoy working in a small, growing team alongside engineers and computational researchers.

Position Type / Schedule

- Start date: around March 2027.
- Full-time, 37.5 hours/week.
- Laboratory based in London, with an on-site presence of 4–5 days per week due to the experimental nature of the role.
- Longitudinal experiments and post-operative animal care will at times require work outside normal hours, including occasional weekends. This will be planned in advance and shared across the team as it grows.

Additional Information

- Application materials: CV/resume + cover letter
- 2 references will be requested during interviews
- Generous Benefits will be communicated in interviews
- For exceptional candidates, Meridial will consider visa sponsorship and relocation support.

We are an Equal Employment Opportunity employer and do not make hiring or employment decisions on the basis of race, color, religion or religious belief, ethnic or national origin, nationality, sex, gender, gender-identity, sexual orientation, disability, age, military or veteran status, or any other characteristic protected by applicable law or company policy. We strive for a diverse, healthy and safe workplace and strictly prohibit harassment of any kind.

## About Convergent Research

## Company Overview
- **One-liner**: Convergent Research is a nonprofit organization that launches and supports Focused Research Organizations (FROs) to build foundational technologies that unblock scientific progress.
- **Entity Type**: Private Nonprofit (501(c)(3))
- **Headquarters**: Palo Alto, California, United States
- **Founded**: 2021
- **Founders**: Adam Marblestone, Anastasia Gamick

## Core Business
- **Primary industry**: Scientific Research and Development Services (NAICS 5417)
- **Target customers**: B2B — scientific researchers, universities, government agencies, and philanthropic funders; operates as a "mission control" launching public-good R&D projects.
- **Mission statement**: “Spectacularly good futures are within reach, but only if we mind the gaps. Scientists need essential technologies to do the groundbreaking research all of us depend on.”

## Products & Services
Convergent Research does not sell commercial products. Instead, it incubates **Focused Research Organizations (FROs)** – time-bound, technically ambitious nonprofit efforts designed to produce high-impact public goods. Current and past FROs/projects include:

- **Cultivarium**: Developing tools for studying novel (previously unculturable) microorganisms.
- **E11 Bio (EVE Bio)**: Brain circuit mapping technologies.
- **Forest Neurotech**: Neural technology and biosensing platforms.
- **Ocean CDR Atlas**: Open-access tool for ocean-based carbon dioxide removal measurement.
- **Fundamental Development Gap Map (v1.0)**: A public web portal identifying bottlenecks holding back science.

Convergent Research provides shared operational support (legal, finance, HR, communications) across all FROs.

## Market Standing
- **Valuation/Market Cap**: Not applicable (nonprofit).
- **Annual Revenue (FY2024)**: **$72.4 million** (ProPublica IRS filing). Total revenue for FY2024 was $100.1 million.
- **Total Grant Funding Received**: At least $25.1 million from Vanguard Charitable, $9.5 million from Probabilistic Computing Foundation, $8 million from The Eric and Wendy Schmidt Fund for Strategic Innovation (latest filings).
- **Total Funding Raised**: ~$2 million in disclosed grants (led by Alfred P. Sloan Foundation in 2023); the vast majority comes from additional major philanthropic gifts not categorized as single-investor rounds.
- **Notable Partners/Funders**: Advanced Research and Intervention Agency (ARIA, UK), Alfred P. Sloan Foundation, The Eric and Wendy Schmidt Fund for Strategic Innovation, Vanguard Charitable, Probabilistic Computing Foundation.
- **Growth Signals**: 164 employees (as of latest CauseIQ data, up from ~23 on LinkedIn); headquarter presence in Palo Alto, Cambridge (MA), and Boulder (CO); expanded into the UK via a collaboration with ARIA (“FROST UK”); 15 active job postings with 25% month-over-month posting growth.

## Competitive Advantages
- **Novel institutional model**: Focused Research Organizations (FROs) fill a gap between traditional academia and for-profit startups — targeted, time-boxed, public-good missions.
- **Lean central infrastructure**: Shared operational support lets FRO scientists focus purely on technical breakthroughs, avoiding administrative overhead.
- **High-caliber scientific network**: Leaders include senior scientists from MIT, Caltech, King’s College London, and CMU as grantees/collaborators.
- **Access to major philanthropic capital**: Partners with some of the largest climate and science foundations globally.

## Strategic Focus
- **Geographic expansion**: Formal partnership with ARIA in the UK to launch FROs abroad (“FROST UK”).
- **Gap mapping**: Releasing and refining the Fundamental Development Gap Map to systematically identify the biggest bottlenecks in science.
- **Scaling the FRO model**: Adding new FROs in ocean CDR, neuroscience, and molecular engineering; hiring Founders in Residence to spin up new efforts.
- **Public data as product**: Committed to releasing open datasets and protocols (e.g., drug–target assay data, Lean proof library) as public goods.

## Why Work Here
- **Mission-driven**: Direct, hands-on impact on solving foundational scientific bottlenecks rather than incremental product improvements.
- **Culture**: Described as “mission control” — fast-paced, collaborative, technical. Leadership emphasizes pushing high-risk, high-reward projects.
- **Locations**: On-site positions in Palo Alto (CA), Cambridge/Boston (MA), and Boulder (CO). Some roles are US- or UK-based.
- **Team composition**: Small, senior-heavy centralized team (~20 core staff in Palo Alto) plus larger distributed FRO project teams (~164 total organization-wide). Significant cross-functional work across legal, finance, operations, and science.
- **Typical roles**: Postdoctoral Research Scientists, Research Associates, Biosensing Engineers, Finance/Operations Managers, General Counsel.
- **Compensation transparency (IRS filing)**: CEO Adam Marblestone — $431,025; President Anastasia Gamick — $360,495; competitive nonprofit scientific salaries.
- **Notable perks**: Working with world-class scientists and funders; contributions to genuinely public-good science; tax-deductible donation eligible organization.
- **Remote/hybrid**: Mostly on-site (Boulder, Palo Alto, Cambridge); limited remote possibilities depending on role.

## Sources
1. [convergentresearch.org](https://www.convergentresearch.org/)
2. [jobs.lever.co/convergentresearch](https://jobs.lever.co/convergentresearch)
3. [linkedin.com/company/convergent-research](https://linkedin.com/company/convergent-research)
4. [causeiq.com – Convergent Research](https://www.causeiq.com/organizations/convergent-research,883013217/)
5. [projects.propublica.org – Convergent Research Inc](https://projects.propublica.org/nonprofits/organizations/883013217)

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