---
title: 'Principal Investigator (MD/DO) - Respiratory Clinical Trials at Hawthorne Health'
canonical: 'https://feeny.ai/job/principal-investigator-md-do-respiratory-clinical-trials-hawthorne-health-tz8a24ppapnk'
type: 'job'
last_seen: '2026-09-10'
---

# Principal Investigator (MD/DO) - Respiratory Clinical Trials at Hawthorne Health

- **Company:** Hawthorne Health
- **Location:** Mcallen, TX
- **Compensation:** $150–$250/hr
- **Employment:** contract
- **Work type:** hybrid
- **Posted:** 2026-04-09
- **Last confirmed live:** 2026-09-10
- **Apply:** https://jobs.lever.co/hawthorne-health/f69cedba-edd3-4b02-b76b-984598b5eacb

## Job description

## About Us

Hawthorne Health is a leading community site network and home research visit solution provider, with 20+ sites and more than 2,000 research experienced healthcare professionals across the U.S. Hawthorne leverages convenient, trusted, healthcare locations, identified patient data, and intelligent technology to accelerate patient access, improve retention, and reduce study costs. By embedding high-quality research within local communities, Hawthorne makes clinical trials more accessible and convenient for patients. Our community-based model shortens timelines and helps bring better treatments to market, faster.

## About the Role

Hawthorne Health is seeking an experienced Principal investigator (MD/DO) for a part-time, 1099 role. Candidates should have prior experience as a PI or Sub-I on sponsor-initiated clinical trials. This role will lead Respiratory trials including Asthma within our growing, community-based site network—built to make research efficient, patient-friendly, and investigator-supported.

## Responsibilities

- Accurately document findings and contribute to ongoing clinical trials, registries, or research protocols as applicable.
- Oversee and manage all aspects of clinical trials conducted at the research site, ensuring adherence to the study protocol, Good Clinical Practice (GCP), ICH guidelines, and all applicable regulatory requirements.
- Lead and supervise the clinical research team, including sub-investigators, study coordinators, and other site staff.
- Delegate study-related duties appropriately to qualified personnel and ensure proper training and oversight.
- Conduct remote review of patient assessments, including physical exams, medical histories, and eligibility screenings, to ensure appropriate participant enrollment.
- Review and interpret laboratory results, ECGs, and other diagnostic tests.
- Make critical medical decisions regarding participant care, adverse events, and protocol deviations.
- Ensure accurate, complete, and timely collection and documentation of all study data.
- Communicate effectively with sponsors, Contract Research Organizations (CROs), Institutional Review Boards (IRBs), and regulatory authorities.
- Manage investigational product accountability, storage, and administration according to protocol and with the help of the on-site IP team.
- Participate in site initiation visits, monitoring visits, audits, and inspections.
- Maintain continuous medical education and stay current with advancements in clinical research and relevant therapeutic areas.

## Requirements

- Must be an MD with experience leading at least three sponsor initiated trials as a PI or Sub-I.
- Current, unrestricted medical license.
- Experience with respiratory indications in clinical trials and/or in a clinical setting.
- Demonstrated in-depth knowledge of ICH-GCP guidelines, FDA regulations, and other relevant ethical and regulatory requirements for clinical research.
- Proven leadership and team management skills.
- Excellent clinical judgment and decision-making abilities.
- Strong verbal and written communication skills in English, with the ability to present complex information clearly and concisely.
- Exceptional organizational skills and meticulous attention to detail.
- Ability to manage multiple complex studies simultaneously and prioritize tasks effectively.
- Commitment to ethical conduct and patient safety.

Location

- This role requires on-site presence approximately twice to four times per month for key visits (or more, depending on study needs), with additional oversight responsibilities performed remotely (approximately 3–5 hours per week).
- Preference is for Investigator to live within 1.5 hours driving distance of the site.

Hawthorne Health is transforming the clinical trial landscape through an innovative site model that integrates research into community-based settings like local pharmacies. By meeting patients where they already receive care, we are improving access, strengthening trust, and driving more inclusive and efficient trials. We welcome the opportunity to connect with individuals interested in being part of this evolving model.

## About Hawthorne Health

## Company Overview
- **One-liner**: Hawthorne Health brings clinical trials directly to patients in their communities by combining innovative technology with dedicated medical professionals.
- **Entity Type**: Private (Series A funded)
- **Headquarters**: Walnut Creek, California, United States
- **Founded**: 2015
- **Founders**: Not publicly available

## Core Business
- **Primary industry**: Clinical Research / Healthcare Services (Research Services)
- **Target customers**: B2B (pharmaceutical sponsors, CROs) and B2C (patients)
- **Mission statement**: "To make clinical trials accessible and convenient for every patient and deliver meaningful and high-quality clinical assessments for investigators." [hawthornehealth.com/about/](https://hawthornehealth.com/about/)

## Products & Services
- **Community Site Network**: 75+ locations across the U.S. where patients can participate in clinical trials within trusted community healthcare settings.
- **Mobile Clinical Services**: GCP-trained nurses and sonographers (echo, pediatric, adult) who conduct visits at patients’ homes or local pharmacies, covering all 50 states.
- **Hybrid Trial Platform**: Intelligent technology that orchestrates distributed touchpoints, automates complex logistics, and manages a single CTA and project manager for sponsors, enabling cost structures comparable to site-only trials. [linkedin.com/company/hawthornehealth](https://linkedin.com/company/hawthornehealth)

## Market Standing
- **Valuation/Market Cap**: Not disclosed (private)
- **Key Metric**: Annual Revenue $4.1M (latest); Total Funding $23.1M (Seed $3M in 2017, Convertible Notes, Series A $20M in June 2021)
- **Notable Investors/Partners**: Series A had 3 investors (names not publicly listed); partners include over 40 study sponsors and 2,000 GCP-trained nurses.
- **Growth Signals**: Headcount of 130 (+19.3% YoY); 4,000+ "Hawthorne Heroes" (network of clinicians); 8M+ data points collected; active in 50 states; 75+ community locations; 46 active job postings (+4,500% YoY growth in postings). [hawthornehealth.com/about/](https://hawthornehealth.com/about/)

## Competitive Advantages
- **Community-first model**: Trials are embedded in local pharmacies and clinics, reducing patient burden and improving retention.
- **Hybrid cost efficiency**: Delivers hybrid trials at cost structures comparable to traditional site-only trials, with one accountable partner from startup to closeout.
- **Scale and reach**: 2,000 GCP-trained nurses covering all 50 states, 75+ sites, and 30+ investigators across 11+ therapeutic areas.
- **Technology-driven orchestration**: Proprietary platform automates scheduling, data collection, and compliance, making distributed trials scalable.

## Strategic Focus
- **Expansion of community network**: Growing the number of community sites and investigator partnerships.
- **Hybrid trial adoption**: Pitching hybrid models as a cost-effective, patient-centric alternative to traditional site-only or fully decentralized trials.
- **Technology investment**: Continued development of AI tools (including in hiring) and data analytics to improve patient enrollment and protocol compliance.

## Why Work Here
- **Purpose-driven culture**: Employees are motivated by the mission to save lives and make clinical research accessible to all.
- **Collaborative environment**: Combines medical professionals, entrepreneurs, developers, and designers to solve complex healthcare challenges.
- **Remote/hybrid flexibility**: Roles vary – sonographer positions are on-site, while Principal Investigator roles offer hybrid arrangements.
- **Growth opportunities**: Rapid headcount growth (19% YoY) and a large number of open positions across medical, operations, and technology departments.
- **Innovation focus**: The company uses AI to support hiring and trial logistics, signaling a forward-thinking engineering culture. [jobs.lever.co/hawthorne-health](https://jobs.lever.co/hawthorne-health)

## Sources
1. [jobs.lever.co/hawthorne-health](https://jobs.lever.co/hawthorne-health)
2. [hawthornehealth.com/about/](https://hawthornehealth.com/about/)
3. [hawthornehealth.com/careers/](https://hawthornehealth.com/careers/)
4. [linkedin.com/company/hawthornehealth](https://linkedin.com/company/hawthornehealth)
5. [hawthornehealth.com/leadership/](https://hawthornehealth.com/leadership/)

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