---
title: 'Principal Central Monitor / Risk Manager at Precision for Medicine'
canonical: 'https://feeny.ai/job/principal-central-monitor-risk-manager-precision-for-medicine-bengaluru-pnk0anqsf4vk'
type: 'job'
last_seen: '2026-09-14'
---

# Principal Central Monitor / Risk Manager at Precision for Medicine

- **Company:** Precision for Medicine
- **Location:** Bengaluru, India
- **Posted:** 2026-08-14
- **Last confirmed live:** 2026-09-14
- **Apply:** https://job-boards.greenhouse.io/pfm/jobs/6144054004

## Job description

Position Summary:

The Principal Central Monitor (Risk Manager) serves as a strategic leader in driving data integrity, patient safety, and operational excellence across clinical development programs through advanced centralized monitoring and risk-based quality management (RBQM). This role is accountable for shaping and executing enterprise-wide RBQM strategies, leading complex risk assessments, and defining key risk indicators (KRIs) in collaboration with senior functional leaders.  Operating at the highest level of subject matter expertise, the Principal Central Monitor oversees the design and implementation of centralized statistical monitoring frameworks, leads RBQM governance forums, and ensures proactive risk detection and mitigation across portfolios. This role provides strategic oversight for high-impact studies and therapeutic areas, guiding cross-functional teams through data-driven decision-making and continuous improvement.  In addition to managing escalations and complex data review activities, the Principal Central Monitor mentors senior & junior colleagues, contributes to global process innovation, and plays a key role in shaping policies, tools & technologies that enhance centralized monitoring capabilities organizationally.

Essential functions of the job include but are not limited to:

- Lead Development of RBQM Plan: Collaborate with cross-functional teams to design and implement comprehensive RBQM plans tailored to each study's needs - including identification of critical data & process, definition of KRIs & QTLs and centralized monitoring approach
- Study Risk Assessment: Conduct thorough risk assessments for clinical studies, identifying potential issues and developing mitigation strategies, in consultation with functional team leads and PM
- Advanced Centralized Statistical Monitoring: Design and oversee the implementation of advanced centralized statistical monitoring frameworks. Interpret complex data patterns, lead root cause analyses, and drive data-driven decision-making to enhance study quality and compliance, in collaboration with functional team leads and PM
- RBQM Meetings: Lead facilitation monthly RBQM meetings, bringing together key stakeholders to review and discuss study data, findings, action plans and coordination of data cleaning activities to support study deliverables. Drive the review of key risk indicators (KRIs), data trends, and issue resolution plans. Provide expert guidance on data cleaning prioritization to meet critical study milestones.
- Data Quality Assurance and Oversight: Ensure the highest standards of data quality and integrity through proactive monitoring and timely interventions. Mentor teams on proactive data monitoring techniques and lead initiatives to continuously improve data integrity and efficiency.
- Collaboration: Work closely with clinical operations, data management, biostatistics, and other departments to support proactive oversight and management and data cleaning for studies
- Reporting: Prepare detailed reports and presentations on monitoring activities, findings, and recommendations for sponsors and study teams. Translate complex monitoring insights into actionable recommendations that drive strategic decisions and study success.
- Operational Insights: Oversee operational study metrics, including data entry trends, SDV backlog, site health trending and proactively communicate issues to study team members to drive towards resolution & proactive remediation
- Mentor and Support Junior Colleagues: Act as a mentor to more junior Central Monitors - sharing best practices, lessons learned, etc. to improve team performance
- Sponsor Engagement and Communications: lead discussions with Sponsors around risk management and proactive data cleaning

Qualifications:

Minimum Required:

- Bachelor’s Degree in a relevant field (life sciences, statistics, data management, clinical operations) or relevant/equivalent combination of education, training, and experience
- Minimum 10+ years experience in clinical monitoring, clinical trial management or equivalent
- Working knowledge of ICH GCP guidelines and the clinical development process

Other Required:

- Highly effective oral and written communication skills with the ability to communicate effectively with project team members
- Excellent organizational and time management skills
- Excellent written and spoken English, including strong grammar & scientific vocabulary skills
- Ability to work in a team or independently as required
- Strong understanding of RBQM principles and methodologies.
- Demonstrated ability to learn how to extract pertinent information from protocols, electronic study data systems, clinical systems, dashboards, and to leverage these data to assess risk
- Proficiency in statistical analysis and data monitoring tools.
- Detail-oriented with strong analytical and problem-solving skills
- Demonstrated experience with integrated risk planning & management
- Ability to mentor junior team members

Preferred:

- CRO experience as a Central Monitor

Skills:

- Statistical analysis and data monitoring
- Risk assessment and mitigation
- Report writing and presentation
- Collaboration and teamwork

Any data provided as a part of this application will be stored in accordance with our [Privacy Policy.](https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.precisionmedicinegrp.com%2Fprivacy-policy%2F&data=05%7C01%7Czeta.larcon%40precisionmedicinegrp.com%7Cb58fe8b0c3ea4dd2e79d08db5bd09a25%7Cb71ff3f628164ca8a9b938f820f91ad1%7C0%7C0%7C638204723732367131%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=9DgboiHTFPrNYVhdKhyfdwVyNYwUvZbP%2FroLdWIIfxw%3D&reserved=0) For CA applicants, please also refer to our [CA Privacy Notice](https://nam12.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.precisionmedicinegrp.com%2Fca-applicants-privacy-notice%2F&data=05%7C01%7Czeta.larcon%40precisionmedicinegrp.com%7Cb58fe8b0c3ea4dd2e79d08db5bd09a25%7Cb71ff3f628164ca8a9b938f820f91ad1%7C0%7C0%7C638204723732367131%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&sdata=tfAqqMZsG%2B11IchL45HFFVbfECCkYqQpNr0PQxrMFJU%3D&reserved=0).

Precision Medicine Group is an Equal Opportunity Employer. Employment decisions are made without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status or other characteristics protected by law.

If you are an individual with a disability and require a reasonable accommodation to complete any part of the application process or are limited in the ability or unable to access or use this online application process and need an alternative method for applying, you may contact Precision Medicine Group at myHR@precisionmedicinegrp.com.

Recruitment Fraud Warning: Please be aware that fraudulent individuals and websites may impersonate Precision Medicine Group or its affiliates and attempt to obtain personal, financial, or banking information through fake job postings or employment offers. Precision Medicine Group will never request payment, banking details, or other sensitive financial information as part of the recruitment process. If you believe you have been targeted by a recruitment scam, we encourage you to report the incident to your local law enforcement authorities, consumer protection agency, or relevant cybercrime reporting organization in your country. Please also notify us at myHR@precisionmedicinegrp.com so we can investigate and take appropriate action.

## About Precision for Medicine

## Company Overview
- **One-liner**: Precision for Medicine is a global clinical research organization (CRO) and laboratory services provider specialized in accelerating the development of precision therapies for oncology, rare disease, and other complex conditions.
- **Entity Type**: Private – subsidiary of Precision Medicine Group (a private holding company)
- **Headquarters**: Not explicitly stated in sources; likely around the Washington D.C./Maryland area (Precision Medicine Group HQ is in Bethesda, MD). The company operates globally with labs in North America and Europe.
- **Founded**: 2012 (company began), but the team has over 25 years of clinical trial experience
- **Founders**: Not publicly disclosed on provided sources; leadership includes a founder role but name not given.

## Core Business
- **Primary industries**: Contract Research Organization (CRO) services, central laboratory services, biospecimen solutions, data intelligence for clinical development.
- **Target customers**: Biotechnology and pharmaceutical companies developing precision medicines, especially in oncology and rare disease (B2B, mid-to-large pharma).
- **Mission/purpose**: “Bringing life-changing therapies to patients by integrating laboratory expertise, clinical trial excellence, and data intelligence to deliver critical insights into patient biology.”

## Products & Services
- **Global CRO Services**: Full-service clinical trial management with a focus on early- and late-phase development, regulatory support, project management, and site startup. Over 75% of trials are in oncology.
- **Global Laboratory Services**: Translational and biomarker sciences, including specialty labs for genomics, flow cytometry, molecular diagnostics, and central lab testing. Operates 5 specialty labs in the US and Europe.
- **Biospecimens**: Access to over 11 million tissue, cellular, and biofluid specimens for research.
- **Data Intelligence**: AI-enabled data ecosystem for sample management, biomarker analysis, biostatistics, and decision support (includes a conversational AI virtual assistant).
- **Diagnostics and Companion Diagnostics (CDx)**: Development and commercialization of diagnostic tests aligned with therapies.

## Market Standing
- **Valuation / Market Cap**: Not publicly disclosed (part of private Precision Medicine Group).
- **Key Metric**: ~3,500 employees; 2,500+ clinical trial and lab projects; 70% of clinical trials in oncology; 25+ years of combined experience.
- **Notable Investors/Partners**: Sources mention “$30B in investments raised for biotech in the last 5 years” (general biotech investment, not specific to Precision). No specific lead investors listed; backed by private equity (Precision Medicine Group is owned by institutional investors).
- **Growth Signals**: Awarded the 2025 Fierce Biotech CRO Award for Innovative Solutions in Drug Development. Active hiring with 129 job openings globally (as of July 2026). Strong remote/hybrid work options across many roles.

## Competitive Advantages
- **Integrated CRO + Lab + Data**: One organization covering the full spectrum from biospecimens to late-phase trials, reducing inefficiencies of working with separate vendors.
- **Specialization in complex indications**: Deep expertise in oncology and rare disease, where protocols are highly complex.
- **Right-sized CRO model**: Assigns employees to no more than 2–3 trials at a time, offering more attention than large “Big Five” CROs (positioned as “antidote to Big Five Fatigue”).
- **AI-enabled data intelligence**: Unified ecosystem with conversational AI to extract insights from siloed data.

## Strategic Focus
- Continue expanding capabilities in precision medicine development, particularly in early-phase oncology and rare disease.
- Leverage data intelligence and AI to improve trial efficiency and patient matching.
- Scale global clinical operations (recent push into Asia Pacific, Latin America, and Eastern Europe).

## Why Work Here
- **Culture**: Employee-driven mission “to help patients get access to innovative treatments.” Collaboration across functions is emphasized, with a focus on complex and impactful therapies.
- **Work environment**: Strong remote/hybrid options – job postings span remote roles in the US, Canada, Europe, Asia, and Latin America. Offices and labs exist in multiple countries.
- **Perks & growth**: Not explicitly detailed, but the company invests in career development (e.g., roles from CRA to Director level). 25 years of history and a growing global footprint indicate stability and upward mobility.
- **Engineering & science culture**: Teams include clinical scientists, data engineers, lab professionals, and operations – a blend of deep science and tech.

## Sources
1. [Precision for Medicine – Homepage](https://www.precisionformedicine.com/)
2. [Precision for Medicine – Our Story](https://www.precisionformedicine.com/about-us/our-passion/)
3. [Precision for Medicine – Leadership](https://www.precisionformedicine.com/about/leadership)
4. [Precision for Medicine – Careers (Greenhouse)](http://job-boards.greenhouse.io/pfm)
5. [Precision for Medicine – LinkedIn](https://www.linkedin.com/company/precision-for-medicine)

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