---
title: 'Principal Design Engineer, Analog Mixed-Signal (AMS) at Epia Neuro'
canonical: 'https://feeny.ai/job/principal-design-engineer-analog-mixed-signal-ams-epia-neuro-alameda-dt3jvye9bk9n'
type: 'job'
last_seen: '2026-11-02'
---

# Principal Design Engineer, Analog Mixed-Signal (AMS) at Epia Neuro

- **Company:** Epia Neuro
- **Location:** Alameda, CA
- **Compensation:** $225k–$280k
- **Employment:** full-time
- **Work type:** onsite
- **Posted:** 2026-09-25
- **Last confirmed live:** 2026-11-02
- **Apply:** https://jobs.ashbyhq.com/epianeuro/5f3ddd46-492b-4210-b5ae-4aa534bbb81c

## Job description

## About Us

Epia Neuro is a neural technology company developing intent-driven systems designed to restore function and independence for people living with neurological conditions. Its platform integrates implantable neural interfaces, adaptive algorithms, and assistive devices to translate neural intent into real-world action. The company's initial focus is stroke-related motor impairment, with expansion into cognitive decline and other neurological disorders, focusing on long-term solutions for the growing aging population.

## The Role

We're looking for a Principal Design Engineer, Analog Mixed-Signal (AMS) to own the custom analog/mixed-signal ASIC at the heart of our implantable system. You'll own the chip architecture end to end: turning system requirements and early design work into the blueprint the team builds from - a complete design specification and implementation plan, revised wherever the requirements or silicon reality demand it. You'll personally design the most critical analog blocks at transistor level, direct the rest, and carry the chip through tapeout and silicon bring-up. On a small team, you'll make the calls a larger company would split across several people, and you'll own the results.

## What You'll Do

- Own the chip-level architecture: turn system requirements and our existing architecture concept into a written, reviewable design specification and implementation plan
- Document your work continuously, including design choices, tradeoffs, and verification results, and treat documentation as a first-class deliverable
- Personally design the most critical low-noise, ultra-low-power analog and mixed-signal blocks for an implantable device (e.g., neural recording front-ends, ADCs, bandgap references, clocks, power management), and direct the design of the rest across the team and partners
- Run the full verification loop: pre- and post-layout simulation, corners and Monte Carlo, and SOA/reliability/aging checks appropriate for a long-life implant
- Build behavioral models (Verilog-A/AMS, SystemVerilog) to support top-level and mixed-signal verification
- Drive process/foundry, IP, and vendor decisions (foundry, layout, OSAT/packaging, test services)
- Lead design reviews, mentor engineers, and set documentation and design-reproducibility standards for the team
- Work closely with layout, digital, system, and test engineers, and own post-silicon bring-up and debug in our lab

## Qualifications

- 10+ years of hands-on experience owning AMS IC designs, with multiple tapeouts carried through to silicon validation
- Lead the architecture or analog specification of at least one chip from concept to silicon
- Deep transistor-level expertise in low-noise and/or ultra-low-power precision analog
- Strong reliability-first design approach: ESD, device breakdown/SOA, aging, and yield
- Fluency in the Cadence Virtuoso/Spectre flow and a Linux-based, scripted, version-controlled design environment
- BS, MS, or PhD in Electrical Engineering or a related field (MS or PhD preferred)

## Nice to Have

- ASIC design for biomedical, implantable, or neural-interface applications
- High-voltage or specialty process experience (e.g., BCD, SOI)
- Experience working directly with foundries and OSATs, including process selection and packaging decisions
- Familiarity with medical-device development under design controls (e.g., ISO 13485 / FDA QMSR) or active-implant standards (e.g., ISO 14708)
- Experience with open-source IC tools or flows
- Prior experience at an early-stage company or as a first/senior analog hire

## How We Work

- We are intentional. We prioritize and are thoughtful about how we use others' time.
- We care for others. We prioritize safety both for patients and one another.
- We own outcomes, not just tasks. Our work demands the highest standards because it impacts real patients and real lives.
- Humility is a strength. We are honest about what we know and what we don't know. Getting it right matters more than being right.

Location This role is based in Alameda, CA, on site 4 days a week - hands-on lab access and bring-up are part of the job.

## Benefits

- Competitive base salary with equity
- 100% of healthcare coverage for you and your dependents
- Generous vacation policy
- Paid parental leave
- Work from our waterfront office in Alameda, CA, with access to collaborative spaces and labs

## About Epia Neuro

## Company Overview
- **One-liner**: Epia Neuro is developing a minimally invasive, implantable brain-computer interface system that translates neural intent into real-world action, starting with stroke recovery and expanding to cognitive decline and other neurological disorders.
- **Entity Type**: Private (stealth-stage startup – officially launched April 2026; no funding round disclosed)
- **Headquarters**: Alameda, California, United States
- **Founded**: 2026 (official launch); development began approximately 2021
- **Founders**: Michel Maharbiz, Ph.D. (CEO) and Gil Mandelbaum, Ph.D. (CTO & Science Officer)

## Core Business
- **Primary industry**: Medical Equipment Manufacturing / Neurotechnology (Brain-Computer Interfaces)
- **Target customers**: B2B – hospitals, neurosurgery departments, rehabilitation clinics; B2C – stroke survivors and individuals with movement or cognitive impairments
- **Mission statement**: “To address the gap between intent and action” – building neurotechnology that gives back the freedom to move and think

## Products & Services
- **Implantable Brain Interface**: A proprietary neural interface that captures signals without piercing the dura. Designed for sub-hour implantation by any neurosurgeon. Supports both sensing (reading neural intent) and stimulation (closed-loop therapy). Rechargeable non-invasively via headset and built with a cradle system for future upgrades without additional invasive surgery.
- **Decoder System / Closed-Loop Intelligence**: Adaptive algorithms that interpret neural signals in real time and adjust stimulation parameters continuously, building a personalized “longitudinal map” of each patient’s neural activity.
- **Wearable Grip Assist**: A lightweight, daily-use motor prosthetic that helps stroke survivors grasp, hold, and release objects. Developed with input from survivors, advocates, and clinicians.
- **Platform Expansion**: The stroke therapy acts as a proof-of-concept for treating epilepsy, Parkinson’s disease, cognitive decline, and other neurological conditions through combined sensing and deep brain stimulation.

## Market Standing
- **Valuation**: Not publicly available (company is pre‑revenue and privately held)
- **Key Metric**: Total funding – not publicly disclosed (company is “totally independent” according to Inside BCI, with no disclosed investors)
- **Notable Investors/Partners**: Institutional advisors include Mass General Hospital, Lenox Hill Hospital (first‑in‑human trial site), Beth Israel Deaconess Medical Center, and Harvard Medical School. No formal investor list has been released.
- **Growth Signals**: Official launch April 2026; plans for first‑in‑human system demonstrations at Lenox Hill Hospital (New York) later in 2026; headcount of 24 employees (as of mid‑2026) with active hiring across engineering, electrical systems, and clinical roles; increasing LinkedIn follower base (1,459) and strong social engagement on launch posts.

## Competitive Advantages
- **Minimally Invasive**: Implant sits entirely within the skull, no breach of dura – reduces surgical risk compared to penetrating cortical BCIs.
- **Quick Procedure & Scalability**: Designed for sub‑hour implantation by any neurosurgeon, facilitating broad clinical adoption.
- **Upgradable & Long‑Life**: Cradle system allows device upgrades without additional surgery. Rechargeable headset eliminates the need for battery‑replacement surgeries.
- **Closed‑Loop Read/Write**: Both senses neural signals and delivers stimulation, enabling adaptive, real‑time therapy (beyond read‑only BCIs).
- **Platform Approach**: Stroke motor recovery is the entry point; the same hardware/software stack can address epilepsy, Parkinson’s, and cognitive decline, creating a large addressable market (estimated >$5B US opportunity for stroke alone).

## Strategic Focus
- **Near‑term**: Complete first‑in‑human demos, prepare for regulatory submissions (FDA), and scale the engineering team.
- **Medium‑term**: Leverage stroke clinical data to build evidence for cognitive decline and other indications; broaden the implant’s deep brain stimulation capabilities.
- **Long‑term**: Become a standard‑of‑care neural interface platform for a wide range of neurological disorders, with an emphasis on “widely accessible” neurotechnology.

## Why Work Here
- **Mission‑Driven**: Employees directly contribute to restoring independence for stroke survivors and people with neurological conditions (“If you want your work to restore independence for millions of people, we want to hear from you.”)
- **Cutting‑Edge Technology**: Work on the frontier of medical BCI, combining implantable hardware, adaptive AI, and real‑time neural decoding.
- **Early‑Stage Culture**: As a recently launched startup (~24 employees), you’ll have outsized impact on product design, clinical strategy, and company trajectory.
- **Multidisciplinary Team**: Composed of engineers, neuroscientists, and operations leaders from iota Biosciences, UC Berkeley, Harvard, and industry.
- **Work Style**: Likely in‑office in Alameda, CA (with a small presence in Canada); no formal remote/hybrid policy announced yet.
- **Active Hiring**: Open roles include Staff/Principal Electrical Systems Engineer, Analog Mixed‑Signal Design Engineer, and other technical positions (see careers page).

## Sources
1. [epianeuro.com](https://www.epianeuro.com/)
2. [businesswire.com](https://www.businesswire.com/news/home/20260402282679/en/Epia-Neuro-Launches-to-Develop-Intent-Driven-Neural-Technology-to-Restore-Function-After-Stroke-and-Address-Cognitive-Decline)
3. [linkedin.com/company/epia-neuro](https://www.linkedin.com/company/epia-neuro)
4. [insidebci.com](https://insidebci.com/news/2026-04-22-maharbiz-launches-epia-neuro-stroke-focused-bci-built-for-lifelong-assistive-use/)

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