--- title: 'Principal Product Designer at Prolaio' canonical: 'https://feeny.ai/job/principal-product-designer-prolaio-chicago-4vmzt3n9jr38' type: 'job' last_seen: '2026-09-09' --- # Principal Product Designer at Prolaio - **Company:** Prolaio - **Location:** Chicago, IL - **Posted:** 2026-08-05 - **Last confirmed live:** 2026-09-09 - **Apply:** https://job-boards.greenhouse.io/prolaio/jobs/5374113008 ## Job description Who Are We? Prolaio believes that continuous learning and collaboration can make a significant difference in how heart care is administered. We are creating smarter ways to address heart disease and heart risks by uniting patients, care teams, and researchers on a secure, technology-enabled platform that drives clinical innovation and offers a path towards better patient outcomes. This is precision cardiology, and we know it’s within reach. What Will You Do? The Overview The Principal Product Designer to own the end-to-end design of our products — from early-stage discovery through polished, production-ready interfaces. This is a foundational hire at a critical stage of growth. You will be the design voice in the room: following standards, collaborating with Product & Engineering, and delivering work that meets both the needs of clinicians and patients. This individual contributor role is ideal for a seasoned generalist who is comfortable with ambiguity and confident in using their craft to create clarity. A strong candidate will be equally skilled in gathering requirements, building information architecture, and crafting high-fidelity UI. The Specifics - Define and drive long-term product vision and design strategy for multiple products. Lead complex, ambiguous design problems from conceptual exploration through detailed execution. - Partner with Product Manager and Engineering teams to conduct workshops, feature definition, and stakeholder management - Collaborate with clinical, regulatory, and legal teams to translate user needs into design artifacts and specifications - Design high-fidelity mockups and interactive prototypes for user research and development handoff - Update organization regularly on product design progress. - Represent the design perspective for broad, non-technical audience Why Prolaio? - Impactful Work: You will join in the fight against heart failure (HF) and hypertrophic cardiomyopathy (HCM) with the goal of extending and saving the lives of our patients while also being at the forefront of changing the healthcare industry through technology. - Innovative Environment: You will be part of an organization doing something that’s never been done before. - Professional Growth: You will join a growing team and have a substantial impact on our daily and future operations with the opportunity to continuously learn and grow. - Collaborative Team: You will be part of a team of collaborative, curious, and committed individuals focused on the collective good, inclusiveness, scientific excellence, and advancing digital health for cardiology. Who You Are? - 7+ years of product or UX/UI design experience, including 3 years in a senior or principal-level role - Portfolio demonstrating end-to-end of complex product design, ranging from long term product vision, to detailed execution - Hands-on experience designing for regulated industries, preferably medical devices, health IT, or clinical software - Strong organization, written, and verbal communication skills, including ability to document design rationale and detailed specifications. - Working understanding of product management and development processes, with demonstrated experience collaborating with those disciplines ## Why You’ll Love Working Here - Meaningful Compensation: Competitive salary, performance bonus, and equity so you can share in what we build. - Great Health Coverage: Medical, dental, and vision plans with multiple options and strong company contributions. - Flexible Spending Perks: HSA, FSA, commuter benefits, and a $1,200 annual Lifestyle Spending Account to support wellness, commuting, family needs, and more. - Time to Recharge: Generous paid time off, sick leave, and company holidays. - Family-First Benefits: Paid parental leave, caregiver leave, and support for growing families. - Security & Peace of Mind: Company-paid life insurance and short- and long-term disability coverage. - Plan for the Future: 401(k) plan to help you build long-term financial security. - Care When You Need It: Easy access to telehealth and optional supplemental coverage for life’s unexpected moments. Starting Salary is at $154,000.00 (Exact Compensation may vary based on skills, experience, and location) ## About Prolaio ## Company Overview - **One-liner**: Prolaio is a clinical intelligence company that uses a connected platform of near real-time heart data and AI to help patients, clinicians, and researchers manage cardiovascular conditions and accelerate the development of new therapies. - **Entity Type**: Private (startup; combined with Kardigan in 2025) - **Headquarters**: Chicago, Illinois, USA - **Founded**: 2022 - **Founders**: Derek Evans (Co-Founder); other founders not publicly disclosed. ## Core Business - **Primary industry**: Healthtech / Cardiovascular Clinical Intelligence - **Target customers**: B2B (healthcare providers, clinical researchers, pharmaceutical companies) and B2C (patients with cardiovascular conditions like heart failure and hypertrophic cardiomyopathy) - **Mission statement**: "Transform real‑world heart data into faster discovery today and precision care for functional cures tomorrow." ## Products & Services - **Prolaio Clinical Intelligence Platform**: An integrated platform that collects continuous, high‑density heart data (via a mobile relay device and on‑body sensors) and applies proprietary AI algorithms to generate measures of cardiovascular function. The insights are used to improve clinical decision-making, monitor patients remotely, and support clinical trials for new therapies. *Type*: SaaS + Medical Device (cloud analytics, AI algorithms, data relay hardware) ## Market Standing - **Valuation / Funding**: Not publicly available. - **Key Metrics**: - 4M+ hours of on‑body patient data collected - 7 FDA‑cleared algorithms - 20+ issued patents - 40+ proven algorithms - 26+ countries served - **Notable Investors/Partners**: Not disclosed. The company is closely linked to **Kardigan** (a cardiovascular drug development company), with which it merged to form a combined heart health company. - **Growth Signals**: - Named a **Best Places to Work 2026** and **World's Top HealthTech Companies of 2025**. - Active hiring (9 open roles as of mid‑2026) across data science, engineering, product, and regulatory. - Hybrid work model with flexible on‑site presence in Chicago. ## Competitive Advantages - **High‑density, real‑world heart data**: Combines continuous on‑body monitoring with AI analytics, offering richer insights than traditional episodic care. - **Integration with drug development**: Through the merger with Kardigan, Prolaio’s platform directly supports parallel clinical trials for multiple cardiovascular therapies, shortening development timelines. - **Regulatory maturity**: Seven FDA‑cleared algorithms demonstrate a strong regulatory pathway and clinical validation. - **Patent portfolio**: 20+ issued patents protect the core technology. ## Strategic Focus - Advance the clinical intelligence platform to support faster, more efficient cardiovascular drug development. - Scale the platform to more patients and research sites (already in 26+ countries). - Leverage the combination with Kardigan to create a vertically integrated heart health company that spans both data analytics and therapeutics. - Continue to expand AI capabilities (hiring for Director of AI Enablement, Product Manager AI, etc.). ## Why Work Here - **Culture**: Value‑driven organization emphasizing scientific rigor, patient‑centricity, a growth mindset, collaboration, and relentless determination. Listed as a "Best Places to Work 2026" by Built In. - **Work model**: Hybrid – flexible on‑site work at Chicago HQ; employees typically spend a mix of remote and on‑site time. - **Benefits**: Competitive health insurance, generous paid time off, 401k retirement plan, professional development opportunities. - **Engineering culture**: High emphasis on AI, data science, and cloud infrastructure; open roles include Data Architect Clinical, Director AI Enablement, Lead Software Quality Engineer, Mobile Android Engineer, and Senior Integrations Engineer. - **Team**: Diverse group of experts in cardiovascular medicine, science, technology, and healthcare (82 total employees as of mid‑2026). ## Sources 1. [Prolaio.com](https://www.prolaio.com/) 2. [Prolaio About Page](https://www.prolaio.com/about) 3. [Prolaio Careers Page](https://www.prolaio.com/careers) 4. [Prolaio Job Board (Greenhouse)](https://job-boards.greenhouse.io/prolaio) 5. [Built In Prolaio Profile](https://builtin.com/company/prolaio) ## Other roles at Prolaio - [Sr. Director, Data Engineering + Integrations](https://feeny.ai/job/sr-director-data-engineering-integrations-prolaio-chicago-6cmmtwy80pex) — Chicago, IL - [Sr. Director, Platform Engineering & Tooling](https://feeny.ai/job/sr-director-platform-engineering-tooling-prolaio-chicago-cacwthg0azn9) — Chicago, IL - [Data Engineer](https://feeny.ai/job/data-engineer-prolaio-chicago-b6s9gxnenwhd) — Chicago, IL - [Customer Success Team Lead (5pm-1am CT)](https://feeny.ai/job/customer-success-team-lead-5pm-1am-ct-prolaio-chicago-h9hxg2atzta6) — Chicago, IL - [Customer Success Specialist (6pm-2am CT)](https://feeny.ai/job/customer-success-specialist-6pm-2am-ct-prolaio-chicago-kxsd4rmsrz9h) — Chicago, IL - [Supply & Inventory Planner](https://feeny.ai/job/supply-inventory-planner-prolaio-chicago-cxz0892a97hc) — Chicago, IL - [Product Manager, Digital Biomarkers](https://feeny.ai/job/product-manager-digital-biomarkers-prolaio-chicago-ck7ktqmb99vt) — Chicago, IL - [Data Architect, Clinical](https://feeny.ai/job/data-architect-clinical-prolaio-chicago-ba9gg4w2mvgt) — Chicago, IL - [Lead Software Quality Engineering, Backend](https://feeny.ai/job/lead-software-quality-engineering-backend-prolaio-chicago-j5b5fw4hgg7f) — Chicago, IL - [Principal Product Designer](https://feeny.ai/job/principal-product-designer-northbeam-san-francisco-85hd0f5mz878) — San Francisco, CA